KEGG   COMPOUND: C00187Help
Entry
C00187                      Compound                               

Name
Cholesterol;
Cholest-5-en-3beta-ol
Formula
C27H46O
Exact mass
386.3549
Mol weight
386.6535
Structure
Mol fileKCF fileDB search
Remark
Same as: D00040
Reaction
Pathway
map00100  Steroid biosynthesis
map00120  Primary bile acid biosynthesis
map00140  Steroid hormone biosynthesis
map00981  Insect hormone biosynthesis
map00984  Steroid degradation
map01066  Biosynthesis of alkaloids derived from terpenoid and polyketide
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
map04913  Ovarian steroidogenesis
map04925  Aldosterone synthesis and secretion
map04927  Cortisol synthesis and secretion
map04934  Cushing syndrome
map04975  Fat digestion and absorption
map04976  Bile secretion
map04977  Vitamin digestion and absorption
map04979  Cholesterol metabolism
map05200  Pathways in cancer
map05217  Basal cell carcinoma
Module
M00101  Cholesterol biosynthesis, squalene 2,3-epoxide => cholesterol
M00104  Bile acid biosynthesis, cholesterol => cholate/chenodeoxycholate
M00107  Steroid hormone biosynthesis, cholesterol => prognenolone => progesterone
Enzyme
1.1.1.145       1.1.3.6         1.3.1.21        1.3.1.72        
1.14.13.-       1.14.14.23      1.14.14.25      1.14.15.6       
1.14.15.15      1.14.19.21      1.14.99.38      2.3.1.26        
2.3.1.73        2.8.2.2         2.8.2.14        3.1.1.13        
3.1.6.2         3.2.1.104       5.3.3.1
Brite
Compounds with biological roles [BR:br08001]
 Steroids
  27-Carbon atoms
   Cholestane derivatives
    C00187  Cholesterol
Lipids [BR:br08002]
 ST  Sterol Lipids
  ST01 Sterols
   ST0101 Cholesterol and derivatives
    C00187  Cholesterol
Phytochemical compounds [BR:br08003]
 Terpenoids
  Steroids
   Cholestane
    C00187  Cholesterol
Carcinogens [BR:br08008]
 Group 3: Not classifiable as to its carcinogenicity to humans
  Compounds
   C00187  Cholesterol
Pharmaceutical additives in Japan [BR:br08316]
 Surfactant
  D00040  [001255] Cholesterol
 Base
  D00040  [001255] Cholesterol
 Diluting agent
  D00040  [001255] Cholesterol
Drugs listed in the Japanese Pharmacopoeia [BR:br08311]
 Chemicals
  D00040  Cholesterol
BRITE hierarchy
Other DBs
CAS: 57-88-5
PubChem: 3487
ChEBI: 16113
ChEMBL: CHEMBL112570 CHEMBL1867358
LIPIDMAPS: LMST01010001 LMST01010081 LMST01010093
LipidBank: SST0005 SST9061
KNApSAcK: C00003648
PDB-CCD: CLR[PDBj]
3DMET: B01181
NIKKAJI: J2.804E
KCF data Show

ATOM        28
            1   C1y C    26.9810  -18.8588
            2   C1y C    25.8103  -19.5344
            3   C1z C    26.9810  -17.5075
            4   C1x C    29.3223  -18.8588
            5   C1y C    24.6454  -18.8588
            6   C1x C    25.8044  -20.8857
            7   C1y C    28.1634  -16.8320
            8   C1x C    25.8103  -16.8320
            9   C1a C    26.9751  -16.1563
            10  C1x C    29.3223  -17.5075
            11  C1z C    23.4631  -19.5344
            12  C1x C    24.6454  -17.5075
            13  C2x C    24.6454  -21.5613
            14  C1c C    28.1634  -15.4807
            15  C2y C    23.4631  -20.8857
            16  C1x C    22.2983  -18.8588
            17  C1a C    23.4514  -18.1832
            18  C1b C    29.3573  -14.7934
            19  C1a C    26.9634  -14.7877
            20  C1x C    22.2983  -21.5613
            21  C1x C    21.1276  -19.5344
            22  C1b C    30.5513  -15.4864
            23  C1y C    21.1276  -20.8857
            24  C1b C    31.7453  -14.7934
            25  O1a O    19.9453  -21.5613
            26  C1c C    32.9451  -15.4864
            27  C1a C    34.1391  -14.7992
            28  C1a C    32.9393  -17.0763
BOND        31
            1     1   2 1
            2     1   3 1
            3     1   4 1
            4     2   5 1
            5     2   6 1
            6     3   7 1
            7     3   8 1
            8     3   9 1 #Up
            9     4  10 1
            10    5  11 1
            11    5  12 1
            12    6  13 1
            13    7  14 1
            14   11  15 1
            15   11  16 1
            16   11  17 1 #Up
            17   14  18 1
            18   14  19 1 #Down
            19   15  20 1
            20   16  21 1
            21   18  22 1
            22   20  23 1
            23   22  24 1
            24   23  25 1 #Up
            25   24  26 1
            26   26  27 1
            27   26  28 1
            28    7  10 1
            29    8  12 1
            30   13  15 2
            31   21  23 1

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