Bupleurum chinense
Species
KNApSAcK Entry
| Organism name | Bupleurum chinense |
|---|---|
| Genus | Bupleurum |
| Family | Apiaceae |
| Kingdom | Plantae |
NCBI taxonomy
Entry
| Linked NCBI taxonomy name | Bupleurum chinense |
|---|---|
| Linked NCBI taxonomy ID | 52451 |
| Linked level | species |
Family
| Family in NCBI taxonomy | Apiaceae |
|---|---|
| ID | 4037 |
Kingdom (Superkingdom)
| Kingdom (Superkingdom) in NCBI taxonomy | Viridiplantae |
|---|---|
| ID | 33090 |
Plant class
| Plant class | asterids |
|---|---|
| ID | 71274 |
Natural Activity
List (43)
| Species | Activity |
|---|---|
| Bupleurum chinense DC. | Adrenergic |
| Bupleurum chinense DC. | Analgesic |
| Bupleurum chinense DC. | Antiadhesive |
| Bupleurum chinense DC. | Antiaggregant |
| Bupleurum chinense DC. | Antidepressant |
| Bupleurum chinense DC. | Antiedemic |
| Bupleurum chinense DC. | Antifibrositic |
| Bupleurum chinense DC. | Antihepatosis |
| Bupleurum chinense DC. | Antiinflammatory |
| Bupleurum chinense DC. | Antimutagenic |
| Bupleurum chinense DC. | Antinephrotic |
| Bupleurum chinense DC. | Antiprostaglandin |
| Bupleurum chinense DC. | Antipyretic |
| Bupleurum chinense DC. | Antithromboxane |
| Bupleurum chinense DC. | Antitoxic |
| Bupleurum chinense DC. | Antitumor |
| Bupleurum chinense DC. | Antitussive |
| Bupleurum chinense DC. | Antiulcer |
| Bupleurum chinense DC. | Antiviral |
| Bupleurum chinense DC. | Apoptotic |
| Bupleurum chinense DC. | Bitter |
| Bupleurum chinense DC. | cAMP-Depressant |
| Bupleurum chinense DC. | Corticosteronigenic |
| Bupleurum chinense DC. | Diaphoretic |
| Bupleurum chinense DC. | Diuretic |
| Bupleurum chinense DC. | Expectorant |
| Bupleurum chinense DC. | Gastroprotective |
| Bupleurum chinense DC. | Hemolytic |
| Bupleurum chinense DC. | Hemostat |
| Bupleurum chinense DC. | Hepatoprotective |
| Bupleurum chinense DC. | Hepatotonic |
| Bupleurum chinense DC. | Hyperglycemic |
| Bupleurum chinense DC. | Hypocholesterolemic |
| Bupleurum chinense DC. | Hypoglycemic |
| Bupleurum chinense DC. | Hypotensive |
| Bupleurum chinense DC. | Immunostimulant |
| Bupleurum chinense DC. | Interleukinogenic |
| Bupleurum chinense DC. | Laxative |
| Bupleurum chinense DC. | Mitogenic |
| Bupleurum chinense DC. | Nephroprotective |
| Bupleurum chinense DC. | Phagocytotic |
| Bupleurum chinense DC. | Sedative |
| Bupleurum chinense DC. | Tyrosinase-Inhibitor |
Metabolite list (1)
| KNApSAcK ID | name | ChEMBL link | CTD link |
# of proteins in
ChEMBL interaction / related OMIM / related KEGG DISEASE |
# of genes in
CTD interaction / related diseases |
KCF-S
cluster |
phytochemical
cluster |
figure |
|---|---|---|---|---|---|---|---|---|
C00003548
|
Saikosaponin A
|
CHEMBL1159434
CHEMBL1159438 CHEMBL1703199 |
5 / 9 / 37 | No. 11 | No. 51 |
|
Human Protein / Gene in interactions
5 ChEMBL Protein in interactions
| accession | description | class description | KNApSAcK metabolite in interactions |
# of diseases
(OMIM / KEGG) |
|---|---|---|---|---|
| P04637 | Cellular tumor antigen p53 | Transcription Factor | C00003548 | 7 / 37 |
