KEGG   ENZYME: 1.1.1.290
Entry
EC 1.1.1.290                Enzyme                                 
Name
4-phosphoerythronate dehydrogenase;
PdxB;
PdxB 4PE dehydrogenase;
4-O-phosphoerythronate dehydrogenase;
4PE dehydrogenase;
erythronate-4-phosphate dehydrogenase
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
4-phospho-D-erythronate:NAD+ 2-oxidoreductase
Reaction(IUBMB)
4-phospho-D-erythronate + NAD+ = (3R)-3-hydroxy-2-oxo-4-phosphooxybutanoate + NADH + H+ [RN:R04210]
Reaction(KEGG)
R04210
Substrate
4-phospho-D-erythronate [CPD:C03393];
NAD+ [CPD:C00003]
Product
(3R)-3-hydroxy-2-oxo-4-phosphooxybutanoate [CPD:C06054];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
This enzyme catalyses a step in a bacterial pathway for the biosynthesis of pyridoxal 5'-phosphate. The enzyme contains a tightly-bound NAD(H) cofactor that is not re-oxidized by free NAD+. In order to re-oxidize the cofactor and restore enzyme activity, the enzyme catalyses the reduction of a 2-oxo acid (such as 2-oxoglutarate, oxaloacetate, or pyruvate) to the respective (R)-hydroxy acid [6]. cf. EC 1.1.1.399, 2-oxoglutarate reductase.
History
EC 1.1.1.290 created 2006, modified 2016
Pathway
ec00750  Vitamin B6 metabolism
ec01100  Metabolic pathways
Orthology
K03473  erythronate-4-phosphate dehydrogenase
Genes
ECOb2320(pdxB)
ECJJW2317(pdxB)
ECDECDH10B_2482(pdxB)
EBWBWG_2094(pdxB)
ECOKECMDS42_1891(pdxB)
ECEZ3582(pdxB)
ECSECs_3204(pdxB)
ECFECH74115_3460(pdxB)
ETWECSP_3195(pdxB)
ELXCDCO157_2968
EOIECO111_3068(pdxB)
EOJECO26_3308(pdxB)
EOHECO103_2784(pdxB)
ECOOECRM13514_3079(pdxB)
ECOHECRM13516_3022(pdxB)
ESLO3K_07895
ESOO3O_17740
ESMO3M_07845
ECKEC55989_2564(pdxB)
ECGE2348C_2460(pdxB)
EOKG2583_2857(pdxB)
ELRECO55CA74_14160
ELHETEC_2456
ECWEcE24377A_2614(pdxB)
EUNUMNK88_2871
ECPECP_2359
ENAECNA114_2411(pdxB)
ECOSEC958_2655(pdxB)
ECVAPECO1_4244(pdxB)
ECOAAPECO78_15420
ECXEcHS_A2471(pdxB)
ECMEcSMS35_2476(pdxB)
ECYECSE_2629
ECRECIAI1_2397(pdxB)
ECQECED1_2784(pdxB)
EUMECUMN_2660(pdxB)
ECTECIAI39_2469(pdxB)
EOCCE10_2705(pdxB)
EBRECB_02245(pdxB)
EBLECD_02245(pdxB)
EBEB21_02205(pdxB)
EBDECBD_1339
ECIUTI89_C2605(pdxB)
EIHECOK1_2553(pdxB)
ECZECS88_2468(pdxB)
ECCc2865(pdxB)
ELOEC042_2561(pdxB)
