| Entry |
|
|---|
| Name |
Phenobarbital sodium (JAN/USP/INN);
Luminal sodium (TN) |
|---|
| Formula |
C12H11N2O3. Na
|
|---|
| Exact mass |
254.0667
|
|---|
| Mol weight |
254.2171
|
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| Structure |
|
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| Simcomp |
|
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| Class |
|
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| Remark |
| Product (DG00845): | D00506<JP> D00701<JP> |
|
|---|
| Efficacy |
Antianxiety, Anticonvulsant, Sedative-hypnotic |
|---|
| Disease |
|
|---|
| Comment |
Barbiturates
|
|---|
| Target |
|
|---|
| Pathway |
| hsa04080 | Neuroactive ligand-receptor interaction |
|
|---|
| Interaction |
|
|---|
| Structure map |
| map07230 | GABA-A receptor agonists/antagonists |
|
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| Brite |
Anatomical Therapeutic Chemical (ATC) classification [BR:br08303]
N NERVOUS SYSTEM
N03 ANTIEPILEPTICS
N03A ANTIEPILEPTICS
N03AA Barbiturates and derivatives
N03AA02 Phenobarbital
D00701 Phenobarbital sodium (JAN/USP/INN) <JP>
USP drug classification [BR:br08302]
Anticonvulsants
Gamma-aminobutyric Acid (GABA) Augmenting Agents
Barbituates
Phenobarbital
D00701 Phenobarbital sodium (JAN/USP/INN)
Therapeutic category of drugs in Japan [BR:br08301]
1 Agents affecting nervous system and sensory organs
11 Agents affecting central nervous system
112 Hypnotics and sedatives, anxiolytics
1125 Barbiturates and thiobarbiturates
D00701 Phenobarbital sodium (JAN/USP/INN)
113 Antiepileptics
1139 Others
D00701 Phenobarbital sodium (JAN/USP/INN)
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00845 Phenobarbital
D00701 Phenobarbital sodium
DG03199 Antiepileptic agent
DG01904 Barbiturate antiepileptic
DG00845 Phenobarbital
D00701 Phenobarbital sodium
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
DG00845 Phenobarbital
D00701 Phenobarbital sodium
DG02891 CYP2B6 inducer
DG00845 Phenobarbital
D00701 Phenobarbital sodium
DG02886 CYP2C9 inducer
DG00845 Phenobarbital
D00701 Phenobarbital sodium
DG02853 CYP3A/CYP3A4 inducer
DG00845 Phenobarbital
D00701 Phenobarbital sodium
Target-based classification of drugs [BR:br08310]
Ion channels
Ligand-gated ion channels
GABA (ionotropic)
GABR
D00701 Phenobarbital sodium (JAN/USP/INN) <JP>
Drug metabolizing enzymes and transporters [br08309.html]
Drug metabolizing enzymes
D00701
Drug groups [BR:br08330]
Neuropsychiatric agent
DG01567 GABA-A receptor agonist
DG00845 Phenobarbital
DG03199 Antiepileptic agent
DG01904 Barbiturate antiepileptic
DG00845 Phenobarbital
Metabolizing enzyme inducer
DG01637 CYP1A2 inducer
DG00845 Phenobarbital
DG02891 CYP2B6 inducer
DG00845 Phenobarbital
DG02886 CYP2C9 inducer
DG00845 Phenobarbital
DG02853 CYP3A/CYP3A4 inducer
DG00845 Phenobarbital
|
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| Other DBs |
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| KCF data |
ATOM 18
1 C1z C 25.6023 -19.5651
2 C8y C 26.8072 -18.8573
3 C5x C 25.6023 -20.9690
4 C5x C 24.3621 -18.8807
5 C1b C 26.8014 -20.2611
6 C8x C 28.0180 -19.5417
7 C8x C 26.7897 -17.4536
8 N1x N 24.3621 -21.6709
9 O5x O 26.7955 -21.6709
10 N2x N 23.1573 -19.5651
11 O5x O 24.3621 -17.4653
12 C1a C 28.2053 -20.2611
13 C8x C 29.2230 -18.8340
14 C8x C 27.9946 -16.7457
15 C2y C 23.1573 -20.9690
16 C8x C 29.2113 -17.4359
17 O1a O 21.9465 -21.6650 #-
18 Z Na 20.0103 -19.7054 #+
BOND 18
1 1 2 1
2 1 3 1
3 1 4 1
4 1 5 1
5 2 6 2
6 2 7 1
7 3 8 1
8 3 9 2
9 4 10 1
10 4 11 2
11 5 12 1
12 6 13 1
13 7 14 2
14 8 15 1
15 13 16 2
16 15 17 1
17 10 15 2
18 14 16 1
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