KEGG   DRUG: DocarpamineHelp
Entry
D01903                      Drug                                   

Name
Docarpamine (JAN/INN);
Tanadopa (TN)
Formula
C21H30N2O8S
Exact mass
470.1723
Mol weight
470.5365
Structure
Mol fileKCF fileDB search
Class
Cardiovascular agent
 DG01703  Cardiotonic
  DG01699  Catecholamine cardiotonic
Remark
Therapeutic category: 2119
Product: D01903<JP>
Efficacy
Cardiotonic, Dopamine D1 receptor agonist, beta1-Adrenergic receptor agonist
Comment
Active form of prodrug: Dopamine [DR:D07870]
Target
DRD1 [HSA:1812] [KO:K04144]
ADRB1 [HSA:153] [KO:K04141]
  Pathway
hsa04024  cAMP signaling pathway
hsa04080  Neuroactive ligand-receptor interaction
hsa04261  Adrenergic signaling in cardiomyocytes
hsa04728  Dopaminergic synapse
Interaction
Drug interaction
Brite
Therapeutic category of drugs in Japan [BR:br08301]
 2  Agents affecting individual organs
  21  Cardiovascular agents
   211  Cardiotonics
    2119  Others
     D01903  Docarpamine (JAN/INN)
Target-based classification of drugs [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Adrenaline
    ADRB1
     D01903  Docarpamine (JAN/INN) <JP>
   Dopamine
    DRD1
     D01903  Docarpamine (JAN/INN) <JP>
Prodrugs [br08324.html]
 D01903
BRITE hierarchy
Other DBs
CAS: 74639-40-0
PubChem: 7848965
ChEBI: 31513
ChEMBL: CHEMBL2106351
LigandBox: D01903
NIKKAJI: J23.876G
KCF data Show

ATOM        32
            1   C8y C    14.9800  -16.5200
            2   C8y C    14.9800  -15.1200
            3   C8x C    16.2400  -14.4200
            4   C8y C    17.4300  -15.1200
            5   C8x C    17.4300  -16.5200
            6   C8x C    16.2400  -17.2200
            7   C1b C    18.6200  -14.4200
            8   C1b C    19.8800  -15.1200
            9   N1b N    21.0700  -14.4200
            10  C5a C    22.2600  -15.1200
            11  C1c C    23.5200  -14.4200
            12  C1b C    24.7100  -15.1200
            13  C1b C    25.9000  -14.4200
            14  S2a S    27.1600  -15.1200
            15  C1a C    28.3500  -14.4900
            16  O7a O    13.7900  -14.4200
            17  C7a C    12.6000  -15.1200
            18  O7a O    11.4100  -14.4200
            19  C1b C    10.1500  -15.1200
            20  C1a C     8.9600  -14.4200
            21  O7a O    13.7900  -17.2200
            22  C7a C    13.7900  -18.6200
            23  O7a O    12.6000  -19.3200
            24  C1b C    12.6000  -20.7200
            25  C1a C    11.4100  -21.4200
            26  O6a O    12.6000  -16.5200
            27  O6a O    14.9800  -19.3200
            28  O5a O    22.2600  -16.5200
            29  N1b N    23.5200  -13.0200
            30  C5a C    24.7100  -12.3200
            31  O5a O    24.7100  -10.9200
            32  C1a C    25.9000  -13.0200
BOND        32
            1     2  16 1
            2     7   8 1
            3    16  17 1
            4     2   3 1
            5    17  18 1
            6     8   9 1
            7    18  19 1
            8     3   4 2
            9    19  20 1
            10    9  10 1
            11    1  21 1
            12    4   5 1
            13   21  22 1
            14   10  11 1
            15   22  23 1
            16    5   6 2
            17   23  24 1
            18   11  12 1
            19   24  25 1
            20    6   1 1
            21   17  26 2
            22   12  13 1
            23   22  27 2
            24   10  28 2
            25   13  14 1
            26   11  29 1 #Up
            27    4   7 1
            28   29  30 1
            29   14  15 1
            30   30  31 2
            31    1   2 2
            32   30  32 1

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