KEGG ORTHOLOGY: K12170

ORTHOLOGY: K12170

Entry

K12170                      KO

Symbol

RNF125

Name

E3 ubiquitin-protein ligase RNF125 [EC:2.3.2.27]

Pathway

map04622

RIG-I-like receptor signaling pathway

Disease

H01806

Tenorio syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    K12170  RNF125; E3 ubiquitin-protein ligase RNF125
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K12170  RNF125; E3 ubiquitin-protein ligase RNF125
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K12170  RNF125; E3 ubiquitin-protein ligase RNF125
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K12170  RNF125; E3 ubiquitin-protein ligase RNF125

Genes

HSA:	54941(RNF125)

PTR:	743809(RNF125)

PPS:	100973859(RNF125)

GGO:	101130622(RNF125)

PON:	100460705(RNF125)

PPYG:

129018652(RNF125)

NLE:	100588367(RNF125)

HMH:	116468631(RNF125)

SSYN:

129458863(RNF125)

MCC:	706726(RNF125)

MCF:	102122979(RNF125)

MTHB:

126941559

MNI:	105498269(RNF125)

CSAB:

103222569(RNF125)

CATY:

105592607(RNF125)

PANU:

100999670(RNF125)

TGE:	112611526(RNF125)

MLEU:

105535341(RNF125)

RRO:	104676061(RNF125)

RBB:	108519197(RNF125)

TFN:	117064006(RNF125)

PTEH:

111539740(RNF125)

CANG:

105513002(RNF125)

CJC:	100386104(RNF125)

SBQ:	101033024(RNF125)

CIMI:

108288233(RNF125)

ANAN:

105713472(RNF125)

CSYR:

103275976(RNF125)

MMUR:

105881095(RNF125)

LCAT:

123621676(RNF125)

PCOQ:

105820143(RNF125)

OGA:	100948379(RNF125)

MMU:	67664(Rnf125)

MCAL:

110284788(Rnf125)

MPAH:

110333452(Rnf125)

RNO:	361296(Rnf125)

MCOC:

116086890(Rnf125)

ANU:	117719937(Rnf125)

MUN:	110541501(Rnf125)

CGE:	100775067(Rnf125)

MAUA:

101836249(Rnf125)

PROB:

127234984(Rnf125)

PLEU:

114704991(Rnf125)

MORG:

121441881 121453561

MFOT:

126497090

AAMP:

119814977(Rnf125)

NGI:	103730582(Rnf125)

HGL:	101723725(Rnf125)

CPOC:

100715433(Rnf125)

CCAN:

109700576(Rnf125)

DORD:

105984622(Rnf125)

DSP:	122104315(Rnf125)

PLOP:

125364067(Rnf125)

NCAR:

124965831

MMMA:

107139553(Rnf125)

OCU:

100349404

OPI:	101521293(RNF125)

TUP:	102503377(RNF125)

GVR:	103588041(RNF125)

CFA:	490498(RNF125)

CLUD:

112647906(RNF125)

VVP:	112918805(RNF125)

VLG:	121495227(RNF125)

NPO:	129508966(RNF125)

AML:	100473812(RNF125)

UMR:	103663277(RNF125)

UAH:	113253322(RNF125)

UAR:	123782040(RNF125)

ELK:

111142639

LLV:

125082261

MPUF:

101693885(RNF125)

MNP:	132023553(RNF125)

MLK:	131811219(RNF125)

NVS:	122902948(RNF125)

ORO:	101383344(RNF125)

EJU:	114205000(RNF125)

ZCA:	113913142(RNF125)

MLX:	118004779(RNF125)

NSU:	110577057(RNF125)

LWW:	102732009(RNF125)

FCA:	101086183(RNF125)

PYU:	121033034(RNF125)

PCOO:

112868278(RNF125)

PBG:	122470681(RNF125)

PVIV:

125149495(RNF125)

LRUF:

124517581

PTG:	102948584(RNF125)

PPAD:

109276435(RNF125)

PUC:

125914279

AJU:

106984965

HHV:	120246833(RNF125)

BTA:	519541(RNF125)

BOM:	102268900(RNF125)

BIU:	109577894(RNF125)

BBUB:

102395830(RNF125)

BBIS:

104980321(RNF125)

CHX:	102187179(RNF125)

OAS:	101114324(RNF125)

BTAX:

128067566(RNF125)

ODA:	120881178(RNF125)

CCAD:

122425644(RNF125)

MBEZ:

129549698(RNF125)

SSC:	100517591(RNF125)

CFR:	102524108(RNF125)

CBAI:

105062523(RNF125)

CDK:	105086713(RNF125)

VPC:	102528363(RNF125)

BACU:

102997822(RNF125)

BMUS:

118879988(RNF125)

LVE:	103089350(RNF125)

OOR:	101288326(RNF125)

DLE:	111181506(RNF125)

PCAD:

102987593(RNF125)

PSIU:

116738818(RNF125)

NASI:

112408347(RNF125)

ECB:	100052335(RNF125)

EPZ:	103563489(RNF125)

EAI:	106833971(RNF125)

MYB:	102254436(RNF125)

MYD:	102761039(RNF125)

