KEGG   Castor canadensis (American beaver): 109698715
Entry
109698715         CDS       T04791                                 
Name
(RefSeq) complement C3
  KO
K03990  complement component 3
Organism
ccan  Castor canadensis (American beaver)
Pathway
ccan04080  Neuroactive ligand-receptor interaction
ccan04145  Phagosome
ccan04610  Complement and coagulation cascades
ccan04613  Neutrophil extracellular trap formation
ccan04936  Alcoholic liver disease
ccan05133  Pertussis
ccan05134  Legionellosis
ccan05140  Leishmaniasis
ccan05142  Chagas disease
ccan05150  Staphylococcus aureus infection
ccan05152  Tuberculosis
ccan05167  Kaposi sarcoma-associated herpesvirus infection
ccan05168  Herpes simplex virus 1 infection
ccan05171  Coronavirus disease - COVID-19
ccan05203  Viral carcinogenesis
ccan05322  Systemic lupus erythematosus
Brite
KEGG Orthology (KO) [BR:ccan00001]
 09130 Environmental Information Processing
  09133 Signaling molecules and interaction
   04080 Neuroactive ligand-receptor interaction
    109698715
 09140 Cellular Processes
  09141 Transport and catabolism
   04145 Phagosome
    109698715
 09150 Organismal Systems
  09151 Immune system
   04610 Complement and coagulation cascades
    109698715
   04613 Neutrophil extracellular trap formation
    109698715
 09160 Human Diseases
  09161 Cancer: overview
   05203 Viral carcinogenesis
    109698715
  09172 Infectious disease: viral
   05171 Coronavirus disease - COVID-19
    109698715
   05168 Herpes simplex virus 1 infection
    109698715
   05167 Kaposi sarcoma-associated herpesvirus infection
    109698715
  09171 Infectious disease: bacterial
   05133 Pertussis
    109698715
   05134 Legionellosis
    109698715
   05150 Staphylococcus aureus infection
    109698715
   05152 Tuberculosis
    109698715
  09174 Infectious disease: parasitic
   05140 Leishmaniasis
    109698715
   05142 Chagas disease
    109698715
  09163 Immune disease
   05322 Systemic lupus erythematosus
    109698715
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    109698715
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:ccan01002]
    109698715
  09182 Protein families: genetic information processing
   04131 Membrane trafficking [BR:ccan04131]
    109698715
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:ccan04147]
    109698715
Peptidases and inhibitors [BR:ccan01002]
 Peptidase inhibitors
  Family I39: alpha2M family
   109698715
Membrane trafficking [BR:ccan04131]
 Endocytosis
  Phagocytosis
   Opsonins
    109698715
