KEGG   DRUG: リスペリドンHelp
エントリ  
D00426                      Drug                                   

一般名   
リスペリドン (JP17);
Risperidone (JP17/USAN/INN)
商品名   
  後発品
リスペリドン (ニプロ), リスペリドン (ファイザー), リスペリドン (ファイザー), リスペリドン (全星薬品工業), リスペリドン (全星薬品工業), リスペリドン (共和薬品工業), リスペリドン (共和薬品工業), リスペリドン (共和薬品工業), リスペリドン (同仁医薬化工), リスペリドン (大原薬品工業), リスペリドン (小林化工), リスペリドン (小林化工), リスペリドン (小林化工), リスペリドン (小林化工), リスペリドン (日医工), リスペリドン (日医工), リスペリドン (東和薬品), リスペリドン (東和薬品), リスペリドン (東和薬品), リスペリドン (武田テバファーマ), リスペリドン (沢井製薬), リスペリドン (沢井製薬), リスペリドン (皇漢堂製薬), リスペリドン (長生堂製薬), リスペリドン (高田製薬), リスペリドン (高田製薬), リスペリドン (高田製薬)
Similar product
米国の商品 
  後発品
RISPERIDONE (A-S Medication Solutions), RISPERIDONE (A-S Medication Solutions), RISPERIDONE (A-S Medication Solutions), RISPERIDONE (ATLANTIC BIOLOGICALS CORP.), RISPERIDONE (Aidarex Pharmaceuticals LLC), RISPERIDONE (Ajanta Pharma Limited), RISPERIDONE (American Health Packaging), RISPERIDONE (Amneal Pharmaceuticals LLC), RISPERIDONE (Aphena Pharma Solutions - Tennessee), RISPERIDONE (Aphena Pharma Solutions - Tennessee), RISPERIDONE (Atlantic Biologicals Corps), RISPERIDONE (Atlantic Biologicals Corps), RISPERIDONE (Aurobindo Pharma Limited), RISPERIDONE (Aurolife Pharma LLC), RISPERIDONE (AvPAK), RISPERIDONE (Breckenridge Pharmaceutical), RISPERIDONE (Bryant Ranch Prepack), RISPERIDONE (Bryant Ranch Prepack), RISPERIDONE (Bryant Ranch Prepack), RISPERIDONE (Bryant Ranch Prepack), RISPERIDONE (Bryant Ranch Prepack), RISPERIDONE (Bryant Ranch Prepack), RISPERIDONE (Cadila Healthcare Limited), RISPERIDONE (Cadila Healthcare Limited), RISPERIDONE (Cardinal Health), RISPERIDONE (Carilion Materials Management), RISPERIDONE (Citron Pharma LLC), RISPERIDONE (Clinical Solutions Wholesale), RISPERIDONE (Contract Pharmacy Services-PA), RISPERIDONE (Contract Pharmacy Services-PA), RISPERIDONE (DIRECT RX), RISPERIDONE (DOH CENTRAL PHARMACY), RISPERIDONE (Dr. Reddy's Laboratories Limited), RISPERIDONE (Dr. Reddy's Laboratories Limited), RISPERIDONE (Dr. Reddy's Laboratories Limited), RISPERIDONE (H.J. Harkins Company), RISPERIDONE (Heritage Pharmaceuticals), RISPERIDONE (Hikma Pharmaceutical), RISPERIDONE (Jubilant Cadista Pharmaceuticals), RISPERIDONE (Lake Erie Medical DBA Quality Care Products LLC), RISPERIDONE (Lake Erie Medical DBA Quality Care Products LLC), RISPERIDONE (Lake Erie Medical DBA Quality Care Products LLC), RISPERIDONE (Lannett Company), RISPERIDONE (MSM Repackaging), RISPERIDONE (Major Pharmaceuticals), RISPERIDONE (Mylan Institutional), RISPERIDONE (Mylan Institutional), RISPERIDONE (Mylan Pharmaceuticals), RISPERIDONE (NCS HealthCare of KY), RISPERIDONE (NCS HealthCare of KY), RISPERIDONE (NuCare Pharmaceuticals), RISPERIDONE (NuCare Pharmaceuticals), RISPERIDONE (NuCare Pharmaceuticals), RISPERIDONE (Nucare Pharmaceuticals), RISPERIDONE (PD-Rx Pharmaceuticals), RISPERIDONE (PD-Rx Pharmaceuticals), RISPERIDONE (Par Pharmaceutical), RISPERIDONE (Par Pharmaceutical), RISPERIDONE (Preferred Pharmaceuticals), RISPERIDONE (Proficient Rx LP), RISPERIDONE (Proficient Rx LP), RISPERIDONE (Proficient Rx LP), RISPERIDONE (Proficient Rx LP), RISPERIDONE (Proficient Rx LP), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (REMEDYREPACK), RISPERIDONE (Ratiopharm), RISPERIDONE (Rebel Distributors Corp), RISPERIDONE (Sandoz), RISPERIDONE (Solco Healthcare US), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (State of Florida DOH Central Pharmacy), RISPERIDONE (Sun Pharmaceutical Industries), RISPERIDONE (TYA Pharmaceuticals), RISPERIDONE (TYA Pharmaceuticals), RISPERIDONE (Taro Pharmaceuticals U.S.A.), RISPERIDONE (Torrent Pharmaceuticals Limited), RISPERIDONE (Torrent Pharmaceuticals Limited), RISPERIDONE (Unit Dose Services), RISPERIDONE (WOCKHARDT LIMITED), RISPERIDONE (WOCKHARDT LIMITED), RISPERIDONE (WOCKHARDT USA LLC.), RISPERIDONE (West-Ward Pharmaceuticals Corp), RISPERIDONE (Wockhardt USA LLC.), RISPERIDONE (Zydus Pharmaceuticals (USA)), RISPERIDONE (Zydus Pharmaceuticals (USA))
組成式   
C23H27FN4O2
質量    
410.2118
分子量   
410.4845
構造式   
Mol fileKCF fileDB search
Simcomp    SIMCOMP
クラス   
循環器系用薬
 DG01466  アドレナリン受容体拮抗薬
  DG01465  α-アドレナリン受容体拮抗薬
   DG01457  α1-アドレナリン受容体拮抗薬
精神神経系用薬
 DG01478  ドパミン拮抗薬
  DG01474  ドパミンD2-受容体拮抗薬
代謝酵素基質薬
 DG01644  CYP2D6基質薬
 DG02913  CYP3A4基質薬
コード   
薬効分類: 1179
ATCコード: N05AX08
商品: D00426<JP/US>
効能    
統合失調症治療薬, 神経遮断薬
  疾患
統合失調症 [DS:H01649]
コメント  
セロトニン・ドパミンアンタゴニスト (SDA)
プロドラッグ活性体: パリペリドン [DR:D05339]
ターゲット 
DRD2 [HSA:1813] [KO:K04145]
HTR2A [HSA:3356] [KO:K04157]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04726  セロトニン作動性シナプス
hsa04728  ドーパミン作動性シナプス
代謝    
Enzyme: CYP2D6 [HSA:1565], CYP3A4 [HSA:1576]
相互作用  
Drug interaction
構造マップ 
map07028  抗精神病薬
map07211  セロトニン受容体の作動薬と拮抗薬
map07213  ドパミン受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   117  精神神経用剤
    1179  その他の精神神経用剤
     D00426  リスペリドン (JP17)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05A 統合失調症薬
    N05AX その他の抗精神病薬
     N05AX08 リスペリドン
      D00426  リスペリドン (JP17) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗精神病薬
  第2世代/非定型
   リスペリドン
    D00426  リスペリドン (JP17)
 双極性障害治療薬
  その他双極性障害治療薬
   リスペリドン
    D00426  リスペリドン (JP17)
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00426  リスペリドン
  D00426  リスペリドン錠
  D00426  リスペリドン細粒
  D00426  リスペリドン内服液
Target-based classification of drugs  [BR:br08310]
 G Protein-coupled receptors
  Rhodopsin family
   Dopamine
    DRD2
     D00426  Risperidone (JP17/USAN/INN) <JP/US>
   Serotonin
    HTR2A
     D00426  Risperidone (JP17/USAN/INN) <JP/US>
治療薬の医薬品クラス [jp08360.html]
 精神性疾患薬
  D00426
BRITE hierarchy
リンク   
CAS: 106266-06-2
PubChem: 7847492
ChEBI: 8871
ChEMBL: CHEMBL85
DrugBank: DB00734
PDB-CCD: 8NU[PDBj]
LigandBox: D00426
日化辞: J138.382E

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