KEGG ORTHOLOGY: K06487

ORTHOLOGY: K06487

Entry

K06487                      KO

Symbol

ITGAV, CD51

Name

integrin alpha V

Pathway

map04145

Phagosome

map04148

Efferocytosis

map04151

PI3K-Akt signaling pathway

map04510

Focal adhesion

map04512

ECM-receptor interaction

map04514

Cell adhesion molecules

map04810

Regulation of actin cytoskeleton

map04820

Cytoskeleton in muscle cells

map04919

Thyroid hormone signaling pathway

map05163

Human cytomegalovirus infection

map05165

Human papillomavirus infection

map05200

Pathways in cancer

map05205

Proteoglycans in cancer

map05222

Small cell lung cancer

map05410

Hypertrophic cardiomyopathy

map05412

Arrhythmogenic right ventricular cardiomyopathy

map05414

Dilated cardiomyopathy

map05418

Fluid shear stress and atherosclerosis

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K06487  ITGAV, CD51; integrin alpha V
  09133 Signaling molecules and interaction
   04512 ECM-receptor interaction
    K06487  ITGAV, CD51; integrin alpha V
   04514 Cell adhesion molecules
    K06487  ITGAV, CD51; integrin alpha V
09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    K06487  ITGAV, CD51; integrin alpha V
   04148 Efferocytosis
    K06487  ITGAV, CD51; integrin alpha V
  09144 Cellular community - eukaryotes
   04510 Focal adhesion
    K06487  ITGAV, CD51; integrin alpha V
  09142 Cell motility
   04820 Cytoskeleton in muscle cells
    K06487  ITGAV, CD51; integrin alpha V
   04810 Regulation of actin cytoskeleton
    K06487  ITGAV, CD51; integrin alpha V
09150 Organismal Systems
  09152 Endocrine system
   04919 Thyroid hormone signaling pathway
    K06487  ITGAV, CD51; integrin alpha V
09160 Human Diseases
  09161 Cancer: overview
   05200 Pathways in cancer
    K06487  ITGAV, CD51; integrin alpha V
   05205 Proteoglycans in cancer
    K06487  ITGAV, CD51; integrin alpha V
  09162 Cancer: specific types
   05222 Small cell lung cancer
    K06487  ITGAV, CD51; integrin alpha V
  09172 Infectious disease: viral
   05163 Human cytomegalovirus infection
    K06487  ITGAV, CD51; integrin alpha V
   05165 Human papillomavirus infection
    K06487  ITGAV, CD51; integrin alpha V
  09166 Cardiovascular disease
   05418 Fluid shear stress and atherosclerosis
    K06487  ITGAV, CD51; integrin alpha V
   05410 Hypertrophic cardiomyopathy
    K06487  ITGAV, CD51; integrin alpha V
   05412 Arrhythmogenic right ventricular cardiomyopathy
    K06487  ITGAV, CD51; integrin alpha V
   05414 Dilated cardiomyopathy
    K06487  ITGAV, CD51; integrin alpha V
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04131 Membrane trafficking
    K06487  ITGAV, CD51; integrin alpha V
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K06487  ITGAV, CD51; integrin alpha V
   04515 Cell adhesion molecules
    K06487  ITGAV, CD51; integrin alpha V
   04090 CD molecules
    K06487  ITGAV, CD51; integrin alpha V
Membrane trafficking [BR:ko04131]
Endocytosis
  Phagocytosis
   Integrins (complement receptors)
    K06487  ITGAV, CD51; integrin alpha V
Exosome [BR:ko04147]
Exosomal proteins
  Exosomal proteins of haemopoietic cells  (B-cell, T-cell, DC-cell, reticulocyte, and mast cell)
   K06487  ITGAV, CD51; integrin alpha V
  Exosomal proteins of epithelial cells
   K06487  ITGAV, CD51; integrin alpha V
Cell adhesion molecules [BR:ko04515]
Integrins
  Integrin alpha subunits
   K06487  ITGAV, CD51; integrin alpha V
CD molecules [BR:ko04090]
Proteins
  K06487  CD51, ITGAV; integrin, alpha V