Exosome [BR:ccan04147]
 Exosomal proteins
  Exosomal proteins of other cancer cells
   109698715
SSDB
Motif
Pfam: TED_complement MG4 A2M_BRD A2M_recep MG1 NTR A2M C3_CUB2 MG2 MG3 ANATO C3_CUB1
Other DBs
NCBI-GeneID: 109698715
NCBI-ProteinID: XP_020038664
UniProt: A0A250YM82
Position
Unknown
AA seq 1662 aa
MGTASGPHLLLLLLASLSLALGDPMYSMICPNILRLENEETIVLEAHEVQDNVAVTVTVH
DFPAKKQVLSSEKTVLSSATGHLGNVTIKIPASNEFRSDKGRKFVTVQANFGATQVEKVV
LVSLQSGYLFIQTDKTIYTPGSTVLYRIFTVDHKLLPVGRTVIVTIETPEGIPIKRDTLS
SHNQYGILSLSWNIPELVNMGQWKIRAYYEHSPQQVFSAEFEVKEYVLPSFEVLVEPAEK
FYYIDDPKGLEVTITARFLYGKNVDGTAFVIFGVQDGDQRISLAQSLTRIVIEDGVGEAV
LKRQTLLEGVQPSRADALVGKSLYVSVTVILHSGSDMVEAEYNGIPIVTSPYQIHFTKTP
KYFKPAMPFDLMVFVTNPDGSPARRVPVVTQGNDVQSLTQDDGVAKLSINTPNSRQPLTI
TVRTKKEGIPEARQATKTMQAQPYSTMHNSNNYLHLSVPRVELKPGETLNVNFHLRTDAG
QEAKIRYYTYLVMNKGKLLKAGRQTREPGQDLVVLPLSITSDFIPSFRLVAYYTLIGASG
QREVVADSVWVDVKDSCVGTLVVKGGGKDDRQPLPGQQMTLKIEGDRGARVGLVAVDKGV
FVLNKKNKLTQSKIWDVVEKADVGCTPGSGQDYAGVFKDAGLAFKTSKGLQTAQRAETEC
SKPAARRRRSVQLMEKRMDKVGQYKSKELRKCCEDGMRDNPMRFTCQRRARFISQGEACV
KAFMDCCTYLAQLREQHRREGKLGLARSELDEDIIPEEDIISRSQFPESWLWTIEELKEP
EKNGISTKIMNIFLKDSITTWEILAVSLSDKKGICVADPYEITVMQDFFIDLRLPYSVVR
NEQVEIRAILYNYREKDSLKVRVELLHNPAFCSLATAKKRHYQTVVIPPKSSLPVPYVIV
PLTIGLQEVEVKAAVYNHFISDGVKKTLKVVPEGIRVNKTVAVRTLDPEHLGQEGVQRED
VPPADLSDQVPDTDSETKILLQGTPVAQITEDAVDGERLKHLIVTPSGCGEQNMIGMTPT
VIAVHYLDQTEQWEKFGLEKRQEALELIKKGYTQQLAFKQPSSAYAAFLNRAPSTWLTAY
VVKVFSLAVNLIAIDSQVLCGAVKWLILEKQKPDGVFQEDGPVIHQEMIGGYRNAKEADV
SLTAFVLIALQEAKDICEGQVNSLGGSITKAGDYLANSYMNLQRPYTVAIAGYALAQMGK
LEGPLQNKFLNTAKDRNRWEEPGHQLYNVEATSYGLLALLQLKDFDSVPPVVRWLNEQRY
YGGGYGSTQATFMVYQALAQYQTDVPDHKDLNMEVAINLPSRSSLVKFRLLWESGKLLRS
EETKQNEGFLLTAKGKGQGTLSVVTMYHAKVKGKVTCKKFDLRVTIRPAPETVKKPQDAK
SSMVLDICTRYLGDEDATMSILDISMMTGFVPDTSDLELLSTGVDRYISKYELSKAFSNK
NTLIIYLDKISHSEEECLSFKVHQYFNVGLIQPGSVKVYSYYNLEETCTQFYHPEKEDGM
LSKLCHKDMCRCAEENCFMHQMDEKITLNERLDKACEPGVDYVYKTKLATIELSDDFDEY
VMVIEQVIKSGSDEVQAGQERRFISHIKCREALKLQQGKHYLMWGLSSDLWGEKPNTSYI
IGKDTWVELWPDAEECQDEENQKQCQDLGAFTESMVVFGCPN
NT seq 4989 nt   +upstreamnt  +downstreamnt
atggggactgcctcaggcccccacctgctgctcttgctgctggccagcctctccctggcc
ctgggggatcccatgtactccatgatctgccccaatatcctgcggctggagaatgaggag
accatagtgctggaggcccacgaagtgcaagacaacgttgcagtcacagtcactgtccac
gacttcccggccaagaagcaagtgctatccagtgagaagactgtgctctccagcgccaca
ggacacttgggcaatgtcaccatcaagatccctgccagcaacgagttcagatcagacaaa
gggcgcaagttcgtgacagtgcaggcaaacttcggggctacgcaggtggagaaagtggtg
ctggtcagccttcagagcgggtacctcttcatccagacagacaagaccatctacaccccg
ggctccacagtcctctatcggatcttcaccgttgaccacaagctgctgcccgtgggccgg
