KEGG   Desmodus rotundus (common vampire bat): 112322497
Entry
112322497         CDS       T05907                                 
Symbol
KDM6A
Name
(RefSeq) lysine-specific demethylase 6A isoform X1
  KO
K11447  lysine-specific demethylase 6A [EC:1.14.11.68]
Organism
dro  Desmodus rotundus (common vampire bat)
Pathway
dro05202  Transcriptional misregulation in cancer
Brite
KEGG Orthology (KO) [BR:dro00001]
 09160 Human Diseases
  09161 Cancer: overview
   05202 Transcriptional misregulation in cancer
    112322497 (KDM6A)
 09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins [BR:dro03036]
    112322497 (KDM6A)
Enzymes [BR:dro01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.68  [histone H3]-trimethyl-L-lysine27 demethylase
     112322497 (KDM6A)
Chromosome and associated proteins [BR:dro03036]
 Eukaryotic type
  Histone modification proteins
   HMT complexes
    MLL3/MLL4 complex
     112322497 (KDM6A)
   Histone demethylases
    112322497 (KDM6A)
SSDB
Motif
Pfam: KDM6_C-hel JmjC KDM6_GATAL TPR_1 TPR_17 TPR_8 TPR_2 TPR_16 TPR_12 TPR_19 TPR_7 TPR_11 TPR_9 ANAPC8 TPR_15 ANAPC3
Other DBs
NCBI-GeneID: 112322497
NCBI-ProteinID: XP_024435871
Position
Unknown
AA seq 1198 aa
MFKVNTDYESSLKHFQLALVDCNPCTLSNAEIQFHIAHLYETQRKYYSAKEAYEQLLQTE
NLSAQVKATVLQQLGWMHHTIDLLADKATKENYAIQYLQKSLEADPNSGQSWYFLGRCYS
SIGKVQDAFISYRQSIDKSEASADTWCSIGVLYQQQNQPMDALQAYICAVQLDHGHAAAW
MDLGTLYESCNQPQDAIKCYLNATRSKSCSNTSALAARIKYLQACKPHHPNTEPVLGLSQ
TPILQQSLPVHMIHSSPVDGLSSPAKRKRTSSPTKNTSDNWSSGHAVSHPPVQQQTHSWC
LTPQKLQMRQTGVAQVRSTGIPNGPTADSSLPTNSVSGQQPQLALTRVPSVSQPGVRPAC
PGQPLANGPFSAGHVPCSTSRTLESTDTILIGNNHITGSGSNGNVPYPQRNALTLPHNRT
NLTSSAEEPWKNQLSNSTQGLHKGQSSHLAGPNGERPLSSTGPSQHLQAAGSGIQNQNGH
PTLPSNSVTQGAALNHLSSHTATSGGQQGITLTKESKPSGNTSTVPETSRHAGETPNSTA
SVEGLPNHVHQVTDAVCSPSHGDSKSPGLLSSDNPQLSALLMGKANNNVGTGTCDKVNNI
HPTVHTKTDNSVASSPSSAISTATPSPKSTEQTTTNSVTSLNSPHSGLHTINGEGMEESQ
SPMKTDLLLISHKPSPQIIPSLSVSIYPSSAEVLKACRNLGKNGLSNSSILLDKCPPPRP
PSSPYPPLPKDKLNPPTPSIYLENKRDAFFPPLHQFCTNPNNPVTVIRGLAGALKLDLGL
FSTKTLVEANNEHMVEVRTQLLQPADENWDPTGTKKIWRCESNRSHTTIAKYAQYQASSF
QESLREENEKRSHHKEHSDSESTSSDNSGRRRKGPFKTIKFGTNIDLSDDKKWKLQLHEL
TKLPAFVRVVSAGNLLSHVGHTILGMNTVQLYMKVPGSRTPGHQENNNFCSVNINIGPGD
CEWFVVPEGYWGVLNDFCEKNNLNFLMGSWWPNLEDLYEANVPVYRFIQRPGDLVWINAG
TVHWVQAVGWCNNIAWNVGPLTACQYKLAVERYEWNKLQSVKSIVPMVHLSWNMARNIKV
SDPKLFEMIKYCLLRTLKQCQTLREALIAAGKEIIWHGRTKEEPAHYCSICEVEVFDLLF
VTNESISRKTYVVHCQDCARKTSRNLENFVVLEQYKMEDLMQVYDQFTLAPPLPSSSS
NT seq 3597 nt   +upstreamnt  +downstreamnt
atgttcaaagtgaacacagactatgagtctagtttaaagcattttcagttagctttggtt
gactgtaatccctgcactttgtccaatgctgaaattcaatttcacattgcccacttatat
gaaacccagaggaagtattattctgcaaaggaagcttatgaacaacttttgcagacagaa
aacctgtctgcacaagtgaaagcaactgtcttgcaacagttaggttggatgcatcacact
atagatctcctggcagataaagccaccaaggaaaactatgctattcagtatctccagaag
tccttggaagcagatcctaattctggccagtcctggtatttccttggaaggtgctattca
agtattgggaaagttcaggatgcctttatatcttacaggcagtctattgataaatcagaa
gcaagtgcagatacatggtgttcaataggtgtgctatatcagcagcaaaatcagcctatg
gatgctttacaggcctatatttgtgctgtacaattggaccacggccatgctgcagcctgg
atggacctaggcacactctatgaatcctgcaaccagcctcaggatgccattaaatgctac
ttaaatgcaaccagaagcaaaagttgtagtaatacctctgcacttgcagcacgaattaag
tatttacaggcatgtaaacctcatcatccaaatacagaacctgtattaggcctcagtcaa
acaccaattttacagcaatccttgccagtacacatgattcattctagcccagtagatgga
ctgtccagccctgcgaagaggaaaagaacatctagtccaacaaagaatacttctgataat