Genes

HSA:	3685(ITGAV)

PTR:	459807(ITGAV)

PPS:	100975589(ITGAV)

GGO:	101148851(ITGAV)

PON:	100451792(ITGAV)

PPYG:

129031423(ITGAV)

NLE:	100604485(ITGAV)

HMH:	116810565(ITGAV)

SSYN:

129488146(ITGAV)

MCC:	707756(ITGAV)

MCF:	102116249(ITGAV)

MTHB:

126933042

MNI:	105468297(ITGAV)

CSAB:

103217487(ITGAV)

CATY:

105579920(ITGAV)

PANU:

101017655(ITGAV)

TGE:	112635941(ITGAV)

MLEU:

105553894(ITGAV)

RRO:	104667754(ITGAV)

RBB:	108535417(ITGAV)

TFN:	117094753(ITGAV)

PTEH:

111542813(ITGAV)

CANG:

105507806(ITGAV)

CJC:	100389906(ITGAV)

SBQ:	101032614(ITGAV)

CIMI:

108315634(ITGAV)

ANAN:

105731940(ITGAV)

CSYR:

103268155(ITGAV)

MMUR:

105879310(ITGAV)

LCAT:

123643975(ITGAV)

PCOQ:

105825770(ITGAV)

OGA:	100945899(ITGAV)

MMU:	16410(Itgav)

MCAL:

110311058(Itgav)

MPAH:

110318229(Itgav)

RNO:	296456(Itgav)

MCOC:

116090387(Itgav)

ANU:	117702960(Itgav)

MUN:	110559159(Itgav)

CGE:	100752313(Itgav)

MAUA:

101826420(Itgav)

PROB:

127222344(Itgav)

PLEU:

114703598(Itgav)

MORG:

121439259(Itgav)

MFOT:

126487714

AAMP:

119818595(Itgav)

NGI:	103728788(Itgav)

HGL:	101717672(Itgav)

CPOC:

100728575(Itgav)

CCAN:

109686646(Itgav)

DORD:

105995249(Itgav)

DSP:	122114967(Itgav)

PLOP:

125350485(Itgav)

NCAR:

124979207

MMMA:

107138529(Itgav)

OCU:

100008956

OPI:	101535157(ITGAV)

TUP:	102469850(ITGAV)

GVR:	103604851(ITGAV) 103606818

CFA:	488437(ITGAV)

CLUD:

112668239(ITGAV)

VVP:	112931084(ITGAV)

VLG:	121501614(ITGAV)

NPO:	129498520(ITGAV)

AML:	100483894(ITGAV)

UMR:	103659655(ITGAV)

UAH:	113250684(ITGAV)

UAR:	123798116(ITGAV)

ELK:

111155043

LLV:	125094948 125095857

MPUF:

101681626(ITGAV) 101690880

MNP:	132013895(ITGAV)

MLK:	131826998(ITGAV)

NVS:	122902666(ITGAV)

ORO:	101368762(ITGAV)

EJU:	114223458(ITGAV)

ZCA:	113919409(ITGAV)

MLX:	118012237(ITGAV)

NSU:	110592349(ITGAV)

LWW:	102735999(ITGAV)

FCA:	101085820(ITGAV)

PYU:	121030799(ITGAV)

PCOO:

112848575(ITGAV)

PBG:	122481545(ITGAV)

PVIV:

125172290(ITGAV)

LRUF:

124515657

PTG:	102972745(ITGAV)

PPAD:

109274234(ITGAV)

PUC:

125911491

AJU:

106976526

HHV:	120241461(ITGAV)

BTA:	281875(ITGAV)

BOM:	102281111(ITGAV)

BIU:	109565743(ITGAV)

BBUB:

102406315(ITGAV)

BBIS:

105002887(ITGAV)

CHX:	102187813(ITGAV)

OAS:	443143(ITGAV)

BTAX:

128061467(ITGAV)

ODA:	120854008(ITGAV)

CCAD:

122453909(ITGAV)

MBEZ:

129538673(ITGAV)

