KEGG ORTHOLOGY: K13175

ORTHOLOGY: K13175

Entry

K13175                      KO

Symbol

THOC6

Name

THO complex subunit 6

Pathway

map03013

Nucleocytoplasmic transport

Disease

H02253

Beaulieu-Boycott-Innes syndrome

Brite

KEGG Orthology (KO) [BR:ko00001]
09120 Genetic Information Processing
  09122 Translation
   03013 Nucleocytoplasmic transport
    K13175  THOC6; THO complex subunit 6
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K13175  THOC6; THO complex subunit 6
   03041 Spliceosome
    K13175  THOC6; THO complex subunit 6
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA surveillance and transport factors
   Transport factors
    TREX complex
     K13175  THOC6; THO complex subunit 6
Spliceosome [BR:ko03041]
Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   TREX complex
    K13175  THOC6; THO complex subunit 6

Other DBs

TC:

3.A.22.1

Genes

HSA:	79228(THOC6)

PTR:	107968770(THOC6)

PPS:	100994407(THOC6)

GGO:	101126740(THOC6)

PON:	100432073(THOC6)

PPYG:

129015509(THOC6)

NLE:	100587297(THOC6)

HMH:	116462238(THOC6)

SSYN:

129462167(THOC6)

MCC:	700217(THOC6)

MCF:	102141416(THOC6)

MTHB:

126944684

MNI:	105467890(THOC6)

CSAB:

103227108(THOC6)

CATY:

105572059(THOC6)

PANU:

101015703(THOC6)

TGE:	112614020(THOC6)

MLEU:

105541540(THOC6)

RRO:	104672316(THOC6)

RBB:	108523338(THOC6)

TFN:	117097758(THOC6)

PTEH:

111551747(THOC6)

CANG:

105517624(THOC6)

CJC:	100414440(THOC6)

SBQ:	101041001(THOC6)

CIMI:

108290975(THOC6)

ANAN:

105709801(THOC6)

CSYR:

103252042(THOC6)

MMUR:

105859736(THOC6)

LCAT:

123632286(THOC6)

PCOQ:

105813152(THOC6)

OGA:	100964053(THOC6)

MMU:	386612(Thoc6)

MCAL:

110283949(Thoc6)

MPAH:

110338054(Thoc6)

RNO:	79227(Thoc6)

MCOC:

116077674(Thoc6)

ANU:	117710582(Thoc6)

ASYL:

127694284(Thoc6)

MUN:	110545983(Thoc6)

CGE:	100767984(Thoc6)

MAUA:

101838611(Thoc6)

PROB:

127219594(Thoc6)

PLEU:

114680778(Thoc6)

MORG:

121463741(Thoc6)

MFOT:

126496843

AAMP:

119811897(Thoc6)

NGI:	103744121(Thoc6)

HGL:	101724280(Thoc6)

CPOC:

100736057(Thoc6)

CCAN:

109691708(Thoc6)

DORD:

105982243(Thoc6)

DSP:	122123846(Thoc6)

DMER:

138814609 138825473

PLOP:

125340564(Thoc6)

NCAR:

124970094

MMMA:

107146688(Thoc6)

ITI:	101956701(Thoc6)

OCU:

103345666

OPI:	101535363(THOC6)

TUP:	102499705(THOC6)

GVR:	103585360(THOC6)

CFA:	102151333 479871(THOC6)

CLUD:

112640490(THOC6) 112645631

VVP:	112909084(THOC6)

VLG:	121484664 121488089(THOC6)

NPO:	129499749 129519740(THOC6)

AML:	100476687(THOC6)

UMR:	103668509(THOC6)

UAH:	113245423(THOC6)

UAR:	123783540(THOC6)

ELK:

111156209

LLV:

125090614

MPUF:

101671809(THOC6)

MNP:	132026984(THOC6)

MLK:	131819476(THOC6)

NVS:	122896094(THOC6)

ORO:	101383201(THOC6)

EJU:	114215735(THOC6)

ZCA:	113933233(THOC6)

MLX:	118021746(THOC6)

NSU:	110588078(THOC6)

LWW:	102743111(THOC6)

FCA:	101099608(THOC6)

PYU:	121019636(THOC6)

PCOO:

112853184(THOC6)

PBG:	122471775(THOC6)

PVIV:

125154496(THOC6)

LRUF:

124517789

LGF:	123589256(THOC6)

AJU:

106978781

PTG:	102964704(THOC6)

PPAD:

109278204(THOC6)

PUC:

125927215

PLEZ:

122209666(THOC6)

HHV:	120241578(THOC6)

BTA:	100125940(THOC6)

BOM:	102285372(THOC6)

BIU:	109578646(THOC6)

BBUB:

102390541(THOC6)

BBIS:

104988882(THOC6)

CHX:	102188727(THOC6)

OAS:	101117811(THOC6)

BTAX:

128063270(THOC6)

CSUM:

138075610(THOC6)

ODA:	120873938(THOC6)

CCAD:

122433285(THOC6)

MREE:

136160458(THOC6)

OVR:	110148430(THOC6)

MBEZ:

129545298(THOC6)

SSC:	100626533(THOC6)

CFR:	102504648(THOC6)

CBAI:

105064821(THOC6)

CDK:	105099685(THOC6)

VPC:	102530716(THOC6)

BACU:

103004516(THOC6)

BMUS:

118881055(THOC6)

LVE:	103077450(THOC6)

OOR:	101287718(THOC6)

LALB:

132506511(THOC6)

GMF:	115848134(THOC6)

DDP:	132437944(THOC6)

DLE:	111185218(THOC6)

PCAD:

102996131(THOC6)

PSIU:

116739586(THOC6)

PPHC:

136134412(THOC6)

NASI:

112409549(THOC6)

ECB:	100068915(THOC6)

EPZ:	103551616(THOC6)

EAI:	106826044(THOC6)

MYB:	102242038(THOC6)

MYD:	102771113(THOC6)

MMYO:

118656851(THOC6)

MLF:	102434615(THOC6)

MDT:	132232978(THOC6) 132239985

MYUM:

139009138(THOC6)

PKL:	118703168(THOC6)

EFUS:

103286175(THOC6)

MNA:	107535844(THOC6)

DRO:	112298332(THOC6)

SHON:

118985088(THOC6)

AJM:	119056248(THOC6)

PDIC:

114495435(THOC6)

PHAS:

123807155(THOC6)

MMF:	118641737(THOC6)

PPAM:

129083628(THOC6)

HAI:	109377823(THOC6)

RFQ:	117019449(THOC6)

PALE:

102893165(THOC6)

PGIG:

120620298(THOC6)

PVP:	105303126(THOC6)

RAY:	107498773(THOC6)

MJV:	108394459(THOC6)

TOD:	119242002(THOC6)

SARA:

101537975(THOC6)

SFUM:

130042805(THOC6)

SETR:

126001260(THOC6)

LAV:	100666570(THOC6)

TMU:

101340895

ETF:	101638280(THOC6)

DNM:	101447101(THOC6)

MDO:	100017674(THOC6)

GAS:	123231572(THOC6)

SHR:	100928782(THOC6)

AFZ:

127542515

PCW:	110214521(THOC6)

TVP:	118831335(THOC6)

PBRV:

138176398(THOC6)

MLAO:

141495518(THOC6)

OAA:	100085741(THOC6)

TACU:

119935079(THOC6)

MGP:	104915907(THOC6)

CJO:	107307759(THOC6)

NMEL:

110391886(THOC6)

LSR:	110482389(THOC6)

ATRC:

139586412(THOC6)

ACOE:

138101188(THOC6)

ZLE:	135460563(THOC6)

SHAB:

115603109(THOC6)

CBOY:

140645698(THOC6)

CNIC:

136001220(THOC6)

CUCA:

128850077(THOC6)

ASN:	102368095(THOC6)

AMJ:	102573868(THOC6)

PSS:	102446335(THOC6)

CMY:	102933076(THOC6)

CCAY:

125638677(THOC6)

DCC:	119856752(THOC6)

CPIC:

101947748(THOC6)

CABI:

116831509(THOC6)

MRV:	120404130(THOC6)

ACS:	100556930(thoc6)

ASAO:

132777785(THOC6)

PVT:	110081829(THOC6)

SUND:

121932745(THOC6)

PBI:	103063273(THOC6)

PMUR:

107282717(THOC6) 107297566

CTIG:

120302193(THOC6)

TSR:	106543305(THOC6)

PGUT:

117666784(THOC6)

APRI:

131196935(THOC6)

PTEX:

113443685(THOC6)

NSS:	113421756(THOC6)

VKO:	123032122(THOC6)

PMUA:

114583673(THOC6)

PRAF:

128400889(THOC6)

ZVI:	118094343(THOC6)

HCG:	128329490(THOC6)

GJA:	107117623(THOC6)

STOW:

125444530(THOC6)

EMC:	129338291(THOC6)

XLA:	734907(thoc6.L)

XTR:	100498236(thoc6)

RTEM:

120942898(THOC6)

ACAT:

141148132(THOC6)

DTC:	141073151(THOC6)

PWL:	138304354(THOC6)

MUO:	115473797(THOC6)

GSH:	117360658(THOC6)

DRE:	100004014(thoc6)

SRX:	107729483 107730738

SANH:

107689651

SGH:	107554088 107583000

CCAR:

109058455(thoc6) 109058533

CAUA:

113045588(thoc6)

CGIB:

127949962

PTET:

122341734(thoc6)

LROH:

127163530(thoc6)

GRF:	141332828(thoc6)

OMC:	131537701(thoc6)

PPRM:

120489776(thoc6)

RKG:	130088479(thoc6)

MAMB:

125277434(thoc6)

CIDE:

127508024

CERY:

137017610(thoc6)

MASI:

127450466 127451807

TROS:

130561581(thoc6)

TDW:	130426267(thoc6)

MANU:

129436040(thoc6)

PDAB:

135767792(thoc6)

IPU:

108280484

IFU:	128604219(thoc6)

PHYP:

113525005(thoc6)

SMEO:

124396813(thoc6)

TFD:	113635376(thoc6)

TVC:	132860952(thoc6)

CGAR:

128544344(thoc6)

NGRA:

132868966(thoc6)

TRN:	134336194(thoc6)

AMEX:

103041053(thoc6)

CMAO:

118800537(thoc6)

EEE:	113580869(thoc6)

CHAR:

122130886(thoc6)

SPIL:

134076913(thoc6)

TRU:	101067999(thoc6)

TFS:	130515111(thoc6)

TNG:	GSTEN00012336G001

LCO:	104936297(thoc6)

TBEN:

117469320(thoc6)

PGEO:

117450786 117451077

GACU:

117558033(thoc6)

EMAC:

134878750(thoc6)

ELY:	117267958(thoc6)

EFO:	125879305(thoc6)

PLEP:

121956894(thoc6)

SLUC:

116050003(thoc6)

PFLV:

114569880(thoc6)

GAT:	120828063(thoc6)

PPUG:

119220919(thoc6)

AFB:	129098036(thoc6)

CLUM:

117734664(thoc6)

PSWI:

130188152(thoc6)

CANA:

137803468(thoc6)

CVE:	137884041(thoc6)

MSAM:

119895842(thoc6)

SCHU:

122868997(thoc6)

CUD:	121503575(thoc6)

SPUL:

138604205(thoc6)

LMIX:

132954292(thoc6)

ALAT:

119014835(thoc6)

ASTR:

137609825(thoc6)

MZE:	101468215(thoc6)

ONL:	100698469(thoc6)

OAU:	116323304(thoc6)

OLA:	101174081(thoc6)

OML:	112139419(thoc6)

CSAI:

133422667(thoc6)

XMA:	102219852(thoc6)

XCO:	114159683(thoc6)

XHE:	116736250(thoc6)

PRET:

103469456(thoc6)

PFOR:

103153069(thoc6)

PLAI:

106935028(thoc6)

PMEI:

106923657(thoc6)

GAF:	122821613(thoc6)

PPRL:

129373779(thoc6)

CVG:	107097657(thoc6)

CTUL:

119796859(thoc6)

GMU:	124862169 124864987

NFU:	107374411(thoc6)

KMR:	108251207(thoc6)

ALIM:

106528076(thoc6)

NWH:	119421819(thoc6)

AOCE:

111562936(thoc6)

EJA:	138207962(thoc6)

BFRE:

138631278(thoc6)

MCEP:

124997588(thoc6)

CSEM:

103393399(thoc6)

SSEN:

122785123(thoc6)

SSOE:

131475768(thoc6)

HHIP:

117766042(thoc6)

HSP:	118123285(thoc6)

PPLT:

128458919(thoc6)

SMAU:

118289158(thoc6)

LCF:

108891025

SDU:	111226849(thoc6)

SLAL:

111647391(thoc6) 111669177

XGL:	120788336(thoc6)

HCQ:	109513743(thoc6)

SSCV:

125983278(thoc6)

SBIA:

133514131(thoc6)

PEE:	133414635(thoc6)

PTAO:

133466453(thoc6)

BPEC:

110173649(thoc6)

ENY:	140358161(thoc6)

MALB:

109967553(thoc6)

BSPL:

114860746(thoc6)

SJO:	128378400(thoc6)

SSCO:

133998928(thoc6)

GMH:	115536139(thoc6)

SASA:

100196413(thoc6) 106600718

STRU:

115170793 115192132

OTW:	112252061(thoc6)

OMY:	110539095(thoc6)

OGO:	124000782(thoc6)

ONE:	115110010(thoc6)

OKI:	109893111(thoc6)

OKE:	118384276(thoc6)

OMM:	135555989(thoc6)

OCLA:

139420981

SALP:

111982027(thoc6)

SNH:	120033145(thoc6)

CCLU:

121550328 123491223

ELS:	105030389(thoc6)

OEP:	134035020(thoc6)

