KEGG   Canis lupus familiaris (dog): 100630922
Entry
100630922         CDS       T01007                                 
Symbol
ADAMTS13
Name
(RefSeq) A disintegrin and metalloproteinase with thrombospondin motifs 13
  KO
K08627  a disintegrin and metalloproteinase with thrombospondin motifs 13 [EC:3.4.24.87]
Organism
cfa  Canis lupus familiaris (dog)
Pathway
cfa04611  Platelet activation
Brite
KEGG Orthology (KO) [BR:cfa00001]
 09150 Organismal Systems
  09151 Immune system
   04611 Platelet activation
    100630922 (ADAMTS13)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors [BR:cfa01002]
    100630922 (ADAMTS13)
Enzymes [BR:cfa01000]
 3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.24  Metalloendopeptidases
    3.4.24.87  ADAMTS13 endopeptidase
     100630922 (ADAMTS13)
Peptidases and inhibitors [BR:cfa01002]
 Metallo peptidases
  Family M12: astacin/adamalysin family
   100630922 (ADAMTS13)
SSDB
Motif
Pfam: ADAMTS_CR_3 ADAMTS_spacer1 TSP1_ADAMTS ADAMTS_CR_2 TSP_1 Reprolysin Reprolysin_4 Reprolysin_3 TSP1_spondin Reprolysin_5 Peptidase_M10 TSP1_CCN TSP1_CFP_C Reprolysin_2 DUF4953
Other DBs
NCBI-GeneID: 100630922
NCBI-ProteinID: NP_001229641
Ensembl: ENSCAFG00000019776
VGNC: 37592
UniProt: F7J124
Position
9:49120490..49148471
AA seq 1502 aa
MREPRPWGRCVGAILTSVFFLLGCWGLSDFQQQFLQALDPEEVTSYFGPEATLKAPPFDV
APLSCICEDGTGVPPCRALSCSLHIWGQLFTISFPPEWSLFTTSFTSELVLNASLQLLRR
LPHLCFLGGRPLLPLGAAARVTYCSGHLEGDILVGADLFYIQPVKMQHRELVPPWALAQP
HLIHRPFPKAPTAPKALNTIREASLSAPLPPSPGRPRSPRLRRWVAGSVLHLELLVAVGP
DVYQAHQEDTERYVLTNLNMGSELLRDPSLGAQFQVHLVKMVILTQPEDAPNITANITAS
LLSVCEWSRTVNPEDDTDPGHADLVLYITRFDLELPDGNRQVRGVTQLGGACSSSWSCVI
TEDTGFDLGVTIAHEIGHSLGLEHDGATGSGCKPSGHVMGSQDRAAARGDLLWSACSRQQ
LLHLLSTGRLRCLGDLPEPQAGASGRLPQAQPGLLYGMDEQCRVAFGAGAVACTFTREHL
DMCQALSCHTDPLDQSSCSRLLIPLLDGTECGVQKWCSKGHCRSLAELSPVGVVHGQWSS
WSPPSLCSRSCGGGVVTRRRHCNNPRPAFGGHVCVGADLQAEMCNTQACEKTQLEFMSEQ
CSQTDRKPLYLTPGNASFYRWGSAEQYSQGDALCRHMCRAIGEAFIVRRGESFLDGTRCV
PSGQREDGTLSLCMLGSCKTFGCDGRMDSQQVRDVCQVCGGDNSTCSPQNGSFTAGRARE
YVTFLTVTRNLTSVHITNRRPLFTHLAVRIRGHYIVAGNSSISPSTTYPSLLEDSRVEYR
VTLTKDRLPHLEEISIRGPTQEDMEIQVYRRYGEEYGDLARPDITFTYFEPKQPQAWAWV
AVRGSCSVSCGAGRRWVTYSCLDQARNVWVEAARCEGSQQPAAWSESCTPRPCPPQQEAS
DACTTACGADLASQNVTCVHRVAGLETLATAGPCSTDEKLPALKPCVATACPPGQGYPDL
QSLEEEKEATSPSGSAGLRARTTHMWTPLAGPCSASCGQGLTELNFMCMDSALGTPVREE
LCDLESKPGSRQEVCQAAPCPAWWRYKLAACSVSCGGGFAQRMLYCARAHGEDEDEEILP
DTQCQGLPRPEQQEACSPEPCPPRWKIMSLGPCSASCGFGTATRSVACVQLSQGQDIEVD
GAACAALVRPQASIPCILAYCTYRWHVSTWTQCSVSCGDGIQRRRKACLGPQAQAPVLAD
FCQHLHKPATVRGCWAGPCGGQVTPRPAPNEEATAPDQATAGASPEWPQPQAHLLSPAPP
LQRLLPGSQENPAESSACGRQHLEPMGTIDMRGPGRADCAVAIGRPLGEVVTLQVLESSL
