KEGG   Cricetulus griseus (Chinese hamster): 100763862
Entry
100763862         CDS       T02813                                 
Symbol
Mthfd1
Name
(RefSeq) C-1-tetrahydrofolate synthase, cytoplasmic
  KO
K00288  methylenetetrahydrofolate dehydrogenase (NADP+) / methenyltetrahydrofolate cyclohydrolase / formyltetrahydrofolate synthetase [EC:1.5.1.5 3.5.4.9 6.3.4.3]
Organism
cge  Cricetulus griseus (Chinese hamster)
Pathway
cge00670  One carbon pool by folate
cge01100  Metabolic pathways
cge01240  Biosynthesis of cofactors
Module
cge_M00141  C1-unit interconversion, eukaryotes
Brite
KEGG Orthology (KO) [BR:cge00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00670 One carbon pool by folate
    100763862 (Mthfd1)
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome [BR:cge04147]
    100763862 (Mthfd1)
Enzymes [BR:cge01000]
 1. Oxidoreductases
  1.5  Acting on the CH-NH group of donors
   1.5.1  With NAD+ or NADP+ as acceptor
    1.5.1.5  methylenetetrahydrofolate dehydrogenase (NADP+)
     100763862 (Mthfd1)
 3. Hydrolases
  3.5  Acting on carbon-nitrogen bonds, other than peptide bonds
   3.5.4  In cyclic amidines
    3.5.4.9  methenyltetrahydrofolate cyclohydrolase
     100763862 (Mthfd1)
 6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.4  Other carbon-nitrogen ligases
    6.3.4.3  formate---tetrahydrofolate ligase
     100763862 (Mthfd1)
Exosome [BR:cge04147]
 Exosomal proteins
  Exosomal proteins of other body fluids (saliva and urine)
   100763862 (Mthfd1)
SSDB
Motif
Pfam: FTHFS THF_DHG_CYH_C THF_DHG_CYH
Other DBs
NCBI-GeneID: 100763862
NCBI-ProteinID: XP_027274085
UniProt: G3H4Z5
Position
5:complement(127173702..127241378)
AA seq 936 aa
MAPAEILNGKVVSAQIRDRLKSQVTQMKGQVPGFTPGLAILQVGDRDDSNLYINMKLKAA
EEIGIKATHIKLPRTSTESEVLKYVISLNEDSTVHGFIVQLPLDSENPINTEAVINAITP
DKDVDGLTSISAGKLARGDLNDCFIPCTPKGCLELIKETGVQIAGRHAVVVGRSKIVGAP
MHDLLLWNNATVTTCHSKTADLDKEVNKGDILVVATGQPEMVKGEWIKAGAVVIDCGINY
IPDDTKPNGRKVVGDVAYDQAKERASFITPVPGGVGPMTVAMLMQSTVESAQRFLKKFKP
GKWTIQYNKLSLQTPVPSDIDISRSCKPKPICNLAREIGLLTEEVEPYGDTKAKVLLSTL
KRLKHQPDGKYVVVAGITPTPLGEGKSTTTIGLVQALGAHLNQNVFACVRQPSQGPTFGI
KGGAAGGGYSQVIPMEEFNLHLTGDIHAITAANNLVAAAIDTQIFHELTQTEKALFNRLV
PSKGNGVRKFCDIQIRRLRRLGIEKTDPTTLTDDEIIRFVRLEIDPETITWQRVLDTNDR
FLRKITIGQSPTEKGHTRTAQFDISVASEIMAVLALTTSLKDMIERVGKMVVASSKKGEP
ITVDDLGVSGAVAVLLKDAIKPNLMQTLEGTPVFVHAGPFANIAHGNSSIIADRIALKLV
GPEGFVVTEAGFGADIGMEKFFNIKCRYSGLQPHVVVLVATVRALKMHGGGPTVTAGLPL
PEAYTKENLDLVEKGFSNLRKQIENARMFGVPVVVAMNAFKTDTDAELDLIARLSREHGA
FDAVKCTHWAEGGRGALALAQAVQRASQAPSNFRLLYDLKLSIEDKIRIIAQKIYGADDI
ELLPEAQKKAEVYTKQGFGNLPICMAKTHLSLSHNPEQKGAPTGFILPIRDIRASVGAGF
LYPLVGTMSTMPGLPTRPCFYDIDLDPETEQVIGLF
NT seq 2811 nt   +upstreamnt  +downstreamnt
atggcgccggcggaaatcctgaacgggaaggtggtctccgcgcaaataagggatcgactg
aagagccaggttactcagatgaaggggcaagtccctggcttcacacctggcctggccatc
ctgcaggttggcgacagagatgattccaatctttatataaatatgaagctgaaagctgct
gaagagattgggatcaaagccactcacattaaattaccaagaacctccactgagtctgag
gtgttaaagtatgtcatctccttgaacgaggactccactgtgcatggcttcatagtgcag
ctgcctttggattcagagaatcccattaacactgaagccgtcatcaacgctatcacaccc
gacaaggatgtggatgggttgactagcatcagcgctgggaaacttgccagaggtgatctg
