KEGG ORTHOLOGY: K05653

ORTHOLOGY: K05653

Entry

K05653                      KO

Symbol

ABCB2, TAP1

Name

ATP-binding cassette, subfamily B (MDR/TAP), member 2 [EC:7.4.2.14]

Pathway

map02010

ABC transporters

map04145

Phagosome

map04612

Antigen processing and presentation

map05163

Human cytomegalovirus infection

map05168

Herpes simplex virus 1 infection

map05169

Epstein-Barr virus infection

map05170

Human immunodeficiency virus 1 infection

map05340

Primary immunodeficiency

Disease

H00984

MHC class I deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09150 Organismal Systems
  09151 Immune system
   04612 Antigen processing and presentation
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09160 Human Diseases
  09172 Infectious disease: viral
   05170 Human immunodeficiency virus 1 infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05168 Herpes simplex virus 1 infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05163 Human cytomegalovirus infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
   05169 Epstein-Barr virus infection
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
  09163 Immune disease
   05340 Primary immunodeficiency
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
Enzymes [BR:ko01000]
7. Translocases
  7.4  Catalysing the translocation of amino acids and peptides
   7.4.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.4.2.14  ABC-type antigen peptide transporter
     K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2
Transporters [BR:ko02000]
ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB2, 3, 8, 9, 10 subgroups
    K05653  ABCB2, TAP1; ATP-binding cassette, subfamily B (MDR/TAP), member 2

Other DBs

GO:

0015433

TC:

3.A.1.209

Genes

HSA:	6890(TAP1)

PTR:	471978(TAP1)

PPS:	100969222(TAP1)

GGO:	101135419(TAP1)

PON:	100444044(TAP1)

PPYG:

129038174(TAP1)

NLE:	100605253(TAP1)

HMH:	116460421(TAP1)

SSYN:

129472995(TAP1)

MCC:	717726(TAP1)

MCF:	102142346(TAP1)

MTHB:

126952703

MNI:	105474422(TAP1)

CSAB:

103221692(TAP1)

CATY:

105575008(TAP1)

PANU:

101014735(TAP1)

TGE:	112623507(TAP1)

MLEU:

105531118(TAP1)

RRO:	104666626(TAP1)

RBB:	108512976(TAP1)

TFN:	117087011(TAP1)

PTEH:

111528122(TAP1)

CANG:

105513792(TAP1)

CJC:	100407051(TAP1)

SBQ:	101050206(TAP1)

CIMI:

108300077(TAP1)

ANAN:

105704652(TAP1)

CSYR:

103271934(TAP1)

MMUR:

105886022(TAP1)

LCAT:

123631801(TAP1)

PCOQ:

105824378(TAP1)

OGA:	100966979(TAP1)

MMU:	21354(Tap1)

MCAL:

110312383(Tap1)

MPAH:

110335738(Tap1)

RNO:	24811(Tap1)

MCOC:

116074432(Tap1)

ANU:	117724686(Tap1)

MUN:	110543126(Tap1)

CGE:	100751458(Tap1)

MAUA:

106022611(Tap1)

PROB:

127224278(Tap1)

PLEU:

114686350(Tap1)

MORG:

121435237(Tap1)

MFOT:

126499463

AAMP:

119823090(Tap1)

NGI:	103748644(Tap1)

HGL:	101711399(Tap1)

CPOC:

100716745(Tap1)

CCAN:

109686707(Tap1)

DORD:

105999856(Tap1)

DSP:	122111481(Tap1)

PLOP:

125353513(Tap1)

NCAR:

124988990

MMMA:

107143776(Tap1)

OCU:

100349155

OPI:	101535942(TAP1)

TUP:	102488648(TAP1)

GVR:	103608009(TAP1)

CFA:	474866(TAP1)

CLUD:

112641381(TAP1)

VVP:	112913865(TAP1)

VLG:	121497333(TAP1)

NPO:	129513013(TAP1)

AML:	100464886(TAP1)

UMR:	103665513(TAP1)

UAH:	113243781(TAP1)

UAR:	123790943(TAP1)

ELK:

111152176

LLV:

125103272

MPUF:

101674199(TAP1)

MNP:	132017858(TAP1)

MLK:	131834271(TAP1)

NVS:	122911173(TAP1)

ORO:	101370146(TAP1)

EJU:	114222136(TAP1)

ZCA:	113926807(TAP1)

MLX:	118001395(TAP1)

NSU:	110575563(TAP1)

LWW:	102749278(TAP1)

FCA:	101083591(TAP1)

PYU:	121029258(TAP1)

PCOO:

112862344(TAP1)

PBG:	122489371(TAP1)

PVIV:

125165407(TAP1)

LRUF:

124528921

PTG:	102969103(TAP1)

PPAD:

109271409(TAP1)

PUC:

125938390

AJU:

106976125

HHV:	120238159(TAP1)

