KEGG   Caenorhabditis elegans (nematode): CELE_K12H4.8
Entry
CELE_K12H4.8      CDS       T00019                                 
Symbol
dcr-1
Name
(RefSeq) Death-promoting deoxyribonuclease
  KO
K11592  endoribonuclease Dicer [EC:3.1.26.-]
Organism
cel  Caenorhabditis elegans (nematode)
Brite
KEGG Orthology (KO) [BR:cel00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:cel03036]
    CELE_K12H4.8 (dcr-1)
Chromosome and associated proteins [BR:cel03036]
 Eukaryotic type
  Gene silencing
   RISC (RNA-induced silencing complex)
    CELE_K12H4.8 (dcr-1)
   microRNA pathway
    RISC loading complex
     CELE_K12H4.8 (dcr-1)
SSDB
Motif
Pfam: Ribonuclease_3 Dicer_dsRBD Ribonucleas_3_3 Dicer_dimer Dicer_platform PAZ Helicase_C ResIII DEAD Dicer_PBD Cas3-like_C_2 dsrm SLFN-g3_helicase
Other DBs
NCBI-GeneID: 176138
NCBI-ProteinID: NP_498761
WormBase: WBGene00000939
Ensembl: WBGene00000939
UniProt: P34529
Position
III:complement(8071967..8080281)
AA seq 1910 aa
MVRVRADLQCFNPRDYQVELLDKATKKNTIVQLGTGSGKTFIAVLLLKEYGVQLFAPLDQ
GGKRAFFVVEKVNLVEQQAIHIEVHTSFKVGQVHGQTSSGLWDSKEQCDQFMKRHHVVVI
TAQCLLDLIRHAYLKIEDMCVLIFDECHHALGSQHPYRSIMVDYKLLKKDKPVPRVLGLT
ASLIKAKVAPEKLMEQLKKLESAMDSVIETASDLVSLSKYGAKPYEVVIICKDFEIGCLG
IPNFDTVIEIFDETVAFVNTTTEFHPDLDLDPRRPIKDSLKTTRAVFRQLGPWAAWRTAQ
VWEKELGKIIKSQVLPDKTLRFLNMAKTSMITIKRLLEPEMKKIKSIEALRPYVPQRVIR
LFEILETFNPEFQKERMKLEKAEHLSAIIFVDQRYIAYSLLLMMRHIKSWEPKFKFVNPD
YVVGASGRNLASSDSQGLHKRQTEVLRRFHRNEINCLIATSVLEEGVDVKQCNLVIKFDR
PLDMRSYVQSKGRARRAGSRYVITVEEKDTAACDSDLKDFQQIEKILLSRHRTVNNPIED
DSDRFEEFDVDSQMEPYVVEKTGATLKMSTAIALINRYCSKLPSDIFTRLVPHNQIIPIE
ENGVTKYCAELLLPINSPIKHAIVLKNPMPNKKTAQMAVALEACRQLHLEGELDDNLLPK
GRESIAKLLEHIDEEPDEYAPGIAAKVGSSKRKQLYDKKIARALNESFVEADKECFIYAF
ELERFREAELTLNPKRRKFEDPFNYEYCFGFLSAKEIPKIPPFPVFLRQGNMKVRLIVAP
KKTTVTAAQLQEIQLFHNYLFTQVLQMCKTGNLEFDGTSNAPLNTLIVPLNKRKDDMSYT
INMKYVSEVVANMENMPRIPKDEVRRQYKFNAEDYKDAIVMPWYRNLEQPVFYYVAEILP
EWRPSSKFPDTHFETFNEYFIKKYKLEIYDQNQSLLDVDFTSTRLNLLQPRIQNQPRRSR
TVSNSSTSNIPQASASDSKESNTSVPHSSQRQILVPELMDIHPISATLWNVIAALPSIFY
RVNQLLLTDELRETILVKAFGKEKTKLDDNVEWNSLAYATEYEEKQTIIVKKIQQLRDLN
QKSIEDQERETRENDKIDDGEELFNIGVWDPEEAVRIGVEISSRDDRMDGEDQDTVGLTQ
GLHDGNISDEDDELPFVMHDYTARLTSNRNGIGAWSGSESIVPSGWGDWDGPEPDNSPMP
FQILGGPGGLNVQALMADVGRVFDPSTASSSLSQTVQESTVSPPKQLTKEEEQFKKLQND