aatgactgcttcattccgtgcacacccaaaggatgcttggaactcatcaaagagacaggg
gtgcagattgccggaaggcacgctgtggtggttgggcgaagtaaaatagttggtgccccc
atgcatgacctgctcctgtggaacaatgccacagtgacaacctgccactccaagactgcc
gatctggacaaggaggtaaataaaggagacattctggtggttgcaacaggacagcctgag
atggtgaaaggggaatggatcaaggccggggctgtcgtcatagactgtggaatcaactac
attccagatgatacaaaaccaaatggaaggaaagttgtgggtgatgtggcgtatgatcaa
gccaaggagagggcgagctttatcacgcctgtccccggaggtgtgggacccatgaccgtg
gcaatgctgatgcagagcacagtagagagcgcacagcgtttcttgaagaaatttaagcca
ggaaagtggacaattcagtacaacaagctgagcctccagacacctgttccaagtgacatt
gatatatcacgatcttgcaaaccaaagcccatctgtaacctggcccgagaaattgggctg
ctcacagaagaggtggaaccatatggggacacaaaggccaaagtcttgctgtccacactg
aaacgcctgaagcaccagcctgatgggaaatacgtggtagtggctggaataactccaaca
cctctgggagaagggaaaagtacaaccacaattgggctggtgcaagcccttggagcccac
ctgaatcagaatgtttttgcgtgtgtccgacagccttctcagggccccacctttggaata
aaaggtggcgctgcaggaggcggctattcccaggtcattcctatggaagagtttaatctc
cacctcactggtgacatccacgccatcactgcagctaataatctcgtggctgctgccatc
gatactcagatatttcatgagctgacccagacagaaaaggctctctttaatcgcttggta
ccttcaaaaggaaatggagtaagaaaattctgtgatatccagatccgaaggttacggagg
ttaggcattgaaaagactgaccccaccacactgacggatgacgagataatcagatttgta
agactggaaattgatccagaaaccataacgtggcagagagtgctggacaccaatgataga
ttcctgaggaagatcactattggacagtctccaacagagaaaggccacacacgcacggct
cagtttgatatctctgtggccagtgaaattatggctgttctggccctcactacttctctg
aaagatatgatagagagagtgggcaaaatggtggtggcatccagtaagaaaggcgaaccc
atcactgttgatgatctgggcgtgagtggagcagtggcggtgctgttgaaggatgcaatc
aaacccaatctcatgcagaccttagagggcacaccggtgtttgtccacgctgggcccttt
gccaacattgcacatgggaattcctccatcattgcagaccggattgcactcaagcttgtt
ggccctgagggcttcgtagtgactgaagcgggattcggagcagacataggaatggaaaag
ttcttcaacatcaagtgccgatattctgggctccagccacacgtggtggttctcgttgcc
actgtcagagctcttaaaatgcatggcggcggccccacggtcactgctggactgcccctt
cccgaggcttacaccaaagagaacctggacctggttgaaaagggcttcagtaacttgagg
aaacaaatagaaaatgctaggatgtttggagtgcccgtggtcgtggccatgaatgcattc
aagacagatacagacgctgagctggacctcatcgcccgcctctccagagaacacggggct
tttgatgctgtcaaatgcacccactgggcagaaggggggcggggagccttagccctggct
caggccgtccagagagcatcacaggcccccagcaacttccggctcctctatgacctcaag
ctctccattgaggataaaatcaggatcatcgcacagaagatctatggggcagatgacatc
gagttgctccccgaagcacagaagaaagcagaagtctacacaaagcagggtttcgggaat
ctacctatctgcatggccaaaacacacctgtctttgtctcacaacccagagcaaaaaggt
gcacctactggcttcattctgcccatccgtgacatccgtgccagcgttggtgctggtttt
ctgtaccctttagttggaacgatgagcacaatgcctggactccctacccggccctgtttt
tatgatattgatttggaccctgaaactgaacaagtgattggattgttttaa

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Ontology (3)   
   KEGG BRITE (3)   
Pathway (4)   
   KEGG PATHWAY (3)   
   KEGG MODULE (1)   
Chemical substance (12)   
   KEGG COMPOUND (12)   
Chemical reaction (6)   
   KEGG ENZYME (3)   
   KEGG REACTION (3)   
Genome (1)   
   KEGG GENOME (1)   
Gene (66)   
   KEGG ORTHOLOGY (1)   
   RefGene (62)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   OC (1)   
Protein sequence (3)   
   UniProt (1)   
   RefSeq(pep) (2)   
DNA sequence (6)   
   RefSeq(nuc) (2)   
   GenBank (2)   
   EMBL (2)   
Protein domain (3)   
   Pfam (3)   
All databases (104)   

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