KEGG   ORTHOLOGY: K05132
Entry
K05132                      KO                                     

Name
IFNGR1, CD119
Definition
interferon gamma receptor 1
Pathway
ko04060  Cytokine-cytokine receptor interaction
ko04066  HIF-1 signaling pathway
ko04217  Necroptosis
ko04380  Osteoclast differentiation
ko04630  JAK-STAT signaling pathway
ko04650  Natural killer cell mediated cytotoxicity
ko04658  Th1 and Th2 cell differentiation
ko04659  Th17 cell differentiation
ko05140  Leishmaniasis
ko05142  Chagas disease
ko05145  Toxoplasmosis
ko05152  Tuberculosis
ko05164  Influenza A
ko05167  Kaposi sarcoma-associated herpesvirus infection
ko05168  Herpes simplex virus 1 infection
ko05200  Pathways in cancer
ko05235  PD-L1 expression and PD-1 checkpoint pathway in cancer
ko05321  Inflammatory bowel disease
Disease
H00089  IFN-gamma/IL-12 axis
H00342  Tuberculosis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04630 JAK-STAT signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04066 HIF-1 signaling pathway
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09133 Signaling molecules and interaction
   04060 Cytokine-cytokine receptor interaction
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09140 Cellular Processes
  09143 Cell growth and death
   04217 Necroptosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09150 Organismal Systems
  09151 Immune system
   04650 Natural killer cell mediated cytotoxicity
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04658 Th1 and Th2 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04659 Th17 cell differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09158 Development and regeneration
   04380 Osteoclast differentiation
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05235 PD-L1 expression and PD-1 checkpoint pathway in cancer
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09163 Immune disease
   05321 Inflammatory bowel disease
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09171 Infectious disease: bacterial
   05152 Tuberculosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09172 Infectious disease: viral
   05164 Influenza A
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05168 Herpes simplex virus 1 infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05167 Kaposi sarcoma-associated herpesvirus infection
    K05132  IFNGR1, CD119; interferon gamma receptor 1
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05140 Leishmaniasis
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   05142 Chagas disease
    K05132  IFNGR1, CD119; interferon gamma receptor 1
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04050 Cytokine receptors
    K05132  IFNGR1, CD119; interferon gamma receptor 1
   04090 CD molecules
    K05132  IFNGR1, CD119; interferon gamma receptor 1
Cytokine receptors [BR:ko04050]
 Interleukin receptor families
  IFN receptor family
   K05132  IFNGR1, CD119; interferon gamma receptor 1
CD molecules [BR:ko04090]
 Proteins
  K05132  CD119, IFNGR1; interferon gamma receptor 1
Other DBs
GO: 0004906
Genes
HSA: 3459(IFNGR1)
PTR: 747276(IFNGR1)
PPS: 100994342(IFNGR1)
GGO: 101150227(IFNGR1)
PON: 100171593(IFNGR1)
NLE: 100598615(IFNGR1)
MCC: 100423877(IFNGR1)
MCF: 101866179(IFNGR1)
CSAB: 103240303(IFNGR1)
RRO: 104675021(IFNGR1)
RBB: 108522967(IFNGR1)