MMYO:

118663021(RNF125)

MLF:	102434401(RNF125)

MDT:	132240042(RNF125)

PKL:	118708422(RNF125)

EFUS:

103292183(RNF125)

MNA:	107524157(RNF125)

DRO:	112322801(RNF125)

SHON:

118977599(RNF125)

AJM:	119055548(RNF125)

PDIC:

114506788(RNF125)

PHAS:

123826229(RNF125)

MMF:	118619342(RNF125)

PPAM:

129078665(RNF125)

HAI:	109387903(RNF125)

RFQ:	117011790(RNF125)

PALE:

102889932(RNF125)

PGIG:

120587158(RNF125)

PVP:	105293324(RNF125)

RAY:	107521760(RNF125)

MJV:	108409154(RNF125)

TOD:	119243118(RNF125)

SARA:

101551021(RNF125)

SETR:

126003865(RNF125)

LAV:	100674497(RNF125)

TMU:

101351274

ETF:	101662235(RNF125)

DNM:	101423315(RNF125)

MDO:	100023988(RNF125)

GAS:	123239156(RNF125)

SHR:	100919305(RNF125)

AFZ:

127543914

PCW:	110212523(RNF125)

TVP:	118853202(RNF125)

OAA:	100084836(RNF125)

APLA:

101794545(RNF125)

AFUL:

116485638(RNF125)

ACHC:

115340812(RNF125)

HALD:

104313685(RNF125)

GCL:

127013436

DPUB:

104309118(RNF125)

EGZ:	104126871(RNF125)

NNI:	104019803(RNF125)

PCRI:

104034445(RNF125)

PCAO:

104040876(RNF125)

PADL:

103923197(RNF125)

AFOR:

103904247(RNF125)

FGA:	104069284(RNF125)

GSTE:

104255885(RNF125)

CLV:	110360010(RNF125)

MUI:	104546869(RNF125)

PGUU:

104463853(RNF125)

TEO:	104372180(RNF125)

BREG:

104634360(RNF125)

CPEA:

104396983(RNF125)

CVF:	104287296(RNF125)

AAM:	106494395(RNF125)

AROW:

112969481(RNF125)

DNE:	112994935(RNF125)

SCAM:

104149471(RNF125)

ASN:	102371695(RNF125)

AMJ:	102574346(RNF125)

CPOO:

109318315(RNF125)

GGN:	109304228(RNF125)

CMY:	102938903(RNF125)

CCAY:

125630982(RNF125)

DCC:	119852258(RNF125)

CPIC:

101931229(RNF125)

TST:	117871812(RNF125)

CABI:

116816214(RNF125)

MRV:	120397317(RNF125)

ACS:	100564260(rnf125)

ASAO:

132774794(RNF125)

PVT:	110077662(RNF125)

SUND:

121928463(RNF125)

PBI:	103060193(RNF125)

PMUR:

107292807(RNF125)

CTIG:

120303823(RNF125)

TSR:	106552103(RNF125)

PGUT:

117672744(RNF125)

APRI:

131194956

PTEX:

113435449(RNF125)

NSS:	113413832(RNF125)

VKO:	123020539(RNF125)

PMUA:

114600652(RNF125)

PRAF:

128417517(RNF125)

ZVI:	118089954(RNF125)

HCG:	128323818(RNF125)

GJA:	107113252(RNF125)

STOW:

125438786(RNF125)

EMC:	129333944(RNF125)

XLA:	108695278(rnf125.S) 108719232(rnf125.L)

XTR:	100493643(rnf125)

NPR:	108786093(RNF125)

RTEM:

120940952(RNF125)

BBUF:

121001211(RNF125)

BGAR:

122938672

MUO:	115460352(RNF125)

GSH:	117355894(RNF125)

LCM:	102348597(RNF125)

CSCU:

111620530 111622665

CVS:	136980638 136987040 136990542

» show all

Reference

PMID:17990982

Authors

Giannini AL, Gao Y, Bijlmakers MJ

Title

T-cell regulator RNF125/TRAC-1 belongs to a novel family of ubiquitin ligases with zinc fingers and a ubiquitin-binding domain.

Journal

Biochem J 410:101-11 (2008)
DOI:10.1042/BJ20070995

Sequence

[hsa:54941]

Reference

PMID:15843525

Authors

Zhao H, Li CC, Pardo J, Chu PC, Liao CX, Huang J, Dong JG, Zhou X, Huang Q, Huang B, Bennett MK, Molineaux SM, Lu H, Daniel-Issakani S, Payan DG, Masuda ES

Title

A novel E3 ubiquitin ligase TRAC-1 positively regulates T cell activation.

Journal

J Immunol 174:5288-97 (2005)
DOI:10.4049/jimmunol.174.9.5288

Sequence

[hsa:54941]

All links

Ontology (3)   
   KEGG BRITE (3)   
Pathway (2)   
   KEGG PATHWAY (2)   
Disease (1)   
   KEGG DISEASE (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (388)   
   KEGG GENES (226)   
   KEGG MGENES (75)   
   RefGene (85)   
   OC (2)   
Literature (2)   
   PubMed (2)   
All databases (397)   

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