KEGG   Ailuropoda melanoleuca (giant panda): 100469453
Entry
100469453         CDS       T01329                                 
Symbol
DDX58
Name
(RefSeq) antiviral innate immune response receptor RIG-I
  KO
K12646  ATP-dependent RNA helicase DDX58 [EC:5.6.2.6]
Organism
aml  Ailuropoda melanoleuca (giant panda)
Pathway
aml04064  NF-kappa B signaling pathway
aml04622  RIG-I-like receptor signaling pathway
aml04623  Cytosolic DNA-sensing pathway
aml05160  Hepatitis C
aml05161  Hepatitis B
aml05162  Measles
aml05164  Influenza A
aml05168  Herpes simplex virus 1 infection
aml05169  Epstein-Barr virus infection
aml05171  Coronavirus disease - COVID-19
Brite
KEGG Orthology (KO) [BR:aml00001]
 09130 Environmental Information Processing
  09132 Signal transduction
   04064 NF-kappa B signaling pathway
    100469453 (DDX58)
 09150 Organismal Systems
  09151 Immune system
   04622 RIG-I-like receptor signaling pathway
    100469453 (DDX58)
   04623 Cytosolic DNA-sensing pathway
    100469453 (DDX58)
 09160 Human Diseases
  09172 Infectious disease: viral
   05161 Hepatitis B
    100469453 (DDX58)
   05160 Hepatitis C
    100469453 (DDX58)
   05171 Coronavirus disease - COVID-19
    100469453 (DDX58)
   05164 Influenza A
    100469453 (DDX58)
   05162 Measles
    100469453 (DDX58)
   05168 Herpes simplex virus 1 infection
    100469453 (DDX58)
   05169 Epstein-Barr virus infection
    100469453 (DDX58)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04054 Pattern recognition receptors [BR:aml04054]
    100469453 (DDX58)
Enzymes [BR:aml01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     100469453 (DDX58)
Pattern recognition receptors [BR:aml04054]
 Cytoplasmic pattern recognition receptors
  RIG-I-like receptors
   100469453 (DDX58)
SSDB
Motif
Pfam: CARD_2 RIG-I_C RIG-I_C-RD DEAD ResIII Helicase_C AAA_22 PTS_IIB AAA_25 CorA
Other DBs
NCBI-GeneID: 100469453
NCBI-ProteinID: XP_002928312
Ensembl: ENSAMEG00000003766
UniProt: D2HZI2
Position
7:complement(23000415..23037244)
AA seq 928 aa
MSAEDRQNLHAFRDYVVKTLDPTYILSYMAPWFKDDKVQHIQAEKNNKGTTEAASLFLKF
LLELQEEGWFRGFLDALGHAGYSGLYEAIETWDFRKIESLEEYRLLLKRLQPEFKTTVNP
KDILPEISGCLISQECEEIIQVCSNKGLMAGAEKMAECLLRSDKENWPKTLKLALEIEES
QFSQLWIMDKDAKNVEPKVLEDDEIETSDIQIFYKEEPECQNLSQNPSPPSASPTFTQLK
PRNYQLELALPAKEGKNTIICAPTGCGKTFVSLLICEHHLKKFPQGQKGKVVFFAIQLPV
YEQQKSVFSKYFEKLGYKVAGVSGATSEIVSVEEIVENYDIIILTPQILVNSLRKGTVPS
LSVFTLMIFDECHNTGKHHPYNMIMFNYLDQKLGGSSDPLPQVIGLTASVGTGDAKNTTE
AMEYICKLCASLDTSVIATVKDNLEELEEIVYKPQKFFRKVKLRTTDRFKCIISQLMRET
ESLAKKIFDELSTVTLENVFQIQNRNFGTQKYEQWILSVQKTCILFQLPDKEEESRICKA
LYLYTSHLRKYNDALIINEHARMKDALDYLKDFFANVRAAGFDEIEQHLTWRFEEKLREL
ESVSMDPGNENPKLQDLSFILQEEYHLNPESRTILFVKTRALVDALKKWIEENSELSFLK
PGILTGRGKTNQNTGMTLPAQKCALDAFRTDGDKKILIATSVADEGIDIAQCNLVILYEY
VGNVIRMIQTRGRGRARGSKCFLLTSNADVIEKEKINIHKEKMMNDSILRLQTWNEAVFK
EKVLQIQIQEKLIRDSQGKVERVPDKENKKLLCRKCKGFACYTADIRVVEDCHYTVVGDD
FRKCYVSKLHPKPKSFGYFEKTAKIFCSREDCSHDWGIHVKYKTFEIPVIKIESFVVEDI
ATGAQKLYAKWRDFPLQKIPFDAAEMSK
NT seq 2787 nt   +upstreamnt  +downstreamnt
atgtcggctgaggatcggcagaatctgcacgccttccgggactatgtcgtgaagactctg
