KEGG ORTHOLOGY: K05296

ORTHOLOGY: K05296

Entry

K05296                      KO

Symbol

E1.1.1.51

Name

3(or 17)beta-hydroxysteroid dehydrogenase [EC:1.1.1.51]

Pathway

map00984

Steroid degradation

map01120

Microbial metabolism in diverse environments

Reaction

R01836

testosterone:NAD+ 17-oxidoreductase

R01838

testosterone:NADP+ 17-oxidoreductase

R09956

epiandrosterone:NAD+ oxidoreductase

R09957

dehydroepiandrosterone:NAD+ oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K05296  E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.51  3(or 17)beta-hydroxysteroid dehydrogenase
     K05296  E1.1.1.51; 3(or 17)beta-hydroxysteroid dehydrogenase

Other DBs

GO:

0030283

Genes

RGL:	CS053_01735

PRE:	PCA10_43660

PFUW:

KF707C_11730 KF707C_11870

PPUU:

PputUW4_01679

PKC:

PKB_4320

PFZ:	AV641_10575

PPSY:

AOC04_07875

PSET:

THL1_4408

PSIL:

PMA3_11580

PKE:	DLD99_14670

PUM:	HGP31_20975

PPSH:

G5J76_13530

PLAL:

FXN65_05815 FXN65_21130

PAZE:

PTAE:

PCAV:

PPHN:

PIZ:	LAB08_R40780

PSHS:

PLAU:

SDEG:

HARR:

PPHA:

PALI:

PSYP:

SPL:

SHL:

CBER:

PRR:	AT705_22580

PVB:	J5X90_19405

PSYM:

J1N51_11265

SNAN:

I6N98_05660

ZAL:	AZF00_07095

OSG:	BST96_18245

MAGA:

Mag101_11180 Mag101_17580

HJA:	BST95_16580

HALC:

EY643_05560

KIM:	G3T16_08455

AFUS:

EYZ66_13070

PAQM:

E0F26_07275

ASIP:

AQUSIP_13610(cpnA_2)

LCJ:	NCTC11976_00397(phaB_1)

FCF:	FNFX1_1204

FPH:

FPT:

FPI:

FPM:

FPX:

FPZ:

FPJ:

FRT:	F7308_1194

FRF:	LO80_02190

FRX:	F7310_06325

FAD:	CDH04_04000

FMI:	F0R74_04375

FNN:	FSC774_04745

FSR:	KQR59_05790

OAI:	OLEAN_C32440

MSEC:

LN244_04840

MRZ:	KDW95_00835

BSAN:

CHH28_02370

NIK:	F5I99_08975

EMP:	EZMO1_1333(hsd)

SDF:	ACG33_10715 ACG33_10795

SOK:	D0B54_05265

SINI:

GT972_08470

FCE:	JN531_005460

RPJ:	N234_25135

RIN:	ACS15_4335 ACS15_4391

REH:	H16_B0642(h16_B0642) H16_B0649(h16_B0649)

CNC:	CNE_2c05880 CNE_2c05960 CNE_BB1p04020

CUH:	BJN34_26905 BJN34_30930

REU:	Reut_A1545 Reut_A1552

CTI:	RALTA_B0491

CBW:	RR42_s2341

COX:	E0W60_08155 E0W60_08190

CUK:	KB879_20650 KB879_20685 KB879_34810

CNAN:

A2G96_30315 A2G96_30320

BUR:	Bcep18194_B1514

BCT:

BCEP:

BPYR:

BCON:

BDF:	WI26_20980

BTEI:

BSTL:

BANN:

BARI:

BAEN:

BURK:

BFN:

PBRY:

PPAI:

PVE:	UC34_06900

CABA:

SBC2_48780

CTT:	CtCNB1_1764

CTES:

O987_11065

CRJ:	QMY55_09630

DIH:	G7047_09040 G7047_10950

MPT:

Mpe_A0884

METP:

C1M51_13620

SMIO:

CATMQ487_31550(fabG3)

DOE:	DENOEST_3109 DENOEST_3547(cpnA)

AZI:	AzCIB_1461

AZD:	CDA09_09700

THU:	AC731_008840

THAU:

C4PIVTH_4327

THK:	CCZ27_19355

THAG:

CKCBHOJB_02373

MRD:	Mrad2831_6397

MTEA:

DK419_00405

MIV:	C4E04_06100

RHZ:	RHPLAN_31970

METG:

HT051_00245

THD:	BHV28_12810

CAUL:

KCG34_11925 KCG34_11965

OAT:	OAN307_c19740

TGL:	HFZ77_15250

PLIA:

E4191_06175

DAA:	AKL17_3498

PSEB:

