KEGG ORTHOLOGY: K07518

ORTHOLOGY: K07518

Entry

K07518                      KO

Symbol

E3.1.1.22

Name

hydroxybutyrate-dimer hydrolase [EC:3.1.1.22]

Pathway

map00650

Butanoate metabolism

map01100

Metabolic pathways

Reaction

R00048

(R)-3-((R)-3-hydroxybutanoyloxy)-butanoate hydroxybutanoylhydrolase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00650 Butanoate metabolism
    K07518  E3.1.1.22; hydroxybutyrate-dimer hydrolase
Enzymes [BR:ko01000]
3. Hydrolases
  3.1  Acting on ester bonds
   3.1.1  Carboxylic-ester hydrolases
    3.1.1.22  hydroxybutyrate-dimer hydrolase
     K07518  E3.1.1.22; hydroxybutyrate-dimer hydrolase

Other DBs

GO:

0047989

Genes

SACZ:

AOT14_27150(phaZ2)

STEK:

AXG53_12210

STEM:

CLM74_11365

SINC:

DAIF1_22070(phaZ2)

SLAB:

AB9L18_09805

PSUW:

WQ53_01110

PMEX:

H4W19_06590

PJP:	LAG73_05285

PDD:	MNQ95_00070

PWI:	MWN52_08145

PSSE:

OY559_12510

LAB:	LA76x_2936

LAQ:	GLA29479_253

LCP:	LC55x_2386

LGU:	LG3211_2850

LEZ:

GLE_2861

LEM:

LEN_2170

LYT:	DWG18_05225

LSOL:

GOY17_07345

LAUX:

LA521A_14020

LYA:	RDV84_18110

LSY:	H8L67_01180

LARE:

HIV01_003335

LHX:	LYSHEL_24960

LYW:	H2514_07755

LCAS:

LYSCAS_24960

LCIC:

INQ41_08100

LAVI:

INQ42_07560

LYJ:	FKV23_06985

LMB:	C9I47_1386

LSF:	I8J32_004215

LSX:	H8B22_06795

LUE:	DCD74_03510

LUS:	E5843_14540

LUG:	FPZ22_12945

LFX:	LU699_14210

LUJ:	BGP89_10410

THES:

FHQ07_01745

THEH:

G7079_08455

TCN:	H9L16_13615

TBV:	H9L17_01415

THEX:

ICG51_000315

XBC:	ELE36_11710

FSG:	LQ771_09545

FED:	LQ772_10790

RHD:	R2APBS1_1536

RTH:	LRK53_09410

DJI:	CH75_12505

DJA:	HY57_16195

DTX:	ATSB10_02030

DYE:	EO087_05065

DCS:	ISN74_06025

DTL:	H8F01_02275

DTA:	DYST_01345

DYG:	DYGSA30_21850

DKO:

I596_14

LRZ:	BJI69_15720

LPY:	FIV34_08110

LFL:	IM816_07040

LAEG:

L2Y94_08435

LAEO:

L2Y97_08800

LAES:

L2Y96_08940

XBA:	C7S18_17910

RBD:

ALSL_1632

TAMN:

N4264_09320

VNA:	PN96_21190

VEJ:	VEJY3_20446

VID:	DBX26_15995

PLUL:

FOB45_02940 FOB45_03300

MAQ:

Maqu_0083

MHC:

MARHY0070

MAD:

HP15_3792

MSR:	AU15_04470

MARI:

MARA:

MALL:

MSHE:

MANP:

MSAN:

MNK:	RE428_01600

MMEE:

NLK58_12735

MAMM:

ABNF92_10435

MRX:	MspRI1_04300

MACA:

MFLI:

SAGA:

SLIO:

TIG:

BLEP:

AFY:	BW247_08890

WMA:	WM2015_2321

GAI:	IMCC3135_14790

HAK:	KO116_03014

TWAN:

HUF19_16675

NCU:	F0U83_07895

PLEI:

Q9312_01210

GAP:	GAPWK_0910

GAQ:	RAM11_09005

FPP:	FPB0191_00792

ORB:	IPMB12_05785

OMO:	RHO11_03630

OSV:	RHO12_00795

IFL:	C1H71_19490

RSO:

RSc1334

RSE:

F504_1366

RPU:	CDC45_06875

RNC:	GO999_09735

RSC:	RCFBP_20092(phaY)