LLKQAKERLEALEMSEDMEKPRRLEDTVNLEDYGDDQENQEDENTPTNFPKTIDEEIEEL
SIGARKKQEIDDNAAKTDVLERENCEVLPVAINEKSRSFSFEKESKAINGRLIRQRSEEY
VSHIDSDIGLGVSPCLLLTALTTSNAADGMSLERFETIGDSFLKFATTDYLYHTLLDQHE
GKLSFARSKEVSNCNLYRLGKKLGIPQLIVANKFDAHDSWLPPCYIPTCDFKAPNTDDAE
EKDNEIERILDGQVIEEKPENKTGWDIGGDVSKSTTDGIETITFPKQARVGNDDISPLPY
NLLTQQHISDKSIADAVEALIGVHLLTLGPNPTLKVMNWMGLKVIQKDQKSDVPSPLLRF
IDTPTNPNASLNFLNNLWQQFQFTQLEEKIGYRFKERAYLVQAFTHASYINNRVTGCYQR
LEFLGDAVLDYMITRYLFEDSRQYSPGVLTDLRSALVNNTIFASLAVKFEFQKHFIAMCP
GLYHMIEKFVKLCSERNFDTNFNAEMYMVTTEEEIDEGQEEDIEVPKAMGDIFESVAGAI
YLDSGRNLDTTWQVIFHMMRGTIELCCANPPRSPIRELMEFEQSKVRFSKMERILESGKV
RVTVEVVNNMRFTGMGRNYRIAKATAAKRALKYLHQIEQQRRQSPSLTTV
NT seq 5733 nt   +upstreamnt  +downstreamnt
atggtcagggtaagagctgatttacaatgttttaaccccagggactaccaggtggaactt
ttggataaagcgacaaaaaagaacacaatcgtccaactaggcactggttcaggaaaaact
ttcattgcagttctactgctgaaagaatatggagttcaattgtttgcaccattggatcag
ggtggaaaacgagcgttttttgttgtagagaaagtaaacctcgttgaacaacaagctatc
cacatcgaagttcacacaagtttcaaagttggtcaggtccacggacagacaagtagtggt
ttatgggacagcaaagaacaatgtgatcagttcatgaagaggcaccatgttgttgtgatc
acagctcaatgccttcttgatttgattcgacatgcgtacttgaaaattgaagacatgtgt
gttctgatctttgacgaatgtcatcatgctctcggttctcaacatccatacagaagcatc
atggtcgattataagttattgaaaaaggacaaacccgtcccacgtgtattaggactcaca
gccagtcttatcaaagcgaaagttgcgccggaaaaactaatggaacagttaaaaaagttg
gaatctgcgatggacagtgttatagagacagctagtgatttagtctcgctctcgaaatac
ggtgcgaaaccctatgaagttgtgatcatctgcaaagactttgaaattgggtgcctgggt
attccgaatttcgacacagttatagaaatatttgatgaaactgtagcctttgtgaacacc
acaacagaatttcatccagatctagatttggatcctcgtagaccgattaaagattctctc
aagacgacgcgagctgtttttcgtcaactgggaccttgggcggcatggcgaacggctcaa
gtttgggagaaagagttgggaaaaattataaaatctcaagtgctaccggataagacgttg
cggtttttgaatatggcaaaaacatctatgattacgattaaaagattgttggaaccggag
atgaagaaaatcaaaagtattgaagctctccgtccatatgttcctcaacgtgtcatacgt
cttttcgaaatcctagaaactttcaaccccgaatttcaaaaagaacgaatgaagttagaa
aaagcagaacatttatcagccattatttttgtcgatcaacggtacattgcatattcgtta
cttcttatgatgcgtcatattaaatcatgggagcctaagttcaagtttgtgaacccggat
tacgtcgttggagccagcggacgaaatttggcgagttcggatagtcaaggattacataaa
cgacaaactgaagttcttcgccgtttccatcgaaatgaaatcaattgtcttatcgctaca
tcagtgcttgaagaaggtgtagatgttaaacaatgtaatcttgtgattaaatttgatcga
ccacttgacatgagatcatacgttcagtcaaagggaagagctcggcgagctggatcaaga
tatgttatcactgttgaggagaaagatactgcggcgtgtgatagtgatttgaaagatttc
