KEGG ORTHOLOGY: K12858

ORTHOLOGY: K12858

Entry

K12858                      KO

Symbol

DDX23, PRP28

Name

ATP-dependent RNA helicase DDX23/PRP28 [EC:3.6.4.13]

Pathway

map03040

Spliceosome

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09121 Transcription
   03040 Spliceosome
    K12858  DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome
    K12858  DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28
Enzymes [BR:ko01000]
3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.13  RNA helicase
     K12858  DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28
Spliceosome [BR:ko03041]
Complex B
  U4/U6.U5 tri-snRNP components
   U5 snRNP specific factors
    K12858  DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28
Complex C
  U4/U6.U5 tri-snRNP components
   U5 SnRNP specific factors
    K12858  DDX23, PRP28; ATP-dependent RNA helicase DDX23/PRP28

Other DBs

COG:

COG0513

GO:

0003724

Genes

HSA:	9416(DDX23)

PTR:	451868(DDX23)

PPS:	100991680(DDX23)

GGO:	101147897(DDX23)

PON:	100172249(DDX23)

NLE:	100588301(DDX23)

MCC:	708185(DDX23)

MCF:	102118316(DDX23)

CSAB:

103238244(DDX23)

CATY:

105580401(DDX23)

PANU:

101010400(DDX23)

TGE:	112634096(DDX23)

RRO:	104679735(DDX23)

RBB:	108543897(DDX23)

TFN:	117090193(DDX23)

PTEH:

111532097 111542052(DDX23) 113220843

CJC:	100386786(DDX23)

SBQ:	101040836(DDX23)

CSYR:

103273460(DDX23)

MMUR:

105867787(DDX23)

OGA:	100941989(DDX23)

MMU:	74351(Ddx23)

MCAL:

110310725(Ddx23)

MPAH:

110334629(Ddx23)

RNO:	300208(Ddx23)

MCOC:

116079145(Ddx23)

MUN:	110547387(Ddx23)

CGE:	100767790(Ddx23)

PLEU:

114708528(Ddx23)

NGI:	103750560(Ddx23)

HGL:	101726476(Ddx23)

CPOC:

100730016(Ddx23)

CCAN:

109695486(Ddx23)

DORD:

105987542(Ddx23)

DSP:	122106275(Ddx23)

OCU:	100339552(DDX23)

OPI:	101527945(DDX23)

TUP:	102501838(DDX23)

CFA:	477624(DDX23)

VVP:	112921091(DDX23)

VLG:	121480011(DDX23)

AML:	100476672(DDX23)

UMR:	103675446(DDX23)

UAH:	113257669(DDX23)

UAR:	123794792(DDX23)

ELK:

111157938

MPUF:

101674713(DDX23)

ORO:	101372677(DDX23)

EJU:	114225787(DDX23)

ZCA:	113921961(DDX23)

MLX:	118008899(DDX23)

FCA:	101092374(DDX23)

PYU:	121038644(DDX23)

PBG:	122472337(DDX23)

PTG:	102950031(DDX23)

PPAD:

109249046(DDX23)

AJU:	106969295(DDX23)

HHV:	120223018(DDX23)

BTA:	537395(DDX23)

BOM:	102266279(DDX23)

BIU:	109559156(DDX23)

BBUB:

102406141(DDX23)

CHX:	102181753(DDX23)

OAS:	101104730(DDX23)

ODA:	120858164 120861290

CCAD:

122427247(DDX23) 122428357

SSC:	100737526(DDX23)

CFR:	102520412(DDX23)

CBAI:

105076189(DDX23)

CDK:	105103790(DDX23)

BACU:

103015481(DDX23)

LVE:	103076434(DDX23)

OOR:	101272021(DDX23)

DLE:	111174037(DDX23)

PCAD:

102985232(DDX23)

PSIU:

116760812(DDX23)

ECB:	100051439(DDX23)

EPZ:	103552194(DDX23)

EAI:	106836822(DDX23)

MYB:	102247592(DDX23)