ELNNRG857_11750
ESEECSF_2197
ECLEcolC_1332
EKOEKO11_1445
EKFKO11_11095(pdxB)
EABECABU_c26530(pdxB)
EDHEcDH1_1336
EDJECDH1ME8569_2258(pdxB)
ELUUM146_05210
ELWECW_m2509(pdxB)
ELLWFL_12285(pdxB)
ELCi14_2663(pdxB)
ELDi02_2663(pdxB)
ELPP12B_c2413(pdxB)
ELFLF82_1606(pdxB)
ECOLLY180_12020
ECOIECOPMV1_02479(pdxB)
ECOJP423_12935
EFEEFER_0843(pdxB)
EALEAKF1_ch3652(pdxB)
EMAC1192_00265
ESZFEM44_01780(pdxB)
STYSTY2601(pdxB)
STTt0494(pdxB)
SEXSTBHUCCB_5320
SENTTY21A_02515
STMSTM2370(pdxB)
SEOSTM14_2918(pdxB)
SEVSTMMW_23921
SEYSL1344_2339(pdxB)
SEMSTMDT12_C23920
SEJSTMUK_2400(pdxB)
SEBSTM474_2469(pdxB)
SEFUMN798_2558(pdxB)
SETUSTU288_08235
SETCCFSAN001921_04935
SENRSTMDT2_23391(pdxB)
SENDDT104_24261(pdxB)
SENICY43_12685
SEENSE451236_18055
SPTSPA0494(pdxB)
SEKSSPA0458
SPQSPAB_00600
SEISPC_1335(pdxB)
SECSCH_2372(pdxB)
SEHSeHA_C2612(pdxB)
SHBSU5_02965
SENHCFSAN002069_19995
SEEHSEEH1578_21125
SEESNSL254_A2558(pdxB)
SENNSN31241_34770
SEWSeSA_A2600
SEASeAg_B2512(pdxB)
SENSQ786_11700
SEDSeD_A2721(pdxB)
SEGSG2400(pdxB)
SELSPUL_0515(pdxB)
SEGASPUCDC_0515(pdxB)
SETSEN2352(pdxB)
SENAAU38_11900
SENOAU37_11915
SENVAU39_11910
SENQAU40_13330
SENLIY59_12235
SENJCFSAN001992_21730
SEECCFSAN002050_18785
SEEBSEEB0189_007720
SEEPI137_02365
SENBBN855_24560(pdxB)
SENEIA1_11825
SENCSEET0819_18950
SESSARI_00529
SBGSBG_2152(pdxB)
SBZA464_2485
SALZEOS98_07160(pdxB)
SFLSF2396(pdxB)
SFXS2531(pdxB)
SFVSFV_2389(pdxB)
SFESFxv_2641(pdxB)
SFNSFy_3405
SFSSFyv_3479
SFTNCTC1_02631(pdxB)
SSNSSON_2378(pdxB)
SBOSBO_2357(pdxB)
SBCSbBS512_E2698(pdxB)
SDYSDY_2519(pdxB)
SDZAsd1617_03391
SHQA0259_15420
ENCECL_03669
ENLA3UG_16230
ECLGEC036_31560
ECLEECNIH2_16200
ECLNECNIH4_06970
ECLIECNIH5_15140
ECLXLI66_15540
ECLYLI62_17040
ECLZLI64_14975
EHMAB284_09880
EXFBFV63_15360
ECLAECNIH3_15235
ECLCECR091_15170
EAUDI57_03540
EKBBFV64_15885
ENOECENHK_15680
EECEcWSU1_03199(pdxB)
ELGBH714_12035
ECANCWI88_06585
ERNBFV67_15530
ECLSLI67_016785
ECHGFY206_17345(pdxB)
ESHC1N69_16040
ENTEnt638_2869
EASEntas_3041
ENRH650_07500
ENXNI40_015770
ENFAKI40_1530
LNICWR52_19360(pdxB)
EBGFAI37_13435(pdxB)
ENDA4308_20340
ENZG0034_16280(pdxB)
ENSHWQ15_01070(pdxB)
ENKLOC22_03680(pdxB)
EHUD5067_0007090(pdxB)
EMORL6Y89_15360(pdxB)
ESAESA_00896
CSKES15_1152(pdxB)
