KEGG ORTHOLOGY: K05334

ORTHOLOGY: K05334

Entry

K05334                      KO

Symbol

SLC6A19

Name

solute carrier family 6 (neurotransmitter transporter) member 19

Pathway

map04974

Protein digestion and absorption

map04978

Mineral absorption

Disease

H00843

Hartnup disorder

H00905

Iminoglycinuria

H01304

Hyperglycinuria

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    K05334  SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19
   04978 Mineral absorption
    K05334  SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05334  SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19
   04147 Exosome
    K05334  SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC6: Sodium- and chloride-dependent neurotransmitter transporter
   K05334  SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   K05334  SLC6A19; solute carrier family 6 (neurotransmitter transporter) member 19

Other DBs

GO:

0005330

TC:	2.A.22.6.3

Genes

HSA:	340024(SLC6A19)

PTR:	100612671(SLC6A19)

PPS:	134730361(SLC6A19)

GGO:	101128098(SLC6A19)

PON:	100173524(SLC6A19)

PPYG:

129037438(SLC6A19)

NLE:	100596167(SLC6A19)

HMH:	116456970(SLC6A19)

SSYN:

129464835(SLC6A19)

MCC:	100424683(SLC6A19)

MCF:	102140013(SLC6A19)

MTHB:

126957404

MNI:	105464571(SLC6A19)

CSAB:

103214924(SLC6A19)

CATY:

105600702(SLC6A19)

PANU:

101024082(SLC6A19)

TGE:	112626640(SLC6A19)

MLEU:

105528130(SLC6A19)

RRO:	104668702(SLC6A19)

RBB:	108513716(SLC6A19)

TFN:	117064698(SLC6A19)

PTEH:

111528339(SLC6A19)

CANG:

105519695(SLC6A19)

CJC:	100395048(SLC6A19)

SBQ:	101048016(SLC6A19)

CIMI:

108294171(SLC6A19)

ANAN:

105732953(SLC6A19)

CSYR:

103263031(SLC6A19)

MMUR:

105876454(SLC6A19)

LCAT:

123648003(SLC6A19)

PCOQ:

105825820(SLC6A19)

OGA:	100965053(SLC6A19)

MMU:	74338(Slc6a19)

MCAL:

110308202(Slc6a19)

MPAH:

110329107(Slc6a19)

RNO:	664630(Slc6a19)

MCOC:

116083180(Slc6a19)

ANU:	117723965(Slc6a19)

ASYL:

127666882(Slc6a19)

MUN:	110545361(Slc6a19)

CGE:	100762288(Slc6a19)

MAUA:

101831189(Slc6a19)

PROB:

127220864(Slc6a19)

PLEU:

114696101(Slc6a19)

MORG:

121433670(Slc6a19)

MFOT:

126503827

AAMP:

119810272(Slc6a19)

NGI:	103749671(Slc6a19)

HGL:	101706596(Slc6a19)

CPOC:

100715186(Slc6a19)

CCAN:

109698257(Slc6a19)

DORD:

105983856(Slc6a19)

DSP:	122121012(Slc6a19)

DMER:

138841451(Slc6a19)

PLOP:

125345090 125345091

NCAR:

124987074

MMMA:

107146358(Slc6a19)

ITI:	101956141(Slc6a19)

OCU:	100302437(SLC6A19)

OPI:	101530660(SLC6A19)

TUP:	102498528(SLC6A19)

GVR:	103582480 103604664(SLC6A19)

CFA:	100683912(SLC6A19)

CLUD:

112662765(SLC6A19)

VVP:	112935446(SLC6A19)

VLG:	121477528(SLC6A19)

NPO:	129498696(SLC6A19)

AML:	100479160(SLC6A19)

UMR:	103679265(SLC6A19)

UAH:	113260785(SLC6A19)

UAR:	123799100(SLC6A19)

ELK:

111153453

LLV:

125100623

MPUF:

101690694(SLC6A19)

