Species

KNApSAcK Entry

Organism name Isodon pharicus
Genus Isodon
Family Labiatae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Isodon pharicus
Linked NCBI taxonomy ID 204134
Linked level species

Family

Family in NCBI taxonomy Lamiaceae
ID 4136

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class asterids
ID 71274

Metabolite list (12)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00047616 External link 512 Wangzaozin A
CHEMBL2021467
CHEMBL2021470
No. 132
C00047548 External link 512 Pseurata B
CHEMBL564375
CHEMBL557031
No. 132
C00047363 External link 512 3-Epipseurata B
/ (-)-3-Epipseurata B
CHEMBL564375
CHEMBL557031
No. 132
C00047547 External link 512 Pseurata A
CHEMBL2021467
CHEMBL2021470
No. 132
C00047517 External link 512 Minheryin G
/ (-)-Minheryin G
CHEMBL562256
No. 132
C00047479 External link 512 Kamebanin
CHEMBL472437
18 / 28 / 25 No. 132
C00047492 External link 512 Leukamenin E
CHEMBL562257
No. 289 No. 41
C00047435 External link 512 Dihydropseurata F
No. 289 No. 41
C00047367 External link 512 7-O-Acetylpseurata C
/ (+)-7-O-Acetylpseurata C
CHEMBL550161
No. 289 No. 41
C00040098 External link 512 Pseurata C
CHEMBL483119
No. 289 No. 41
C00047549 External link 512 Pseurata F
CHEMBL551316
No. 289 No. 41
C00003442 External link 512 Isodomedin
CHEMBL564759
No. 289 No. 41

Human Protein / Gene in interactions

18 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
Q16637 Survival motor neuron protein Unclassified protein C00047479 4 / 1
Q99700 Ataxin-2 Unclassified protein C00047479 1 / 1
Q13315 Serine-protein kinase ATM Atypical serine/threonine protein kinase PIKK subfamily C00047479 1 / 4
P02545 Prelamin-A/C Unclassified protein C00047479 11 / 10
P11473 Vitamin D3 receptor NR1I1 C00047479 2 / 3
P42858 Huntingtin Unclassified protein C00047479 1 / 1
P84022 Mothers against decapentaplegic homolog 3 Unclassified protein C00047479 2 / 0
O75496 Geminin Unclassified protein C00047479 0 / 0
P51151 Ras-related protein Rab-9A Unclassified protein C00047479 0 / 0
P43220 Glucagon-like peptide 1 receptor Glucagon-like peptide receptor C00047479 0 / 0
P83916 Chromobox protein homolog 1 Unclassified protein C00047479 0 / 0
Q9HC16 DNA dC->dU-editing enzyme APOBEC-3G Enzyme C00047479 0 / 0
Q96QE3 ATPase family AAA domain-containing protein 5 Unclassified protein C00047479 0 / 0
Q9UNA4 DNA polymerase iota Enzyme C00047479 0 / 0
P10636 Microtubule-associated protein tau Unclassified protein C00047479 4 / 3
Q16236 Nuclear factor erythroid 2-related factor 2 Unclassified protein C00047479 0 / 0
O75874 Isocitrate dehydrogenase [NADP] cytoplasmic Enzyme C00047479 1 / 0
Q06710 Paired box protein Pax-8 Unclassified protein C00047479 1 / 2

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (28)

OMIM preferred title UniProt
#208900 Ataxia-telangiectasia; at Q13315
#115200 Cardiomyopathy, dilated, 1a; cmd1a P02545
#212112 Cardiomyopathy, dilated, with hypergonadotropic hypogonadism P02545
#605588 Charcot-marie-tooth disease, axonal, type 2b1; cmt2b1 P02545
#114500 Colorectal cancer; crc P84022
#181350 Emery-dreifuss muscular dystrophy 2, autosomal dominant; edmd2 P02545
#600274 Frontotemporal dementia; ftd P10636
#137800 Glioma susceptibility 1; glm1 O75874
#610140 Heart-hand syndrome, slovenian type P02545
#143100 Huntington disease; hd P42858
#176670 Hutchinson-gilford progeria syndrome; hgps P02545
#218700 Hypothyroidism, congenital, nongoitrous, 2; chng2 Q06710
#151660 Lipodystrophy, familial partial, type 2; fpld2 P02545
#613795 Loeys-dietz syndrome, type 3; lds3 P84022
#248370 Mandibuloacral dysplasia with type a lipodystrophy; mada P02545
#613205 Muscular dystrophy, congenital, lmna-related P02545
#159001 Muscular dystrophy, limb-girdle, type 1b; lgmd1b P02545
#607948 Mycobacterium tuberculosis, susceptibility to P11473
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#275210 Restrictive dermopathy, lethal P02545
#253300 Spinal muscular atrophy, type i; sma1 Q16637
#253550 Spinal muscular atrophy, type ii; sma2 Q16637
#253400 Spinal muscular atrophy, type iii; sma3 Q16637
#271150 Spinal muscular atrophy, type iv; sma4 Q16637
#183090 Spinocerebellar ataxia 2; sca2 Q99700
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#277440 Vitamin d-dependent rickets, type 2a; vddr2a P11473

KEGG DISEASE (25)

KEGG name UniProt
H00264 Charcot-Marie-Tooth disease (CMT) P02545 (related)
H00294 Dilated cardiomyopathy (DCM) P02545 (related)
H00420 Familial partial lipodystrophy (FPL) P02545 (related)
H00563 Emery-Dreifuss muscular dystrophy P02545 (related)
H00590 Congenital muscular dystrophies (CMD/MDC) P02545 (related)
H00593 Limb-girdle muscular dystrophy (LGMD) P02545 (related)
H00601 Hutchinson-Gilford progeria syndrome P02545 (related)
H00663 Restrictive dermopathy P02545 (related)
H00665 Mandibuloacral dysplasia P02545 (related)
H01216 Left ventricular noncompaction (LVNC) P02545 (related)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H00342 Tuberculosis P11473 (related)
H00784 Localized autosomal recessive hypotrichosis P11473 (related)
H01143 Vitamin D-dependent rickets P11473 (related)
H00059 Huntington's disease (HD) P42858 (related)
H00032 Thyroid cancer Q06710 (related)
H00250 Congenital nongoitrous hypothyroidism (CHNG) Q06710 (related)
H00005 Chronic lymphocytic leukemia (CLL) Q13315 (related)
H00064 Ataxia telangiectasia (AT) Q13315 (related)
H00094 DNA repair defects Q13315 (related)
H00848 Ataxia with ocular apraxia (AOA) Q13315 (related)
H00455 Spinal muscular atrophy (SMA) Q16637 (related)
H00063 Spinocerebellar ataxia (SCA) Q99700 (related)