CSZCSSP291_04545
CSJCSK29544_02205
CCONAFK62_13600
CDMAFK67_14380
CSIP262_01768
CMJAFK66_005885
CUIAFK65_13875
CMWAFK63_04440
CTUCTU_29480(pdxB)
KPNKPN_02710(pdxB)
KPUKP1_3959(pdxB)
KPMKPHS_37790
KPPA79E_1390
KPHKPNIH24_09775
KPZKPNIH27_18055
KPVKPNIH29_18865
KPWKPNIH30_19085
KPYKPNIH31_18040
KPGKPNIH32_19415
KPCKPNIH10_18435
KPQKPR0928_18455
KPTVK055_4803
KPOKPN2242_16645
KPRKPR_1996(pdxB)
KPJN559_1541
KPID364_13805
KPAKPNJ1_01628
KPSKPNJ2_01597
KPXPMK1_00207(pdxB)
KPBFH42_09665
KPNEKU54_007510
KPNULI86_07515
KPNKBN49_3927(pdxB)
KVAKvar_1344
KPEKPK_1434(pdxB)
KPKA593_03410
KVDKR75_01070
KVQSP68_07600
KOXKOX_26590
KOEA225_4220
KOYJ415_11035
KOMHR38_24720
KMIVW41_15825
KOKKONIH1_20800
KOCAB185_15525
KQUAVR78_22855
EAEEAE_24600
EARCCG28899
KQVB8P98_08195
KLLBJF97_20765
KLWDA718_08225(pdxB)
KARLGL98_07200(pdxB)
KGRJJJ10_07955(pdxB)
RORRORB6_00955
RONTE10_20465
RPLNB1209_07100
RAODSD31_07315
RTGNCTC13098_01933(pdxB)
REEelectrica_01430(pdxB)
CROROD_27321(pdxB)
CKOCKO_00466
CFDCFNIH1_23150
CBRAA6J81_24605
CWECO701_06300
CYOCD187_07555
CPOTFOB25_18690(pdxB)
CFQC2U38_17100
CSEDJY391_07230(pdxB)
CAMAF384_12405
CAFAL524_10515
CIFAL515_16045
CFARCI104_17745
CIRC2U53_27565
CIEAN232_12215
CPARCUC49_12100
CTELGBC03_12715(pdxB)
CITZE4Z61_00790(pdxB)
CARSE1B03_18575(pdxB)
BFLBfl497(pdxB)
BPNBPEN_513(pdxB)
BVABVAF_498(pdxB)
BCHRBCHRO640_528(pdxB)
BEDBTURN675_492(pdxB)
BECGN160_03025
HDEHDEF_0780(pdxB)
SECTA359_06950
SEHCA35E_00422
RIPRIEPE_0503
RIGAOQ88_01905
EBTEBL_c12270(pdxB)
CNTJT31_19265
CEMLH23_21825
CENLH86_20410
CLAPNCTC11466_01265(pdxB)
PGELG71_11650
ESCEntcl_1405
KLEAO703_14850
KSAC813_22965
KORAWR26_07895(pdxB)
KRDA3780_16090
KCOBWI95_21195
KOTEH164_06975(pdxB)
KPSEIP581_15795(pdxB)
KGOCEW81_07405
KIENCTC12125_00351(pdxB_1)
KASKATP_13520(pdxB)
ICPICMP_098(pdxB)
LAXAPT61_06675
LEIC2U54_20960
LEHC3F35_18810
LEEDVA44_06800
LERGNG29_15960(pdxB)
LEAGNG26_15810(pdxB)
LPNUKQ929_05830(pdxB)
LAZA8A57_14915
LEFLJPFL01_2942
LEWDAI21_11730
BUFD8682_22450(pdxB)
BAGEBADSM9389_12260(pdxB)
BFTMNO13_06755(pdxB)
SBWTGUWTKB_2040(pdxB)
GEDFVIR_GE00190(pdxB)
SYMK6K13_14165(pdxB)
METYMRY16398_15800(pdxB)
AHNNCTC12129_01487(pdxB)
ASUBNLZ15_15535(pdxB)
YREHEC60_11015(pdxB)
SGOEA8O29_006900(pdxB)
