KEGG ORTHOLOGY: K22210

ORTHOLOGY: K22210

Entry

K22210                      KO

Symbol

DGLUCY

Name

D-glutamate cyclase [EC:4.2.1.48]

Pathway

map00470

D-Amino acid metabolism

map01100

Metabolic pathways

Reaction

R01583

D-glutamate hydro-lyase (cyclizing; 5-oxo-D-proline-forming)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K22210  DGLUCY; D-glutamate cyclase
Enzymes [BR:ko01000]
4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.48  D-glutamate cyclase
     K22210  DGLUCY; D-glutamate cyclase

Other DBs

GO:

0047820

Genes

HSA:	80017(DGLUCY)

PTR:	453104(DGLUCY)

PPS:	100971567(DGLUCY)

GGO:	101153207(DGLUCY)

PON:	100172319(DGLUCY)

PPYG:

129012156(DGLUCY)

NLE:	100586901(DGLUCY)

HMH:	116456096(DGLUCY)

SSYN:

129487535(DGLUCY)

MCC:	700168(DGLUCY)

MCF:	102135732(DGLUCY)

MTHB:

126959650

MNI:	105467555(DGLUCY)

CSAB:

103229551(C24H14orf159)

CATY:

105596569

PANU:

101012503(DGLUCY)

TGE:	112628451(DGLUCY)

MLEU:

105548007

RRO:	104656701(DGLUCY)

RBB:	108523309(CUNH14orf159)

TFN:	117071547(DGLUCY)

PTEH:

111538216(DGLUCY)

CANG:

105517296

CJC:	100412631(DGLUCY)

SBQ:

101047007

CIMI:

108316818(DGLUCY)

ANAN:

105717760(DGLUCY)

CSYR:

103275586(CUNH14orf159)

MMUR:

105876286(C3H14orf159)

PCOQ:

105822929

OGA:	100949551(DGLUCY)

MMU:	217830(Dglucy)

MCAL:

110306840(Dglucy)

MPAH:

110324645(C7H14orf159)

RNO:	362769(Dglucy)

MCOC:

116080006(Dglucy)

ANU:	117696943(Dglucy)

ASYL:

127687030(Dglucy)

MUN:	110558364(Dglucy)

CGE:	100753550(Dglucy)

MAUA:

101828173(Dglucy)

PROB:

127231067(Dglucy)

PLEU:

114705025(Dglucy)

MORG:

121434364(Dglucy)

MFOT:

126507214

AAMP:

119818709(Dglucy)

NGI:	103724611(CUNH14orf159)

HGL:

101711224

CPOC:

100735106(Dglucy)

CCAN:

109699498(CUNH14orf159)

NCAR:

124976082

MMMA:

107144620(Dglucy)

ITI:	101967644(Dglucy)

TUP:

102469364

GVR:

103603089

CFA:	100688910(DGLUCY)

VVP:	112907347(DGLUCY)

VLG:	121492493(DGLUCY)

NPO:	129496335(DGLUCY)

AML:	100482436(DGLUCY)

UMR:	103670181(DGLUCY)

UAH:	113267360(DGLUCY)

UAR:	123798891(DGLUCY)

ELK:

111148542

LLV:

125104759

MPUF:

101689641

MNP:	132000092(DGLUCY)

MLK:	131836763(DGLUCY)

NVS:	122893791(DGLUCY)

ORO:

101371157

EJU:	114204443(DGLUCY)

ZCA:	113909354(DGLUCY)

MLX:	118002490(DGLUCY)

NSU:	110571747(DGLUCY)

LWW:	102744332(DGLUCY)

FCA:	101085897(DGLUCY)

PYU:	121032192(DGLUCY)

PCOO:

112855858(DGLUCY)

PBG:	122468118(DGLUCY)

PVIV:

125168765(DGLUCY)

LRUF:

124512240

LGF:	123583749(DGLUCY)

AJU:	106987920(DGLUCY)

PTG:

102949759

PPAD:

109274456(CUNH14orf159)

PUC:

125909251

PLEZ:

122223055(DGLUCY)

HHV:	120232099(DGLUCY)

BBIS:

104985863

CSUM:

138095018(DGLUCY)

MREE:

136146986(DGLUCY)

MBEZ:

129550093(DGLUCY)

SSC:	100626547(C7H14orf159)

CFR:	102521322(DGLUCY)

CBAI:

105079860

CDK:	105095965(DGLUCY)

VPC:	102529318(DGLUCY)

BACU:

102999377

BMUS:

118889531(DGLUCY)

LVE:

103084864

OOR:	101287758(DGLUCY)

LALB:

132527226(DGLUCY)

GMF:	115867105(DGLUCY)

DDP:	132417584(DGLUCY)

DLE:	111175940(DGLUCY)

PSIU:

116746127(DGLUCY)

PPHC:

136118332(DGLUCY)

NASI:

112393856(DGLUCY)

ECB:	100063012(DGLUCY)

EPZ:	103558013(DGLUCY)

EAI:	106825335(DGLUCY)

MYB:

102252495

MYD:

102753826

MMYO:

118659289(DGLUCY)

MLF:	102432492(DGLUCY)

MDT:	132230517(DGLUCY)

MYUM:

139009520 139010418

PKL:	118712976(DGLUCY)

EFUS:

103292237(DGLUCY)

MNA:

107531588

DRO:	112311934(DGLUCY)

SHON:

118976806(DGLUCY)

AJM:	119037910(DGLUCY)

PDIC:

114492950(DGLUCY)

PHAS:

123808597(DGLUCY)

MMF:	118636098(DGLUCY)

PPAM:

129065828(DGLUCY)

HAI:	109382680(CUNH14orf159)

RFQ:	117023309(DGLUCY)

PALE:

102898067(DGLUCY)

PGIG:

120619609(DGLUCY)

PVP:	105300806(DGLUCY)

RAY:	107515436(DGLUCY)

MJV:	108399442(DGLUCY)

TOD:	119239281(DGLUCY)

SARA:

101546022

SFUM:

130041375(DGLUCY)

SETR:

126003636(DGLUCY)

LAV:	100659904(DGLUCY)

ETF:	101646009(DGLUCY)

DNM:	101419340(DGLUCY)

MDO:	100017774(C1H14orf159)

GAS:	123234039(DGLUCY)

SHR:	100931620(DGLUCY)

AFZ:

127549411

PCW:	110217799(CUNH14orf159)

TVP:	118829960(DGLUCY)

MLAO:

141522241(DGLUCY)

OAA:	100083826(DGLUCY)

TACU:

119931952(DGLUCY)

GGA:	423409(C5H14orf159)

PCOC:

116228912(DGLUCY)

MGP:	100539918(DGLUCY)

CJO:	107315200(DGLUCY)

TPAI:

128085985(DGLUCY)

LMUT:

125695522(DGLUCY)

NMEL:

110402184(C6H14orf159)

APLA:

101791243(DGLUCY)

ACYG:

106036649(DGLUCY)

CATA:

118244812(DGLUCY)

AFUL:

116489751(DGLUCY)

TGU:	100229540(DGLUCY)

LSR:	110471379(DGLUCY)

SCAN:

103826477(DGLUCY)

PMOA:

120503771(DGLUCY)

OTC:	121332518(DGLUCY)

PRUF:

121355992(DGLUCY)

ATRC:

139589836(DGLUCY)

GFR:

102037421

FAB:	101806679(C5H14orf159)

OMA:	130254191(DGLUCY)

PHI:

102108442

PMAJ:

107205561(DGLUCY)

CCAE:

111929884(DGLUCY)

CCW:	104685987(DGLUCY)

CBRC:

103612114(CUNH14orf159)

ACOE:

138111768(DGLUCY)

ETL:	114058212(DGLUCY)

ZAB:	102073109(DGLUCY)

ZLE:	135448097(DGLUCY)