MYD:	102764783(DDX23)

MMYO:

118650184(DDX23) 118652111 118678873

MLF:	102434620(DDX23)

MNA:	107528233(DDX23)

PKL:	118728620(DDX23)

HAI:	109393271(DDX23)

DRO:	112318416(DDX23)

SHON:

118976442(DDX23)

AJM:	119042191(DDX23)

PDIC:

114512788(DDX23)

PHAS:

123812959(DDX23)

MMF:	118624194(DDX23)

RFQ:	117029077(DDX23)

PALE:

102889747(DDX23)

PGIG:

120618212(DDX23)

PVP:	105297520(DDX23)

RAY:	107514226(DDX23)

MJV:	108383494(DDX23)

TOD:	119247876(DDX23)

SARA:

101558635(DDX23)

LAV:	100654666(DDX23)

TMU:

101350419

DNM:	101426735(DDX23)

MDO:	100032674(DDX23)

GAS:	123248562(DDX23)

SHR:	100925003(DDX23)

PCW:	110201483(DDX23)

OAA:	100077562(DDX23)

GGA:	100858001(DDX23)

PCOC:

116238647(DDX23)

MGP:	104915900(DDX23)

CJO:	107307085(DDX23)

NMEL:

110390472(DDX23)

ACYG:

106047713(DDX23)

AFUL:

116499911(DDX23)

TGU:	115491384(DDX23)

LSR:	110480388(DDX23)

SCAN:

103824611(DDX23)

PMOA:

120499478(DDX23)

OTC:	121334285(DDX23)

PRUF:

121356303(DDX23)

GFR:	102044996(DDX23)

FAB:	101811419(DDX23)

PHI:	102104184(DDX23)

PMAJ:

107198556(DDX23)

CCAE:

111940535(DDX23)

ETL:	114071079(DDX23)

ZAB:	102067940(DDX23)

FPG:	101914889(DDX23)

FCH:	102049976(DDX23)

CLV:	102088384(DDX23)

EGZ:	104124029(DDX23)

NNI:	104019885(DDX23)

TALA:

116962935(DDX23)

ACHC:

115351010(DDX23)

AAM:	106497505(DDX23)

AROW:

112960857(DDX23)

NPD:	112950332(DDX23)

DNE:	112996397(DDX23)

ASN:	102372343(DDX23)

AMJ:	102573795(DDX23)

CPOO:

109324467(DDX23)

PSS:	102449542(DDX23)

CMY:	102942623(DDX23)

CPIC:

101949703(DDX23)

TST:	117889269(DDX23)

CABI:

116827785(DDX23)

MRV:	120391348(DDX23)

ACS:	100563133(ddx23)

PVT:	110074913(DDX23)

SUND:

121922626(DDX23)

PBI:	103050770(DDX23)

PMUR:

107285673(DDX23)

TSR:	106551160(DDX23)

PGUT:

117662736(DDX23)

VKO:	123019209(DDX23)

PMUA:

114592962(DDX23)

ZVI:	118077458(DDX23)

GJA:	107120925(DDX23)

XLA:	108708543(ddx23.L) 108709812(ddx23.S)

XTR:	549967(ddx23)

NPR:	108791408(DDX23)

RTEM:

120929586(DDX23)

BBUF:

120995952(DDX23)

BGAR:

122931273(DDX23)

DRE:	334283(ddx23)

SRX:	107705733 107724177

SANH:

107693549(ddx23)

SGH:	107594085(ddx23) 107601339

CCAR:

109070505

CAUA:

113041068(ddx23) 113092997

IPU:	108276157(ddx23)

PHYP:

113530576(ddx23)

AMEX:

103037499(ddx23)

EEE:	113583113(ddx23)

TRU:	101070881(ddx23)

TNG:	GSTEN00037494G001

LCO:	104919642(ddx23)

NCC:	104952765(ddx23)

CGOB:

115010704(ddx23)

ELY:	117258906(ddx23)

PLEP:

121947477(ddx23)

