KEGG   ORTHOLOGY: K15093
Entry
K15093            Tight     KO                                     
Symbol
E1.14.14.143
Name
(+)-menthofuran synthase [EC:1.14.14.143]
Pathway
map00902  Monoterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R08923  (+)-pulegone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (9-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00902 Monoterpenoid biosynthesis
    K15093  E1.14.14.143; (+)-menthofuran synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.143  (+)-menthofuran synthase
     K15093  E1.14.14.143; (+)-menthofuran synthase
Other DBs
GO: 0052582
Genes
AG: AAL06397
Reference
  Authors
Bertea CM, Schalk M, Karp F, Maffei M, Croteau R
  Title
Demonstration that menthofuran synthase of mint (Mentha) is a cytochrome P450 monooxygenase: cloning, functional expression, and characterization of the responsible gene.
  Journal
Arch Biochem Biophys 390:279-86 (2001)
DOI:10.1006/abbi.2001.2378
  Sequence
Reference
  Authors
Mahmoud SS, Croteau RB
  Title
Menthofuran regulates essential oil biosynthesis in peppermint by controlling a downstream monoterpene reductase.
  Journal
Proc Natl Acad Sci U S A 100:14481-6 (2003)
DOI:10.1073/pnas.2436325100
  Sequence

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