ACHL:

103800958

SVG:

106849333

MMEA:

130576164(DGLUCY)

HRT:	120754034(DGLUCY)

SATI:

136362937(DGLUCY)

CCIC:

134044954(DGLUCY)

FPG:

101913280

FCH:	102058374(DGLUCY)

CCRI:

104161490

NNT:

104402204

SHAB:

115606770(DGLUCY)

ACUN:

113480812(DGLUCY)

TALA:

104364674(DGLUCY)

ACHC:

115333825(DGLUCY)

HALD:

104323816

HLE:

104841859

AGEN:

126050526

HHAR:

128140186(DGLUCY)

GCL:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

135179619(DGLUCY)

AVIT:

104266984

EGZ:	104135348(DGLUCY)

NNI:

PCRI:

PCAO:

PADL:

AFOR:

103900294(CUNH14orf159)

FGA:

104078679

GSTE:

104263081

CBOY:

140653269(DGLUCY)

CLV:	102096431(CUNH14orf159)

CNIC:

135989457(DGLUCY)

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

104059622(DGLUCY)

TEO:

104372077

BREG:

104639823

OHA:

104331484

ACAR:

104526349(DGLUCY)

CPEA:

104394155

CVF:

104286944

RTD:	128908986(DGLUCY)

CRID:

134515417(DGLUCY)

AAM:

106482923

AROW:

112972654(DGLUCY)

NPD:	112953467(DGLUCY)

TGT:

104568817

DNE:	112990234(DGLUCY)

SCAM:

104153782

ASN:	102380281(DGLUCY)

AMJ:	102576478(CUNH14orf159)

CPOO:

109321685(CUNH14orf159)

GGN:	109298523(CUNH14orf159)

PSS:	102453950(DGLUCY)

CMY:	102931212(DGLUCY)

CCAY:

125637746(DGLUCY)

DCC:	119857607(DGLUCY)

CPIC:

101937326(DGLUCY)

TST:	117876192(DGLUCY)

CABI:

116816894(DGLUCY)

MRV:	120403369(DGLUCY)

ACS:	100562196(c1h14orf159)

ASAO:

132763314(DGLUCY)

PVT:	110086580(CUNH14orf159)

SUND:

121914907(DGLUCY)

PBI:	103063698(DGLUCY)

PMUR:

107297288(DGLUCY)

CTIG:

120309571(DGLUCY)

TSR:

106546543

PGUT:

117665912(DGLUCY)

PCAE:

139308075(DGLUCY)

APRI:

131187848(DGLUCY)

PTEX:

113444344(DGLUCY)

NSS:	113419664(DGLUCY)

VKO:	123026939(DGLUCY)

PMUA:

114591021(DGLUCY)

PRAF:

128407957(DGLUCY)

ZVI:	118078179(DGLUCY)

HCG:	128334222(DGLUCY)

GJA:

107113340

STOW:

125426641(DGLUCY)

EMC:	129324474(DGLUCY)

XLA:	108698713(dglucy.L)

XTR:	549215(dglucy)

NPR:	108788696(CUNH14orf159)

RTEM:

120921213(DGLUCY)

ACAT:

141117249(DGLUCY)

BBUF:

120982146(DGLUCY)

BGAR:

122922084(DGLUCY)

DTC:	141092179(DGLUCY)

PWL:	138260057(DGLUCY)

MUO:	115477382(DGLUCY)

GSH:	117363399(DGLUCY)

DRE:	560387(dglucy)

SRX:

107730207

SANH:

107679776

SGH:

107582942

CCAR:

109107902(dglucy)

CAUA:

113117328(dglucy)

CGIB:

127976240

PTET:

122361840 122361911

LROH:

127180093(dglucy)

GRF:	141295216(dglucy)

OMC:	131523004(dglucy)

PPRM:

120476230(dglucy)

RKG:	130080235(dglucy)

MAMB:

125269384(dglucy)

CIDE:

127498091

CERY:

137006344(dglucy)

MASI:

127455145

TROS:

130560724(dglucy)

TDW:	130436517(dglucy)

MANU:

129417005 141362603

PDAB:

135778115(dglucy)

AMEX:

103041880(dglucy)

CMAO:

118823329(dglucy)

EEE:	113574126(dglucy)

CHAR:

105892847(dglucy)

SPIL:

134068117(dglucy)

TRU:	101064729(dglucy)

TFS:	130540108(dglucy)

PLEP:

121953640(dglucy)

SLUC:

116065766(dglucy)

ECRA:

117935476(dglucy)

ESP:	116669961(dglucy)

PFLV:

114546972(dglucy)

GAT:	120833002(dglucy)

PPUG:

119227288(dglucy)

AFB:	129103340(dglucy)

CLUM:

117751300(dglucy)

PSWI:

130201227(dglucy)

CANA:

137803305(dglucy)

CVE:	137877698(dglucy)

MSAM:

119910853(dglucy)

CUD:	121526235 121526683

SPUL:

138591051 138591328

LMIX:

132993072(dglucy)

ALAT:

119019729(dglucy)

ASTR:

137610775 137611078 137611174(dglucy)

MZE:	101472904(dglucy)

ONL:	100699337(dglucy)

OAU:	116327984(dglucy)

OLA:	101156702(dglucy)

OML:	112145000(dglucy)

CSAI:

133462528(dglucy)

XMA:	102226444(dglucy)

XCO:	114134371(dglucy)

XHE:	116709043(dglucy)

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122845725(dglucy)

PPRL:

129374892(dglucy)

CVG:

107101552

CTUL:

119785374(dglucy)

GMU:	124855425(dglucy)

NFU:	107391670(csgr16h14orf159)

KMR:	108247027(dglucy)

ALIM:

106521235

NWH:	119427802(dglucy)

AOCE:

111576395(dglucy)

MCEP:

125023124(dglucy)

CSEM:

103383443 103383463

POV:	109628237(cunh14orf159)

SSEN:

122782986(dglucy)

SSOE:

131444673(dglucy)

HHIP:

117756188(dglucy)

HSP:	118116005(dglucy)

PPLT:

128451405(dglucy)

SMAU:

118285923(dglucy)

LCF:	108886860 108896079 108897871

XGL:	120795425(dglucy)

HCQ:	109519777 109519787

SBIA:

133512835(dglucy)

PEE:	133412837(dglucy)

PTAO:

133487503(dglucy)

BPEC:

110163870 110166339(cunh14orf159)

ENY:	140370885(dglucy) 140370887

MALB:

109965009(cunh14orf159)

BSPL:

114848488(dglucy)

SJO:	128375284(dglucy)

SSCO:

134000761(dglucy)

GMH:	115544179(dglucy)

SASA:

106611165(cssa09h14orf159)

STRU:

115162142(dglucy)

OTW:	112256792(dglucy)

OMY:	110505723(dglucy)

OGO:	124046597(dglucy)

ONE:	115138649(dglucy)

OKI:	109904195(dglucy)

OKE:	118368150(dglucy)

OMM:	135525708(dglucy)

OCLA:

139383287

SALP:

111963420(dglucy)

SNH:	120023204(dglucy)

CCLU:

121544321(dglucy)

ELS:	105015466(dglucy)

OEP:	134026721(dglucy)

SFM:	108933257(dglucy)

PKI:	111852007(dglucy)

AANG:

118225631(dglucy)

AROT:

135253235(dglucy)

CCOG:

133128035(dglucy)

LOC:	102682775(clg7h14orf159) 102692206

PSPA:

121323817 121329475(dglucy)

ARUT:

117402760 117424686 117974027

PSEX:

120518516 120518648(dglucy)

LCM:

102346195

CMK:	103189663(dglucy)

RTP:	109913902(dglucy)

CPLA:

122553350(dglucy)

HOC:	132818004(dglucy)

LERI:

129700050(dglucy)

HAKA:

140724790(dglucy)