RSL:	RPSI07_2033(phaY)

RSN:	RSPO_c02022

RSM:	CMR15_20545(phaY)

RSY:	RSUY_17720

RSG:	JK151_10985

RPI:

Rpic_1209

RPF:	Rpic12D_1270

RPJ:	N234_13100

RMN:	TK49_10820

RIN:	ACS15_2033(phaZ2)

RWE:	KOL96_14215

REH:	H16_A2251(phaY1)

CNC:	CNE_1c21560(phaZ2)

CUH:	BJN34_11485

REU:	Reut_A1981

RME:	Rmet_1960(phaY)

CTI:	RALTA_A1796(phaY1)

CBW:	RR42_m2523

CGD:

CR3_1108

CCUP:

BKK81_25520

CUP:	BKK80_30880

CUU:	BKK79_21770

CPAU:

EHF44_12800

COX:	E0W60_20730

CCAM:

M5D45_09180

CCAX:

KZ686_12605

CUK:	KB879_23160(phaZ2)

CNAN:

CUPR:

CUPP:

BMA:

BMV:	BMASAVP1_A0886

BML:	BMA10229_A2720

BMN:	BMA10247_1890

BMAZ:

BM44_1320(phaZ2)

BMAL:

DM55_2423(phaZ2)

BMAE:

DM78_2599(phaZ2)

BMAQ:

DM76_2408(phaZ2)

BMAI:

DM57_820

BMAF:

DM51_1690(phaZ2)

BMAB:

BM45_882

BPS:

BPSL2716

BPM:	BURPS1710b_3200

BPL:	BURPS1106A_3184

BPD:	BURPS668_3147

BPR:	GBP346_A3326

BPSE:

BDL_2730(phaZ2)

BPSM:

BBQ_596(phaZ2)

BPSU:

BBN_724(phaZ2)

BPSD:

BBX_1129(phaZ2)

BPZ:	BP1026B_I0599

BPQ:	BPC006_I3225

BPK:	BBK_2217(phaZ2)

BPSH:

DR55_1803(phaZ2)

BPSA:

BBU_2848(phaZ2)

BPSO:

X996_1444(phaZ2)

BUT:	X994_3443(phaZ2)

BTE:

BTH_I1420

BTQ:	BTQ_2512(phaZ2)

BTJ:	BTJ_3182(phaZ2)

BTZ:	BTL_1113(phaZ2)

BTD:	BTI_884(phaZ2)

BTV:	BTHA_1205(phaZ2)

BTHE:

BTN_275(phaZ2)

BTHM:

BTRA_1321(phaZ2)

BTHA:

DR62_441

BTHL:

BG87_1310(phaZ2)

BOK:	DM82_2381(phaZ2)

BOC:	BG90_2352(phaZ2)

BUU:	WS70_13845

BSAV:

WS86_04685

BHG:	I6G56_16255

BUD:	AQ610_04300

BVI:	Bcep1808_0779

BVE:	AK36_27(phaZ2)

BUR:	Bcep18194_A3932

BCM:	Bcenmc03_0812

BCH:	Bcen2424_0840

BCJ:

BCAL3165

BCEN:

DM39_651(phaZ2)

BCEW:

DM40_1505(phaZ2)

BCEO:

I35_0697

BAM:

Bamb_0719

BAC:	BamMC406_0736

BMJ:	BMULJ_00694

BMU:

Bmul_2544

BMK:	DM80_844(phaZ2)

BMUL:

NP80_855(phaZ2)

BCT:

GEM_2689

BCED:

DM42_990(phaZ2)

BCEP:

APZ15_07845

BDL:	AK34_2333(phaZ2)

BPYR:

ABD05_09815

BCON:

NL30_11590

BUB:	BW23_897(phaZ2)

BDF:	WI26_03700

BLAT:

BTEI:

BSEM:

BPSL:

BMEC:

BSTG:

BSTL:

BANN:

BARI:

BAEN:

BSER:

BUG:	BC1001_5213

BGF:	BC1003_4271

BYI:	BYI23_A021060

BUK:

MYA_0735

BUL:	BW21_979(phaZ2)

BUQ:	AC233_23960

BUM:	AXG89_02600

BUI:	AX768_12315

BURK:

BURT:

BURM:

BURF:

BXE:

BXB:	DR64_4554(phaZ2)

BPH:

Bphy_5886

BGE:	BC1002_1604

BPX:	BUPH_05869

BPY:	Bphyt_5988

BCAI:

PARA:

PARB:

PTER:

PGP:	CUJ91_19600

PCJ:	CUJ87_30280

PTS:	CUJ90_26980

PGIS:

I6I06_19325

PACP:

FAZ97_29210

PEW:	KZJ38_05295

PDIO:

PDMSB3_0875.1

PSAA:

QEN71_26045

PKF:	RW095_11955

PHUN:

U0042_22325

PLAD:

PPGU16_25490

PAZZ:

PBP221_25850

CABA:

SBC2_29300(phaZ2)

BUO:	BRPE64_ACDS22210

CABK:

NK8_22250

BUE:	BRPE67_ACDS21760

TCAR:

U0034_19855

RFR:

Rfer_3022

RHY:	RD110_16910

RHOA:

HZ993_05315 HZ993_22215

POL:

Bpro_4732

PNA:

Pnap_3987

POS:	DT070_07415

POO:	F7R28_02005

ACK:	C380_16375

ACID:

ACIP:

ACIN:

ACIS:

ACIO:

ATEM:

ACIQ:

ACIV:

ASAH:

AAV:

AAA:

AMON:

DAC:

DEL:	DelCs14_4099

DTS:	BI380_11485

DHK:	BO996_12045

DLA:	I6G47_11420

CTT:	CtCNB1_1224

CODO:

LAD35_13220

CRJ:	QMY55_06640

ADN:	Alide_1916

ADK:	Alide2_2115

RTA:

Rta_15680

DPY:	BA022_02925

DIH:	G7047_06285

DAER:

H9K75_21805

DRG:	H9K76_14960

DLS:	P4826_06585

DIA:	Dtpsy_2060

SIMP:

MELM:

MELA:

RGE:

RBN:	RBXJA2T_04513

KIA:	G8A07_00975

PKT:	AT984_01170

SNN:	EWH46_05015

IDC:	LRM40_14315

ATER:

MW290_30000

LCH:

Lcho_4280

RGU:	A4W93_04170

JAG:	GJA_5269(phaZ2)

JAB:	VN23_05265

JAZ:	YQ44_26520

JAL:	BZG29_01515

JSV:	CNX70_01625

JAS:	FJQ89_18655

JLV:	G3257_01495

JAH:	JAB4_003230(phaZ2)

JRI:	P9875_01570

JAE:	OPV09_01595

MNR:	ACZ75_18960

MASY:

MENY:

MASZ:

MALI:

MUM:	FCL38_20965

MFLA:

GO485_16105

MPLI:

E1742_15900

TCT:	PX653_21420

PLUE:

EWM63_12800

DUG:	HH213_11310

DZO:	SR858_26175

RUG:	QC826_29215

EHB:	E7V67_027315

NOK:	FAY22_09810

XYK:	GT347_05230 GT347_24595

XYG:	R9X41_09855 R9X41_15550

PCAZ:

ACMDW7_15035

URU:	DSM104443_03848

UPL:	DSM104440_03398

AZO:

azo3634

AOA:

dqs_3779

AZA:

AZKH_3314

AZR:	CJ010_12290

AZQ:	G3580_07875

BEBA:

BWI17_07775

SHIN:

LHJ69_04695 LHJ69_05315

MET:

M446_0749

MOC:	BB934_26055 BB934_42265

BID:

Bind_3542

CAK:

Caul_3290

SKT:	IGS68_10710

SMUC:

JL100_016160

SROE:

JL101_014945

ECOG:

FIV45_06300

DMM:	dnm_083990

CFUS:

CYFUS_008232

SRC:	M271_06830

SMAL:

SSOI:

SBH:

SAUO:

SFEU:

SANT:

SCOA:

PLP:	Ple7327_3963

» show all

Reference

PMID:16233278

Authors

Saegusa H, Shiraki M, Saito T

Title

Cloning of an intracellular D(-)-3-hydroxybutyrate-oligomer hydrolase gene from Ralstonia eutropha H16 and identification of the active site serine residue by site-directed mutagenesis.

Journal

J Biosci Bioeng 94:106-12 (2002)
DOI:10.1263/jbb.94.106

Sequence

[reh:H16_A2251]

All links

Ontology (1)   
   GO (1)   
Gene (256)   
   MGENES (211)   
   RefGene (44)   
   OC (1)   
All databases (257)   

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