KEGG   DRUG: Glycol salicylateHelp
Entry
D01557                      Drug                                   

Name
Glycol salicylate (JAN);
Ethylene glycol salicylate;
Norgesic (TN);
Phlogont (TN)
Formula
C9H10O4
Exact mass
182.0579
Mol weight
182.1733
Structure
Mol fileKCF fileDB search
Simcomp SIMCOMP
Class
Anti-inflammatory
 DG01909  Anti-inflammatory drug, salicylic acid derivatives
 DG01504  Nonsteroidal anti-inflammatory drug (NSAID)
  DG01909  Anti-inflammatory drug, salicylic acid derivatives
Remark
Product (mixture): D08717<JP> D08728<JP> D08731<JP>
Efficacy
Analgesic, Anti-inflammatory, COX inhibitor
Comment
Salicylic acid derivative
Target
PTGS1 (COX1) [HSA:5742] [KO:K00509]
PTGS2 (COX2) [HSA:5743] [KO:K11987]
  Pathway
hsa00590  Arachidonic acid metabolism
Interaction
Drug interaction
Brite
Classification of Japanese OTC drugs [BR:br08313]
 Agents for integumentary system
  57 Analgesic, antipruritic, astringent, and anti-inflammatory remedies (incl. gel patches)
   D01557  Glycol salicylate (JAN)
Risk category of Japanese OTC drugs [BR:br08312]
 Third-class OTC drugs
  Inorganic and organic chemicals
   Glycol salicylate
    D01557  Glycol salicylate (JAN)
Pharmaceutical additives in Japan [BR:br08316]
 Base
  D01557  [102270] Ethyleneglycol salicylate
 Solvent
  D01557  [102270] Ethyleneglycol salicylate
Target-based classification of drugs [BR:br08310]
 Enzymes
  Oxidoreductases (EC1)
   Prostaglandin synthase
    PTGS1 (COX1)
     D01557  Glycol salicylate (JAN)
    PTGS2 (COX2)
     D01557  Glycol salicylate (JAN)
BRITE hierarchy
Other DBs
CAS: 87-28-5
PubChem: 7848620
ChEMBL: CHEMBL173562
LigandBox: D01557
NIKKAJI: J55.649A
KCF data Show

ATOM        13
            1   C8y C    29.5221  -15.2210
            2   C8y C    30.7455  -15.9193
            3   C8x C    28.3177  -15.9193
            4   C7a C    29.5156  -13.8310
            5   C8x C    30.7455  -17.3285
            6   O1a O    31.9499  -15.2210
            7   C8x C    28.3177  -17.3285
            8   O7a O    30.7262  -13.1327
            9   O6a O    28.3049  -13.1391
            10  C8x C    29.5221  -18.0396
            11  C1b C    31.9363  -13.8322
            12  C1b C    33.1469  -13.1339
            13  O1a O    34.3570  -13.8331
BOND        13
            1     1   4 1
            2     2   5 2
            3     2   6 1
            4     3   7 1
            5     4   8 1
            6     4   9 2
            7     5  10 1
            8     7  10 2
            9     8  11 1
            10    1   2 1
            11   11  12 1
            12    1   3 2
            13   12  13 1

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