actgttatcgtcaccattgagaccccagaaggcatccccatcaagcgagacactctgtct
tctcacaaccagtatggcatcttgtccctgtcttggaacatcccagagctggtcaacatg
gggcagtggaagatccgagcctactacgaacactccccgcagcaggtcttctctgctgag
tttgaggtgaaggagtatgtgctgcccagtttcgaggtcctggtggagcccgctgagaaa
ttctactacattgatgaccccaagggcctggaagtcaccatcaccgccaggttcttatat
gggaagaacgtggatggaacagcttttgtcatctttggggtccaggatggcgaccaaagg
atttctctggcccagtccctcacccgcattgtgatcgaagacggtgttggggaggctgta
ctgaaacgacagacgctactggaaggggtgcagccctccagggctgatgccctggtgggg
aagtccttgtacgtgtctgtcactgtcattttgcactcaggcagtgacatggtggaagca
gagtacaacggaatccccatcgtgacctctccataccagatccacttcaccaagacaccc
aagtacttcaagccagccatgccctttgatctcatggtgtttgtgacaaaccccgacggc
tccccggcccgccgtgtacccgtggtgacccagggcaatgacgtgcagtctctcacccaa
gacgatggtgtggccaaactaagcatcaacacgcccaacagtcggcagcccctcaccatc
acggtgcgcaccaagaaggaggggatcccggaggcacggcaagccaccaagacgatgcag
gcccagccctacagtacaatgcacaattccaacaactacctacatctctccgtgcctcgt
gtcgagctgaagccaggagagaccctcaatgtcaacttccacctgcgcacagatgctggc
caggaagccaagatccgttactacacctacctggtcatgaacaaggggaagctgctgaag
gcaggtcgccaaactagagagcccggccaggacctggtggtcctacctttgagcatcact
tcggatttcattccttctttccgcctggtggcttattacacgctgattggtgccagcggc
cagagggaggtggtggccgactctgtgtgggttgatgtgaaagattcttgtgtgggcacg
ctggtggtaaaaggtggcgggaaagatgatcggcagcctctacctgggcagcagatgacc
ctcaagatagagggtgaccgtggggcccgcgtggggctggtggctgtggacaagggcgtg
tttgtgctgaacaaaaagaataagctgactcagagtaagatttgggatgtggtggagaag
gcagacgttggctgcacccctggcagtgggcaggactatgcgggtgtcttcaaggatgca
ggtctggccttcaagaccagcaaaggcctgcagaccgcccagagggcagaaaccgagtgc
tcaaagccagccgcccgccgccgccgctctgtgcagctcatggagaagaggatggacaaa
gttggtcagtacaagagcaaggagctgcggaagtgctgcgaggacggtatgcgtgacaac
ccgatgcggttcacctgccagcgccgagctcgcttcatctcccagggggaggcgtgcgtg
aaggccttcatggactgctgcacctacctcgcccaactgcgcgagcagcaccggcgcgag
ggcaagctgggcctggccaggagtgagctggatgaggacatcattccagaagaagacatc
atatctaggagccagtttccagaaagctggctgtggaccatagaagaactgaaagaacca
gagaagaatggaatctccacgaagatcatgaacatctttctgaaagacagcatcaccacg
tgggagatcctggctgtgagcttgtcagacaagaaagggatctgtgtggcagacccctac
gagatcacggtgatgcaggacttcttcatcgacctgcggctcccctattcggtggtgcgc
aatgagcaggtggagatccgagccatcctctacaactatcgtgaaaaggacagcctcaag
gtgagggttgaactgctccacaacccagccttctgcagcctggccaccgccaagaagcgc
cactaccagaccgtggtcatcccgcccaagtcctcgctgcccgtgccttatgtcatcgtg
cccttgactatcggcctgcaggaggtggaggtcaaggccgcggtctacaaccacttcatc
agcgacggtgtcaagaagaccctgaaggtcgtgcctgaaggaatcagagtgaacaaaaca
gtggccgttcgcacgctggatccagaacaccttggccaagagggagtgcagagagaggat
gtgccaccagcagacctcagcgaccaagtcccagacaccgattctgagaccaagattctc
