KEGG   ORTHOLOGY: K14326
Entry
K14326                      KO                                     

Name
UPF1, RENT1
Definition
regulator of nonsense transcripts 1 [EC:3.6.4.-]
Pathway
ko03013  RNA transport
ko03015  mRNA surveillance pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09120 Genetic Information Processing
  09122 Translation
   03013 RNA transport
    K14326  UPF1, RENT1; regulator of nonsense transcripts 1
   03015 mRNA surveillance pathway
    K14326  UPF1, RENT1; regulator of nonsense transcripts 1
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K14326  UPF1, RENT1; regulator of nonsense transcripts 1
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.4  Acting on acid anhydrides to facilitate cellular and subcellular movement
    3.6.4.-  
     K14326  UPF1, RENT1; regulator of nonsense transcripts 1
Messenger RNA biogenesis [BR:ko03019]
 Eukaryotic type
  mRNA surveillance and transport factors
   Surveillance factors
    Surveillance complex
     K14326  UPF1, RENT1; regulator of nonsense transcripts 1
   mRNA cycle factors
    Common to processing body (P body) and stress granule
     K14326  UPF1, RENT1; regulator of nonsense transcripts 1
Other DBs
COG: COG1112
Genes
HSA: 5976(UPF1)
PTR: 456373(UPF1)
GGO: 101152393(UPF1)
PON: 103893082(UPF1)
NLE: 100582659(UPF1)
MCC: 720288(UPF1)
MCF: 101866172(UPF1)
CSAB: 103234195(UPF1)
RRO: 104680634(UPF1)
CJC: 100388434(UPF1)
MMU: 19704(Upf1)
MCAL: 110299629(Upf1)
MPAH: 110336868(Upf1)
RNO: 684558(Upf1)
MUN: 110549166(Upf1)
CGE: 100765798(Upf1)
NGI: 103726857(Upf1)
HGL: 101704366(Upf1)
CCAN: 109684931(Upf1)
TUP: 106734733(UPF1)
CFA: 476664(UPF1)
VVP: 112913074(UPF1)
AML: 100480150(UPF1)
UMR: 103675150(UPF1)
UAH: 113256732(UPF1)
ORO: 101380112(UPF1)
ELK: 111143778
FCA: 101096043(UPF1)
PTG: 102972099(UPF1)
PPAD: 109247642(UPF1)
AJU: 106969136(UPF1)
BTA: 532933(UPF1)
BOM: 102270024(UPF1)
BIU: 109560814(UPF1)
BBUB: 102407534(UPF1)
CHX: 102189849(UPF1)
OAS: 101107598(UPF1)
SSC: 100738783(UPF1)
CFR: 102511479(UPF1)
CDK: 105101912(UPF1)
BACU: 103003571(UPF1)
LVE: 103082780(UPF1)
OOR: 101273793(UPF1)
DLE: 111166517(UPF1)
PCAD: 102975873(UPF1)
ECB: 100071059(UPF1)
EPZ: 103565075(UPF1)
EAI: 106846482(UPF1)
MYB: 102256312(UPF1)
MYD: 102760523(UPF1)
MNA: 107535340(UPF1)
HAI: 109382426(UPF1)
DRO: 112304965(UPF1)
PALE: 102884453(UPF1)
RAY: 107503721(UPF1)
MJV: 108406009(UPF1)
LAV: 100654230(UPF1)
TMU: 101361458
MDO: 100012828(UPF1)
SHR: 100929203(UPF1)
PCW: 110223386(UPF1)
OAA: 100078364(UPF1) 114808759
GGA: 420119(UPF1)
MGP: 100548164(UPF1)
CJO: 107325348(UPF1)
NMEL: 110388864(UPF1)
APLA: 101804967(UPF1)
ACYG: 106047929(UPF1)
TGU: 100223354(UPF1)
LSR: 110482937(UPF1)
SCAN: 103824543(UPF1)
GFR: 102035599(UPF1)
FAB: 101809945(UPF1)
PHI: 102107506(UPF1)
CCAE: 111940326(UPF1)
CCW: 104697422(UPF1)
ETL: 114071350(UPF1)
FPG: 101923816(UPF1)
FCH: 102058336(UPF1)
CLV: 102095827(UPF1)
EGZ: 104129801(UPF1)
NNI: 104013722(UPF1)
ACUN: 113489302(UPF1)
PADL: 103923284(UPF1)
AAM: 106496801(UPF1)
ASN: 102384608(UPF1)
AMJ: 102576388(UPF1)
PSS: 102450038(UPF1)
CMY: 102939480(UPF1)
CPIC: 101937566(UPF1)
PVT: 110072530(UPF1)
PBI: 103068004(UPF1)
PMUR: 107282856(UPF1)
TSR: 106543970(UPF1)
PMUA: 114588243(UPF1)
GJA: 107105636(UPF1)
XLA: 108712392 444289(upf1.S)
XTR: 100135270(upf1)
NPR: 108786383(UPF1)
DRE: 406783(upf1)
SGH: 107552677 107596255(upf1)
CCAR: 109090026(upf1)
IPU: 108280546(upf1)
PHYP: 113533264(upf1)
AMEX: 103031971(upf1)
