KEGG   ORTHOLOGY: K00659
Entry
K00659                      KO                                     

Name
BAAT
Definition
bile acid-CoA:amino acid N-acyltransferase [EC:2.3.1.65 3.1.2.2]
Pathway
ko00120  Primary bile acid biosynthesis
ko00430  Taurine and hypotaurine metabolism
ko01040  Biosynthesis of unsaturated fatty acids
ko01100  Metabolic pathways
ko04146  Peroxisome
ko04976  Bile secretion
Module
M00106  Conjugated bile acid biosynthesis, cholate => taurocholate/glycocholate
Disease
H01935  Familial hypercholanemia
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00120 Primary bile acid biosynthesis
    K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
   01040 Biosynthesis of unsaturated fatty acids
    K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
  09106 Metabolism of other amino acids
   00430 Taurine and hypotaurine metabolism
    K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
 09140 Cellular Processes
  09141 Transport and catabolism
   04146 Peroxisome
    K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.1  Transferring groups other than aminoacyl groups
    2.3.1.65  bile acid-CoA:amino acid N-acyltransferase
     K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2  palmitoyl-CoA hydrolase
     K00659  BAAT; bile acid-CoA:amino acid N-acyltransferase
Other DBs
RN: R03718 R03720 R08744 R08745
GO: 0047963 0016290
Genes
HSA: 570(BAAT)
PTR: 472997
PPS: 100972861 100992429(BAAT)
GGO: 101140183(BAAT)
PON: 100431907(BAAT) 100461881
NLE: 100598200(BAAT)
MCC: 100429419(BAAT)
MCF: 102132073(BAAT)
CSAB: 103219118(BAAT)
RRO: 104670797(BAAT)
RBB: 108537176(BAAT)
CJC: 100394190 100396712(BAAT)
SBQ: 101036806
MMU: 12012(Baat) 209186(Acnat2) 230161(Acnat1)
MPAH: 110323775(Baat) 110323900
RNO: 29725(Baat) 313220(Acnat2) 681043(Acnat1)
MUN: 110557337 110557338(Baat)
CGE: 100756252(Baat) 100756541
HGL: 101716142(Baat) 101717293
CCAN: 109696243(Baat)
TUP: 102472797 102473647(BAAT)
CFA: 481635
VVP: 112930766(BAAT) 112930863
UAH: 113260385 113260386(BAAT)
FCA: 101095691(BAAT) 101096116
PTG: 102969591(BAAT) 102969870
BTA: 530653 786798(BAAT)
BOM: 102268462
BIU: 109563300(BAAT)
CHX: 102174570(BAAT)
CFR: 102523415(BAAT)
CDK: 105086911(BAAT)
BACU: 103006095 103017253(BAAT)
LVE: 103081315 103082496(BAAT)
OOR: 101284164(BAAT) 101284403
DLE: 111188015(BAAT)
PCAD: 102984994(BAAT)
ECB: 100054567 100063137(BAAT)
EPZ: 103552469(BAAT) 103568036
MNA: 107546604(BAAT)
HAI: 109395040(BAAT)
DRO: 112304453(BAAT)
PALE: 102892341(BAAT) 102897591
MJV: 108397381(BAAT)
TMU: 101357199
MDO: 100023136(BAAT)
PCW: 110219134(BAAT)
OAA: 100084056(BAAT)
GGA: 769879(BAAT)
MGP: 100539658
CJO: 107314177
NMEL: 110400838
APLA: 101797844
ACYG: 106048282
TGU: 115495423
LSR: 110485078
SCAN: 103822142
GFR: 102037789
FAB: 101815920
PHI: 102101793
PMAJ: 107206148
CCAE: 111930612
ETL: 114063343
FPG: 101924136
FCH: 102059453
CLV: 102094683
EGZ: 104134405(BAAT)
NNI: 104008979(BAAT)
ACUN: 113481099
AAM: 106494986
CMY: 102939533(BAAT) 102947935
CPIC: 101932563 101938826(BAAT)
ACS: 100566890(baat)
PVT: 110078385(BAAT)
PBI: 103065567(BAAT)
TSR: 106538123(BAAT)
PMUA: 114600844(BAAT)
GJA: 107106123 107106126(BAAT)
XLA: 100137716(LOC100488333.L) 108707337
SRX: 107726829
CCAR: 109068937
IPU: 108280978
EEE: 113584003
ONL: 109198392
OLA: 101166298
XMA: 102226402
XCO: 114135870
PRET: 103465285
NFU: 107385610
SDU: 111221490
SLAL: 111667779
HCQ: 109522368
MALB: 109956248
ELS: 105010081
SFM: 108933858
MYI: 110465077
OBI: 106881808
LAK: 106169569
NVE: 5519541
ADF: 107346883
AMIL: 114966874
 » show all
Reference
PMID:8034703
  Authors
Falany CN, Johnson MR, Barnes S, Diasio RB
  Title
Glycine and taurine conjugation of bile acids by a single enzyme. Molecular cloning and expression of human liver bile acid CoA:amino acid N-acyltransferase.
  Journal
J Biol Chem 269:19375-9 (1994)
  Sequence
[hsa:570]
Reference
  Authors
Russell DW
  Title
The enzymes, regulation, and genetics of bile acid synthesis.
  Journal
Annu Rev Biochem 72:137-74 (2003)
DOI:10.1146/annurev.biochem.72.121801.161712

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