KEGG   DRUG: クエチアピンフマル酸塩
エントリ  
D00458                      Drug                                   
一般名   
クエチアピンフマル酸塩 (JP18);
Quetiapine fumarate (JP18/USP)
商品名   
クエチアピン (沢井製薬), セロクエル (アステラス製薬), ビプレッソ (共和薬品工業)
  後発品
クエチアピン (Meiji Seikaファルマ), クエチアピン (サンド), クエチアピン (シオノケミカル), クエチアピン (ニプロESファーマ), クエチアピン (ニプロESファーマ), クエチアピン (ニプロESファーマ), クエチアピン (ヴィアトリス・ヘルスケア), クエチアピン (共創未来ファーマ), クエチアピン (共和薬品工業), クエチアピン (日医工), クエチアピン (日医工岐阜工場), クエチアピン (日新製薬－山形), クエチアピン (日新製薬－山形), クエチアピン (日本ジェネリック), クエチアピン (東和薬品), クエチアピン (第一三共エスファ), クエチアピン (高田製薬)
米国の商品 
SEROQUEL (AstraZeneca Pharmaceuticals LP), SEROQUEL (AstraZeneca Pharmaceuticals LP)
  後発品
QUETIAPINE (A-S Medication Solutions), QUETIAPINE (A-S Medication Solutions), QUETIAPINE (A-S Medication Solutions), QUETIAPINE (ACI Healthcare USA), QUETIAPINE (Accord Healthcare), QUETIAPINE (Advanced Rx Pharmacy of Tennessee), QUETIAPINE (Advanced Rx Pharmacy of Tennessee), QUETIAPINE (Amneal Pharmaceuticals LLC), QUETIAPINE (Aphena Pharma Solutions - Tennessee), QUETIAPINE (AvKARE), QUETIAPINE (BluePoint Laboratories), QUETIAPINE (Bryant Ranch Prepack), QUETIAPINE (Bryant Ranch Prepack), QUETIAPINE (Bryant Ranch Prepack), QUETIAPINE (Bryant Ranch Prepack), QUETIAPINE (Bryant Ranch Prepack), QUETIAPINE (Bryant Ranch Prepack), QUETIAPINE (Golden State Medical Supply), QUETIAPINE (Macleods Pharmaceuticals Limited), QUETIAPINE (NCS HealthCare of KY), QUETIAPINE (NCS HealthCare of KY), QUETIAPINE (Northstar RxLLC), QUETIAPINE (PD-Rx Pharmaceuticals), QUETIAPINE (Preferred Pharmaceuticals), QUETIAPINE (Proficient Rx LP), QUETIAPINE (Proficient Rx LP), QUETIAPINE (Proficient Rx LP), QUETIAPINE (REMEDYREPACK), QUETIAPINE (REMEDYREPACK), QUETIAPINE (REMEDYREPACK), QUETIAPINE (REMEDYREPACK), QUETIAPINE (RPK Pharmaceuticals), QUETIAPINE (RPK Pharmaceuticals), QUETIAPINE (RPK Pharmaceuticals), QUETIAPINE (ScieGen Pharmaceuticals), QUETIAPINE (Solco Healthcare U.S.), QUETIAPINE (Solco Healthcare US), QUETIAPINE (Teva Pharmaceuticals USA), QUETIAPINE (Unichem Pharmaceuticals (USA)), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (A-S Medication Solutions), QUETIAPINE FUMARATE (Accord Healthcare), QUETIAPINE FUMARATE (Accord Healthcare), QUETIAPINE FUMARATE (Advanced Rx Pharmacy of Tennessee), QUETIAPINE FUMARATE (Advanced Rx Pharmacy of Tennessee), QUETIAPINE FUMARATE (Alembic Pharmaceuticals Limited), QUETIAPINE FUMARATE (American Health Packaging), QUETIAPINE FUMARATE (Aphena Pharma Solutions - Tennessee), QUETIAPINE FUMARATE (Aphena Pharma Solutions - Tennessee), QUETIAPINE FUMARATE (Aphena Pharma Solutions - Tennessee), QUETIAPINE