KINAB182_06755
PDZHHA33_09820(pdxB)
IZHFEM41_22550(pdxB)
SNYKEC38_00390
PSHISAMEA2665130_0931(pdxB)
PSGCG163CM_03230(pdxB)
EBFD782_1343
EBCC2U52_17285
EBUCUC76_22815
PSTSE05_22910(pdxB)
YPEYPO2763(pdxB)
YPKy1597(pdxB)
YPHYPC_1517(pdxB)
YPAYPA_2080
YPNYPN_2183
YPMYP_2400(pdxB)
YPPYPDSF_1997
YPGYpAngola_A0364(pdxB)
YPZYPZ3_2541(pdxB)
YPTA1122_12220
YPDYPD4_2526(pdxB)
YPXYPD8_2521(pdxB)
YPWCH59_3650(pdxB)
YPJCH55_23(pdxB)
YPVBZ15_762(pdxB)
YPLCH46_2338(pdxB)
YPSYPTB2620(pdxB)
YPOBZ17_4019(pdxB)
YPIYpsIP31758_1418(pdxB)
YPYYPK_1527
YPBYPTS_2715
YPQDJ40_3924(pdxB)
YPUBZ21_1916(pdxB)
YPRBZ20_3590(pdxB)
YPCBZ23_2200(pdxB)
YPFBZ19_1980(pdxB)
YENYE1307(pdxB)
YEPYE105_C2799
YEYY11_01761
YELLC20_03733
YEWCH47_724(pdxB)
YETCH48_348
YEFFORC2_1357
YEEYE5303_11011(pdxB)
YSIBF17_22555
YALAT01_1217(pdxB)
YFRAW19_1897(pdxB)
YINCH53_414(pdxB)
YKRCH54_3888
YROCH64_1235(pdxB)
YRUBD65_879(pdxB)
YRBUGYR_04965
YAKACZ76_02665
YMADA391_07085
YHID5F51_05045(pdxB)
YCAF0T03_07490(pdxB)
YMOHRD69_12230(pdxB)
SMARSM39_2939(pdxB)
SMACSMDB11_2736(pdxB)
SMWSMWW4_v1c34510
SPESpro_3336
SRRSerAS9_3534
SRLSOD_c32520(pdxB)
SRYM621_17685
SPLYQ5A_017650(pdxB)
SRSSerAS12_3535
SRASerAS13_3536
SSZSCc_491(pdxB)
SMAFD781_3133
SLQM495_17140
SERFL085_11425
SERSSERRSCBI_16750
SFWWN53_25925
SFGAV650_21725
SRZAXX16_1939
SERASer39006_010295
SERQCWC46_10290
SERMCLM71_16560
SQUE4343_24080(pdxB)
SFJSAMEA4384070_3461(pdxB)
SOFNCTC11214_03334(pdxB_2)
SSURATE40_013880
SURIJ0X03_06785(pdxB)
SRHZFO014_17680(pdxB)
SENPKHA73_16845(pdxB)
SFOZ042_03560
RAHRahaq_1226
RACEJHW33_00640(pdxB)
RAQRahaq2_1300
ROXBV494_01445
RVCJ9880_13955(pdxB)
GQUAWC35_19570
FSMCCS41_04020
EAMEGXP68_06520(pdxB)
RBADH2866_01680(pdxB)
ECAECA3060(pdxB)
PATREV46_15130
PATOGZ59_30650(pdxB)
PCTPC1_2802
PCCPCC21_028720
PCVBCS7_14305
PWAPecwa_1463
PPARA8F97_11450
PECW5S_1347
PWSA7983_01045
PPOABJK05_09240
PBRAB5S52_07490
PPUJE2566_14635(pdxB)
PARII2D83_07410(pdxB)
PAQUDMB82_0007285(pdxB)
PVZOA04_30510(pdxB)
PPAVLOZ86_07550(pdxB)
PQUIG609_006395(pdxB)
DDDDda3937_02107(pdxB)
DZEDd1591_1366
DDCDd586_2775
DZCW909_13550
DSOA4U42_02045
CEDLH89_19635
DFNCVE23_14905
DDQDDI_2743
DAQDAQ1742_01321(pdxB)
DICDpoa569_001113(pdxB)
DDADd703_2578
BGJAWC36_03025