SLUC:

116062171(ddx23)

ECRA:

117947967(ddx23)

PFLV:

114559346(ddx23)

GAT:	120829388(ddx23)

PPUG:

119223641(ddx23)

MSAM:

119905274(ddx23)

CUD:	121518050(ddx23)

MZE:	101483271(ddx23)

ONL:	100705024(ddx23)

OAU:	116310916(ddx23)

OLA:	101157453(ddx23)

OML:	112159688(ddx23)

XMA:	102233328(ddx23)

XCO:	114161754(ddx23)

XHE:	116726183(ddx23)

PRET:

103467622(ddx23)

PFOR:

103147811(ddx23)

PLAI:

106961432(ddx23)

PMEI:

106917489(ddx23)

GAF:	122839076(ddx23)

CVG:	107090279(ddx23)

CTUL:

119774119(ddx23)

NFU:	107391216(ddx23)

KMR:	108232155(ddx23)

ALIM:

106516750(ddx23)

NWH:	119416806(ddx23)

AOCE:

111570392(ddx23)

CSEM:

103385412(ddx23)

POV:	109635184(ddx23)

SSEN:

122777046(ddx23)

HHIP:

117764780(ddx23)

LCF:	108900205(ddx23)

SDU:	111217369(ddx23)

SLAL:

111671534(ddx23)

XGL:	120804230(ddx23)

HCQ:	109528547(ddx23)

BPEC:

110164761(ddx23)

MALB:

109966069(ddx23)

SASA:

106571944

OTW:	112215795(ddx23) 112221559

OMY:	110532030(ddx23)

OGO:	124031729(ddx23)

ONE:

115131917

SALP:

111966239(ddx23)

SNH:	120059481(ddx23)

ELS:	105026313(ddx23)

SFM:	108918185(ddx23)

PKI:	111837473(ddx23)

AANG:

118211195(ddx23)

LOC:	102693206(ddx23)

PSPA:

121309013(ddx23)

ARUT:

117401026 117967076

LCM:	102358300(DDX23)

CMK:	103173002(ddx23)

RTP:	109925973(ddx23)

BFO:

BBEL:

CIN:

SCLV:

SPU:	584867 754554

APLC:

110973540

SKO:

100372513

DME:	Dmel_CG10333(CG10333)

DER:

6549299

DSE:

6614563

DSI:	Dsimw501_GD24145(Dsim_GD24145)

DYA:	Dyak_GE13195

DAN:

6497876

DSR:

110187510

DPO:	Dpse_GA10248

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI14145

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

MDE:

SCAC:

LCQ:

AGA:	AgaP_AGAP007825

ACOZ:

AARA:

AAG:

AALB:

CQU:	CpipJ_CPIJ000951 CpipJ_CPIJ006204

CPII:

CNS:

AME:

ACER:

ALAB:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BPYO:

CCAL:

OBB:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CCIN:

TCA:

DPA:

SOY:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_202155

BANY:

PMAC:

PPOT:

PXU:

PRAP:

ZCE:

HAW:

TNL:

OFU:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

NLU:	111058589 120355994

PHU:	Phum_PHUM537610

FOC:

113218386

ZNE:

110832128

CSEC:

111861456 111866402 111867968 111871831

FCD:

110843929

DPX:	DAPPUDRAFT_303800

DMK:

PVM:

PJA:

HAME:

PCLA:

PTRU:

HAZT:

EAF:

ISC:	IscW_ISCW004825

DSV:	119434701 119440527

RSAN:

RMP:

VDE:

VJA:

TUT:

DPTE:

DFR:

CSCU:

PTEP:

SDM:

CEL:	CELE_F01F1.7(ddx-23)

CBR:

CBG_09074

BMY:	BM_BM3132(Bma-ddx-23)

LOA:	LOAG_18545

NAI:	NECAME_15135

TSP:

Tsp_11329

HRO:	HELRODRAFT_106716

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

MYI:

PMAX:

MMER:

123531299 123532169 123544531

OBI:

106868731

OSN:	115216631 115228057

LAK:

106166161

SMM:	Smp_093690.1

SHX:	MS3_0019687

OVI:	T265_03368

EGL:

NVE:

EPA:

ATEN:

ADF:	107330206 107351163

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:	100204486(ddx23)

TAD:	TRIADDRAFT_50105

AQU:

100639404

ATH:	AT1G28180 AT2G33730

ALY:	9315535 9326827

CRB:	17888679 17898026

CSAT:

104700071 104704282 104749495 104759469 104778918 104786193

EUS:	EUTSA_v10016306mg EUTSA_v10029441mg

BRP:	103857505 103865293

BNA:	106388042 106423074 106447161 106447192 111215087

BOE:	106328639 106342106

RSZ:	108805941 108846273 108847695 108854765

THJ:	104802643 104819001

CPAP:

110816404

CIT:	102628771 102629044

CIC:	CICLE_v10004480mg

PVY:

116145747

MINC:

123192872 123193196

TCC:

18602582

GRA:	105777104 105796429

GHI:	107903793 107914725 107927452 107934847

GAB:	108467239 108476114

DZI:

111279720

EGR:

104453573

GMX:	100792810 100799264

GSJ:	114392054 114420248

PVU:	PHAVU_003G088100g PHAVU_003G281500g

VRA:

VAR:

VUN:

CCAJ:

APRC:

MTR:	MTR_4g134170 MTR_6g005320

CAM:

101493350

LJA:	Lj4g3v0096270.1(Lj4g3v0096270.1)

ADU:

107465912

AIP:

107637019

AHF:	112706541 112722792

LANG:

109362512

FVE:	101295385 105350310

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103402142 103444644

PXB:

ZJU:

MNT:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

JCU:

HBR:

MESC:

POP:	7474827 7493486

PEU:	105133341 105135805

PALZ:

118044280 118051002

JRE:

109006707

QSU:	112002553 112007774 112009678 112021737 112035094

QLO:	115969979 115987025

TWL:	120000270 120007195

VVI:	100241918 100263263

VRI:

117922016

SLY:	101245423 101267079

SPEN:

107009542 107010997

SOT:	102584823 102588025

CANN:

107859647

NTA:	107769656 107772873

NSY:

104243810

NTO:	104103600 104116254

NAU:

INI:

ITR:

SIND:

OEU:	111369296 111403365

EGT:

105955761

SSPL:

121794539 121798419

HAN:

110865211

ECAD:

122578084 122578085 122590574

LSV:	111912356 111912357

CCAV:

112528269

DCR:	108202759 108204511

CSIN:

114257859 114318891

BVG:

104883288

SOE:

110803468

CQI:	110705947 110733666

NNU:

104591903

MING:

122079251

TSS:

122662076

PSOM:

113271422 113281305 113296776

NCOL:

116259031

OSA:

4333866

DOSA:

Os03t0708600-01(Os03g0708600)

OBR:

102708602

BDI:

100828951

ATS:	109760116 109780750

TDC:	119286916 119294795 119350927 119356427

TAES:

123069366 123087129 123090833 123095842 123115773 123134672 123134673 123161169

SBI:	8062925 8068309

ZMA:	100281521 100286176

SITA:

SVS:

PVIR:

PHAI:

PDA:	103701856 103721399

EGU:	105041295 105048742

MUS:

DCT:

PEQ:

AOF:

ATR:

SMO:	SELMODRAFT_11027 SELMODRAFT_149865 SELMODRAFT_153756 SELMODRAFT_165735

PPP:	112277816 112288624

CRE:	CHLRE_13g592150v5

VCN:	VOLCADRAFT_77867

CSL:	COCSUDRAFT_22967

CVR:	CHLNCDRAFT_56582

APRO:

F751_5556

OLU:	OSTLU_94867

OTA:	OT_ostta10g01950

BPG:	Bathy11g02000

MIS:	MICPUN_83331

MPP:	MICPUCDRAFT_13122

GSL:	Gasu_34230

CCP:	CHC_T00010142001

SCE:	YDR243C(PRP28)