EEE: 113585957(upf1)
NCC: 104944846(upf1) 104958147
ONL: 100693655 100695574(upf1)
OLA: 101168695(upf1)
XCO: 114146737 114150704(upf1)
PRET: 103463333(upf1) 103479258
CVG: 107088263(upf1)
NFU: 107392833(upf1)
KMR: 108234349(upf1)
ALIM: 106532231(upf1)
CSEM: 103394659(upf1) 103398864
LCF: 108883653 108902765(upf1)
HCQ: 109519015(upf1)
MALB: 109966845(upf1) 109969255
ELS: 105024419 105026208(upf1)
SFM: 108930585(upf1)
PKI: 111860382(upf1)
LCM: 102352262(UPF1)
CMK: 103182058(upf1)
RTP: 109920046(upf1)
CIN: 100181729
SPU: 581723
DME: Dmel_CG1559(Upf1)
DER: 6551354
DSI: Dsimw501_GD24645(Dsim_GD24645)
DSR: 110181835
DPE: 6598302
DWI: 6648598
DAZ: 108619155
DHE: 111605317
AAG: 5575411
AALB: 109405747
AME: 409839
BIM: 100746177
BTER: 100644215
CCAL: 108631268
OBB: 114879215
SOC: 105199267
MPHA: 105833387
AEC: 105154333
ACEP: 105618749
PBAR: 105427848
VEM: 105566938
HST: 105182511
DQU: 106751105
CFO: 105258992
LHU: 105674128
PGC: 109856725
OBO: 105283375
PCF: 106790902
NVI: 100120483
CSOL: 105359351
MDL: 103577127
TCA: 662109
DPA: 109539788
ATD: 109599631
NVL: 108562274
API: 100160197
BTAB: 109043732
CLEC: 106666507
ZNE: 110838082
CSCU: 111626836
PTEP: 107441024
CEL: CELE_C05C10.2(C05C10.2) CELE_C44H9.4(C44H9.4) CELE_Y48G8AL.6(smg-2)
BMY: Bm1_48950
SHX: MS3_04606
HMG: 100203524(upf1)
ATH: AT5G47010(LBA1)
ALY: 9301225
CRB: 17876346
BRP: 103853766
BOE: 106327103
CPAP: 110817491
CIT: 102615436
TCC: 18606113
EGR: 104443591
FVE: 101299192
RCN: 112175420
PPER: 18777232
PMUM: 103328883
PAVI: 110756272
CSV: 101214107
CMO: 103490818
MCHA: 111022653
RCU: 8263716
JCU: 105636460
MESC: 110604816
JRE: 109011455
VVI: 100264343
SIND: 105155974
OEU: 111389897
HAN: 110930521
CCAV: 112520815
BVG: 104892888
SOE: 110781662
OSA: 4343292
DOSA: Os07t0495900-01(Os07g0495900)
OBR: 102700817
BDI: 100838876
ATS: 109763115(LOC109763115)
SBI: 8077469
ZMA: 100383288(pco090939)
SITA: 101755895
PEQ: 110022886
ATR: 18448386
CRE: CHLREDRAFT_96867(UPF1)
OLU: OSTLU_443
SCE: YMR080C(NAM7)
KMX: KLMA_50219(NAM7)
NCS: NCAS_0A07730(NCAS0A07730)
NDI: NDAI_0H02120(NDAI0H02120)
TPF: TPHA_0C03950(TPHA0C03950)
TBL: TBLA_0B05540(TBLA0B05540)
TDL: TDEL_0A02660(TDEL0A02660)
KAF: KAFR_0A01950(KAFR0A01950)
CAL: CAALFM_C500500WA(NAM7)
NCR: NCU04242(prd-6)
BFU: BCIN_14g02530(Bcnam7)
MBE: MBM_04678
ANI: AN0646.2
ANG: ANI_1_848074(An08g06050)
ABE: ARB_06689
TVE: TRV_04033
PTE: PTT_08860
SPO: SPAC16C9.06c(upf1)
CNE: CNC02960
CNB: CNBC4250
MGL: MGL_2074
DDI: DDB_G0288923(upf1)
EHI: EHI_035550(17.t00041)
TCR: 511317.30
 » show all
Reference
  Authors
Kashima I, Yamashita A, Izumi N, Kataoka N, Morishita R, Hoshino S, Ohno M, Dreyfuss G, Ohno S
  Title
Binding of a novel SMG-1-Upf1-eRF1-eRF3 complex (SURF) to the exon junction complex triggers Upf1 phosphorylation and nonsense-mediated mRNA decay.
  Journal
Genes Dev 20:355-67 (2006)
DOI:10.1101/gad.1389006
  Sequence
[hsa:5976]
Reference
  Authors
Chamieh H, Ballut L, Bonneau F, Le Hir H
  Title
NMD factors UPF2 and UPF3 bridge UPF1 to the exon junction complex and stimulate its RNA helicase activity.
  Journal
Nat Struct Mol Biol 15:85-93 (2008)
DOI:10.1038/nsmb1330
  Sequence
[hsa:5976]
Reference
  Authors
Jeong HJ, Kim YJ, Kim SH, Kim YH, Lee IJ, Kim YK, Shin JS
  Title
Nonsense-mediated mRNA decay factors, UPF1 and UPF3, contribute to plant defense.
  Journal
Plant Cell Physiol 52:2147-56 (2011)
DOI:10.1093/pcp/pcr144
  Sequence
[ath:AT5G47010]

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