BRBEH207_11970(pdxB)
BNGEH206_06810(pdxB)
BIZHC231_07075(pdxB)
LBQCKQ53_16905
LPOPI6N93_11120(pdxB)
SGLSG1621
SODSant_1314(pdxB)
PESSOPEG_2879(pdxB)
SENYHBA_0615(pdxB)
SLIGGTU79_19260(pdxB)
EAMEAMY_2413(pdxB)
EAYEAM_2328(pdxB)
ETAETA_11670(pdxB)
EPYEpC_12230(pdxB)
EPREPYR_01301(pdxB)
EBIEbC_31130(pdxB)
ERJEJP617_34690(pdxB)
EGEEM595_2535(pdxB)
EPECI789_03165
ERWIGN242_06215(pdxB)
ETPLU633_17560
WBRpdxB
WGLWIGMOR_0465(pdxB)
PAMPANA_2672(pdxB)
PLFPANA5342_1382(pdxB)
PAJPAJ_1961(pdxB)
PAQPAGR_g1355
PVAPvag_2131(pdxB)
PAGGAL522_17685
PAOPat9b_2764
KLNLH22_08775
PANTPSNIH1_00170
PANPPSNIH2_04105
HHSHHS_05350(pdxB)
PCKBMSBPS_0161
PSTWDSJ_17250
PALHB1H58_13435
PANSFCN45_13385(pdxB)
PEYEE896_06050(pdxB)
PDISD8B20_11875(pdxB)
PERLAC65_10685(pdxB)
PGZC2E15_14645
PCDC2E16_14715
MINTC7M51_02132(pdxB)
MTHIC7M52_00708(pdxB)
TCIA7K98_13795
TPTYNCTC11468_02532(pdxB_2)
PLUplu3175(pdxB)
PLUMA4R40_15855
PAYPAU_01449(pdxB)
PTTVY86_00410
PAKHB0X70_16360
PLUICE143_16355
PMRPMI1792(pdxB)
PMIBBB2000_1898(pdxB)
PVLAOB99_10975
PVGCRN77_09945
PHAUPH4a_00715
PROTBTA34_10615
PCOLF1325_12560(pdxB)
PCIBF9282_12635(pdxB)
PPEEI6G31_15910(pdxB)
XBOXBJ1_2967(pdxB)
XBVXBW1_3113(pdxB)
XNEXNC1_3168(pdxB)
XNMXNC2_3046(pdxB)
XDOXDD1_2649(pdxB)
XPOXPG1_1201(pdxB)
XHOA9255_01500
XBUHGO23_07505(pdxB)
PSIS70_02545
PSXDR96_3677(pdxB)
PSTABGK56_05870
PRGRB151_026990(pdxB)
PALACO695_11650
PHEINCTC12003_01530(pdxB)
PRQCYG50_02565(pdxB)
PRJNCTC6933_02367(pdxB)
PVCG3341_07960(pdxB)
MMKMU9_2580
ASYAUT07_00336(pdxB)
AENARADI_0341(pdxB)
ANSArsFIN_26760(pdxB)
AEDE3U36_08215(pdxB)
AETLDL57_04795(pdxB)
MWIMNY66_09990(pdxB)
EICNT01EI_2722
ETRETAE_2417
ETDETAF_2187
ETEETEE_0444(pdxB)
ETCETAC_11445
EDWQY76_08275
EDLAAZ33_12605(pdxB)
EHOA9798_05110
HAVAT03_14935
HPARAL518_11300
OPODSM2777_18275
LPVHYN51_15250
PFQQQ39_12250
PRAGEKN56_06195(pdxB)
LRINCTC12151_02328(pdxB)
DTXATSB10_27970
VCHVC_2108
VCFIR04_15670
VCSMS6_1866
VCEVch1786_I1599(pdxB)
VCQEN18_13625
VCJVCD_002261
VCIO3Y_10175
VCOVC0395_A1692(pdxB)
VCRVC395_2222(pdxB)
VCMVCM66_2031(pdxB)
VCLVCLMA_A1842
VCXVAA049_775
VCZVAB027_2742
VVUVV1_1988
VVYVV2428
VVMVVMO6_00871
VVLVV93_v1c21310
VPAVP2193
VPBVPBB_2012
VPKM636_10955
VPFM634_13365
VPHVPUCM_2282
VHAVIBHAR_03104
