Species

KNApSAcK Entry

Organism name Gaillardia pinnatifida
Genus Gaillardia
Family Asteraceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Gaillardia pinnatifida
Linked NCBI taxonomy ID 373166
Linked level species

Family

Family in NCBI taxonomy Asteraceae
ID 4210

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00021098 External link 512 Gaillardilin
No. 303
C00003326 External link 512 Mexicanin I
CHEMBL338474
CHEMBL354946
CHEMBL486996
CHEMBL1728820
CHEMBL1911137
37 / 36 / 29 No. 495 No. 38

Human Protein / Gene in interactions

37 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00003326 4 / 1
P17861 X-box-binding protein 1 Unclassified protein C00003326 1 / 0
Q99700 Ataxin-2 Unclassified protein C00003326 1 / 1
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003326 2 / 0
P06746 DNA polymerase beta Enzyme C00003326 0 / 0
P04062 Glucosylceramidase Enzyme C00003326 6 / 4
Q9Y5X4 Photoreceptor-specific nuclear receptor NR2E3 C00003326 2 / 2
P30556 Type-1 angiotensin II receptor Angiotensin receptor C00003326 1 / 1
P11473 Vitamin D3 receptor NR1I1 C00003326 2 / 3
P00352 Retinal dehydrogenase 1 Enzyme C00003326 0 / 0
Q92830 Histone acetyltransferase KAT2A Enzyme C00003326 0 / 0
P42858 Huntingtin Unclassified protein C00003326 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00003326 2 / 0
O75496 Geminin Unclassified protein C00003326 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00003326 0 / 0
P38398 Breast cancer type 1 susceptibility protein Enzyme C00003326 4 / 2
Q9Y2T6 G-protein coupled receptor 55 Lysophosphatidylinositol receptor C00003326 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00003326 0 / 0
Q04206 Transcription factor p65 Transcription Factor C00003326 0 / 0
Q9Y253 DNA polymerase eta Enzyme C00003326 1 / 1
P83916 Chromobox protein homolog 1 Unclassified protein C00003326 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00003326 0 / 0
P06280 Alpha-galactosidase A Enzyme C00003326 1 / 1
P28482 Mitogen-activated protein kinase 1 Erk C00003326 0 / 0
Q00987 E3 ubiquitin-protein ligase Mdm2 Other nuclear protein C00003326 1 / 5
O15118 Niemann-Pick C1 protein Unclassified protein C00003326 1 / 1
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00003326 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00003326 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00003326 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00003326 0 / 0
Q96KQ7 Histone-lysine N-methyltransferase EHMT2 Enzyme C00003326 0 / 0
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003326 1 / 1
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00003326 1 / 0
Q8IUX4 DNA dC->dU-editing enzyme APOBEC-3F Enzyme C00003326 0 / 0
Q00653 Nuclear factor NF-kappa-B p100 subunit Transcription Factor C00003326 0 / 0
P19838 Nuclear factor NF-kappa-B p105 subunit Transcription Factor C00003326 0 / 0
P01215 Glycoprotein hormones alpha chain Unclassified protein C00003326 0 / 3

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (36)

OMIM preferred title UniProt
#614401 Accelerated tumor formation, susceptibility to; actfs Q00987
#114480 Breast cancer P38398
#604370 Breast-ovarian cancer, familial, susceptibility to, 1; brovca1 P38398
#114500 Colorectal cancer; crc P84022
#268100 Enhanced s-cone syndrome; escs Q9Y5X4
#301500 Fabry disease P06280
#600274 Frontotemporal dementia; ftd P10636
#608013 Gaucher disease, perinatal lethal P04062
#230800 Gaucher disease, type i P04062
#230900 Gaucher disease, type ii P04062
#231000 Gaucher disease, type iii P04062
#231005 Gaucher disease, type iiic P04062
#137800 Glioma susceptibility 1; glm1 O75874
#143100 Huntington disease; hd P42858
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#612371 Major affective disorder 7; mafd7 P17861
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#257220 Niemann-pick disease, type c1; npc1 O15118
#167000 Ovarian cancer P38398
#614320 Pancreatic cancer, susceptibility to, 4; pnca4 P38398
#168600 Parkinson disease, late-onset; pd P04062
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#267430 Renal tubular dysgenesis; rtd P30556
#611131 Retinitis pigmentosa 37; rp37 Q9Y5X4
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473
#278750 Xeroderma pigmentosum, variant type; xpv Q9Y253

KEGG DISEASE (29)

KEGG name UniProt
H00136 Niemann-Pick disease type C (NPC) O15118 (related)
H00081 Hashimoto's thyroiditis P01215 (marker)
H00082 Graves' disease P01215 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P01215 (marker)
H00066 Lewy body dementia (LBD) P04062 (related)
H00126 Gaucher disease P04062 (related)
H00426 Defects in the degradation of ganglioside P04062 (related)
H00810 Progressive myoclonic epilepsy (PME) P04062 (related)
H00125 Fabry disease P06280 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00575 Renal tubular dysgenesis P30556 (related)
H00027 Ovarian cancer P38398 (related)
H00031 Breast cancer P38398 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00025 Penile cancer Q00987 (related)
H00028 Choriocarcinoma Q00987 (related)
H00036 Osteosarcoma Q00987 (related)
H00037 Alveolar rhabdomyosarcoma Q00987 (related)
H00042 Glioma Q00987 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)
Q9NUW8 (related)
H00403 Disorders of nucleotide excision repair Q9Y253 (related)
H00527 Retinitis pigmentosa (RP) Q9Y5X4 (related)
H00805 Vitreoretinal degeneration Q9Y5X4 (related)