tggagtagtggccatgcagtgtcacatcctccagtacagcaacaaactcattcatggtgt
ttgacaccacagaaattacagatgagacagacaggagttgcacaggtacgatctactgga
attcctaacgggccaacagctgactcatcactgcctacaaactcagtctctggccagcag
ccacagcttgctctgactagagtgcctagcgtctctcagcctggagtccgccctgcctgc
cctgggcagcctttggccaatggacccttttctgcaggccatgttccctgtagcacatca
agaacgctggaaagtacagacactattttgataggcaataatcacataacaggaagtgga
agtaatggaaacgtgccttacccgcagcgaaacgcactcactctacctcataaccgcaca
aacctgaccagcagcgcagaggagccgtggaaaaaccaactatctaactccactcagggg
cttcacaaaggtcagagttcacatttggcaggtcctaatggtgaacgacctctctcttcc
actgggccttcccagcatctccaggcagctggctctggtattcagaatcagaatggacat
cccaccctgcctagcaattcagtaacacagggggctgctctcaatcacctctcctctcac
actgctacctcaggtggacaacaaggcattaccttaaccaaagagagcaagccttcagga
aacacatcaacggtgcctgaaacaagtaggcacgctggagagacacctaacagcactgcc
agtgtcgagggacttcctaatcatgtccatcaggtgacagatgctgtttgcagtcctagc
catggagattcaaagtcaccaggtttactaagttcagacaatcctcagctctctgccttg
ttgatgggaaaagccaataacaatgtgggtactggaacctgtgacaaagtcaataacatc
cacccaactgttcatacaaagactgataattctgttgcctcttcaccgtcttcagccatt
tccacagcaacaccttctccaaaatccactgagcagacaaccacaaacagtgttaccagc
cttaacagtcctcacagtgggctacacacaattaatggagaagggatggaggaatctcag
agtcccatgaaaacagatctgcttctgattagtcacaaacctagtcctcagatcatacca
tcattgtctgtgtccatataccccagctcggcagaagttctgaaggcatgcaggaatcta
ggtaaaaatggcttatctaacagtagcattttattggataagtgtccgcctccaagacca
ccatcttcaccatacccgcccttgccaaaggacaagttgaatccacctacacctagtatt
tatttggaaaataaacgtgatgctttctttcctccattacatcaattttgtacaaatcca
aacaaccctgttacagtaatacgtggccttgctggagctctgaagttggacctaggactt
ttctctaccaaaactttggtggaagctaacaatgaacatatggtggaagtgaggacacag
ttgttgcagccagcagatgaaaattgggatcccactggaacaaagaaaatctggcgttgt
gaaagtaatagatctcatactacaattgctaagtatgcacagtaccaggcttcctccttc
caggaatcattgagagaagaaaatgagaaaagaagtcaccataaagagcactcagatagt
gaatctacatcttcagataattctgggaggaggaggaaaggaccttttaaaaccataaag
tttgggaccaacattgacctgtctgatgacaaaaagtggaagttgcagctacatgagctg
actaaacttcctgctttcgtgcgtgttgtatcagcaggaaatcttctaagccacgttggt
cataccatactaggcatgaacacagttcaactatacatgaaagttccaggaagcaggaca
ccgggtcatcaagaaaacaacaacttctgttcagttaacataaatatcggtccaggtgac
tgtgaatggttcgttgttcctgaaggttactggggtgttctgaatgatttctgtgaaaaa
aataatttgaatttcctaatgggttcttggtggcccaaccttgaagatctttatgaagca
aatgttccagtatataggtttattcaacgacctggagatttggtctggataaacgcaggc
actgtgcactgggttcaggctgttggctggtgcaacaacattgcttggaatgttggtcca
cttacagcctgccagtataagttggcagtggaacggtacgaatggaacaaattgcaaagt
gtgaagtcaatagtacccatggttcatctttcctggaatatggcacgaaatatcaaggtc
tcagatccaaagctttttgaaatgattaagtattgtcttctaagaactctgaagcaatgt
cagacgttgagggaagctctcattgctgcaggaaaagagattatatggcatgggcggaca
aaagaagaaccggctcattattgtagcatttgtgaggtggaggtttttgatctgcttttt
gttactaatgagagcatttctcgaaagacctacgtagtgcattgccaagattgtgcacga
aaaacaagcagaaacctggaaaattttgtggtgctagaacagtacaagatggaggacctg
atgcaagtctatgatcaatttacattagctcctccattaccatcttcctcatcttga

  All links  
Ontology (3)   
   KEGG BRITE (3)   
Pathway (1)   
   KEGG PATHWAY (1)   
Chemical reaction (1)   
   KEGG ENZYME (1)   
Genome (1)   
   KEGG GENOME (1)   
Gene (3)   
   KEGG ORTHOLOGY (1)   
   NCBI-PROTEINID (1)   
   NCBI-Gene (1)   
Protein sequence (8)   
   RefSeq(pep) (8)   
DNA sequence (8)   
   RefSeq(nuc) (8)   
Protein domain (16)   
   Pfam (16)   
All databases (41)   

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