SSC:	397285(ITGAV)

CFR:	102508062(ITGAV)

CBAI:

105072910(ITGAV)

CDK:	105098976(ITGAV)

VPC:	102538173(ITGAV)

BACU:

103000411(ITGAV)

BMUS:

118898185(ITGAV)

LVE:	103087072(ITGAV)

OOR:	101286638(ITGAV)

DLE:	111171639(ITGAV)

PCAD:

102980851(ITGAV)

PSIU:

116757071(ITGAV)

NASI:

112403267(ITGAV)

ECB:	100068706(ITGAV)

EPZ:	103557856(ITGAV)

EAI:	106827445(ITGAV)

MYB:	102260401(ITGAV)

MYD:	102763517(ITGAV)

MMYO:

118661050(ITGAV)

MLF:	102439153(ITGAV)

MDT:	132238032(ITGAV)

PKL:	118718755(ITGAV)

EFUS:

103290656(ITGAV)

MNA:	107536679(ITGAV)

DRO:	112305765(ITGAV)

SHON:

118985328(ITGAV)

AJM:	119042993(ITGAV)

PDIC:

114493963(ITGAV)

PHAS:

123820205(ITGAV)

MMF:	118625208(ITGAV)

PPAM:

129061828(ITGAV)

HAI:	109372713(ITGAV)

RFQ:	117025896(ITGAV)

PALE:

102895440(ITGAV)

PGIG:

120584269(ITGAV)

PVP:	105289673(ITGAV)

RAY:	107513835(ITGAV)

MJV:	108396573(ITGAV)

TOD:	119256010(ITGAV)

SARA:

101553309(ITGAV)

SETR:

126008895(ITGAV)

LAV:	100671252(ITGAV)

TMU:

101356496

ETF:	101643277(ITGAV)

DNM:	101438715(ITGAV)

MDO:	100028127(ITGAV)

GAS:	123242170(ITGAV)

SHR:	100929053(ITGAV)

AFZ:

127554490

PCW:	110201716(ITGAV)

TVP:	118836076(ITGAV)

OAA:	100085661(ITGAV)

GGA:	396420(ITGAV)

PCOC:

116235937(ITGAV)

MGP:	100541922(ITGAV)

CJO:	107316434(ITGAV)

TPAI:

128076982(ITGAV)

LMUT:

125697148(ITGAV)

NMEL:

110400462(ITGAV)

APLA:

101803022(ITGAV)

ACYG:

106034465(ITGAV)

CATA:

118259181(ITGAV)

AFUL:

116490600(ITGAV)

TGU:	100228982(ITGAV)

LSR:	110476177(ITGAV)

SCAN:

103814560(ITGAV)

PMOA:

120511498(ITGAV)

OTC:	121335292(ITGAV)

PRUF:

121364364(ITGAV)

GFR:	102036333(ITGAV)

FAB:	101808349(ITGAV)

OMA:	130255503(ITGAV)

PHI:	102112204(ITGAV)

PMAJ:

107207631(ITGAV)

CCAE:

111931704(ITGAV)

CCW:	104693720(ITGAV)

CBRC:

103612811(ITGAV)

ETL:	114059422(ITGAV)

ZAB:	102065707(ITGAV)

ZLE:	135450070(ITGAV)

ACHL:

103804211(ITGAV)

SVG:	106855922(ITGAV)

MMEA:

130583831(ITGAV)

HRT:	120754943(ITGAV)

SATI:

136363341(ITGAV)

FPG:	101920061(ITGAV)

FCH:	102060179(ITGAV)

CCRI:

104160863

NNT:	104400010(ITGAV)

SHAB:

115607829(ITGAV)

ACUN:

113482072(ITGAV)

TALA:

104359750(ITGAV)

ACHC:

115343263(ITGAV)

HALD:

104315023(ITGAV)

HLE:	104841535(ITGAV)

AGEN:

126042812

GCL:

127018161

CSTI:

104559452(ITGAV)

LDI:	104343952(ITGAV)

MNB:

103778532

DPUB:

104299256(ITGAV)

AVIT:

