| Organism name | Helenium linifolium |
|---|---|
| Genus | Helenium |
| Family | Asteraceae |
| Kingdom | Plantae |
| Linked NCBI taxonomy name | Helenium |
|---|---|
| Linked NCBI taxonomy ID | 53720 |
| Linked level | genus |
| Family in NCBI taxonomy | Asteraceae |
|---|---|
| ID | 4210 |
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
| Plant class | asterids |
|---|---|
| ID | 71274 |
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
|
C00003318
|
Linifolin A
|
CHEMBL312003
CHEMBL270297 CHEMBL486196 CHEMBL486997 |
22 / 17 / 18 | No. 470 | No. 38 |
|
||
|
C00021135
|
Linifolin B
|
CHEMBL309895
|
No. 3701 |
|
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P17861 | X-box-binding protein 1 | Unclassified protein | C00003318 | 1 / 0 |
| Q99700 | Ataxin-2 | Unclassified protein | C00003318 | 1 / 1 |
| P30556 | Type-1 angiotensin II receptor | Angiotensin receptor | C00003318 | 1 / 1 |
| P11473 | Vitamin D3 receptor | NR1I1 | C00003318 | 2 / 3 |
| P42858 | Huntingtin | Unclassified protein | C00003318 | 1 / 1 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003318 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003318 | 0 / 0 |
| P51151 | Ras-related protein Rab-9A | Unclassified protein | C00003318 | 0 / 0 |
| Q9Y2T6 | G-protein coupled receptor 55 | Lysophosphatidylinositol receptor | C00003318 | 0 / 0 |
| P43220 | Glucagon-like peptide 1 receptor | Glucagon-like peptide receptor | C00003318 | 0 / 0 |
| Q9Y253 | DNA polymerase eta | Enzyme | C00003318 | 1 / 1 |
| Q9HC16 | DNA dC->dU-editing enzyme APOBEC-3G | Enzyme | C00003318 | 0 / 0 |
| P28482 | Mitogen-activated protein kinase 1 | Erk | C00003318 | 0 / 0 |
| Q00987 | E3 ubiquitin-protein ligase Mdm2 | Other nuclear protein | C00003318 | 1 / 5 |
| O15118 | Niemann-Pick C1 protein | Unclassified protein | C00003318 | 1 / 1 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003318 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003318 | 0 / 0 |
| P10636 | Microtubule-associated protein tau | Unclassified protein | C00003318 | 4 / 3 |
| Q16236 | Nuclear factor erythroid 2-related factor 2 | Unclassified protein | C00003318 | 0 / 0 |
| Q96KQ7 | Histone-lysine N-methyltransferase EHMT2 | Enzyme | C00003318 | 0 / 0 |
| O75874 | Isocitrate dehydrogenase [NADP] cytoplasmic | Enzyme | C00003318 | 1 / 0 |
| Q06710 | Paired box protein Pax-8 | Unclassified protein | C00003318 | 1 / 2 |
| OMIM | preferred title | UniProt |
|---|---|---|
| #614401 | Accelerated tumor formation, susceptibility to; actfs |
Q00987
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #600274 | Frontotemporal dementia; ftd |
P10636
|
| #137800 | Glioma susceptibility 1; glm1 |
O75874
|
| #143100 | Huntington disease; hd |
P42858
|
| #218700 | Hypothyroidism, congenital, nongoitrous, 2; chng2 |
Q06710
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #612371 | Major affective disorder 7; mafd7 |
P17861
|
| #607948 | Mycobacterium tuberculosis, susceptibility to |
P11473
|
| #257220 | Niemann-pick disease, type c1; npc1 |
O15118
|
| #260540 | Parkinson-dementia syndrome |
P10636
|
| #172700 | Pick disease of brain |
P10636
|
| #267430 | Renal tubular dysgenesis; rtd |
P30556
|
| #183090 | Spinocerebellar ataxia 2; sca2 |
Q99700
|
| #601104 | Supranuclear palsy, progressive, 1; psnp1 |
P10636
|
| #277440 | Vitamin d-dependent rickets, type 2a; vddr2a |
P11473
|
| #278750 | Xeroderma pigmentosum, variant type; xpv |
Q9Y253
|
| KEGG | name | UniProt |
|---|---|---|
| H00136 | Niemann-Pick disease type C (NPC) |
O15118
(related)
|
| H00058 | Amyotrophic lateral sclerosis (ALS) |
P10636
(related)
|
| H00077 | Progressive supranuclear palsy (PSP) |
P10636
(related)
|
| H00078 | Frontotemporal lobar degeneration (FTLD) |
P10636
(related)
|
| H00342 | Tuberculosis |
P11473
(related)
|
| H00784 | Localized autosomal recessive hypotrichosis |
P11473
(related)
|
| H01143 | Vitamin D-dependent rickets |
P11473
(related)
|
| H00575 | Renal tubular dysgenesis |
P30556
(related)
|
| H00059 | Huntington's disease (HD) |
P42858
(related)
|
| H00025 | Penile cancer |
Q00987
(related)
|
| H00028 | Choriocarcinoma |
Q00987
(related)
|
| H00036 | Osteosarcoma |
Q00987
(related)
|
| H00037 | Alveolar rhabdomyosarcoma |
Q00987
(related)
|
| H00042 | Glioma |
Q00987
(related)
|
| H00032 | Thyroid cancer |
Q06710
(related)
|
| H00250 | Congenital nongoitrous hypothyroidism (CHNG) |
Q06710
(related)
|
| H00063 | Spinocerebellar ataxia (SCA) |
Q99700
(related)
|
| H00403 | Disorders of nucleotide excision repair |
Q9Y253
(related)
|