FUMARATE (Ascend Laboratories), QUETIAPINE FUMARATE (Aurobindo Pharma Limited), QUETIAPINE FUMARATE (Aurobindo Pharma Limited), QUETIAPINE FUMARATE (AvPAK), QUETIAPINE FUMARATE (BluePoint Laboratories), QUETIAPINE FUMARATE (Bluepoint Laboratories), QUETIAPINE FUMARATE (Bluepoint Laboratories), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Bryant Ranch Prepack), QUETIAPINE FUMARATE (Camber Pharmaceuticals), QUETIAPINE FUMARATE (Cardinal Health 107), QUETIAPINE FUMARATE (Direct Rx), QUETIAPINE FUMARATE (Direct_Rx), QUETIAPINE FUMARATE (Direct_Rx), QUETIAPINE FUMARATE (Direct_Rx), QUETIAPINE FUMARATE (Direct_Rx), QUETIAPINE FUMARATE (Direct_Rx), QUETIAPINE FUMARATE (Dr.Reddy's Laboratories Limited), QUETIAPINE FUMARATE (Golden State Medical Supply), QUETIAPINE FUMARATE (Golden State Medical Supply), QUETIAPINE FUMARATE (Ingenus Pharmaceuticals), QUETIAPINE FUMARATE (Lupin Pharmaceuticals), QUETIAPINE FUMARATE (Lupin Pharmaceuticals), QUETIAPINE FUMARATE (Macleods Pharmaceuticals Limited), QUETIAPINE FUMARATE (Major Pharmaceuticals), QUETIAPINE FUMARATE (Major Pharmaceuticals), QUETIAPINE FUMARATE (NCS HealthCare of KY), QUETIAPINE FUMARATE (NorthStar Rx LLC), QUETIAPINE FUMARATE (NuCare Pharmaceuticals), QUETIAPINE FUMARATE (NuCare Pharmaceuticals), QUETIAPINE FUMARATE (NuCare Pharmaceuticals), QUETIAPINE FUMARATE (NuCare Pharmaceuticals), QUETIAPINE FUMARATE (NuCare Pharmaceuticals), QUETIAPINE FUMARATE (NuCare Pharmaceuticals), QUETIAPINE FUMARATE (PD-Rx Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Preferred Pharmaceuticals), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Proficient Rx LP), QUETIAPINE FUMARATE (Quality Care Products), QUETIAPINE FUMARATE (Quality Care Products), QUETIAPINE FUMARATE (Quallent Pharmaceuticals Health LLC), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (REMEDYREPACK), QUETIAPINE FUMARATE (RPK Pharmaceuticals), QUETIAPINE FUMARATE (Rising Pharma Holdings), QUETIAPINE FUMARATE (Sun Pharmaceutical Industries), QUETIAPINE FUMARATE (Unichem Pharmaceuticals (USA)), QUETIAPINE FUMARATE (West-Ward Pharmaceuticals Corp), QUETIAPINE FUMARATE (XLCare Pharmaceuticals), QUETIAPINE FUMARATE ER (Direct_Rx), QUETIAPINE FUMARATE ER (Direct_Rx), QUETIAPINE FUMARATE ER (Direct_Rx), QUETIAPINE FUMARATE ER (Direct_Rx)
組成式   
(C21H25N3O2S)2. C4H4O4
質量    
882.3445
分子量   
883.0864
構造式   
クラス   
精神神経系用薬
 DG01478  ドパミン拮抗薬
  DG01474  ドパミンD2-受容体拮抗薬
 DG03200  抗精神病薬
  DG03064  非定型抗精神病薬
抗アレルギー薬
 DG01557  ヒスタミン受容体拮抗薬
  DG01482  ヒスタミンH1受容体拮抗薬
代謝酵素基質薬
 DG01633  CYP3A/CYP3A4基質薬
  DG02913  CYP3A4基質薬
コード   
薬効分類: 1179