SFM:	108941667(thoc6)

PKI:	111836818(thoc6)

AANG:

118216746(thoc6)

AROT:

135244009(thoc6)

CCOG:

133115418(thoc6)

LOC:	102689362(thoc6)

PSPA:

121306800(thoc6)

PSEX:

120536596(thoc6)

LCM:	102356937(THOC6)

HOC:	132810751(thoc6)

HAKA:

140719395(thoc6)

PMRN:

116957777(THOC6)

LRJ:	133349088(THOC6)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG5632(thoc6)

DER:

6544592

DSI:	Dsimw501_GD12742(Dsim_GD12742)

DYA:	Dyak_GE20140

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11970

DAZ:

DNV:

DHE:

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:	101889538 131807175

SCAC:

106093553

LCQ:

111684758

LSQ:

119610047

CVJ:	135955058(thoc6)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ010587

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108726708(thoc6)

CCOA:

108777884

PBAR:

105432695

VEM:

105562822

COBS:

139113169(Thoc6)

TLN:	139818660(Thoc6)

HST:

105183820

DQU:

106744129

CFO:

105252515

FEX:	115239097 115245447

PMEC:

138941068 138941084(Thoc6)

LHU:	105667558(thoc6)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

CTYP:

141529585(Thoc6)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124223435(thoc6)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138125432(thoc6)

DPA:

109545509

ESIM:

136409837(thoc6)

EFOR:

136340831(thoc6)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209572

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137930482(thoc6)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

141427889(thoc6)

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

DVT:

BTAB:

CLEC:

HHAL:

106692521(thoc6)

NLU:	111064259 120354854

MQU:	128983492 128983504

PHU:	Phum_PHUM431960

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138693044(thoc6)

BROR:

134540334

IEL:

124158562

HAMR:

139691817(thoc6)

DPX:	DAPPUDRAFT_314241

DMK:

116919988

DPZ:

124313216

PVM:	113812815(thoc6)

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123761760(thoc6)

CQD:	128688750(thoc6)

PTRU:

123516640

ESN:

127009937

MNZ:	135214664 135214665

MRJ:	136854114(thoc6)

PORN:

139746104(thoc6)

HAZT:

108673630

EAF:

111695253

LSM:	121125631(thoc6)

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

GOE:

TUT:

DPTE:

DFR:

CVS:	136982598(thoc6)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

NAI:	NECAME_04887

BMY:	BM_BM10097(Bm10097)

LOA:	LOAG_12846

TSP:

Tsp_00318

HRO:	HELRODRAFT_181165

LGI:	LOTGIDRAFT_178363

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

LLON:

NVE:

EPA:	110237905 110248910

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_59146

AQU:	105314194 105315276

ATH:	AT2G19430(DWA1)

ALY:

9320059

CRB:

17891643

CSAT:

104701358 104747878 104748873 104767143

EUS:	EUTSA_v10022744mg

BRP:

103828298

BNA:	106352952 106390005

BOE:

RSZ:

THJ:

CPAP:

CIT:

GRA:

GHI:	107895807 107899953

GAB:

HSYR:

GMX:

VRA:

VAR:

TPRA:

PSAT:

VVO:	131629515 131629528

LJA:

130710171

LANG:

109334896

QSA:	O6P43_002730

PMUM:

MDM:

MSYL:

PCOX:

CSAV:

CSV:

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

RCU:

HBR:

POP:

PEU:

PALZ:

CILL:

TWL:

SLY:

SPEN:

SOT:

SSTN:

SDUL:

CANN:

NTA:	107775864 107777567 107791441

NSY:

104209956

NTO:

104090511

NAU:	109218481 109228501

INI:

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CQI:	110683044 110712930

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ATS:

TDC:	119301370 119309070

TAES:

123103569 123111793 123121357

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MUS:

ZOF:	122012437 122014720

DCT:

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ACAK:

NCOL:

ATR:

CJF:

MIS:	MICPUN_60648

MPP:	MICPUCDRAFT_16619

GSL:	Gasu_28320

DFA:	DFA_03613(thoc6)

ACAN:

ACA1_331480

PIF:	PITG_11476

PSOJ:

PHYSODRAFT_501592

GTT:	GUITHDRAFT_113726

» show all

Reference

PMID:15998806

Authors

Masuda S, Das R, Cheng H, Hurt E, Dorman N, Reed R

Title

Recruitment of the human TREX complex to mRNA during splicing.

Journal

Genes Dev 19:1512-7 (2005)
DOI:10.1101/gad.1302205

Sequence

[hsa:79228]

All links

Ontology (1)   
   TC (1)   
Gene (800)   
   MGENES (110)   
   RefGene (684)   
   OC (6)   
All databases (801)   

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