KEGG   Bos indicus (zebu cattle): 109553613
Entry
109553613         CDS       T04792                                 
Symbol
PKLR
Name
(RefSeq) pyruvate kinase PKLR isoform X1
  KO
K12406  pyruvate kinase isozymes R/L [EC:2.7.1.40]
Organism
biu  Bos indicus (zebu cattle)
Pathway
biu00010  Glycolysis / Gluconeogenesis
biu00620  Pyruvate metabolism
biu01100  Metabolic pathways
biu01200  Carbon metabolism
biu01230  Biosynthesis of amino acids
biu04910  Insulin signaling pathway
biu04930  Type II diabetes mellitus
biu04932  Non-alcoholic fatty liver disease
biu04950  Maturity onset diabetes of the young
Module
biu_M00001  Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate
biu_M00002  Glycolysis, core module involving three-carbon compounds
Brite
KEGG Orthology (KO) [BR:biu00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    109553613 (PKLR)
   00620 Pyruvate metabolism
    109553613 (PKLR)
 09150 Organismal Systems
  09152 Endocrine system
   04910 Insulin signaling pathway
    109553613 (PKLR)
 09160 Human Diseases
  09167 Endocrine and metabolic disease
   04930 Type II diabetes mellitus
    109553613 (PKLR)
   04950 Maturity onset diabetes of the young
    109553613 (PKLR)
   04932 Non-alcoholic fatty liver disease
    109553613 (PKLR)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:biu04147]
    109553613 (PKLR)
Enzymes [BR:biu01000]
 2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.1  Phosphotransferases with an alcohol group as acceptor
    2.7.1.40  pyruvate kinase
     109553613 (PKLR)
Exosome [BR:biu04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   109553613 (PKLR)
SSDB
Motif
Pfam: PK PK_C HpcH_HpaI IMPDH Neuregulin
Other DBs
NCBI-GeneID: 109553613
NCBI-ProteinID: XP_019809212
UniProt: A0A6P5B9I1
Position
3:16739268..16748559
AA seq 526 aa
MEQIPGDRQRQQLPATMADTFLEHLCLLDIDSEPVVARSTSIIATIGPASRSVERLKEMI
EAGMNIARLNFSHGSHEYHAESIANIREAVESFANSPLSYRPVAIALDTKGPEIRTGILQ
GDPASEVEIVKGSRVLVTVDPEFQTRGDANTVWVDYPNIVRVMPVGGRIYIDDGLISLVV
KKIGPEGLETEVENGGVLGSRKGVNLPGTQVDLPGLSEQDVQDLRFGVEHGVDIVFVSFV
RKASDVAAVRDALGPEGQGIKIVSKIENHEGVKKFNEILEVSDGIMVARGDLGIEIPAEK
VFLAQKMMIGRCNLAGKPVVCATQMLESMITKPRPTRAETSDVANAVLDGADCIMLSGET
AKGNFPVEAVKMQHAIAREAEAAVYHRQLFEELRRAAPLSRDPTEVTAIGAVEAAFKCCA
GAIIVLTTTGRSAQLLSRYRPRATVIAVTRSAQAARQAHLCRGVFPVLYREPPEDIWADD
VDRRVQFGIDNGKLCGFLSSGDLVIVVTGWQPGSGHTNIMRVLSVT
NT seq 1581 nt   +upstreamnt  +downstreamnt
atggagcagatccccggagacaggcagcggcagcagctgccagccactatggcagacacc
ttcctggaacatctgtgcctgctggacatcgactctgagcctgtggtcgctcgcagtacc
agtatcatcgccaccatcgggccggcatctcgctccgtggarcgtctcaaggagatgatc
gaggccgggatgaacatcgcgagactcaacttctcccacggctcccacgagtaccacgct
gagtccatcgctaacatccgggaggcggtggagagctttgcaaattctccgctcagctac
cgacccgtggccatcgccctggacaccaagggaccagagatacgcactgggatcctgcaa
ggggacccggcgtcagaagtggagatagtgaagggctcccgggtgctggtgaccgtggac
ccagagttccagacccgcggggacgcgaacaccgtgtgggtggactaccccaatatcgtc
cgagtcatgccggtggggggccgcatctacattgacgacgggctcatctccctagtggtc
aagaaaatcggtccrgaagggctagagaccgaagtggagaacggcggtgtcctgggcagt
cggaagggcgtgaacttgccaggcacccaggtggacctgcccgggctgtccgagcaagat
gtccaggacctgcgcttcggggtggagcatggcgtggacatcgtctttgtctctttcgtg
cggaaagccagcgacgtggctgccgtccgggatgctctggggccggaaggacagggcatc
aagatcgttagcaaaatcgagaaccacgagggcgtaaagaagttcaatgaaatcctggag
gtgagcgacggtattatggtggcacggggtgacctgggcattgagatcccggctgagaag
gttttcctggctcagaagatgatgatcggccgttgcaacttggcgggaaagcccgttgtc
tgtgctacacagatgctggagagcatgatcactaagccccggccaactcgggcagagacr
agtgacgtggccaatgctgttctggatggggcagactgcatcatgctgtcaggggagact
gccaaaggcaactttcctgtggaggctgtaaagatgcagcatgcgattgcccgggaggca
gaggctgccgtgtaccaccggcagctctttgaggagctacgccgggcagcaccactgagc
cgggatcccacggaggtcaccgctattggtgctgtggaggctgccttcaagtgctgtgct
ggtgccatcattgtgctgaccacaactggccgctcagcccagcttctgtcccggtaccga
cctcgggcaacagtcattgccgtcacccgctctgctcaggctgcccgccaggcccacctg
tgccgaggagtcttccctgtgctctaccgtgaacctccagaggacatctgggccgatgat
gtggaccgtcgggtccaatttggcatcgacaatggaaagctctgtggcttcctcagttct
ggggacctggtgattgtggtgacaggctggcaaccaggctcyggccataccaacatcatg
cgggtgctgagcgtaacctga

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (11)   
   KEGG PATHWAY (9)   
   KEGG MODULE (2)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (1)   
   KEGG REACTION (5)   
Genome (1)   
   KEGG GENOME (1)   
Gene (4)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
Protein domain (5)   
   Pfam (5)   
All databases (47)   

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