MNP:	132028182(SLC6A19)

MLK:	131831535(SLC6A19)

NVS:	122896267(SLC6A19)

ORO:	101386033(SLC6A19)

EJU:	114198564(SLC6A19)

ZCA:	113929384(SLC6A19)

MLX:	118006194(SLC6A19)

NSU:	110577701(SLC6A19)

LWW:	102747715(SLC6A19)

FCA:	123380628(SLC6A19)

PYU:	121040751(SLC6A19)

PCOO:

112861714(SLC6A19)

PBG:	122495793(SLC6A19)

PVIV:

125159824(SLC6A19)

LRUF:

124522759

LGF:	123579297(SLC6A19)

AJU:

106985109

PTG:	102965266(SLC6A19)

PPAD:

109267685

PUC:

125934747

PLEZ:

122228598(SLC6A19)

HHV:	120235624(SLC6A19)

BTA:	100337416(SLC6A19)

BOM:	102268976(SLC6A19)

BIU:	109574754(SLC6A19)

BBUB:

102415755(SLC6A19)

BBIS:

105001014(SLC6A19)

CHX:	102188256(SLC6A19)

OAS:	114118762(SLC6A19)

BTAX:

128066146(SLC6A19)

CSUM:

138094523(SLC6A19)

ODA:	120879242(SLC6A19)

CCAD:

122454582(SLC6A19)

MREE:

136146633(SLC6A19)

OVR:	110136168(SLC6A19)

MBEZ:

129553082(SLC6A19)

SSC:	641346(SLC6A19)

CFR:	102509526(SLC6A19)

CBAI:

105081215(SLC6A19)

CDK:	105102194(SLC6A19)

VPC:	102538955(SLC6A19)

BACU:

103002801(SLC6A19)

BMUS:

118891751(SLC6A19)

LVE:	103088450(SLC6A19)

OOR:	125964060(SLC6A19)

LALB:

132518784(SLC6A19)

GMF:

115853241

DDP:

132422334

DLE:	111178484(SLC6A19)

PCAD:

102981180

PSIU:

116752227(SLC6A19)

PPHC:

136120659(SLC6A19)

NASI:

112390888(SLC6A19)

ECB:	100069470(SLC6A19)

EPZ:	103553583(SLC6A19)

EAI:	106835878(SLC6A19)

MYB:	102245862(SLC6A19)

MYD:	102769398(SLC6A19)

MMYO:

118657066(SLC6A19)

MLF:	102423517(SLC6A19)

MDT:	132233636(SLC6A19)

MYUM:

139008587(SLC6A19)

PKL:	118703498(SLC6A19)

EFUS:

103305121(SLC6A19)

MNA:	107536762(SLC6A19)

DRO:	112321106(SLC6A19)

SHON:

118998654(SLC6A19)

AJM:	119043405(SLC6A19)

PDIC:

114506003(SLC6A19)

PHAS:

123824991(SLC6A19)

MMF:	118642450(SLC6A19)

PPAM:

129074409(SLC6A19)

HAI:	109371678(SLC6A19)

RFQ:	117025333(SLC6A19)

PALE:

102891152(SLC6A19)

PGIG:

120586304(SLC6A19)

PVP:	105301318(SLC6A19)

RAY:	107499980(SLC6A19)

MJV:	108408616(SLC6A19)

TOD:	119260484(SLC6A19)

SARA:

101549249(SLC6A19)

SFUM:

130043018(SLC6A19)

SETR:

126000783(SLC6A19)

LAV:	100676875(SLC6A19)

TMU:

101342012

ETF:	101659571(SLC6A19)

DNM:	101411794(SLC6A19)

MDO:	100618267(SLC6A19)

GAS:	123238021(SLC6A19)

SHR:	100933103(SLC6A19)

AFZ:

127543588

PCW:	110201213(SLC6A19)

TVP:	118843061(SLC6A19)

PBRV:

138152504(SLC6A19)