cagcaaatagaaaaaattcttcttagccgccatcgtacagtcaacaatcctattgaagat
gattcggatagatttgaagaatttgatgttgattctcaaatggaaccatatgttgttgaa
aaaactggtgcaacattgaaaatgtcaactgctatcgcattaattaatagatattgttcg
aagcttccttccgatatcttcactcgtcttgttccacacaatcaaatcattccaattgaa
gagaatggagtgaccaaatactgtgcagagcttcttcttccaattaactcaccgatcaaa
catgcaattgtgctcaaaaatccaatgccaaataagaagactgcacagatggcagttgca
cttgaagcatgtcgacaattacatttagaaggagaactcgatgataatttacttccaaaa
ggaagagagtcgattgccaaattattagaacatattgatgaggagccggatgagtatgca
cctggaattgctgctaaagttggatcatcaaaacgaaagcaattatatgacaaaaagatt
gctcgtgctctcaatgaatccttcgtggaagcagataaggaatgtttcatctatgcattc
gaattggaacgtttccgggaagccgaacttacgttgaacccgaaaagacgaaagtttgaa
gatccatttaattatgaatattgcttcggatttctgagcgcaaaagagataccaaagatc
ccaccattcccagtgtttcttcgacaaggaaatatgaaagtccgattgattgtcgcaccg
aaaaagactaccgtaaccgctgctcagcttcaagagattcaactgttccataattatttg
ttcacacaagttcttcaaatgtgtaaaacgggaaatttggaattcgatggaacatcaaat
gcaccattgaacacgttgattgttccacttaacaagcgaaaagatgatatgtcctacaca
atcaacatgaaatatgtatcggaagtagttgcaaacatggaaaatatgccacgtattcca
aaagatgaagttcgtcgtcaatacaaattcaacgctgaagattataaggatgcgatcgta
atgccgtggtatcgaaatctggaacagcctgtattctactatgttgctgaaattctacca
gaatggaggccgtcgtcgaaattcccggatacgcacttcgaaacgtttaacgagtatttc
atcaagaaatataaattagagatttatgatcagaatcaaagtttattggatgtagatttc
acatctactcgtcttaaccttcttcaacctcgaattcaaaatcaaccacgtcgttcaaga
actgtgagtaactcctcaacgtcaaatattcctcaagcatctgcttctgattcaaaagag
tcgaatacttccgttccacactcttcacaacgtcagatccttgtaccggaattgatggac
attcatcctatctctgcgactctttggaatgttatagcagccctgccaagtattttctat
cgtgttaatcagttattgttgactgatgaacttcgagaaacaattttggtgaaagctttt
ggaaaagagaaaactaaactggatgataatgttgaatggaattctctggcatatgcaacc
gaatatgaagagaaacaaacgataatcgttaagaaaattcaacaattgagagatttaaat
caaaaatcgattgaagatcaagaaagagagacgagagaaaatgataagattgacgatggt
gaggagttattcaatattggagtttgggatccagaagaggcagtcagaattggtgtagaa
attagttcaagagatgatagaatggacggtgaagatcaggatactgtaggactaacacaa
ggacttcatgatgggaatatatccgatgaagacgatgaactgccgtttgtaatgcatgat
tacacagccaggctcacttctaacagaaatggaattggtgcatggtcaggatctgagtct
attgttccaagcggatggggagattgggatggacctgaaccagataatagtcccatgcct
ttccaaattctcggtggaccaggtggtttgaatgtgcaggcactgatggctgatgtcgga
agagtttttgatccatctactgcttcgtcttccctttctcaaactgtacaagaatcgaca
gtttcacctccaaaacaattgacaaaagaagaagaacagtttaagaaacttcaaaatgac
ttgctgaaacaagcaaaagagcgacttgaagctctagaaatgtcagaagatatggagaaa