EOK75_03975

POZ:	I0K15_01515

NAR:	Saro_3532 Saro_3545

NPP:	PP1Y_AT13638 PP1Y_Mpl5490

NRE:	BES08_24625 BES08_24820

NOV:	TQ38_005795 TQ38_017245 TQ38_022035 TQ38_023650

NOT:	C7W88_19500 C7W88_19950

NGF:	FRF71_08380 FRF71_08390 FRF71_10150

NOG:	GKE62_04925 GKE62_06540 GKE62_06550

NOL:	NSDW_20670 NSDW_25180 NSDW_26920

SPHK:

SMAZ:

SPHQ:

SWI:

SPHD:

HY78_14230 HY78_22845 HY78_22850

SPHI:

TS85_08785

SPAN:

AWL63_11370 AWL63_24005

SKR:	BRX40_00695

SPHA:

D3Y57_18050

SJP:	SJA_C1-03930

SINB:

SIDU_16905

SYB:	TZ53_04155

SPMI:

K663_17776 K663_18116

SPHR:

BSY17_3924 BSY17_543

SHYD:

CJD35_00570 CJD35_06880

SCLO:

SCLO_1019010

SBAR:

H5V43_14105

SAMI:

SAMIE_1032770

SPPH:

KFK14_08000 KFK14_08870 KFK14_13450 KFK14_21620

CIJ:	WG74_05585

SPHG:

AZE99_02190 AZE99_02220 AZE99_02570 AZE99_05050

SFLA:

SPHFLASMR4Y_01233(benD) SPHFLASMR4Y_01334(benD) SPHFLASMR4Y_01377(benD) SPHFLASMR4Y_01860(benD) SPHFLASMR4Y_01932(benD) SPHFLASMR4Y_01938(benD)

SPHY:

CHN51_02990 CHN51_03345 CHN51_03375 CHN51_17560 CHN51_18065

BLAS:

BSY18_620

BFW:	B5J99_12325

SPHJ:

BSL82_07570 BSL82_07605 BSL82_14320

PARJ:

J4G78_04415 J4G78_06985 J4G78_13315 J4G78_13345 J4G78_16400 J4G78_17660

PHAO:

HF685_08370 HF685_13350 HF685_13380 HF685_15840

SMIC:

SmB9_08780 SmB9_08790

SAND:

H3309_10155 H3309_11070

ALH:	G6N82_09480 G6N82_09490

ARUE:

QQX03_02685 QQX03_02695

CMAN:

A9D14_16350 A9D14_16785

ELQ:	Ga0102493_111116 Ga0102493_111118 Ga0102493_112074

ERF:	FIU90_01575(fabG1) FIU90_01585

PNS:	A9D12_03500

ERYT:

KDC96_13830 KDC96_13840

PORL:

BG023_112375 BG023_11266 BG023_11268

PHZ:	CHX26_01065 CHX26_01075 CHX26_13090

POT:	E2E27_02035

PORC:

CBR61_00700 CBR61_00710 CBR61_13160

NTD:	EGO55_06220 EGO55_06680 EGO55_06825

CAEN:

K5X80_13060

GDI:

GDI2584

GDJ:

Gdia_0818

KNA:	B0W47_14495

KOI:	LV478_10085

SHUM:

STHU_19500

SVC:	STVA_17970

NCB:	C0V82_02450 C0V82_25770

RCE:

TXI:

THAC:

THAR:

SNEA:

GME:

MSD:	MYSTI_00848

MFB:	MFUL124B02_04805

MLAN:

JY572_22295

CCX:	COCOR_00721

CFUS:

CYFUS_005449

LPAR:

FAM21731_00863

OOE:

OEOE_0242

OEN:	DSM07_06745

OSI:	DLJ48_04325

VMA:	VAB18032_22275

CEP:	Cri9333_2499

PUV:

PUV_09390

» show all

Reference

PMID:193845

Authors

Schultz RM, Groman EV, Engel LL

Title

3(17)beta-Hydroxysteroid dehydrogenase of Pseudomonas testosteroni. A convenient purification and demonstration of multiple molecular forms.

Journal

J Biol Chem 252:3775-83 (1977)

Reference

PMID:20554032

Authors

Horinouchi M, Kurita T, Hayashi T, Kudo T

Title

Steroid degradation genes in Comamonas testosteroni TA441: Isolation of genes encoding a Delta4(5)-isomerase and 3alpha- and 3beta-dehydrogenases and evidence for a 100 kb steroid degradation gene hot spot.

Journal

J Steroid Biochem Mol Biol 122:253-63 (2010)
DOI:10.1016/j.jsbmb.2010.06.002

All links

Ontology (3)   
   KEGG BRITE (2)   
   GO (1)   
Pathway (4)   
   KEGG PATHWAY (4)   
Chemical reaction (7)   
   KEGG ENZYME (1)   
   KEGG REACTION (4)   
   KEGG RCLASS (2)   
Gene (1530)   
   KEGG GENES (277)   
   KEGG MGENES (1144)   
   RefGene (108)   
   OC (1)   
Literature (2)   
   PubMed (2)   
All databases (1546)   

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