PMRN:

116948420(DGLUCY)

LRJ:	133352751(DGLUCY)

BFO:	118417907 118420680 118421745

BBEL:

109473801 109482494

CIN:	100180171 100182513

SCLV:

120326613

SPU:

577417

LPIC:

129264336

AJJ:	139961487 139970617 139979093

APLC:

110976733 110976775

ARUN:

117290761 117299680

AAMU:

139942182 139943313

AFIL:

140151959 140152984 140153652

AJC:

117111427

SKO:

100368287

PFLL:

139149981 139149983 139149985

NVE:	5517941 5520806

EPA:	110237437 110242750

ATEN:

116306890 116306892

ADF:

107345094

AMIL:

114950348 114963825

MCAZ:

138025969 138033625 138047290

MFOO:

137968974 137979731 138003157 138004071 138004082

PDAM:

113669485 113670518 113670519 113671845 113671883

SPIS:

111323950 111333603 111339366

DGT:

XEN:

HMG:

HSY:

RES:	135685622 135685664

AQU:

100637788

SRE:	PTSG_03849

FCY:	FRACYDRAFT_234119

TVA:	5468340(TVAGG3_0267260)

GTT:	GUITHDRAFT_115230

PCAF:

DSC91_003834 DSC91_007304

PACS:

FAZ98_16120 FAZ98_16130 FAZ98_30245

PAND:

DRB87_00220 DRB87_00230

BBH:	BN112_2783

BBM:	BN115_0626

BBX:	BBS798_0630

PIG:	EGT29_25985

DIH:	G7047_04775

SIMP:

C6571_14745 C6571_14755

MESO:

BSQ44_13830

SMQ:	SinmeB_6592

SMI:	BN406_06782

SMER:

DU99_19640

SFH:	SFHH103_04191 SFHH103_04193

SAME:

SAMCFNEI73_pC1585

SINO:

SS05631_a42580 SS05631_a42600

ESJ:	SJ05684_a37780

BOF:	FQV39_07995

CID:

PABY:

SAGU:

RSU:

RHM:	B5V46_17770

PAED:

G5B38_21360

KNA:	B0W47_14230

HADH:

FRZ61_46790

DMS:	E8L03_06740

GMR:	GmarT_08600

GIM:	F1728_09980

GPN:	Pan110_09310

MRI:	Mal4_49100

SDYN:

Mal52_21760

PLON:

Pla110_04020

GOG:	C1280_24635

TIM:	GMBLW1_22520

LRS:	PX52LOC_06605

FTJ:

FTUN_6987

TSPH:

KIH39_25660

FWA:	DCMF_00955

LPIL:

LIP_2227

BLB:	BBMN68_890

BLZ:	BLGT_03245

BLA:

BLA_0133

BLC:	Balac_0142

BLT:	Balat_0142

BBB:

BIF_01419

BBC:

BLC1_0133

BNM:	BALAC2494_00981

BLV:

BLW:

BLS:

BANI:

BANL:

BANM:

BDE:

BDN:

BTP:

RIV:	Riv7116_1919

FIS:	FIS3754_24270

FFO:	FFONT_0039

CSU:	CSUB_C1123

BARC:

AOA65_1114

» show all

Reference

PMID:28266638

Authors

Ariyoshi M, Katane M, Hamase K, Miyoshi Y, Nakane M, Hoshino A, Okawa Y, Mita Y, Kaimoto S, Uchihashi M, Fukai K, Ono K, Tateishi S, Hato D, Yamanaka R, Honda S, Fushimura Y, Iwai-Kanai E, Ishihara N, Mita M, Homma H, Matoba S

Title

D-Glutamate is metabolized in the heart mitochondria.

Journal

Sci Rep 7:43911 (2017)
DOI:10.1038/srep43911

Sequence

[mmu:217830]

All links

Ontology (1)   
   GO (1)   
Gene (913)   
   MGENES (393)   
   RefGene (514)   
   OC (6)   
All databases (914)   

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