BTA:	524959(TAP1)

BOM:	102269065(TAP1)

BIU:	109577139(TAP1)

BBUB:

102391940(TAP1)

BBIS:

104994883(TAP1)

CHX:	102181173(TAP1)

OAS:	101115580(TAP1)

BTAX:

128056161(TAP1)

ODA:	120869861(TAP1)

CCAD:

122429562(TAP1)

MBEZ:

129543429(TAP1)

SSC:	733649(TAP1)

CFR:	102506212(TAP1)

CBAI:

105064241(TAP1)

CDK:	105101403(TAP1)

VPC:	102535891(TAP1)

BACU:

103011180(TAP1)

BMUS:

118904086(TAP1)

LVE:	103084615(TAP1)

OOR:	101289708(TAP1)

DLE:	111178660(TAP1)

PCAD:

102995173(TAP1)

PSIU:

116762103(TAP1)

NASI:

112413857(TAP1)

ECB:	100060845(TAP1)

EAI:	106834612(TAP1)

MYB:	102252020(TAP1)

MYD:	102761514(TAP1)

MMYO:

118679553(TAP1)

MLF:	102421555(TAP1)

MDT:	132237492(TAP1)

PKL:	118705649(TAP1)

EFUS:

129150467(TAP1)

MNA:	107542669(TAP1)

DRO:	112302332(TAP1)

SHON:

118991465(TAP1)

AJM:	119049933(TAP1)

PDIC:

114494744(TAP1)

PHAS:

123816513(TAP1)

MMF:	118621195(TAP1)

PPAM:

129067354(TAP1)

HAI:	109378146(TAP1)

RFQ:	117020460(TAP1)

PALE:

102893312(TAP1)

PGIG:

120597635(TAP1)

PVP:	105300966(TAP1)

RAY:	107511995(TAP1)

MJV:	108388306 108405341(TAP1)

TOD:	119252321(TAP1)

SARA:

101544289(TAP1)

SETR:

125995809(TAP1)

LAV:	100672952(TAP1)

TMU:

101341807

ETF:	101639668(TAP1)

DNM:	101433457(TAP1)

MDO:	100026750(TAP1)

GAS:	123245211(TAP1)

SHR:	116423203(TAP1)

AFZ:

127561620

PCW:	110199321 110199346(TAP1) 110199416

TVP:	118858132(TAP1) 118858245 118858253

OAA:	100088116(TAP1)

GGA:	427727(TAP1)

PCOC:

116236743(TAP1)

MGP:	100545399 104913621

CJO:	107321559(TAP1)

TPAI:

128074266(TAP1)

LMUT:

125686236(TAP1)

NMEL:

110406673(TAP1)

APLA:

101797680 119718657

ACYG:

106029502(TAP1)

CATA:

118260283(TAP1)

AFUL:

116500214(TAP1)

LSR:

PMOA:

PRUF:

FAB:

OMA:

PHI:

PMAJ:

CCW:

CBRC:

ETL:

ZLE:

HRT:

SATI:

SHAB:

115603459(TAP1)

ACUN:

113490724

TALA:

116963340(TAP1)

ACHC:

115338299(TAP1)

HLE:	104834904(TAP1)

AGEN:

BRHI:

EGZ:

AFOR:

CPEA:

104394208(TAP1)

RTD:

128901640

AAM:	106492644(TAP1)

CMY:	119567530(TAP1)

CPIC:

101952783

CABI:

116821656(TAP1) 116825565

MRV:	120394809 120394816(TAP1)

ACS:	100554917 100558440 100558977 103282465

ASAO:

132765336 132765811 132769673

PVT:	110071192(TAP1)

SUND:

121922961 121923358

PBI:	103063236(TAP1)

PMUR:

107296739(TAP1)

CTIG:

120317827(TAP1)

TSR:

106544595

PGUT:

117670039(TAP1)

APRI:

131191900(TAP1)

PTEX:

113451019(TAP1)

NSS:	113425983(TAP1)

VKO:	123023274(TAP1)

PMUA:

114592172 114592235(TAP1)

PRAF:

128409344(TAP1)

ZVI:	118080216(TAP1)

STOW:

125428884(TAP1)

XLA:	100329838(tap1.L)

XTR:	100494735(tap1) 108648266

NPR:	108788360(TAP1)

RTEM:

120914285(TAP1)

BBUF:

120977441(TAP1)

BGAR:

122919679(TAP1)

MUO:	115459444 115466179

GSH:	117349879(TAP1)

DRE:	100333043(tap1)

SRX:	107711531(tap1) 107715579

SANH:

107671442 107688213

SGH:	107592117 107592491(tap1)

CCAR:

109056322(tap1)

CAUA:

113059348 113101282 113115685

CGIB:

127975187 128029986

PTET:

122333975(tap1)

LROH:

127178906(tap1)

OMC:	131521848(tap1)