ATCコード: N05AH04
化学構造グループ: DG00899
商品 (DG00899): D00458<JP/US>
効能    
統合失調症治療薬
  疾患
統合失調症 [DS:H01649]
双極性障害におけるうつ症状 [DS:H01653]
コメント  
多元受容体標的化抗精神病薬 (MARTA)
ベンゾジアゼピン系抗精神病薬
ターゲット 
HTR2A [HSA:3356] [KO:K04157]
DRD2 [HSA:1813] [KO:K04145]
  パスウェイ
hsa04080  神経刺激性リガンドとレセプターの相互作用
hsa04726  セロトニン作動性シナプス
hsa04728  ドーパミン作動性シナプス
代謝    
Enzyme: CYP3A4 [HSA:1576]
相互作用  

構造マップ 
map07213  ドパミン受容体の作動薬と拮抗薬
階層分類  
医療用医薬品の薬効分類 [BR:jp08301]
 1  神経系及び感覚器官用医薬品
  11  中枢神経系用薬
   117  精神神経用剤
    1179  その他の精神神経用剤
     D00458  クエチアピンフマル酸塩 (JP18)
医療用医薬品のATC分類 [BR:jp08303]
 N 神経系
  N05 精神抑制薬
   N05A 統合失調症薬
    N05AH ジアゼピン、オクサゼピン、チアゼピン、オキセピン
     N05AH04 クエチアピン
      D00458  クエチアピンフマル酸塩 (JP18) <JP/US>
医療用医薬品のUSP分類 [BR:jp08302]
 抗うつ薬
  抗うつ薬, その他
   クエチアピン
    D00458  クエチアピンフマル酸塩 (JP18)
 抗精神病薬
  第2世代/非定型
   クエチアピン
    D00458  クエチアピンフマル酸塩 (JP18)
 双極性障害治療薬
  双極性障害治療薬, その他
   クエチアピン
    D00458  クエチアピンフマル酸塩 (JP18)
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01478  ドパミン拮抗薬
   DG01474  ドパミンD2-受容体拮抗薬
    DG00899  クエチアピン
     D00458  クエチアピンフマル酸塩
  DG03200  抗精神病薬
   DG03064  非定型抗精神病薬
    DG00899  クエチアピン
     D00458  クエチアピンフマル酸塩
 抗アレルギー薬
  DG01557  ヒスタミン受容体拮抗薬
   DG01482  ヒスタミンH1受容体拮抗薬
    DG00899  クエチアピン
     D00458  クエチアピンフマル酸塩
 代謝酵素基質薬
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00899  クエチアピン
     D00458  クエチアピンフマル酸塩
医薬品クラス [BR:jp08332]
 抗アレルギー薬
  DG01482  ヒスタミンH1受容体拮抗薬 [商品一覧]
   D00458  クエチアピンフマル酸塩
ターゲットに基づく医薬品分類 [BR:jp08310]
 Gタンパク質共役受容体
  ロドプシンファミリー
   ドパミン
    DRD2
     D00458  クエチアピンフマル酸塩 (JP18) <JP/US>
   セロトニン
    HTR2A
     D00458  クエチアピンフマル酸塩 (JP18) <JP/US>
日本薬局方収載医薬品 [BR:jp08311]
 化学薬品等
  D00458  クエチアピンフマル酸塩
  D00458  クエチアピンフマル酸塩錠
  D00458  クエチアピンフマル酸塩細粒
日本の新薬 [jp08318.html]
 新有効成分含有医薬品
  D00458
薬物代謝酵素とトランスポーター [jp08309.html]
 薬物代謝酵素
  D00458
医薬品グループ [BR:jp08330]
 精神神経系用薬
  DG01478  ドパミン拮抗薬
   DG01474  ドパミンD2-受容体拮抗薬
    DG00899  クエチアピン
  DG03200  抗精神病薬
   DG03064  非定型抗精神病薬
    DG00899  クエチアピン
 抗アレルギー薬
  DG01557  ヒスタミン受容体拮抗薬
   DG01482  ヒスタミンH1受容体拮抗薬
    DG00899  クエチアピン
 代謝酵素基質薬
  DG01633  CYP3A/CYP3A4基質薬
   DG02913  CYP3A4基質薬
    DG00899  クエチアピン
リンク   
CAS: 111974-72-2
PubChem: 7847524
LigandBox: D00458
日化辞: J388.154G

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Ontology (9)   
   KEGG BRITE (9)   
Pathway (1)   
   KEGG PATHWAY (1)   
Disease (2)   
   KEGG DISEASE (2)   
Drug (3)   
   KEGG DGROUP (1)   
   LigandBox (1)   
   SIDER (1)   
Chemical substance (3)   
   PubChem (1)   
   ChEBI (1)   
   NIKKAJI (1)   
Gene (4)   
   KEGG ORTHOLOGY (2)   
   KEGG GENES (2)   
All databases (22)   

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