Species

KNApSAcK Entry

Organism name Asparagus tenuifolium
Genus Asparagus
Family Asparagaceae
Kingdom Plantae

NCBI taxonomy

Entry

Linked NCBI taxonomy name Asparagus
Linked NCBI taxonomy ID 4685
Linked level genus

Family

Family in NCBI taxonomy Asparagaceae
ID 40552

Kingdom (Superkingdom)

Kingdom (Superkingdom) in NCBI taxonomy Viridiplantae
ID 33090

Plant class

Plant class Liliopsida
ID 4447

Metabolite list (2)

KNApSAcK ID name ChEMBL link CTD link # of proteins in
ChEMBL interaction
/ related OMIM
/ related KEGG DISEASE
# of genes in
CTD interaction
/ related diseases
KCF-S
cluster
phytochemical
cluster
figure
C00003672 External link 512 Sitosterol
/ beta-sitosterl
/ (-)-beta-Sitosterol
/ Stigmast-5-en-3beta-ol
CHEMBL221542
CHEMBL1398443
CHEMBL1875388
17 / 19 / 12 No. 53 No. 11
C00003597 External link 512 Yamogenin
CHEMBL412437
CHEMBL1551855
CHEMBL1553328
6 / 10 / 7 No. 171 No. 11

Human Protein / Gene in interactions

22 ChEMBL Protein in interactions

accession description class description KNApSAcK metabolite in interactions # of diseases
(OMIM / KEGG)
P08684 Cytochrome P450 3A4 Cytochrome P450 3A4 C00003597 C00003672 0 / 1
P00734 Prothrombin S1A C00003672 4 / 2
P18031 Tyrosine-protein phosphatase non-receptor type 1 Tyr C00003672 0 / 0
P49798 Regulator of G-protein signaling 4 Unclassified protein C00003672 2 / 0
P06746 DNA polymerase beta Enzyme C00003672 0 / 0
P08047 Transcription factor Sp1 Unclassified protein C00003672 0 / 0
P16473 Thyrotropin receptor Glycohormone receptor C00003672 3 / 2
P08183 Multidrug resistance protein 1 drug C00003672 1 / 0
P11712 Cytochrome P450 2C9 Cytochrome P450 2C9 C00003672 0 / 1
P49841 Glycogen synthase kinase-3 beta Gsk C00003672 0 / 0
P40763 Signal transducer and activator of transcription 3 Transcription Factor C00003597 1 / 2
P22310 UDP-glucuronosyltransferase 1-4 Enzyme C00003597 3 / 0
P14679 Tyrosinase Oxidoreductase C00003672 4 / 2
P05177 Cytochrome P450 1A2 Cytochrome P450 1A2 C00003672 0 / 0
Q9HAW9 UDP-glucuronosyltransferase 1-8 Enzyme C00003597 0 / 0
P03372 Estrogen receptor NR3A1 C00003672 1 / 1
P33261 Cytochrome P450 2C19 Cytochrome P450 2C19 C00003672 1 / 1
P10635 Cytochrome P450 2D6 Cytochrome P450 2D6 C00003672 1 / 0
P22309 UDP-glucuronosyltransferase 1-1 Enzyme C00003597 5 / 1
P10636 Microtubule-associated protein tau Unclassified protein C00003597 4 / 3
P80365 Corticosteroid 11-beta-dehydrogenase isozyme 2 Enzyme C00003672 1 / 1
Q9NUW8 Tyrosyl-DNA phosphodiesterase 1 Enzyme C00003672 1 / 1

Related Diseases

Diseases related to proteins in ChEMBL interactions

OMIM (29)

OMIM preferred title UniProt
#103470 Albinism, ocular, with sensorineural deafness P14679
#203100 Albinism, oculocutaneous, type ia; oca1a P14679
#606952 Albinism, oculocutaneous, type ib; oca1b P14679
#218030 Apparent mineralocorticoid excess; ame P80365
#601816 Bilirubin, serum level of, quantitative trait locus 1; biliqtl1 P22309
#218800 Crigler-najjar syndrome, type i P22309
P22310
#606785 Crigler-najjar syndrome, type ii P22309
P22310
#609535 Drug metabolism, poor, cyp2c19-related P33261
#608902 Drug metabolism, poor, cyp2d6-related P10635
#615363 Estrogen resistance; estrr P03372
#600274 Frontotemporal dementia; ftd P10636
#143500 Gilbert syndrome P22309
P22310
#147060 Hyper-ige recurrent infection syndrome, autosomal dominant P40763
#237900 Hyperbilirubinemia, transient familial neonatal; hblrtfn P22309
#603373 Hyperthyroidism, familial gestational P16473
#609152 Hyperthyroidism, nonautoimmune P16473
#275200 Hypothyroidism, congenital, nongoitrous, 1; chng1 P16473
#612244 Inflammatory bowel disease 13; ibd13 P08183
#260540 Parkinson-dementia syndrome P10636
#172700 Pick disease of brain P10636
#614390 Pregnancy loss, recurrent, susceptibility to, 2; rprgl2 P00734
#613679 Prothrombin deficiency, congenital P00734
#604906 Schizophrenia 9; sczd9 P49798
#181500 Schizophrenia; sczd P49798
#601800 Skin/hair/eye pigmentation, variation in, 3; shep3 P14679
#607250 Spinocerebellar ataxia, autosomal recessive, with axonal neuropathy; scan1 Q9NUW8
#601367 Stroke, ischemic P00734
#601104 Supranuclear palsy, progressive, 1; psnp1 P10636
#188050 Thrombophilia due to thrombin defect; thph1 P00734

KEGG DISEASE (18)

KEGG name UniProt
H00223 Inherited thrombophilia P00734 (related)
H01254 Congenital prothrombin deficiency P00734 (related)
H00026 Endometrial Cancer P03372 (marker)
H00036 Osteosarcoma P08684 (marker)
H00058 Amyotrophic lateral sclerosis (ALS) P10636 (related)
H00077 Progressive supranuclear palsy (PSP) P10636 (related)
H00078 Frontotemporal lobar degeneration (FTLD) P10636 (related)
H01205 Coumarin resistance P11712 (related)
H00168 Oculocutaneous albinism (OCA) P14679 (related)
H00038 Malignant melanoma P14679 (marker)
H00250 Congenital nongoitrous hypothyroidism (CHNG) P16473 (related)
H01269 Congenital hyperthyroidism P16473 (related)
H00208 Hyperbilirubinemia P22309 (related)
H01171 Poor drug metabolism (PM) P33261 (related)
H00016 Oral cancer P40763 (related)
H00107 Other well-defined immunodeficiency syndromes P40763 (related)
H00259 Apparent mineralocorticoid excess syndrome P80365 (related)
H00063 Spinocerebellar ataxia (SCA) Q9NUW8 (related)