PPRM:

120491127(tap1)

RKG:	130078823(tap1)

MAMB:

125243603(tap1)

CIDE:

127496810

CERY:

137037898(tap1)

MASI:

127453367 127454128

TROS:

130557752(tap1)

TDW:	130433405(tap1)

MANU:

129448764(tap1)

IPU:

108256340

IFU:	128600046(tap1)

PHYP:

113532964

SMEO:

124375525(tap1)

TFD:	113649843(tap1)

TVC:	132840123(tap1)

TRN:	134300885(tap1)

AMEX:

103042617(tap1)

CMAO:

118798907(tap1)

EEE:	113578824(tap1)

CHAR:

105891881(tap1)

TRU:

101077331

TFS:	130532512(tap1)

TNG:	GSTEN00002627G001

LCO:

104928642

NCC:

104965249

TBEN:

117500552(tap1)

CGOB:

115021787

PGEO:

117460585(tap1)

GACU:

117543224(tap1)

EMAC:

134861502(tap1)

ELY:	117265256(tap1)

EFO:	125893418(tap1)

PLEP:

121945983(tap1)

SLUC:

116036106(tap1)

ECRA:

117945671(tap1)

ESP:

116690885

PFLV:

114557798

GAT:	120810165(tap1)

PPUG:

119197942(tap1)

AFB:	129109229(tap1)

CLUM:

117728065(tap1)

PSWI:

130212911(tap1)

MSAM:

119897095(tap1)

SCHU:

122881501(tap1)

CUD:	121513613(tap1)

ALAT:

119005680(tap1)

MZE:	101484302(tap1)

ONL:	100701175(tap1)

OAU:	116311333(tap1)

OLA:	101162709(tap1)

OML:	112136733(tap1)

CSAI:

133439275(tap1)

XMA:	102217160(tap1)

XCO:	114141733(tap1)

XHE:	116717209(tap1)

PRET:

103477852(tap1)

PFOR:

103146690(tap1)

PLAI:

106948877

PMEI:

106903295(tap1)

GAF:	122831242(tap1)

PPRL:

129370786(tap1)

CVG:

107082986

CTUL:

119777431(tap1)

GMU:	124866324(tap1)

NFU:

107379160

KMR:	108245991(tap1)

ALIM:

106523077(tap1)

NWH:	119409807(tap1)

AOCE:

111577918

MCEP:

125016940(tap1)

CSEM:

103388956

POV:

109647062

SSEN:

122774097(tap1)

HHIP:

117776256(tap1)

HSP:	118114170(tap1)

PPLT:

128449468(tap1)

SMAU:

118284721(tap1)

LCF:

108899590

SDU:	111222621(tap1)

SLAL:

111655648(tap1)

XGL:	120784568(tap1)

HCQ:	109521010(tap1)

SSCV:

125974814

SBIA:

133501431(tap1)

PEE:	133401619(tap1)

PTAO:

133479890(tap1)

BPEC:

110171064

MALB:

109965574(tap1)

BSPL:

114843532(tap1)

SJO:	128366653(tap1)

SASA:

100136585(tap1)

STRU:

115178246(tap1)

OTW:

112222999

OMY:	110487866(tap1)

OGO:	123997694(tap1)

ONE:	115114169 115141115(tap1)

OKI:	109902065 109903718

OKE:	118364394(tap1)

SALP:

111959198 111965141

SNH:	120031373 120048383

CCLU:

121559689 123484627

ELS:

105021865

SFM:	108926769 114909099

PKI:

111838464

AANG:

118225073(tap1)

PSPA:

121298813 121304295(tap1)

ARUT:

117433949 117962717

PSEX:

120539144(tap1)

LCM:	102361710(TAP1)

CMK:

103173390

HOC:	132832854(tap1)

LERI:

129694074 129694463

» show all

Reference

PMID:23340176

Authors

Xu M, Li L, Liu Z, Jiao Z, Xu P, Kong X, Huang H, Zhang Y

Title

ABCB2 (TAP1) as the downstream target of SHH signaling enhances pancreatic ductal adenocarcinoma drug resistance.

Journal

Cancer Lett 333:152-8 (2013)
DOI:10.1016/j.canlet.2013.01.002

Sequence

[hsa:6890]

Reference

PMID:2259383

Authors

Trowsdale J, Hanson I, Mockridge I, Beck S, Townsend A, Kelly A

Title

Sequences encoded in the class II region of the MHC related to the 'ABC' superfamily of transporters.

Journal

Nature 348:741-4 (1990)
DOI:10.1038/348741a0

Sequence

[hsa:6890]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   TC (1)   
Pathway (16)   
   KEGG PATHWAY (16)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (414)   
   KEGG GENES (374)   
   KEGG MGENES (20)   
   RefGene (14)   
   OC (6)   
Literature (2)   
   PubMed (2)   
All databases (439)   

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