KEGG   Drosophila melanogaster (fruit fly): Dmel_CG11680
Entry
Dmel_CG11680      CDS       T00030                                 
Symbol
mle
Name
(RefSeq) maleless, isoform A
  KO
K13184  ATP-dependent RNA helicase A [EC:5.6.2.6]
Organism
dme  Drosophila melanogaster (fruit fly)
Brite
KEGG Orthology (KO) [BR:dme00001]
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03041 Spliceosome [BR:dme03041]
    Dmel_CG11680 (mle)
Enzymes [BR:dme01000]
 5. Isomerases
  5.6  Isomerases altering macromolecular conformation
   5.6.2  Enzymes altering nucleic acid conformation
    5.6.2.6  RNA 3'-5' helicase
     Dmel_CG11680 (mle)
Spliceosome [BR:dme03041]
 Other splicing related proteins
  Spliceosome associated proteins (SAPs)
   RNA helicase-like proteins
    Dmel_CG11680 (mle)
SSDB
Motif
Pfam: dsrm OB_NTP_bind Helicase_C DEAD HA2_C HA2_N Dicer_dimer nSTAND3 AAA_19 AAA_14 AAA_22 ATPase_2
Other DBs
NCBI-GeneID: 35523
NCBI-ProteinID: NP_476641
FlyBase: FBgn0002774
UniProt: P24785
Structure
Position
2R
AA seq 1293 aa
MDIKSFLYQFCAKSQIEPKFDIRQTGPKNRQRFLCEVRVEPNTYIGVGNSTNKKDAEKNA
CRDFVNYLVRVGKLNTNDVPADAGASGGGPRTGLEGAGMAGGSGQQKRVFDGQSGPQDLG
EAYRPLNHDGGDGGNRYSVIDRIQEQRDMNEAEAFDVNAAIHGNWTIENAKERLNIYKQT
NNIRDDYKYTPVGPEHARSFLAELSIYVPALNRTVTARESGSNKKSASKSCALSLVRQLF
HLNVIEPFSGTLKKKKDEQLKPYPVKLSPNLINKIDEVIKGLDLPVVNPRNIKIELDGPP
IPLIVNLSRIDSSQQDGEKRQESSVIPWAPPQANWNTWHACNIDEGELATTSIDDLSMDY
ERSLRDRRQNDNEYRQFLEFREKLPIAAMRSEILTAINDNPVVIIRGNTGCGKTTQIAQY
ILDDYICSGQGGYANIYVTQPRRISAISVAERVARERCEQLGDTVGYSVRFESVFPRPYG
AILFCTVGVLLRKLEAGLRGVSHIIVDEIHERDVNSDFLLVILRDMVDTYPDLHVILMSA
TIDTTKFSKYFGICPVLEVPGRAFPVQQFFLEDIIQMTDFVPSAESRRKRKEVEDEEQLL
SEDKDEAEINYNKVCEDKYSQKTRNAMAMLSESDVSFELLEALLMHIKSKNIPGAILVFL
PGWNLIFALMKFLQNTNIFGDTSQYQILPCHSQIPRDEQRKVFEPVPEGVTKIILSTNIA
ETSITIDDIVFVIDICKARMKLFTSHNNLTSYATVWASKTNLEQRKGRAGRVRPGFCFTL
CSRARFQALEDNLTPEMFRTPLHEMALTIKLLRLGSIHHFLSKALEPPPVDAVIEAEVLL
REMRCLDANDELTPLGRLLARLPIEPRLGKMMVLGAVFGCADLMAIMASYSSTFSEVFSL
DIGQRRLANHQKALSGTKCSDHVAMIVASQMWRREKQRGEHMEARFCDWKGLQMSTMNVI
WDAKQQLLDLLQQAGFPEECMISHEVDERIDGDDPVLDVSLALLCLGLYPNICVHKEKRK
VLTTESKAALLHKTSVNCSNLAVTFPYPFFVFGEKIRTRAVSCKQLSMVSPLQVILFGSR
KIDLAANNIVRVDNWLNFDIEPELAAKIGALKPALEDLITVACDNPSDILRLEEPYAQLV
KVVKDLCVKSAGDFGLQRESGILPHQSRQFSDGGGPPKRGRFETGRFTNSSFGRRGNGRT
FGGGYGNNGGGYGNNGGGYGNIGGGYGNNAGGYGNNGGYGNNGGGYRNNGGGYGNNGGGY
GNKRGGFGDSFESNRGSGGGFRNGDQGGRWGNF
NT seq 3882 nt   +upstreamnt  +downstreamnt
atggatataaaatcttttttgtaccaattttgtgctaagtcgcaaatagaaccaaagttt
gatattcgccaaacgggtcccaaaaatcgccagcggttcctttgcgaggttcgtgtagag
ccaaatacctatattggtgtgggtaattccactaacaaaaaggatgccgagaaaaatgcg
tgccgtgattttgtcaactacctagtgcgcgtgggcaaactgaacaccaatgatgttcca
gcggatgctggtgcttcggggggcggacctaggactggtctggagggtgcgggcatggca
gggggcagtggacagcagaagcgagtgtttgatggtcagtcgggtccacaggatctgggt
gaggcctatcgccctctaaaccacgatggcggtgacggcggtaaccgctactcagtaatt
gatcgcatccaggagcagagggacatgaacgaagcggaggctttcgatgtcaacgctgcc
atccacggtaactggaccatagagaatgccaaagagcgactgaacatttacaagcagacg
aacaacattcgcgacgattacaaatatacaccagtgggcccggaacacgctaggagcttt
ttggccgaattgtccatttatgtgccggcgctcaatcgcacggtgacggcccgtgagtcg
ggttcaaacaagaagtctgccagcaagtcatgcgccctgtccctggtgcgccaacttttc
catttaaatgtgatagagccctttagtggaactctgaagaaaaaaaaggatgagcagctg
aagccatatccggtgaagctttcgccaaatctgataaacaaaattgatgaggtgattaag
ggtttggaccttcctgtcgtaaacccgcgcaatatcaaaatcgaactggacggtcctccg
attcctctcattgtgaacttaagccgtatagattcctcgcaacaggatggcgaaaaacgt
caggaaagctccgtgattccgtgggctcctcctcaggcaaactggaatacgtggcatgcc