AGO:	AGOS_AFR452C

ERC:

Ecym_1395

KLA:	KLLA0_C15433g

KMX:	KLMA_30514(PRP28)

LTH:	KLTH0E10890g

VPO:	Kpol_1007p10

ZRO:	ZYRO0A02948g

CGR:	CAGL0K11198g

NCS:	NCAS_0B02570(NCAS0B02570)

NDI:	NDAI_0C05120(NDAI0C05120)

TPF:	TPHA_0C01860(TPHA0C01860)

TBL:	TBLA_0D02800(TBLA0D02800)

TDL:	TDEL_0B01670(TDEL0B01670)

TGB:	HG536_0H01710

KAF:	KAFR_0E02810(KAFR0E02810)

ZMK:	HG535_0C01670

PPA:	PAS_chr2-2_0187

DHA:	DEHA2F10538g

PIC:	PICST_75833(PRP28)

PGU:	PGUG_01854

LEL:	LELG_00909

CAL:	CAALFM_C111300CA(CaO19.672)

CTP:	CTRG_04113

COT:	CORT_0A07180

CDU:	CD36_10600

CTEN:

CANTEDRAFT_110814

YLI:	YALI0F28391g

CLU:	CLUG_04075

CLUS:

A9F13_01g00330

CAUR:

CJI97_001836

SLB:	AWJ20_1301(PRP28)

PKZ:	C5L36_0A05070

BNN:	FOA43_001768

BBRX:

BRETT_004737

NCR:

NCU02803

NTE:	NEUTE1DRAFT133987(NEUTE1DRAFT_133987)

SMP:	SMAC_00622

PAN:	PODANSg10069

TTT:	THITE_2121904

MTM:	MYCTH_2295090

CTHR:

CTHT_0054430

MGR:

MGG_01583

TMN:	UCRPA7_2067

SSCK:

SPSK_06049

FGR:	FGSG_06849

FPU:	FPSE_11816

FVR:	FVEG_05137

FOX:	FOXG_01976

NHE:	NECHADRAFT_92729

TRE:	TRIREDRAFT_76481

TRR:	M419DRAFT_97090

MAW:

MAC_01015

MAJ:

MAA_05717

CMT:

CCM_06386

PLJ:	VFPFJ_05358

VAL:	VDBG_04918

VDA:	VDAG_04461

CFJ:	CFIO01_09868

ELA:	UCREL1_1247

PFY:	PFICI_01554

SSL:	SS1G_04405

BFU:	BCIN_01g05140

MBE:

MBM_08302

PSCO:

LY89DRAFT_714267

GLZ:	GLAREA_04495

ANI:

AN1634.2

AFM:	AFUA_4G09020

ACT:	ACLA_048380

NFI:	NFIA_107150

AOR:	AO090023000644

ANG:	ANI_1_1790184(An04g03920)

AFV:	AFLA_006989

ALUC:

AKAW2_51405S(PRP28)

ACHE:

ACHE_10628S(PRP28)

APUU:

APUU_21482A(PRP28)

PCS:	Pc18g03460

PDP:	PDIP_72560

TMF:	PMAA_056450

TRG:	TRUGW13939_00712

CIM:	CIMG_08335

CPW:	CPC735_061050

URE:	UREG_02508

PBL:	PAAG_03278

PBN:	PADG_03148

ABE:

ARB_00357

TVE:

TRV_04197

AJE:	HCAG_07085

BGH:	BDBG_00561

PNO:	SNOG_03936

PTE:

PTT_12655

BZE:	COCCADRAFT_9210

BSC:	COCSADRAFT_224467

BOR:	COCMIDRAFT_97942

AALT:

CC77DRAFT_849452

ZTR:	MYCGRDRAFT_60826

PFJ:	MYCFIDRAFT_177115

BCOM:

BAUCODRAFT_80305

NPA:	UCRNP2_2114

SPO:	SPCC63.11(prp28)

