KEGG   ORTHOLOGY: K13310
Entry
K13310                      KO                                     

Name
desV, eryCI
Definition
dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase [EC:2.6.1.106]
Pathway
ko00523  Polyketide sugar unit biosynthesis
ko01100  Metabolic pathways
ko01110  Biosynthesis of secondary metabolites
Module
M00797  dTDP-D-desosamine biosynthesis
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00523 Polyketide sugar unit biosynthesis
    K13310  desV, eryCI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
Enzymes [BR:ko01000]
 2. Transferases
  2.6  Transferring nitrogenous groups
   2.6.1  Transaminases
    2.6.1.106  dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
     K13310  desV, eryCI; dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucose transaminase
Other DBs
RN: R06426
Genes
SRN: A4G23_00481(fdtB_1)
SPAV: Spa2297_32850
SALJ: SMD11_1659
SHAW: CEB94_04710
SEN: SACE_0734(eryCI)
ACTI: UA75_17820
ACAD: UA74_17285
AHG: AHOG_15460(fdtB2)
PLAB: C6361_24070
PLAT: C6W10_35925
AG: AAC68680(desV)
 » show all
Reference
  Authors
Burgie ES, Thoden JB, Holden HM
  Title
Molecular architecture of DesV from Streptomyces venezuelae: a PLP-dependent transaminase involved in the biosynthesis of the unusual sugar desosamine.
  Journal
Protein Sci 16:887-96 (2007)
DOI:10.1110/ps.062711007
Reference
  Authors
Szu PH, He X, Zhao L, Liu HW
  Title
Biosynthesis of TDP-D-desosamine: identification of a strategy for C4 deoxygenation.
  Journal
Angew Chem Int Ed Engl 44:6742-6 (2005)
DOI:10.1002/anie.200501998
Reference
PMID:9770448
  Authors
Xue Y, Zhao L, Liu HW, Sherman DH
  Title
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity.
  Journal
Proc Natl Acad Sci U S A 95:12111-6 (1998)
DOI:10.1073/pnas.95.21.12111
  Sequence

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