ccgcgaagattggaggatactgtgaatttagaagattatggagatgatcaagaaaatcaa
gaggatgagaatacaccaacaaatttcccgaaaaccatagatgaagaaattgaagagttg
tcaattggagcccggaaaaaacaagaaatagacgacaatgcagctaaaactgatgtactc
gaaagggaaaactgtgaagttttgccagttgctataaatgaaaagtctcgttcattctct
tttgaaaaagaaagtaaagcaataaatggacgacttataagacaacgatcagaggaatac
gtgtcacatattgattcagatattggattaggagtatctccatgtcttttgttaactgct
cttactacttccaatgctgcagatggaatgtcattagagagattcgaaacaatcggagac
tctttcttgaagtttgctactaccgattatctctatcacacgttgcttgatcaacatgaa
ggaaaattgtcgtttgcacgtagtaaagaagtttcaaattgcaatttgtatcgactgggc
aagaaattgggaatacctcaattgattgttgcaaataaattcgatgctcacgattcttgg
ctgccaccatgctatattccaacttgcgacttcaaagctcctaacactgatgatgcagaa
gagaaagataatgaaattgaacgaattttggatggacaagtgattgaagagaaacctgaa
aataaaactggatgggacattggtggtgatgtctcgaaaagcactaccgatggaatagag
actattacattcccaaagcaagcccgtgttggtaatgatgatatctctccacttccttac
aacttgctcacccaacagcatatttcggataaatcaatcgctgacgcagtcgaagctttg
atcggagtacatttgctgacgttgggacctaatccaacgctgaaggtgatgaattggatg
ggactgaaagtaattcaaaaagatcagaagagtgacgtaccttcacctcttctacgattc
attgacactccgaccaatccgaatgcttctctaaatttcttgaacaatttgtggcagcaa
ttccagtttacacaattggaagagaaaattggatatcgcttcaaggaacgtgcttatctt
gttcaagctttcacacatgcttcgtacatcaataatcgtgtcacaggatgctatcaaaga
ttagaattcctcggagacgctgttctcgactatatgatcaccagatatttgtttgaagat
tctcgtcaatacagtccgggtgttctcactgatttacgatcagctctcgtcaataataca
attttcgcgtcgttagcagtgaaattcgagtttcaaaagcacttcatcgctatgtgccca
gggctttatcacatgattgagaaatttgttaagctgtgctcggagcgcaatttcgatact
aatttcaatgctgagatgtatatggtgactactgaggaagaaatagatgaaggccaagaa
gaggatattgaagttccaaaagcgatgggtgacatatttgaatcagtagctggcgccatt
tatctcgactctggacgtaatttggataccacttggcaagtgattttccacatgatgcgc
gggactattgaattgtgctgtgcgaacccaccaagatcaccgattcgagagcttatggag
ttcgagcagagcaaagttcgattcagtaaaatggaacgaattctcgagagtggaaaagtt
cgagttacagtcgaggttgttaataacatgagattcactggaatgggaaggaactatcga
atcgcgaaagctactgctgcgaaaagagctttgaaatacctccatcaaattgagcagcaa
agaagacaaagcccatcattaacaactgtttaa

  All links  
Gene (62)   
   RefGene (57)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   WORMBASE (1)   
Protein sequence (3)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (1)   
   RefSeq(nuc) (1)   
Protein domain (13)   
   Pfam (13)   
All databases (79)   

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