tgcaacatcgacgaaggcgaactggcaaccacctctattgatgacctttcgatggactac
gaacgctcgctgcgtgatcgccgccaaaacgacaacgagtaccgacaattcctcgagttc
cgcgaaaagctgcccattgcagcgatgcggtcggaaattttaaccgcaattaatgacaat
ccagtggtaatcattcgtggaaacacagggtgcggaaagactacccagattgcccaatac
attcttgatgactacatctgctccggccagggcgggtacgctaatatttatgtgacccag
cctcgtcgcatttcagccatttctgtggccgagcgcgtagctcgcgagcggtgcgagcaa
ttgggcgacactgtaggctactcggtgcgatttgagtctgtgtttccacgaccctacggc
gcaatcctcttttgcaccgtgggtgtgttgctgcgcaagctggaggctggcttacgagga
gtgtcgcatattattgtggacgaaatccacgagagagacgtgaacagcgactttttgctg
gtcatccttcgcgacatggtcgacacatatccggacctgcatgttattcttatgtcggcc
actattgatacaacgaaattttccaaatattttggcatctgtcccgtattggaagtaccc
ggaagagcatttcccgtgcagcaatttttcttggaggacattattcagatgacagacttt
gtgccttcggcggagtcgcgccgaaagcgcaaggaagtggaggacgaggagcaattgctt
tccgaggacaaggacgaggcggaaatcaactataacaaggtgtgcgaggacaagtattca
caaaagactcgaaatgctatggccatgctatccgaatcggacgttagctttgagctgctg
gaggcattattgatgcatattaagtcaaaaaatattcccggtgctatcttagtattcctg
cccggttggaacctgatctttgcgcttatgaagtttctgcaaaatacaaacatttttggt
gatacatcccaataccaaattttgccgtgccactcgcagattccacgagacgagcaacgc
aaggttttcgagcctgttccagaaggcgtaaccaagattatactttctaccaacattgca
gagacttctataactattgacgacattgttttcgtaattgatatatgtaaggcgcgcatg
aagctctttacttcacataacaacctaaccagctacgccaccgtttgggcaagcaaaacc
aatttggagcagcgcaagggccgagctggacgtgtccgaccaggcttctgcttcacactc
tgttcgcgtgcccgcttccaagcgctagaggacaatcttacgccggagatgttccgcaca
ccgttgcacgagatggcgttgaccattaaattactcagactgggctccattcaccacttt
ttgtcaaaggcattggagccacctccggtagacgcagtaatcgaagctgaggtgttgctt
cgcgagatgcgctgccttgacgctaacgatgaacttactccattggggcgcctgctggca
cgcctcccaattgaaccaagacttggaaagatgatggtcctcggcgcagtatttggctgc
gccgatctaatggccattatggcttcgtactctagcaccttctcagaggtgtttagtctt
gatataggtcaacgtcgcctggcaaatcatcagaaagcgttgagtggtaccaaatgttcc
gaccacgtggcaatgattgtagcttcacaaatgtggcggcgcgagaaacaacgcggtgag
catatggaagctcggttctgtgactggaaaggactgcaaatgagtactatgaacgttatc
tgggatgccaagcagcagttactggatctccttcagcaggcaggattcccagaagagtgt
atgatatcgcacgaggtagacgaaaggattgatggggatgaccccgtgctggatgtgtcc
ctggcgctgctgtgcttgggtctctaccccaacatttgcgtgcacaaggagaagcgcaaa
gtgctgactacagagtctaaagcagcgttactgcacaaaacctcggtgaattgcagcaac
ttggccgtcacatttccgtatccgttcttcgttttcggcgagaagattcgcacgcgagct
gtttcctgcaagcaactatctatggtctcgcccttgcaggtgatattgtttggatcgcgc
aagattgacttggccgccaacaatatagtgcgcgttgacaactggcttaacttcgacata
gagccggaacttgcggccaagattggtgcccttaagccggccctggaggatcttatcacg
gtggcgtgcgacaacccttccgacatacttcgccttgaggagccctatgcacagctggtc
aaagtggtcaaagacctttgcgttaagagcgccggagacttcggactgcagcgtgaatca
ggaattctgccgcaccaatcacgtcagttcagtgacggcggaggaccgcccaaacgaggt
cgctttgagacaggacgctttactaacagcagctttggtcgccgtggaaacggcagaact
tttggaggaggatatggaaataatggaggaggatatggaaataatggaggaggatatgga
aatattggaggaggatatggaaataatgcaggaggttatggaaataatggtggatatgga
aataatggcggaggttatagaaataatggtggaggatatggaaacaatggcggaggatat
gggaacaagagaggtggatttggagactcatttgaaagcaatagaggatcaggcggcggc
tttagaaatggcgaccaaggcggccgctggggtaacttttaa

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Ontology (3)   
   KEGG BRITE (3)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (46)   
   KEGG ORTHOLOGY (1)   
   RefGene (41)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
   FLYBASE (1)   
   OC (1)   
Protein sequence (4)   
   UniProt (1)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (2)   
   RefSeq(nuc) (2)   
3D Structure (10)   
   PDB (10)   
Protein domain (12)   
   Pfam (12)   
All databases (79)   

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