104273013(ITGAV)

BRHI:

104499253(ITGAV)

EGZ:	104130500(ITGAV)

NNI:	104015304(ITGAV)

PCRI:

104037829

PCAO:

104041070(ITGAV)

PADL:

103921674(ITGAV)

AFOR:

103902216(ITGAV)

FGA:	104083714(ITGAV)

GSTE:

104258876(ITGAV)

CLV:	102097696(ITGAV)

MUI:	104538623(ITGAV)

PGUU:

104467434

PLET:

104626445(ITGAV)

CMAC:

104473639(ITGAV)

CUCA:

104064547(ITGAV)

TEO:	104382098(ITGAV)

BREG:

104637064(ITGAV)

OHA:	104328416(ITGAV)

ACAR:

104520556

CPEA:

104386619(ITGAV)

CVF:	104291018(ITGAV)

RTD:	128912673(ITGAV)

AAM:	106499128(ITGAV)

AROW:

112960635(ITGAV)

NPD:	112942733(ITGAV)

TGT:	104572073(ITGAV)

DNE:	112989242(ITGAV)

SCAM:

104138619(ITGAV)

ASN:	102388058(ITGAV)

AMJ:	102569658(ITGAV)

CPOO:

109322812(ITGAV)

GGN:	109301633(ITGAV)

PSS:	102458254(ITGAV)

CMY:	102941818(ITGAV)

CCAY:

125644808(ITGAV)

DCC:	119863804(ITGAV)

CPIC:

101943422(ITGAV)

TST:	117884657(ITGAV)

CABI:

116831350(ITGAV)

MRV:	120374664(ITGAV)

ACS:	100567819(itgav)

ASAO:

132768155(ITGAV)

PVT:	110089997(ITGAV)

SUND:

121929473(ITGAV)

PBI:	103060270(ITGAV)

PMUR:

107297042(ITGAV)

CTIG:

120310958(ITGAV)

TSR:	106552079(ITGAV)

PGUT:

117672416(ITGAV)

APRI:

131201343(ITGAV)

PTEX:

113434019(ITGAV)

NSS:	113412421(ITGAV)

VKO:	123030840(ITGAV)

PMUA:

114606136(ITGAV)

PRAF:

128423745(ITGAV)

ZVI:	118093773(ITGAV)

HCG:	128334765(ITGAV)

GJA:	107121779(ITGAV)

STOW:

125426725(ITGAV)

EMC:	129323943(ITGAV)

XLA:	397997(itgav.L)

XTR:	100144691(itgav)

NPR:	108794469(ITGAV)

RTEM:

120913140(ITGAV)

BBUF:

120977161

BGAR:

122946190(ITGAV)

MUO:	115474688(ITGAV)

GSH:	117361075(ITGAV)

DRE:	100151255(itgav)

SRX:	107749889(itgav) 107752904

SANH:

107663834 107672211

SGH:	107560459(itgav) 107562103

CCAR:

109076847

CAUA:

113053588 113108748

CGIB:

127964455 128019659

PTET:

122351168(itgav)

LROH:

127170570(itgav)

OMC:	131546705(itgav)

PPRM:

120466799(itgav)

RKG:	130076678(itgav)

MAMB:

125270057(itgav)

CIDE:

127518234

CERY:

137035338(itgav)

MASI:

127447179 127447863

TROS:

130555555(itgav)

TDW:	130427235(itgav)

MANU:

129451593(itgav)

IPU:

108266447

IFU:	128608428(itgav)

PHYP:

113525923

SMEO:

124382563(itgav)

TFD:	113643410(itgav)

TVC:	132850507(itgav)

TRN:	134324414(itgav)

AMEX:

103023542(itgav)

CMAO:

118812176(itgav)

EEE:	113588804(itgav)

CHAR:

105901367 105905947(itgav)

TRU:	101079631(itgav)

TFS:

130527191

TNG:	GSTEN00035882G001

LCO:	104935588(itgav)

TBEN:

117498264(itgav)

EMAC:

134866975(itgav)

ELY:	117251214(itgav)

EFO:	125899784(itgav)