CNE:

CNA06640

CNB:

CNBA6450

CGI:	CGB_A7440W

TMS:	TREMEDRAFT_38519

TASA:

A1Q1_06890

TVS:	TRAVEDRAFT_164406

DSQ:	DICSQDRAFT_132148

PCO:	PHACADRAFT_173680

SHS:	STEHIDRAFT_74706

HIR:	HETIRDRAFT_457491

PSQ:	PUNSTDRAFT_105254

ADL:	AURDEDRAFT_133893

FME:	FOMMEDRAFT_132264

GTR:	GLOTRDRAFT_56935

LBC:	LACBIDRAFT_182393

MRR:	Moror_6451

CCI:	CC1G_11933

SCM:	SCHCODRAFT_256129

ABP:	AGABI1DRAFT104628(AGABI1DRAFT_104628)

ABV:	AGABI2DRAFT216556(AGABI2DRAFT_216556)

CPUT:

CONPUDRAFT_162325

SLA:	SERLADRAFT_417400

WSE:	WALSEDRAFT_61060

WIC:	J056_001413

UMA:	UMAG_10666

PFP:	PFL1_01270

MGL:

MGL_4141

MRT:

MRET_0871

MSYM:

MSY001_2941

PGR:	PGTG_12914

MLR:	MELLADRAFT_34708

MBR:	MONBRDRAFT_10827

SRE:	PTSG_08233

DDI:	DDB_G0277857(helB2)

DPP:	DICPUDRAFT_54136

DFA:	DFA_08018(helB2)

EHI:	EHI_021440(201.t00013)

EDI:	EDI_150900

EIV:	EIN_023770

ACAN:

ACA1_200160

PFA:	PF3D7_0518500

PFD:	PFDG_02199

PFH:	PFHG_00247

PREI:

PRSY57_0517600

PYO:	PY17X_1236700

PCB:	PCHAS_123390(PC000133.00.0)

PBE:	PBANKA_1233300

PVV:	PVVCY_1203420

PKN:	PKNH_1014700

PVX:	PVX_080320

PCY:	PCYB_102320

TAN:

TA07525

TPV:

TP04_0265

TOT:	TOT_040000636

BEQ:	BEWA_005300

BBO:	BBOV_II003280(18.m06276)

BMIC:

BmR1_04g08722

BBIG:

BBBOND_0203400

CPV:

cgd3_3690

CHO:	Chro.30417

TGO:	TGME49_298020

TET:	TTHERM_00991620

PTM:	GSPATT00021822001

SMIN:

v1.2.036809.t1(symbB.v1.2.036809.t1)

PTI:	PHATRDRAFT_12981

FCY:	FRACYDRAFT_184428

TPS:	THAPSDRAFT_13335

NGD:	NGA_0168600(DDX23)

AAF:	AURANDRAFT_10388

PIF:	PITG_05935

PSOJ:

PHYSODRAFT_361512

SPAR:

SPRG_08741

EHX:	EMIHUDRAFT_453778

GTT:	GUITHDRAFT_96054

NGR:	NAEGRDRAFT_34062

TVA:	TVAG_184440

» show all

Reference

PMID:18425142

Authors

Mathew R, Hartmuth K, Mohlmann S, Urlaub H, Ficner R, Luhrmann R

Title

Phosphorylation of human PRP28 by SRPK2 is required for integration of the U4/U6-U5 tri-snRNP into the spliceosome.

Journal

Nat Struct Mol Biol 15:435-43 (2008)
DOI:10.1038/nsmb.1415

Sequence

[hsa:9416]

All links

Ontology (5)   
   KEGG BRITE (3)   
   GO (1)   
   COG (1)   
Pathway (2)   
   KEGG PATHWAY (2)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Gene (6496)   
   KEGG GENES (816)   
   KEGG MGENES (784)   
   RefGene (4880)   
   OC (16)   
Literature (1)   
   PubMed (1)   
All databases (6505)   

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