SCSAGDVLLLWDRLTWKKMCGKLSGMTFSSKTNTLVVRQRRVRLEGGVVLRYRSRPAPGA
PHRECDMQLFGPWGEIVSPSVGADGRNSGGCRIFINVAPQARIAIHALATDGTGTGASYV
LIRDIHSLKTMTFRGQQALYWESEGSQAEMEFSQGFLEAHASLRGQYWTLQSRVQEPGWA
EP
NT seq 4509 nt   +upstreamnt  +downstreamnt
atgagggagcctcgcccctgggggagatgtgtgggggcaattctcacatctgtcttcttt
ctcctgggctgctggggactctccgatttccagcagcaatttcttcaggctttggacccg
gaggaagtgacttcttattttggccctgaagctaccctaaaagcacccccatttgacgtg
gccccgctcagctgcatctgtgaagatggaaccggggtacctccctgccgggccctgagc
tgctccctgcacatctggggacagctcttcaccatctccttcccgcctgaatggagcctc
tttaccacctccttcaccagtgagctcgtcctgaacgcctccctccagctcctcaggcgg
ctgccccatctctgcttcttggggggccgccccctgctgcccctgggggccgcggccagg
gtcacttactgctcaggccacttggagggtgacatcctggtgggtgcagacctgttctac
atccagccagtgaagatgcagcaccgggagctggtgccaccctgggctcttgcccagccc
cacctgatccacaggcctttccccaaggcccccacggcccccaaggcccttaacaccatc
cgagaagcttcgctgtcagccccgcttcctccctcaccaggccgtcctcggtcccctcgc
ctccggagatgggttgctgggagtgtcttacacctggagctgctggtggccgtgggcccc
gacgtctatcaggctcaccaggaggacactgagcgttatgtgctcactaacctcaacatg
gggtcagagctgctgagggacccatccctgggggctcagttccaagtgcatctggtgaaa
atggtcattctgacccagcccgaggatgctccgaacatcacggccaacatcacggcatca
ctgctgagtgtctgtgagtggagcaggacagtcaaccctgaggacgacacagatcctggc
catgccgacctggttctctacatcaccagatttgacctggagttgcctgatggtaaccgg
caggttcggggagtcacccagctggggggtgcttgctcatcttcctggagctgtgtcatc
actgaggatactggctttgacctgggggtcaccatcgctcatgagattggtcacagcctg
ggcctggagcacgacggcgcgaccggcagcggctgcaagcccagcggccatgtgatgggc
tcccaggaccgagcggccgcccgtggggacctcttgtggtctgcctgcagccgccagcaa
ctgctgcatctgctcagcacaggacggttgcgctgcctgggggacctgccagagccacag
gctggggcctccgggcgccttcctcaggcacagcctggcctcctgtacggcatggacgag
cagtgccgggtcgccttcggcgctggggcagtggcctgcaccttcaccagggagcatctc
gacatgtgccaggctctgtcctgccacacggatcccctggaccaaagcagctgtagccgc
ctcctcatccctctcctggatgggacagagtgcggcgtgcagaagtggtgctccaagggt
cactgccgctccctggcagagctgagcccagtgggggtagtgcatgggcagtggtctagc
tggagtccccccagcctttgctcccgctcctgcggaggaggtgtggtcaccaggaggcgg
cactgcaacaaccccaggcctgcctttggagggcatgtgtgcgtgggtgctgacctccag
gcggagatgtgcaacacccaggcctgtgagaagacccagctggagttcatgtctgagcag
tgctcgcagacggacaggaaaccgctctacctgaccccggggaatgcctccttctaccgc
tggggctccgctgagcagtacagtcaaggggatgccctgtgcagacacatgtgccgggcc
attggcgaggccttcattgtgaggcgtggggaaagtttcctagatgggacccggtgtgtg
ccaagtggtcagcgggaggacgggaccctgagcttgtgcatgttgggcagctgcaagaca
ttcggctgtgatggcaggatggactcccaacaggtgcgagacgtgtgccaggtgtgcgga
ggggacaacagcacctgcagcccacagaacggctctttcacagctggaagggccagagaa
tatgtcacattcttgacagttacccgcaacctgaccagtgtacacatcaccaaccggagg
cctctcttcacacacttggcggtgcggatccgagggcactacatcgtggctgggaattct
agcatctctcccagcaccacctacccctccctcctggaggacagccgtgtggagtacaga