VCAM892_15530
VAGN646_1296
VEXVEA_002871
VDBAL552_19545
VHRAL538_04845
VNAPN96_02895
VOWA9237_13110
VROBSZ04_12555
VSPVS_0900
VEJVEJY3_11295
VFUvfu_A01215
VNIVIBNI_A0800(pdxB)
VANVAA_03431
LAGN175_05450
VAUVANGNB10_cI1916c(pdxB)
VCYIX92_03630
VCTJV59_35095
VTUIX91_04570
VEUIXK98_13035
VSIMTO69_09330
VFLAL536_09935
VMIAL543_19840
VBRA6E01_08500
VSCVSVS12_02278(pdxB)
VGABSQ33_03995
VSHBSZ05_11485
VQICCZ37_09150
VTAA2166(pdxB)
VAFD1115_04685
VNLD3H41_11940
VCCFAZ90_04575
VASGT360_04535
VAQFIV01_10545(pdxB)
VSRVspart_02364(pdxB)
VKABTD91_02010
VZIG5S32_10500
VNVIF132_19855
VGIMID13_11065
VSLLTQ54_13290
VFIVF_1699(pdxB)
VFMVFMJ11_1825
VSAVSAL_I1072(pdxB)
AWDAWOD_I_1817(pdxB)
PPRPBPRA2656(PLU3175)
PGBH744_2c2796
PDSCAY62_09785
PGHFH974_11245
GHOAL542_05140
PMAICF386_00910
SALYE8E00_03325(pdxB)
SKSFCN78_09525
SCOTHBA18_10005
PAEPA1375(pdxB)
PAEVN297_1416(pdxB)
PAEIN296_1416(pdxB)
PAUPA14_46470(pdxB)
PAPPSPA7_4010(pdxB)
PAGPLES_38101(pdxB)
PAFPAM18_3533(pdxB)
PNCNCGM2_2268(pdxB)
PAEBNCGM1900_5199(pdxB)
PDKPADK2_18785
PSGG655_18305
PRPM062_07450
PAEPPA1S_19050
PAERPA1R_gp4977
PAEMU769_18895
PAELT223_19495
PAESSCV20265_4039
PAEUBN889_01612(pdxB)
PAEGAI22_15550
PAECM802_1413(pdxB)
PAEOM801_1415(pdxB)
PMYPmen_1908
PMKMDS_2990
PREPCA10_38090(pdxB)
PPSEBN5_2537(pdxB)
PFUWKF707C_18860
PALCA0T30_11885
PCQPcP3B5_29600(pdxB)
PMUIG4G71_18070(pdxB)
PPUPP_2117(pdxB)
PPFPput_3624
PPGPputGB1_1657
PPWPputW619_1634
PPTPPS_1680
PPBPPUBIRD1_3536
PPIYSA_01544
PPXT1E_0586(pdxB)
PPUHB479_08205
PPUTL483_07825
PPUNPP4_37320(pdxB)
PPUDDW66_1971
PFVPsefu_2844
PMONX969_06460
PMOTX970_06435
PMOSO165_004450
PPJRK21_03315
PORAPT59_09550
PMOLCLJ08_21540
PSTPSPTO_2019(pdxB)
PSBPsyr_1828
PSYRN018_08515
PSPPSPPH_1788
PSAVPSA3335_19830
PAMGBKM19_011450
PCIPCH70_16770
PAVLBKM03_19475
PVDCFBP1590__1886(pdxB)
PCABJGS08_17695(pdxB)
PCOFPOR16_08295(pdxB)
PTREI9H09_08925(pdxB)
PSYIMME58_09330(pdxB)
PFLPFL_1933(pdxB)
PPRCPFLCHA0_c19870(pdxB)
PPROPPC_2004
PFEPSF113_3995
PFNHZ99_08190
PFOPfl01_3886(pdxB)
PFSPFLU_1546(pdxB)
PFCPflA506_1560(pdxB)
PPZH045_04245
PFBVO64_4687
PMANOU5_5462(pdxB)
PTVAA957_06385
PCGAXG94_24670
PVRPverR02_07880
PAZOAYR47_14995
POIBOP93_07430
PRXHRH33_08385(pdxB)
PMEDE3Z27_09255(pdxB)