ctgcaagggaccccggtggcccagattacagaggacgctgtggatggggagcgcctgaag
catctcattgtgaccccctcgggctgcggggaacagaacatgatcggcatgacgcccacc
gtcatcgctgtgcactacctggaccaaactgagcagtgggagaagtttggcctggagaag
cggcaggaggccctggagctcattaagaaagggtacacccagcagctagccttcaaacaa
cccagctcggcctatgctgccttcctgaaccgcgcacccagcacctggctgacagcctat
gtggtcaaggtcttctctctggcggtcaacctcattgccatcgactcccaagtcctctgt
ggggctgttaaatggctgatcttggagaagcagaagcccgacggagtcttccaagaggat
gggcccgtgatacatcaagaaatgattggtggctaccggaatgccaaggaagctgatgtg
tccctcaccgccttcgtcctcatcgcccttcaggaagctaaagatatttgcgaggggcag
gtcaacagcctaggaggcagcatcaccaaagcaggagactaccttgcgaacagttacatg
aacctgcagaggccgtacactgtggccattgccggctatgccctggcacagatgggcaag
ctggagggccccctccaaaataagtttctaaacacggccaaagatcggaaccgctgggag
gagccgggtcatcagctttacaatgtggaggcgacatcctatggcctcctggccctgctg
cagctcaaagactttgacagtgtgcctcccgtcgtgcgctggctcaatgagcagagatac
tatggtggcggctatggctccacccaggccaccttcatggtgtaccaagccttggcccaa
taccaaacagacgtccctgaccacaaggacttgaacatggaggtggccatcaacttgccc
agccgcagctccctggtcaaatttcgccttctctgggaatctggtaaactcctgcggtca
gaagagaccaagcaaaatgagggcttcttgttaacagctaaagggaaaggccaaggtacc
ctctcggtggtgaccatgtaccatgccaaagtcaaaggcaaagtcacctgcaagaaattt
gacctgagggtcaccataagaccagcccctgaaacagtaaaaaagccccaggatgccaag
agctctatggtcctggatatctgcacgaggtacctgggagatgaggatgccaccatgtcc
atcctggatatatccatgatgactggcttcgttcctgacacaagtgaccttgagctgctg
agcactggcgtggacaggtacatctccaagtatgagctgagcaaagccttctccaacaag
aacaccctcatcatctacctggacaagatctcacactccgaggaagaatgtctgtccttc
aaagtccaccagtactttaacgtggggctcatccagcccgggtccgtcaaagtctactcc
tactacaacctggaggaaacctgtacccagttctaccaccctgagaaggaagatggtatg
ctgagcaagctgtgccacaaggacatgtgtcgctgtgcagaggagaactgcttcatgcac
cagatggacgagaagatcaccctcaatgaacggctggacaaggcctgtgagcccggagtg
gactatgtgtacaagaccaagctggctaccatcgagctgtcagatgactttgatgaatat
gtaatggtcatcgaacaggtcatcaagtcaggctccgatgaggtgcaggcagggcaggaa
cgcaggttcatcagccacatcaagtgcagagaagccctgaagctgcagcaagggaagcac
tacctcatgtggggtctgtcctctgacctctggggagaaaaacccaacaccagctacatc
atcgggaaggacacgtgggtggagctctggcctgacgcagaggaatgccaagatgaggag
aaccagaaacagtgccaggaccttggcgccttcaccgagagcatggtggtctttggttgc
cccaactaa

  All links  
Ontology (4)   
   KEGG BRITE (4)   
Pathway (16)   
   KEGG PATHWAY (16)   
Genome (1)   
   KEGG GENOME (1)   
Gene (15)   
   KEGG ORTHOLOGY (1)   
   RefGene (11)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (2)   
   UniProt (1)   
   RefSeq(pep) (1)   
DNA sequence (3)   
   RefSeq(nuc) (1)   
   GenBank (1)   
   EMBL (1)   
Protein domain (12)   
   Pfam (12)   
All databases (53)   

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