gaccctacgtacatcctgagctacatggccccctggtttaaggacgacaaggtgcagcat
atccaggctgagaaaaacaataagggcacgacagaggccgcctcactttttcttaagttc
ctattggagctccaggaagaaggctggttccgtggctttttggatgcccttggtcatgca
ggttattctggactttatgaagccattgaaacttgggatttccgaaaaattgaaagtcta
gaggagtacagattgcttttaaagcgtttacagccagaatttaaaaccacagttaatcca
aaagatatccttcctgaaatatctggatgtttaattagtcaggaatgtgaagaaatcata
caggtttgttccaacaaggggctgatggcaggtgctgagaaaatggccgaatgccttctc
agatcagacaaggaaaactggcccaaaactttgaaacttgctttggagatagaagagagc
cagttcagtcaactgtggattatggacaaagatgcaaaaaatgttgaaccgaaagtcctt
gaggatgatgaaatagaaacttctgacatacagattttctataaggaagaaccagaatgc
cagaatcttagtcagaacccatctccgccttcagcctctcctactttcacccaactgaag
ccaagaaattaccaacttgagctcgcgttgcctgctaaggaaggaaaaaacacaataata
tgtgctcctactggttgtggaaaaacctttgtttcccttcttatatgtgaacatcatctt
aaaaaatttccacaaggacaaaaagggaaggttgttttttttgctattcagctccccgtg
tatgaacagcagaaatccgtgttctccaaatattttgaaaaacttgggtacaaagttgca
ggtgtttctggagcaacatctgagattgtctcagtggaagagattgttgagaactatgac
atcatcattttaactccacagattcttgtgaatagtcttagaaaagggactgttccatca
ctctctgtctttactttgatgatatttgatgaatgtcacaacaccggtaaacaccatcct
tacaatatgatcatgtttaattatctggatcagaaacttggaggatcttcagacccactg
cctcaggtcattgggctgactgcctcggttggcactggggatgccaaaaacacaacagaa
gccatggaatatatctgcaaactgtgtgcttctcttgacacatcagtgatagcaacagtc
aaagacaacttggaagaattggaagaaattgtttataagccccagaagtttttcaggaaa
gtgaaattacggactactgacagatttaaatgcatcatatctcagctgatgagggaaaca
gagagtctggcaaagaagatctttgacgagctcagtaccgtaactctcgaaaatgtattt
caaattcaaaataggaattttggaacacagaaatacgaacaatggatcctttctgttcag
aaaacatgcattttgtttcagttgcccgacaaagaagaggagagcaggatttgtaaagcc
ctgtatttgtacacttcccacttgcggaaatataatgatgccctcattatcaatgagcat
gcccggatgaaagatgctctggattacttgaaagacttcttcgctaatgtccgagcagca
ggatttgatgagattgagcagcatctcacctggagatttgaagaaaaactgagggaactg
gaaagtgtttcaatggatcccggcaacgagaaccctaaactccaagatctctcctttatc
ttgcaagaggagtaccacttaaacccagagagtagaaccatcctctttgtgaaaaccaga
gcacttgtggatgctttgaagaaatggattgaagaaaattctgaactcagctttctaaaa
cctggcatattgactggacgtggcaaaacaaatcagaacacagggatgacgctcccagcg
cagaagtgtgcgttggatgcattcagaaccgatggcgataagaagattctgattgccacc
tccgttgccgatgagggcatcgacattgcacagtgtaacttggtcatcctgtatgagtat
gtgggcaatgtcatcagaatgatccaaaccagaggcagaggaagagcaagaggtagcaag
tgcttccttctgaccagcaatgctgatgtaattgaaaaagaaaaaataaacatacataaa
gaaaaaatgatgaatgactccattttaaggcttcagacgtggaatgaagcagtatttaaa
gaaaaggttctccagatacagattcaagaaaaactcatcagggatagtcaaggaaaagta
gaacgtgtacctgataaggaaaataaaaaactgctctgcagaaagtgcaagggctttgcg
tgttacacagctgacatcagagtggtggaggactgccattacactgtggttggagatgat
tttaggaagtgctatgtgagtaaattacaccccaaaccaaagagctttgggtatttcgag
aagacagcaaagatcttctgttccagagaggactgcagccatgactggggaatccatgtg
aagtacaagacatttgagattccagttataaaaatagaaagctttgtggtggaagatatt
gctactggagctcagaaactatatgcaaagtggagggactttcctttgcagaagataccc
tttgatgctgcagaaatgtccaaatga

  All links  
Ontology (2)   
   KEGG BRITE (2)   
Pathway (10)   
   KEGG PATHWAY (10)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (20)   
   KEGG ORTHOLOGY (1)   
   RefGene (15)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (10)   
   Pfam (10)   
All databases (47)   

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