KEGG ORTHOLOGY: K12239

ORTHOLOGY: K12239

Entry

K12239                      KO

Symbol

pchE

Name

L-cysteine---[L-cysteinyl-carrier protein] ligase PchE [EC:6.2.1.69]

Pathway

map01053

Biosynthesis of siderophore group nonribosomal peptides

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01053 Biosynthesis of siderophore group nonribosomal peptides
    K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE
Enzymes [BR:ko01000]
6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.69  L-cysteine---[L-cysteinyl-carrier protein] ligase
     K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE
Polyketide biosynthesis proteins [BR:ko01008]
Nonribosomal peptide synthetase (NRPS)
  Nonlinear NRPS
   Pyochelin synthetase
    K12239  pchE; L-cysteine---[L-cysteinyl-carrier protein] ligase PchE

Other DBs

COG:

COG1020

Genes

PGE:	LG71_26195

PAE:	PA4226(pchE)

PAEV:

N297_4358

PAEI:

N296_4358

PAU:	PA14_09270(pchE)

PAP:	PSPA7_0874(pchE)

PAG:	PLES_07011(pchE)

PAF:	PAM18_0711(pchE)

PNC:	NCGM2_5471(pchE)

PAEB:

NCGM1900_0733(pchE)

PDK:	PADK2_03540

PSG:	G655_03575

PRP:	M062_22265

PAEP:

PAER:

PAEM:

PAEL:

PAES:

PAEU:

BN889_04700(pchE_1) BN889_04701(pchE_2)

PAEG:

PAEC:

PAEO:

SECH:

PFL:	PFL_3493(pchE)

PPRC:

PFLCHA0_c35340(irp2)

PPRO:

PPC_3647(pchE)

PVR:	PverR02_15520

PCZ:	PCL1606_27860

PSEM:

TO66_16990

PSOS:

POS17_3636(pchE)

PSEP:

PSNC:

SAJS:

MAER:

BPS:	BPSS0586(pchE)

BPM:	BURPS1710b_A2150(pchE)

BPL:	BURPS1106A_A0787

BPD:	BURPS668_A0877

BPSE:

BPSM:

BPSU:

BPSD:

BPZ:	BP1026B_II0646(pchE)

BPQ:	BPC006_II0832

BPK:

BPSH:

BPSA:

BPSO:

BUT:

BTE:	BTH_II1828(pchE)

BTQ:

BTJ:

BTZ:

BTV:

BTHE:

BTHM:

BTHA:

BTHL:

BUR:	Bcep18194_B0672

BCM:	Bcenmc03_5289

BCH:	Bcen2424_4998

BCJ:	BCAM2230(pchE)

BCEO:

I35_6121(pchE)

BCED:

BCEP:

BSEM:

BSTL:

BARI:

BGP:	BGL_1c20580(pchE)

BPLA:

bpln_1g19100

ALI:	AZOLI_p20160(pchE)

RPAY:

THYR:

PFT:

AEQ:

NIE:	KV110_22880

SCYE:

R2B67_00090

SCB:

SCAB_1481

SRC:	M271_09930

SVE:

SVEN_0512

SGU:	SGLAU_04470(nrps1C) SGLAU_04650(nrps1E)

SPHW:

NFX46_19185

SPAD:

DVK44_09640

SDUR:

M4V62_41900

ASE:	ACPL_6158(nrps2C)

ACTS:

ACWT_6026

AOU:	ACTOB_004298

FCG:	LNP23_13860

AQR:	HN014_08650

» show all

Reference

PMID:10555976

Authors

Quadri LE, Keating TA, Patel HM, Walsh CT

Title

Assembly of the Pseudomonas aeruginosa nonribosomal peptide siderophore pyochelin: In vitro reconstitution of aryl-4, 2-bisthiazoline synthetase activity from PchD, PchE, and PchF.

Journal

Biochemistry 38:14941-54 (1999)
DOI:10.1021/bi991787c

Sequence

[pau:PA14_09270]

All links

Ontology (4)   
   KEGG BRITE (3)   
   COG (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (99)   
   KEGG GENES (91)   
   OC (8)   
Literature (1)   
   PubMed (1)   
All databases (107)   

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