 | | ORTHOLOGY: K03362 | |
Entry |
|
Symbol |
FBXW1_11, BTRC, beta-TRCP
|
Name |
F-box and WD-40 domain protein 1/11
|
Pathway |
map04341 | Hedgehog signaling pathway - fly |
map05170 | Human immunodeficiency virus 1 infection |
|
Disease |
H02460 | Neurodevelopmental disorder with dysmorphic facies and skeletal anomalies |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
09123 Folding, sorting and degradation
04120 Ubiquitin mediated proteolysis
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09130 Environmental Information Processing
09132 Signal transduction
04310 Wnt signaling pathway
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
04340 Hedgehog signaling pathway
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
04341 Hedgehog signaling pathway - fly
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
04390 Hippo signaling pathway
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09140 Cellular Processes
09143 Cell growth and death
04114 Oocyte meiosis
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
04218 Cellular senescence
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09150 Organismal Systems
09151 Immune system
04624 Toll and Imd signaling pathway
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09159 Environmental adaptation
04710 Circadian rhythm
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09160 Human Diseases
09172 Infectious disease: viral
05170 Human immunodeficiency virus 1 infection
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09171 Infectious disease: bacterial
05131 Shigellosis
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
09180 Brite Hierarchies
09182 Protein families: genetic information processing
04121 Ubiquitin system
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
03036 Chromosome and associated proteins
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
Multi subunit Ring-finger type E3
SCF complex
Target recognizing subunit (F-box)
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
Centrosome formation proteins
Centrosome duplication proteins
Regulators of centriole replication
K03362 FBXW1_11, BTRC, beta-TRCP; F-box and WD-40 domain protein 1/11
|
Genes |
» show all
|
Reference |
|
Authors |
Shirogane T, Jin J, Ang XL, Harper JW |
Title |
SCFbeta-TRCP controls clock-dependent transcription via casein kinase 1-dependent degradation of the mammalian period-1 (Per1) protein. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Suzuki H, Chiba T, Suzuki T, Fujita T, Ikenoue T, Omata M, Furuichi K, Shikama H, Tanaka K |
Title |
Homodimer of two F-box proteins betaTrCP1 or betaTrCP2 binds to IkappaBalpha for signal-dependent ubiquitination. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Yaron A, Hatzubai A, Davis M, Lavon I, Amit S, Manning AM, Andersen JS, Mann M, Mercurio F, Ben-Neriah Y |
Title |
Identification of the receptor component of the IkappaBalpha-ubiquitin ligase. |
Journal |
|
Sequence |
|
Reference |
|
Authors |
Koike J, Sagara N, Kirikoshi H, Takagi A, Miwa T, Hirai M, Katoh M |
Title |
Molecular cloning and genomic structure of the betaTRCP2 gene on chromosome 5q35.1. |
Journal |
|
Sequence |
|
|
|
|