KEGG ORTHOLOGY: K04141

ORTHOLOGY: K04141

Entry

K04141 KO

Name

ADRB1

Definition

adrenergic receptor beta-1

Pathway

ko04020

Calcium signaling pathway

ko04022

cGMP-PKG signaling pathway

ko04024

cAMP signaling pathway

ko04080

Neuroactive ligand-receptor interaction

ko04261

Adrenergic signaling in cardiomyocytes

ko04540

Gap junction

ko04923

Regulation of lipolysis in adipocytes

ko04924

Renin secretion

ko04970

Salivary secretion

ko05414

Dilated cardiomyopathy (DCM)

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04020 Calcium signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04024 cAMP signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
   04022 cGMP-PKG signaling pathway
    K04141  ADRB1; adrenergic receptor beta-1
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    K04141  ADRB1; adrenergic receptor beta-1
09140 Cellular Processes
  09144 Cellular community - eukaryotes
   04540 Gap junction
    K04141  ADRB1; adrenergic receptor beta-1
09150 Organismal Systems
  09152 Endocrine system
   04923 Regulation of lipolysis in adipocytes
    K04141  ADRB1; adrenergic receptor beta-1
   04924 Renin secretion
    K04141  ADRB1; adrenergic receptor beta-1
  09153 Circulatory system
   04261 Adrenergic signaling in cardiomyocytes
    K04141  ADRB1; adrenergic receptor beta-1
  09154 Digestive system
   04970 Salivary secretion
    K04141  ADRB1; adrenergic receptor beta-1
09160 Human Diseases
  09166 Cardiovascular disease
   05414 Dilated cardiomyopathy (DCM)
    K04141  ADRB1; adrenergic receptor beta-1
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04030 G protein-coupled receptors
    K04141  ADRB1; adrenergic receptor beta-1
G protein-coupled receptors [BR:ko04030]
Rhodopsin family
  Biogenic amine
   Adrenaline
    K04141  ADRB1; adrenergic receptor beta-1

Other DBs

GO:

0004940

TC:	9.A.14.3.11

Genes

HSA:	153(ADRB1)

PTR:	466206(ADRB1)

PPS:	100978740(ADRB1)

GGO:	101149664(ADRB1)

PON:	100441708(ADRB1)

NLE:	100606030(ADRB1)

MCC:	100426598(ADRB1)

MCF:	107126443(ADRB1)

CSAB:

103216543(ADRB1)

RRO:	104659193(ADRB1)

RBB:	108542470(ADRB1)

CJC:	100387664(ADRB1)

MMU:	11554(Adrb1)

MCAL:

110285631(Adrb1)

MPAH:

110333803(Adrb1)

RNO:	24925(Adrb1)

MUN:	110545114(Adrb1)

CGE:

113834807

NGI:	103731758(Adrb1)

HGL:	101706546(Adrb1)

CCAN:

109678400(Adrb1)

OCU:	100338084(ADRB1)

TUP:	102478713(ADRB1)

CFA:	493972(ADRB1)

VVP:	112914728(ADRB1)

AML:	100471252(ADRB1)

UAH:	113251957(ADRB1)

ORO:	101365047(ADRB1)

ELK:

111145258

FCA:	493971(ADRB1)

PPAD:

109272931(ADRB1)

AJU:	113600301(ADRB1)

BTA:	281604(ADRB1)

BOM:	102270402(ADRB1)

BIU:	109553237(ADRB1)

BBUB:

102399704(ADRB1)

CHX:	102187558(ADRB1)

OAS:	443528(ADRB1)

SSC:	397355(ADRB1)

CDK:	105104750(ADRB1)

BACU:

103003267(ADRB1)

LVE:	103082012(ADRB1)

OOR:	101286166(ADRB1)

DLE:	111172295(ADRB1)

PCAD:

112064233(ADRB1)

ECB:	100146832(ADRB1)

MYB:	102258046(ADRB1)

MNA:	107536422(ADRB1)

HAI:	109392029(ADRB1)

DRO:	112300171(ADRB1)

PALE:

102880796(ADRB1)

RAY:	107511714(ADRB1)

MJV:	108384355(ADRB1)

LAV:	100654973(ADRB1)

TMU:

101347074

MDO:	100027410(ADRB1)

PCW:	110209527(ADRB1)