MLAO:

141497353(SLC6A19)

OAA:	100074607(SLC6A19)

TACU:

119948860(SLC6A19)

GGA:	420971(SLC6A19)

PCOC:

116226540(SLC6A19)

MGP:	100546492(SLC6A19)

CJO:	107309458(SLC6A19)

TPAI:

128091508(SLC6A19)

LMUT:

125690693

NMEL:

110394863(SLC6A19)

APLA:

101791865(SLC6A19)

ACYG:

106045015

CATA:

118249971(SLC6A19)

AFUL:

116486299(SLC6A19)

TGU:	100223404(SLC6A19)

LSR:

110469749

SCAN:

103825943(SLC6A19)

PMOA:

120502987(SLC6A19)

OTC:	121337773(SLC6A19)

PRUF:

121358430(SLC6A19)

ATRC:

139604312

GFR:	102043780(SLC6A19)

FAB:	101819871(SLC6A19)

OMA:

130248828

PHI:	102108309(SLC6A19)

PMAJ:

107200980(SLC6A19)

CCAE:

111925331(SLC6A19)

CCW:	104685845(SLC6A19)

CBRC:

103619055(SLC6A19)

ACOE:

138104892

ETL:	114060992(SLC6A19)

ZAB:	102070344(SLC6A19)

ZLE:	135443234(SLC6A19)

ACHL:

103812228(SLC6A19)

SVG:	106855670(SLC6A19)

MMEA:

130582913(SLC6A19)

HRT:	120753202(SLC6A19)

SATI:

136366420(SLC6A19)

CCIC:

134048439(SLC6A19)

FPG:	101915935(SLC6A19)

FCH:

102047372

CCRI:

104158019(SLC6A19)

NNT:	104410262(SLC6A19)

SHAB:

115619801(SLC6A19)

ACUN:

113476610(SLC6A19)

TALA:

104359779(SLC6A19)

ACHC:

115340825(SLC6A19)

HALD:

104324810

HLE:	104841714(SLC6A19)

AGEN:

126051296

HHAR:

128142004(SLC6A19)

GCL:

127013044

CSTI:

104560267(SLC6A19)

LDI:

104340296

MNB:	103779999(SLC6A19)

DPUB:

104299418(SLC6A19)

PPUS:

135179010

AVIT:

104276255(SLC6A19)

BRHI:

104491771

EGZ:	104128508(SLC6A19)

NNI:	104013408(SLC6A19)

PCRI:

104028805(SLC6A19)

PCAO:

104042640(SLC6A19)

PADL:

103922328(SLC6A19)

AFOR:

103899691(SLC6A19)

FGA:	104083685(SLC6A19)

GSTE:

104257823(SLC6A19)

CBOY:

140646968

CLV:	102092964(SLC6A19)

CNIC:

135985131(SLC6A19)

MUI:	104544567(SLC6A19)

PGUU:

104468496(SLC6A19)

PLET:

104625769(SLC6A19)

EHS:

104512194

CMAC:

104478295(SLC6A19)

CUCA:

104061097(SLC6A19)

TEO:	104371719(SLC6A19)

BREG:

104635341(SLC6A19)

OHA:	104338156(SLC6A19)

ACAR:

104518103(SLC6A19)

CPEA:

104387714(SLC6A19)

CVF:	104286797(SLC6A19)

RTD:	128906236(SLC6A19)

CRID:

134511784(SLC6A19)

AAM:	106492854(SLC6A19)

AROW:

112971805(SLC6A19)

NPD:	112947537(SLC6A19)

TGT:	104580147(SLC6A19)

DNE:	112983039(SLC6A19)

SCAM:

104145274(SLC6A19)

ASN:	102383088(SLC6A19)

AMJ:	102563441(SLC6A19)

CPOO:

109313698(SLC6A19)

GGN:

109291960

PSS:	102447644(SLC6A19)

CMY:

102929740

CCAY:

125631975(SLC6A19)

