KEGG   Histoplasma mississippiense: HCAG_04357
Entry
HCAG_04357        CDS       T02229                                 
Name
(RefSeq) formate--tetrahydrofolate ligase
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
aje  Histoplasma mississippiense
Pathway
aje00670  One carbon pool by folate
aje01100  Metabolic pathways
aje01240  Biosynthesis of cofactors
Module
aje_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:aje00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    HCAG_04357
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:aje04147]
    HCAG_04357
Enzymes [BR:aje01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     HCAG_04357
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     HCAG_04357
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     HCAG_04357
Exosome [BR:aje04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   HCAG_04357
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH AdoHcyase_NAD
Other DBs
NCBI-GeneID: 5447081
NCBI-ProteinID: XP_001540517
AA seq 889 aa
MAAVKIDGTTIAKNIRERLNVEIQKSQETNPRFKPCLVIFQIGDRSDSSTYVRMKLKAAK
EANIHCKLNKFAEDISEPELLQEISLANNDPSVHGIIVQLPLPSHLSEHSITSAVAAEKD
VDGFGAVNIGELAKRGGKPLFVPCTPQGVMELLRTTGVELAGKNAVVLGRSDVVGSPVSY
LLKSADATVTVCHSKTKNLEAIVKDADILVAAIGKPEFVKGSWLRPGVVVIDVGTNYIPD
ATKKSGQRHITPLPIKLQSPVPSDIAISRAQRPKPITQIAAEVGIEPHELEPYGHTKAKV
SLDLLDRLSHRRNGRYILVSGITPTPLGEGKSTTTMGLTQALGAHLNRVVFANVRQPSQG
PTFGIKGGAAGGGYSQVIPMDEFNLHLTGDIHAITAANNLLAAAIETRMFHESTQSDAAL
YKRLVPVKKGKREFQSIFFRRLKKLGITKTDPNDLTPEEINRFARLDIDPETITWRRVLD
VNDRHLRTITVGQAATEKGHTRQTGFDISVASECMAILALSNDLGDMRERLGRMVVATSK
NGDPVTCDDIGCGGALAALMRDAIKPNLMQSLEGTPVFVHAGPFANISIGANSVVADKLA
LKLAGTEPDEDHEAKTGFVVTEAGFDFTMGGERFFNIKCRSSGLVPDTVVIVATVRAIKA
HGGGPPIAPGAPLAAEYTTENVELLRNGCVNLKKQIENAKRYGIPVVVAINKFETDTDAE
VAVIREEAIAAGAEDAIPANHWAEGGAGAVDLAKGVIIASSKPKDFKLLYDLEGTVQERI
ERIGKEMYGAAKVEFSELAQKKVDSYTKQGFGNLPICIAKTQYSLSHDPNLKGAPTGFTV
PIRDVRLAVGAGYLYALAADIQTIPGLPTAPGYLNVDVDAETGEIDGLF
NT seq 2670 nt   +upstreamnt  +downstreamnt
atggcggctgtcaagattgatggcactacaattgccaaaaacatcagggagcgcctgaat
gtcgagattcagaagtcacaggaaaccaatcctaggttcaagccttgcttggtcattttc
caaattggcgacagatcagattccagcacttatgtgcgcatgaagctgaaggctgctaag
gaggcaaatatacactgcaaacttaacaaattcgctgaagatatcagcgaacccgaactg
cttcaagaaatctcactcgcaaacaacgacccgagcgtgcatggcattatcgtccaatta
cctctcccaagccacctttccgaacattctattacatctgctgtcgctgcggagaaagat
gttgacggctttggagctgtcaatattggagagctggccaagcgaggaggcaagcctctg
tttgttccatgcaccccccagggagtaatggaactccttcgtaccactggagttgagctg
gccggcaaaaatgccgtggttttgggcagaagtgacgttgttggaagccctgtcagctac
ttgttgaagagtgcggatgccactgtcactgtctgccactcgaaaaccaaaaacttggaa
gccattgtcaaggatgcagatatcttggttgctgccattgggaaacccgagtttgtcaag
ggttcgtggcttcgaccgggcgtggtggtcatcgatgttggcaccaactacattcctgac
gcaacgaagaaatcaggccaacggcacatcacacctctacctatcaagcttcaaagccca
gtcccctcagacatcgccatctctcgagcccagcggcccaagcctattacccagattgcc
gcagaggtcggcattgaaccgcacgagttagagccatacggacataccaaggccaaggtt
agccttgaccttttagatcgtctatctcaccgccgtaacggacgctatattttggtatcc
ggaatcaccccaacccctctaggggaaggcaaatcgaccacgactatgggtctcacacag
gctcttggcgcccatctcaacagggtagtcttcgccaacgtccgacagcccagtcaaggc
cctaccttcggaatcaagggcggtgcagctggaggaggatacagccaggtcatccctatg
gacgaattcaaccttcacttgaccggtgacattcatgctattacggctgcaaacaacttg
ctagcagctgctatcgaaacgagaatgttccacgaatccacgcaaagcgacgctgcgcta
tataaacggctagtgccagtcaagaaggggaaacgcgaattccaaagcatcttcttccga
cgattgaagaaattagggattacaaaaacggacccaaacgacctaacaccagaggaaatc
aaccgcttcgcaagattggatattgacccggagaccattacctggcggagagtcctggac
gtgaacgacaggcacctgcgtaccataacggttggccaggctgcaaccgagaaaggccac
actagacagaccggctttgatatctccgttgcaagcgagtgtatggccatcctcgccctt
agcaatgaccttggcgacatgcgagaacgccttggtagaatggtggttgcaacgtctaag
aacggcgatcccgtcacttgcgacgacattggctgcgggggcgccctcgctgcgctgatg
agggatgcaattaaaccaaatctcatgcaaagtctcgagggaacgccagtgtttgtccac
gctgggcccttcgccaacatcagcattggcgccaattccgtcgtggcggataaactcgcc
ctgaaactggcaggcacagagccagacgaggaccatgaagcaaagaccgggttcgtcgtc
accgaagccggcttcgatttcaccatgggcggcgagcggttcttcaacatcaagtgccgc
tcgtcaggcctcgttccggacacggtggtcatcgtcgccaccgtccgagccatcaaggct
cacggaggcgggccccctatcgcccccggcgccccgctggctgcagaatacacgaccgaa
aacgtagaactgttacgaaacggctgcgtcaatctgaagaaacagatcgaaaacgcaaag
cgctacggcatccccgtcgtggtcgccatcaacaaattcgaaaccgacacggacgccgag
gtcgcggtgattcgcgaagaggcaatcgccgcaggcgcggaggatgctattcccgccaac
cactgggcggagggtggtgccggagccgtcgacctagccaagggcgtcatcatcgccagc
tcgaagcccaaggatttcaagctgctgtatgatctcgagggcacggtacaggagcgcatc
gagcgcatcgggaaggagatgtacggcgccgcgaaggtggagttcagtgagcttgcgcag
aagaaggtcgactcgtataccaagcagggctttggaaacctcccgatctgcattgcgaag
acgcagtattcgctcagtcacgatccgaacctcaagggtgcgccgaccggcttcaccgtt
ccaatcagggatgtcaggcttgccgttggtgcgggatatttgtacgcactcgccgctgat
atccaaaccatccccggcctccccactgcacccggatatctcaatgtcgatgttgatgcc
gagactggcgaaattgatggtcttttctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (17)   
   KEGG ORTHOLOGY (1)   
   RefGene (13)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (4)   
   Pfam (4)   
All databases (49)   

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