| P84022 | Mothers against decapentaplegic homolog 3 | Unclassified protein | C00003548 | 2 / 0 |
| O75496 | Geminin | Unclassified protein | C00003548 | 0 / 0 |
| Q96QE3 | ATPase family AAA domain-containing protein 5 | Unclassified protein | C00003548 | 0 / 0 |
| Q9UNA4 | DNA polymerase iota | Enzyme | C00003548 | 0 / 0 |
Related Diseases
Diseases related to proteins in ChEMBL interactions
OMIM (9)
| OMIM | preferred title | UniProt |
|---|---|---|
| #202300 | Adrenocortical carcinoma, hereditary; adcc |
P04637
|
| #614740 | Basal cell carcinoma, susceptibility to, 7; bcc7 |
P04637
|
| #114500 | Colorectal cancer; crc |
P84022
|
| #133239 | Esophageal cancer |
P04637
|
| #151623 | Li-fraumeni syndrome 1; lfs1 |
P04637
|
| #613795 | Loeys-dietz syndrome, type 3; lds3 |
P84022
|
| #211980 | Lung cancer |
P04637
|
| #260500 | Papilloma of choroid plexus; cpp |
P04637
|
| #275355 | Squamous cell carcinoma, head and neck; hnscc |
P04637
|
KEGG DISEASE (37)
| KEGG | name | UniProt |
|---|---|---|
| H00004 | Chronic myeloid leukemia (CML) |
P04637
(related)
|
| H00005 | Chronic lymphocytic leukemia (CLL) |
P04637
(related)
|
| H00006 | Hairy-cell leukemia |
P04637
(related)
|
| H00008 | Burkitt lymphoma |
P04637
(related)
|
| H00009 | Adult T-cell leukemia |
P04637
(related)
|
| H00010 | Multiple myeloma |
P04637
(related)
|
| H00013 | Small cell lung cancer |
P04637
(related)
|
| H00014 | Non-small cell lung cancer |
P04637
(related)
|
| H00015 | Malignant pleural mesothelioma |
P04637
(related)
|
| H00016 | Oral cancer |
P04637
(related)
P04637 (marker) |
| H00017 | Esophageal cancer |
P04637
(related)
P04637 (marker) |
| H00018 | Gastric cancer |
P04637
(related)
|
| H00019 | Pancreatic cancer |
P04637
(related)
P04637 (marker) |
| H00020 | Colorectal cancer |
P04637
(related)
P04637 (marker) |
| H00022 | Bladder cancer |
P04637
(related)
|
| H00025 | Penile cancer |
P04637
(related)
P04637 (marker) |
| H00026 | Endometrial Cancer |
P04637
(related)
|
| H00027 | Ovarian cancer |
P04637
(related)
|
| H00028 | Choriocarcinoma |
P04637
(related)
|
| H00029 | Vulvar cancer |
P04637
(related)
|
| H00031 | Breast cancer |
P04637
(related)
|
| H00032 | Thyroid cancer |
P04637
(related)
|
| H00033 | Adrenal carcinoma |
P04637
(related)
|
| H00036 | Osteosarcoma |
P04637
(related)
|
| H00038 | Malignant melanoma |
P04637
(related)
|
| H00039 | Basal cell carcinoma |
P04637
(related)
|
| H00040 | Squamous cell carcinoma |
P04637
(related)
|
| H00041 | Kaposi's sarcoma |
P04637
(related)
|
| H00042 | Glioma |
P04637
(related)
P04637 (marker) |
| H00044 | Cancer of the anal canal |
P04637
(related)
|
| H00046 | Cholangiocarcinoma |
P04637
(related)
|
| H00047 | Gallbladder cancer |
P04637
(related)
|
| H00048 | Hepatocellular carcinoma |
P04637
(related)
|
| H00055 | Laryngeal cancer |
P04637
(related)
P04637 (marker) |
| H00881 | Li-Fraumeni syndrome |
P04637
(related)
|
| H01007 | Choroid plexus papilloma |
P04637
(related)
|
| H00021 | Renal cell carcinoma |
P04637
(marker)
|