KEGG   ORTHOLOGY: K05659
Entry
K05659                      KO                                     

Name
ABCB4
Definition
ATP-binding cassette, subfamily B (MDR/TAP), member 4 [EC:7.6.2.2]
Pathway
ko02010  ABC transporters
ko04976  Bile secretion
Disease
H00624  Progressive familial intrahepatic cholestasis
H01213  Gallbladder disease
H02193  Intrahepatic cholestasis of pregnancy
Brite
KEGG Orthology (KO) [BR:ko00001]
 09130 Environmental Information Processing
  09131 Membrane transport
   02010 ABC transporters
    K05659  ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4
 09150 Organismal Systems
  09154 Digestive system
   04976 Bile secretion
    K05659  ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K05659  ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4
Enzymes [BR:ko01000]
 7. Translocases
  7.6  Catalysing the translocation of other compounds
   7.6.2  Linked to the hydrolysis of a nucleoside triphosphate
    7.6.2.2  ABC-type xenobiotic transporter
     K05659  ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4
Transporters [BR:ko02000]
 ABC transporters, eukaryotic type
  ABCB (MDR/TAP) subfamily
   ABCB1, 4, 5 subgroups
    K05659  ABCB4; ATP-binding cassette, subfamily B (MDR/TAP), member 4
Other DBs
GO: 0008559
TC: 3.A.1.201
Genes
HSA: 5244(ABCB4)
PTR: 748364(ABCB4)
PPS: 100976274(ABCB4)
GGO: 101141298(ABCB4)
PON: 100455534
NLE: 100602308(ABCB4)
MCC: 706683(ABCB4)
MCF: 102115339(ABCB4)
CSAB: 103226609(ABCB4)
RRO: 104668032(ABCB4)
RBB: 108515081
CJC: 100398854(ABCB4)
SBQ: 101051647(ABCB4)
MMU: 18670(Abcb4)
MCAL: 110294486(Abcb4)
MPAH: 110316212
RNO: 24891(Abcb4)
MUN: 110555239(Abcb4)
CGE: 100682535(Abcb4)
NGI: 103725175(Abcb4)
HGL: 101717251(Abcb4)
CCAN: 109689161
OCU: 100354947(ABCB4)
TUP: 102478068(ABCB4)
CFA: 482284(ABCB4)
VVP: 112935084(ABCB4)
AML: 100475375(ABCB4)
UMR: 103658684(ABCB4)
UAH: 113259445(ABCB4)
ORO: 101368373(ABCB4)
ELK: 111155264
FCA: 109497287(ABCB4)
PTG: 102972907(ABCB4)
PPAD: 109263643(ABCB4)
AJU: 106987580(ABCB4)
BTA: 100336913(ABCB4)
BOM: 102280988(ABCB4)
BIU: 109557315
BBUB: 102391160(ABCB4)
CHX: 102171298(ABCB4)
OAS: 101122517(ABCB4)
SSC: 100144586(ABCB4)
CFR: 102513941
CDK: 105087357(ABCB4)
BACU: 103002339(ABCB4)
LVE: 103088229(ABCB4)
OOR: 101279182(ABCB4)
DLE: 111182170(ABCB4)
PCAD: 102983763(ABCB4)
ECB: 100147513(ABCB4)
MYB: 102246156(ABCB4)
MYD: 102755637(ABCB4)
MNA: 107541721(ABCB4)
HAI: 109371296(ABCB4)
DRO: 112302075(ABCB4)
PALE: 102880063
RAY: 107512456(ABCB4)
MJV: 108409276(ABCB4)
LAV: 100662269(ABCB4)
TMU: 101349036
MDO: 100462975(ABCB4)
SHR: 100914588
PCW: 110209191
OAA: 100077786(ABCB4)
GGA: 420534(ABCB1LA)
MGP: 100548646(ABCB1)
CJO: 107309017
NMEL: 110392993
APLA: 110352387
ACYG: 106039633(ABCB4)
CLV: 102095142
AAM: 106483501
ASN: 102387370
AMJ: 102558575(ABCB4)
 » show all
Reference
  Authors
Klaassen CD, Aleksunes LM
  Title
Xenobiotic, bile acid, and cholesterol transporters: function and regulation.
  Journal
Pharmacol Rev 62:1-96 (2010)
DOI:10.1124/pr.109.002014
Reference
PMID:3405218
  Authors
Gros P, Raymond M, Bell J, Housman D
  Title
Cloning and characterization of a second member of the mouse mdr gene family.
  Journal
Mol Cell Biol 8:2770-8 (1988)
DOI:10.1128/mcb.8.7.2770
  Sequence
[mmu:18670]

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