OAA:	100082919(ADRB1)

GGA:	101750705(ADRB1)

MGP:	100303680(ADRB1)

CJO:	107316142(ADRB1)

NMEL:

110400444(ADRB1)

APLA:

101790405(ADRB1)

ACYG:

106031933(ADRB1)

TGU:	100221186(ADRB3) 100221823(ADRB1)

LSR:	110468269(ADRB1)

SCAN:

103814126(ADRB1)

GFR:	102034437(ADRB1)

FAB:	101805929(ADRB1)

PHI:	102113245(ADRB1)

PMAJ:

107207049(ADRB1)

CCAE:

111930959(ADRB1)

ETL:	114066977(ADRB1)

FPG:	101917348(ADRB1)

FCH:	102052904(ADRB1)

CLV:	102087468(ADRB1)

EGZ:	104123630(ADRB1)

NNI:	104022377(ADRB1)

ACUN:

113481792(ADRB1)

PADL:

103918669(ADRB1)

AAM:	106489475(ADRB1)

ASN:	102368318(ADRB1)

AMJ:	102574660(ADRB1)

PSS:	102447221(ADRB1)

CMY:	102930847(ADRB1)

CPIC:

101935916(ADRB1)

ACS:	100563228(adrb1)

PVT:	110071978(ADRB1)

PBI:	103066230(ADRB1)

PMUR:

107287322(ADRB1)

TSR:	106545862(ADRB1)

PMUA:

114597471(ADRB1)

GJA:	107122433(ADRB1)

XLA:	108696008 108697308(X-Beta1AR) 399337(adrb1.L)

NPR:	108802079(ADRB1)

DRE:	557194(adrb1) 558248(adrb3a) 792519(adrb3b)

SRX:

107755541

SANH:

107689959 107702449

SGH:	107566002 107581665

CCAR:

109099658 109099976

IPU:	108273437(adrb1)

PHYP:

113527186(adrb1)

AMEX:

103043371(adrb1)

EEE:	113586622(adrb1)

TRU:	101068216(adrb1)

TNG:	GSTEN00034979G001

LCO:	104927885(adrb1)

NCC:	104959602 104963628

MZE:	101474916(adrb1)

ONL:	100710833(adrb1)

OLA:	101156611(adrb1)

XMA:	102226151(adrb1)

XCO:	114152261(adrb1)

PRET:

103481286(adrb1)

CVG:	107094714(adrb1)

NFU:	107387883(adrb1)

KMR:	108247041(adrb1)

ALIM:

106516953(adrb1)

AOCE:

111567295(adrb1)

CSEM:

103381516(adrb1)

POV:	109626653(adrb1)

LCF:	108898720(adrb1)

SDU:	111219546(adrb1)

SLAL:

111669641(adrb1)

HCQ:	109523917(adrb1)

BPEC:

110154323(adrb1)

MALB:

109963035(adrb1)

ELS:	105031082(adrb1)

SFM:	114910243(adrb1)

PKI:	111836057(adrb1)

LCM:	102359969(ADRB1)

CMK:	103186583(adrb1) 103190260(adrb3)

RTP:

109923571

BFO:	BRAFLDRAFT_85478

APLC:

110976721 110979469 110985800 110987254 110989766

SKO:

PVM:

CSCU:

CRG:

EPA:	110231301 110231637 110239373 110241939 110244252 110247678 110251898 110253083

ADF:	107336219 107339149 107349734

AMIL:

114974417

PDAM:

113664213 113665234 113666344 113666349 113667800 113673412 113673516 113674374 113675480 113677495 113681780 113682539 113684408 113685437 113686679

SPIS:

111319521 111327969 111327999 111332329 111332755 111332861 111338560 111338724 111339007 111339008 111339009 111346857

DGT:	114517622 114520499 114522384 114530024 114530038 114530368 114530862 114530894 114531764 114536711

» show all

Reference

PMID:12391161

Authors

Pak Y, Pham N, Rotin D

Title

Direct binding of the beta1 adrenergic receptor to the cyclic AMP-dependent guanine nucleotide exchange factor CNrasGEF leads to Ras activation.

Journal

Mol Cell Biol 22:7942-52 (2002)
DOI:10.1128/MCB.22.22.7942-7952.2002

Sequence

[hsa:153]

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