CJC: 100386516(IFNGR1)
SBQ: 101054160(IFNGR1)
MMU: 15979(Ifngr1)
MCAL: 110303040(Ifngr1)
MPAH: 110338217(Ifngr1)
RNO: 116465(Ifngr1)
MUN: 110557641(Ifngr1)
CGE: 100772793(Ifngr1)
NGI: 103724895(Ifngr1)
HGL: 101709169(Ifngr1)
CCAN: 109697033(Ifngr1)
OCU: 100341787(IFNGR1)
TUP: 102475588(IFNGR1)
CFA: 100856077(IFNGR1)
VVP: 112919471(IFNGR1)
AML: 100473768(IFNGR1)
UMR: 103663370(IFNGR1)
UAH: 113259485(IFNGR1)
ORO: 101375882(IFNGR1)
ELK: 111147686
FCA: 101086811(IFNGR1)
PTG: 102952498(IFNGR1)
PPAD: 109249871(IFNGR1)
AJU: 106985768(IFNGR1)
BTA: 508619(IFNGR1)
BOM: 102275527(IFNGR1)
BIU: 109563984(IFNGR1)
BBUB: 102410135(IFNGR1)
CHX: 102182698(IFNGR1)
OAS: 101112907(IFNGR1)
SSC: 100152238(IFNGR1)
CFR: 102522759(IFNGR1)
CDK: 105092040(IFNGR1)
BACU: 103000886(IFNGR1)
LVE: 103082113(IFNGR1)
OOR: 101276054(IFNGR1)
DLE: 111166198(IFNGR1)
PCAD: 102977921(IFNGR1)
ECB: 100073195(IFNGR1)
EPZ: 103549045(IFNGR1)
EAI: 106837196(IFNGR1)
MYB: 102258073(IFNGR1)
MYD: 102761556(IFNGR1)
MNA: 107530983(IFNGR1)
HAI: 109376141 109385640(IFNGR1)
DRO: 112297082(IFNGR1)
PALE: 102888010(IFNGR1)
RAY: 107521298(IFNGR1)
MJV: 108410304(IFNGR1)
LAV: 100665172(IFNGR1)
TMU: 101345582
MDO: 100031565(IFNGR1)
SHR: 111720994(IFNGR1)
PCW: 110208928(IFNGR1)
OAA: 100078574(IFNGR1)
GGA: 421685(IFNGR1)
MGP: 100550637(IFNGR1)
CJO: 107311677(IFNGR1)
NMEL: 110395971(IFNGR1)
APLA: 101799854(IFNGR1)
ACYG: 106032518(IFNGR1)
TGU: 100222262(IFNGR1)
LSR: 110483306(IFNGR1)
SCAN: 103818469(IFNGR1)
GFR: 102034996(IFNGR1)
FAB: 101813223(IFNGR1)
PHI: 102104751(IFNGR1)
PMAJ: 107202224(IFNGR1)
CCAE: 111926795(IFNGR1)
CCW: 104689508(IFNGR1)
ETL: 114059495(IFNGR1)
FPG: 101911079(IFNGR1)
FCH: 102048414(IFNGR1)
CLV: 102085405(IFNGR1)
EGZ: 104131138(IFNGR1)
NNI: 104008886(IFNGR1)
ACUN: 113478368(IFNGR1)
PADL: 103912749(IFNGR1)
AAM: 106497894(IFNGR1)
ASN: 102374995(IFNGR1)
AMJ: 102566228(IFNGR1)
PSS: 102448524(IFNGR1)
CMY: 102936486(IFNGR1)
CPIC: 101945033(IFNGR1)
ACS: 103279436(ifngr1)
PVT: 110071491
PBI: 103056914(IFNGR1)
PMUR: 107294497(IFNGR1)
TSR: 106554510(IFNGR1)
PMUA: 114594178(IFNGR1)
GJA: 107121392(IFNGR1)
XLA: 108717881
XTR: 780275(ifngr1)
DRE: 100329124(ifngr1l) 794493(gdf10b)
IPU: 108263559(ifngr1)
PHYP: 113537513 113542090(ifngr1)
AMEX: 103034782
EEE: 113579645 113585524(ifngr1)
TRU: 105416329(ifngr1l)
LCO: 104931539(ifngr1l)
MZE: 101468425(ifngr1)
ONL: 100690512(ifngr1l)
OLA: 105357941
XCO: 114144226
PRET: 103476693
CVG: 107098124
NFU: 107375815
KMR: 108246304(ifngr1)
ALIM: 106531287
AOCE: 111583941
POV: 109630900
LCF: 108897373
SDU: 111235225(ifngr1)
SLAL: 111645304(ifngr1)
BPEC: 110157034
MALB: 109974821
OTW: 112224548 112265249(ifngr1)
ELS: 105021221(ifngr1l) 105021504
SFM: 108918633 108932840(ifngr1l)
PKI: 111837605(ifngr1) 111850737
LCM: 102362892(IFNGR1)
CMK: 103178319 103178320(ifngr1)
 » show all
Reference
PMID:2971451
  Authors
Aguet M, Dembic Z, Merlin G
  Title
Molecular cloning and expression of the human interferon-gamma receptor.
  Journal
Cell 55:273-80 (1988)
DOI:10.1016/0092-8674(88)90050-5
  Sequence
[hsa:3459]
Reference
  Authors
Donnelly RP, Sheikh F, Kotenko SV, Dickensheets H
  Title
The expanded family of class II cytokines that share the IL-10 receptor-2 (IL-10R2) chain.
  Journal
J Leukoc Biol 76:314-21 (2004)
DOI:10.1189/jlb.0204117

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