SLUC:

116046614(itgav)

PFLV:

114563523(itgav)

GAT:	120833776(itgav)

PPUG:

119228731(itgav)

AFB:	129104281(itgav)

CLUM:

117750141

PSWI:

130203063(itgav)

MSAM:

119903768(itgav) 119918606

SCHU:

122885133(itgav)

CUD:	121522710(itgav)

ALAT:

119025556(itgav)

MZE:	101477896(itgav)

ONL:	100697617(itgav)

OAU:	116312449(itgav)

OLA:	101174307(itgav)

OML:	112154815(itgav)

CSAI:

133445829(itgav)

XMA:	102223753(itgav)

XCO:	114147719(itgav)

XHE:	116722503(itgav)

PRET:

103460203(itgav)

PFOR:

103156471(itgav)

PLAI:

106959330(itgav)

PMEI:

106929168(itgav)

GAF:	122839798(itgav)

PPRL:

129361461 129379190

CVG:

107098331

CTUL:

119790193(itgav)

GMU:	124870788(itgav)

NFU:

107389602

KMR:	108247800(itgav)

ALIM:

106525498

NWH:	119419410(itgav)

AOCE:

111568071(itgav)

MCEP:

125017427(itgav)

CSEM:

103392367(itgav)

POV:	109640660(itgav)

HHIP:

117754490(itgav)

HSP:	118119933(itgav)

PPLT:

128455426(itgav)

SMAU:

118320435(itgav)

LCF:	108881975(itgav)

SDU:	111218062(itgav)

SLAL:

111659520(itgav)

XGL:	120801589(itgav)

HCQ:	109531168(itgav)

SSCV:

125973805

SBIA:

133502706(itgav)

PEE:	133410278(itgav)

PTAO:

133486352(itgav)

BPEC:

110162930(itgav)

MALB:

109971942(itgav)

BSPL:

114846901(itgav)

SJO:	128367491(itgav)

SASA:

106582518(itgav) 106586912

STRU:

115155445(itgav) 115160573

OTW:	112237229 112239256

OMY:	110501956 110522711

OGO:	124031914 124044295

OKI:	109875776 109881272

OKE:	118374512 118380878

SALP:

112075317(itgav)

SNH:

120064520

CCLU:

121536441 121555201

ELS:	105027294(itgav)

SFM:	108920329(itgav) 108930433

PKI:	111838588(itgav) 111843340

AANG:

118213773 118222898

LOC:	102684077(itgav)

PSPA:

121322193 121322994

ARUT:

117413994 117426837

PSEX:

120531892(itgav)

LCM:	102367090(ITGAV)

CMK:	103176518(itgav) 103183810

RTP:	109913127(itgav)

CPLA:

122551482(itgav)

HOC:	132817146(itgav)

LERI:

LPIC:

ADR:

OLG:

MSEX:

VCD:

ZCE:

HAW:

PGW:

NLU:

DPX:	DAPPUDRAFT_303480

PJA:	122254579 122262642 122267718

PCHN:

125025649 125033322

HAME:

121858639

PCLA:

123746350 123768368 123768370 123768434

PTRU:

123501455

ESN:	126985619 126985831

HAZT:

LSM:

PPOI:

DSV:

RSAN:

TUT:

HRO:	HELRODRAFT_168030

PVUL:

DPOL:

LJP:

ADF:

PDAM:

SPIS:

HSY:	130621913 130622608

AQU:

100636987

» show all

Reference

PMID:2443500

Authors

Suzuki S, Argraves WS, Arai H, Languino LR, Pierschbacher MD, Ruoslahti E

Title

Amino acid sequence of the vitronectin receptor alpha subunit and comparative expression of adhesion receptor mRNAs.

Journal

J Biol Chem 262:14080-5 (1987)

Sequence

[hsa:3685]

Reference

PMID:20615244

Authors

Lyle C, McCormick F

Title

Integrin alphavbeta5 is a primary receptor for adenovirus in CAR-negative cells.

Journal

Virol J 7:148 (2010)
DOI:10.1186/1743-422X-7-148

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