gtgaccctcaccaaggaccggctgcctcacctggaggagatctccatccggggacccacc
caggaagacatggagatccaggtttacaggcgctacggggaggagtatggtgaccttgca
cgcccagacatcaccttcacctacttcgagcctaagcagccacaggcctgggcctgggtc
gccgtgcgggggtcctgctcggtgagctgtggggcagggcggcgctgggtgacctacagc
tgtctggaccaggccaggaacgtgtgggtggaggctgcccggtgcgaagggagccagcag
ccagcagcgtggtcagagtcctgcacccccaggccctgccccccacagcaggaggcatcg
gatgcatgcacaacagcctgtggagcagacctggcatcacagaatgtgacgtgtgtgcac
agggtagctggcctggagacactggccacggctggaccctgctccacagatgagaagctg
cctgccctcaagccctgtgtggccacggcatgtcctccgggacagggttatccagacctc
cagtctctggaggaggagaaggaggccacatccccatcaggaagtgctgggctgagggct
cgcaccacacacatgtggacccccctggcagggccatgctctgcctcctgtggtcaaggc
ctgacagagctgaacttcatgtgtatggactctgccctgggaacccctgtccgggaagag
ctatgtgacctggaaagcaagcctgggagccggcaggaggtctgccaggctgccccatgc
ccggcttggtggaggtacaagctggccgcatgcagtgtgagctgtggaggagggtttgcg
cagaggatgctatattgtgcacgggctcacggggaggacgaggacgaggagatcctgcca
gatacccagtgccaggggctgcctcgtccagagcagcaggaagcctgcagcccagagccc
tgcccacccaggtggaaaatcatgtccctcggcccatgctcagccagctgtggctttggc
actgccacacgttctgtggcctgtgtgcagctcagccaaggccaggacattgaggtggat
ggggcagcctgtgcggctctggttcggcctcaggccagcatcccctgcatcctcgcctat
tgcacctaccggtggcatgtcagcacctggacacagtgctctgtctcctgcggagatggc
atacagcgcaggcgtaaggcctgccttggaccccaggcccaggcacctgtgctggctgac
ttctgccagcacttgcacaagccagccactgtgcggggctgctgggccgggccctgtggt
gggcaggtgactcccaggccagcacccaacgaggaagccactgctccagaccaggccact
gctggtgcctctccggagtggcctcagccccaggcccaccttctatccccagcacccccg
cttcagaggcttctgcctgggtctcaggaaaacccagctgagtccagtgcctgtggccgg
cagcatcttgagccaatgggaactattgacatgcgaggcccagggcgggctgactgtgca
gtggccattgggcggcccctgggtgaggtggtgaccctccaagtcctcgagagttccctc
agctgcagtgctggggatgtgttgctgctttgggacaggctcacgtggaagaagatgtgc
gggaagctatctggcatgacttttagctccaagaccaacacgctggtggtgaggcagcgc
cgcgtgcggctggaaggtggggttgtgctgcggtacaggagccggcctgcaccgggagcc
ccccaccgagagtgtgacatgcagctcttcggaccctggggggaaatcgtgagcccctcc
gtgggtgctgatgggaggaactcagggggctgccgcatcttcattaatgtggccccacag
gcccgaattgccatccatgccctggccactgatggcacaggaaccggtgccagctatgtc
ttgatccgggacatccacagcctgaagacgatgacattccgtgggcagcaggcactctac
tgggagtcggagggaagccaggctgagatggagtttagccagggcttcctggaggcgcat
gccagcctgcgaggccagtactggaccctccaatctagagtgcaggaacctggctgggct
gagccctag

  All links  
Gene (73)   
   RefGene (68)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   Ensembl (1)   
   OC (1)   
   VGNC (1)   
Protein sequence (13)   
   UniProt (1)   
   RefSeq(pep) (12)   
DNA sequence (15)   
   RefSeq(nuc) (13)   
   GenBank (1)   
   EMBL (1)   
Protein domain (15)   
   Pfam (15)   
All databases (116)   

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