DCC:	119851359(SLC6A19)

CPIC:

101946921(SLC6A19)

TST:	117872743(SLC6A19)

CABI:

116817009(SLC6A19)

MRV:	120397937(SLC6A19)

ACS:	100559327(slc6a19)

ASAO:

132774475

PVT:	110080905(SLC6A19)

PBI:	103056380(SLC6A19)

PMUR:

107292117(SLC6A19)

CTIG:

120301746(SLC6A19)

PGUT:

117662413(SLC6A19)

PCAE:

139313676

APRI:

131195161

PTEX:

113436551(SLC6A19)

NSS:	113415215(SLC6A19)

VKO:

123029736

PMUA:

114601046

PRAF:

128417951

ZVI:	118090404(SLC6A19)

HCG:

128325315

GJA:	107123974(SLC6A19)

STOW:

125443354

EMC:	129333364(SLC6A19)

XLA:	447481(slc6a19.S) 447504(slc6a19.L)

XTR:	100145739(slc6a19)

NPR:	108797280(SLC6A19)

RTEM:

120940469(SLC6A19)

ACAT:

141144711(SLC6A19)

BBUF:

121001511(SLC6A19)

BGAR:

122938530(SLC6A19)

DTC:	141099710(SLC6A19)

PWL:	138281813(SLC6A19)

MUO:	115474277(SLC6A19)

GSH:

117353636

DRE:	100334171(slc6a19a.2) 326030(slc6a19b) 553256(slc6a19a.1)

SRX:	107712286 107714768(slc6a19) 107714769 107743232

SANH:

107659347 107659348(slc6a19) 107662664 107685553 107694380

SGH:	107573763 107573764 107596751

CCAR:

109057086 109087061 109105822(slc6a19b) 109109590

CAUA:

113060199 113116289 113119705 113119706 113119745 113119746

CGIB:

127975429 127978669 127978670 128030054

PTET:

122335267 122360045(slc6a19b)

LROH:

127179031(slc6a19b) 127181567 127181698 127181699

GRF:	141289185 141289230 141289259 141343070(slc6a19b)

OMC:	131521545(slc6a19b) 131525505

PPRM:

120475274 120475276(slc6a19a.2) 120481246(slc6a19b)

RKG:	130070148(slc6a19b) 130092395 130092396(slc6a19a.1)

MAMB:

125244000(slc6a19b) 125276021 125276025 125276026

CIDE:

127497818 127501556 127501557

CERY:

137031453(slc6a19b) 137037376(slc6a19a.2) 137037377(slc6a19a.1)

MASI:

127425096 127425098 127452673 127454342

TROS:

130558373(slc6a19b) 130566865(slc6a19a.1) 130566869

TDW:	130415885(slc6a19a.1) 130415887(slc6a19a.2) 130433171(slc6a19b)

MANU:

129412677(slc6a19a.2) 129412678 129447800(slc6a19b)

PDAB:

135743538(slc6a19b) 135771289 135774014

IPU:	108270036(slc6a19b) 108274802(slc6a19a.2)

IFU:	128609097(slc6a19b) 128617982

PHYP:

113525260 113525261 113542400

SMEO:

124384406(slc6a19b) 124392165 124392167(slc6a19a.1)

TFD:	113633992 113644174(slc6a19b)

TVC:	132845988(slc6a19b) 132856853

CGAR:

128520892(slc6a19b) 128542875(slc6a19a.2) 128542882(slc6a19a.1)

NGRA:

132886001 132886747

TRN:	134310036(slc6a19b) 134318407 134333334(slc6a19a.1)

AMEX:

103023628(slc6a19b) 103025258 103025567

CMAO:

118812759(slc6a19a.1) 118812761(slc6a19a.2) 118825773(slc6a19b)

EEE:	113570598 113590694

CHAR:

105903643 105903644 105903646 105905464(slc6a19b)

SPIL:

134072461 134072470 134072734(slc6a19a.2) 134072735 134082172(slc6a19b)

TRU:	101078316 101078541 101078771

TFS:	130518129 130518130 130518131

TNG:	GSTEN00017549G001 GSTEN00017551G001

LCO:	104920432 104920433 104920447 104926700

NCC:	104946139 104962581 104965566

TBEN:

117477507 117477513 117477514 117478114 117478131 117480102(slc6a19b)

CGOB:

115015936 115015939 115015940 115015941 115016020 115021045

PGEO:

117454896 117455227 117455562 117455563 117460333(slc6a19b)

GACU:

117554033(slc6a19b) 117558683 117558694 117558695 117558697

EMAC:

134861217(slc6a19b) 134874617 134875521 134875522

ELY:	117263200 117263272 117263861 117263862 117265815(slc6a19b)

EFO:	125893957(slc6a19b) 125904704 125904705 125904706 125904707

PLEP:

121945387(slc6a19b) 121957624 121957681 121957797 121966531

SLUC:

116041220 116041332 116049380(slc6a19b) 116066847 116067012 116067025

ECRA:

117946785(slc6a19b) 117957024 117957025 117957026

ESP:	116691734 116701445

PFLV:

114557354 114567768 114568383 114568384

GAT:	120825919 120825949 120826976 120827063

PPUG:

119219698 119219700 119219722 119219730

AFB:	129096763 129096764 129097081 129097121 129109189(slc6a19b)

CLUM:

117738943 117738948 117738978 117739183 117739184 117739185 117745782(slc6a19b)

PSWI:

130194020 130194084 130212686 130213132

CANA:

137781139(slc6a19b) 137784494 137784499 137784511 137784530 137784536 137784545 137785030 137785031

CVE:	137872619 137872620 137872622 137872623 137872624 137891379(slc6a19b)

MSAM:

119906676 119906696 119906709 119908142

SCHU:

122864157 122864158 122864159 122864161

CUD:	121513773(slc6a19b) 121524015 121524016 121524032 121524068 121524096 121524117

SPUL:

138583744(slc6a19b) 138608381 138608400 138608404 138609433

LMIX:

132984095(slc6a19b) 132991633 132991634 132991636 132991650 132991651

ALAT:

119006579(slc6a19b) 119016498 119016499 119016500 119016501

ASTR:

137607250 137607272(slc6a19a.2) 137607761

MZE:	101471840 101472114 101472414

ONL:	100700835 100706073 102075498

OAU:	116320488 116320495 116320496

OLA:	101168797 101169218 101171425

OML:	112136246 112136299 112136303

CSAI:

133460462 133460464 133460465

XMA:	102235686 102235935

XCO:	114156361 114156363

XHE:	116731240 116731829

PRET:

103472109 103472110

PFOR:

103143307(slc6a19)

PLAI:

106958352 106958366

PMEI:

106923131 106923132

GAF:	122843921 122843922

PPRL:

129376332(slc6a19a.2) 129376406

CVG:	107092607 107092619

CTUL:

119799233 119799237

GMU:	124879484 124879795

NFU:	107383218 107383219

KMR:	108238697 108238756 108238765

ALIM:

106530870 106530871 106530873

NWH:	119425572 119426075

AOCE:

111576118 111576119 111576126 111576127 111588868(slc6a19b)

EJA:	138191619(slc6a19b) 138214423 138214506 138214730 138214731 138214732 138214733 138214734 138214808 138214896

BFRE:

138615023(slc6a19a.1) 138619218(slc6a19b)

MCEP:

125015687(slc6a19b) 125019395 125020028 125020035 125020627

CSEM:

103388402 103394655 103394657 103394683 103394684

POV:	109631588 109631634 109633026

SSEN:

122760636 122786555 122786556 122786609 122786610

SSOE:

131447139 131447349 131447770 131447862 131471301(slc6a19b)

HHIP:

117770746 117770747 117770750 117776696 117777198

HSP:	118113695 118114202 118124849 118124852 118125143

PPLT:

128449267 128461784 128461786 128462147

SMAU:

118311179 118311180 118311571

LCF:	108891114 108900388 108900389 108900390

SDU:	111223028 111223090 111223234 111238778

SLAL:

111673328 111673330 111673348

XGL:	120786301 120786318 120786394

HCQ:	109517680 109519188

SSCV:

125975532(slc6a19b) 125986885 125986886

SBIA:

133500399(slc6a19b) 133503867 133503875

PEE:	133395508 133396138 133401956

PTAO:

133470908 133471378 133479946(slc6a19b)

BPEC:

110167252 110167270 110167320 110167323 110171501

ENY:	140361800 140361801 140361803(slc6a19a.2) 140362311 140373712(slc6a19b)

MALB:

109951677 109951697

BSPL:

114843091(slc6a19b) 114865571 114865579 114865580

SJO:	128366812(slc6a19b) 128373803 128373804 128373807 128373987

SSCO:

133983412(slc6a19b) 133995943 133995944 133996050 133996051

GMH:	115535627 115535629 115535630 115545498

SASA:

100196793(slc6a19) 106589096 106606019 106606020

STRU:

115176286(slc6a19) 115177011 115184061 115186217 115186227

OTW:	112235538 112238959 112238960 112247786

OMY:	110489357 110496758 110514444 110516599 110519055 110520772

OGO:	124012042 124023032 124023188 124043132

ONE:	115121447 115126451

OKI:	109876377 109877093 109877218 109877219 109884896 109904372(slc6a19) 116369298

OKE:	118374725 118379757 118383636 127906087 127927548

OMM:	135532351 135549486 135551645

OCLA:

139372789 139391727 139401357 139402709 139405689 139405690

SALP:

112076086 112076282 112077975

SNH:	120021985 120036207 120042385 120047316 120047317

CCLU:

121538525 121555541 121555550 121585687 121585715 121585717 121585829

ELS:	105027727 105027728 105027738

OEP:	134006895 134007084(slc6a19a.2) 134007085 134023886(slc6a19b)

SFM:	108933301 108933302 108933415 108933416

PKI:	111846933(slc6a19) 111846934 111846942

AANG:

118233361 118233684 118233685

AROT:

135261529(slc6a19b) 135262156 135262157

CCOG:

133120042 133120043 133129859(slc6a19b)

LOC:	102689620(slc6a19)

PSPA:

121308273 121313964

ARUT:

117394494 117400070

PSEX:

120516062

LCM:	102361061(SLC6A19)

CMK:

103176218

RTP:	109912179(slc6a19a.1)

CPLA:

122564475

HOC:

132832354

LERI:

129710808

HAKA:

140713752(slc6a19a.1)

PMRN:

LRJ:

CIN:

BGT:

PMAX:

ATEN:

MCAZ:

MFOO:

Reference

PMID:15286788

Authors

Seow HF, Broer S, Broer A, Bailey CG, Potter SJ, Cavanaugh JA, Rasko JE

Title

Hartnup disorder is caused by mutations in the gene encoding the neutral amino acid transporter SLC6A19.

Journal

Nat Genet 36:1003-7 (2004)
DOI:10.1038/ng1406

Sequence

[hsa:340024]

Reference

PMID:18195088

Authors

Broer S

Title

Amino acid transport across mammalian intestinal and renal epithelia.

Journal

Physiol Rev 88:249-86 (2008)
DOI:10.1152/physrev.00018.2006

Reference

PMID:18400692

Authors

Broer S

Title

Apical transporters for neutral amino acids: physiology and pathophysiology.

Journal

Physiology (Bethesda) 23:95-103 (2008)
DOI:10.1152/physiol.00045.2007

All links

Ontology (2)   
   GO (1)   
   TC (1)   
Gene (838)   
   MGENES (418)   
   RefGene (415)   
   OC (5)   
All databases (840)   

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