PFWPF1751_v1c15320(pdxB)
PFFPFLUOLIPICF700665
PFXA7318_06890
PENPSEEN3753(pdxB)
PLULFOB45_13015(pdxB)
PBAPSEBR_a1739
PBCCD58_09650
PPUUPputUW4_03530(pdxB)
PDRH681_11315
PSVPVLB_07790
PSKU771_08860
PKCPKB_2985(pdxB)
PCHEY04_09310
PCZPCL1606_41030
PCPJM49_20540
PFZAV641_08490
PLQAA042_01555
PALKPSAKL28_16150
PRHLT40_06095
PSWLK03_20310
PPVNJ69_04530
PSESPSCI_3672
PSEMTO66_09895
PSECCCOS191_3611(pdxB)
PPSYAOC04_05140
PSOSPOS17_1954
PKRAYO71_21295
PFKPFAS1_20900
PANRA7J50_1670
PPSLBJP27_00700
PSETTHL1_3787
PSILPMA3_08560
PYMAK972_4251
PADEC3B55_00719(pdxB)
PKEDLD99_19420
PALLUYA_14435
PUMHGP31_09355(pdxB)
POJPtoMrB4_33840(pdxB)
PGGFX982_02951
PPSHG5J76_11880(pdxB)
PGYAWU82_12055
PLALFXN65_18685(pdxB)
PSEJHNQ25_11075(pdxB)
PVKEPZ47_09445(pdxB)
PEZHWQ56_08465(pdxB)
PBZGN234_08840(pdxB)
PKHJLK41_15610(pdxB)
PTYJWV26_00480(pdxB)
PMAOPMYSY11_2516(pdxB)
PATAJWU58_09375(pdxB)
PDWBV82_3932(pdxB)
PZEHU754_020675(pdxB)
PMOEHV782_019870(pdxB)
PCAMHNE05_07160(pdxB)
PSEPC4K39_2034
PVWHU752_023720(pdxB)
PTRTHU722_0008720(pdxB)
PXAKSS93_11760(pdxB)
PSAMHU731_023530(pdxB)
PTZHU718_020855(pdxB)
PQIKH389_18670(pdxB)
PSHHHU773_019650(pdxB)
PXNHU772_008165(pdxB)
PHVHU739_000180(pdxB)
PPRGHU725_007525(pdxB)
PNNKEM63_10030(pdxB)
PANHHU763_008570(pdxB)
PASGKSS96_08360(pdxB)
PFAKKSS94_08420(pdxB)
PMUYKSS95_10925(pdxB)
PMAMKSS90_17780(pdxB)
PAZEKSS91_09145(pdxB)
PALVKSS97_10000(pdxB)
PPHABVH74_11495
PORYEJA05_08980(pdxB)
PWZJ7655_09315(pdxB)
PTKEXN22_19030(pdxB)
PTWTUM18999_22210(pdxB)
PZAHU749_010480(pdxB)
PIEHU724_019550(pdxB)
PWYHU734_017390(pdxB)
PTAENCTC10697_01627(pdxB)
PGFJ0G10_20890(pdxB)
PCAVD3880_13760(pdxB)
PJUL1P09_07790(pdxB)
PSAPST_1818(pdxB)
PSZPSTAB_1716(pdxB)
PSRPSTAA_1846(pdxB)
PSCA458_11740
PSJPSJM300_11275
PSHPsest_2548
PSTUUIB01_12930
PSTTCH92_08520
PSEDDM292_10375
PCHLLLJ08_12220(pdxB)
PBMCL52_08010
PKGLW136_10285(pdxB)
AVNAvin_29870
AVLAvCA_29870
AVDAvCA6_29870
ACXAchr_17990(pdxB)
PBBAKN87_05455
PAGRE2H98_02050
HPEGEAO82_10420(pdxB)
HAESLO767_09090(pdxB)
MAQMaqu_1775
MHCMARHY1531(pdxB)
MADHP15_2098(pdxB)
MBSMRBBS_2386(pdxB)
MSXAU14_00430
MPQABA45_11225
MARIACP86_00635
MLQASQ50_19960
MSQBKP64_03915
MARAD0851_03775(pdxB)
MARJMARI_14640(pdxB)
PARPsyc_0272
PCRPcryo_0298
PRWPsycPRwf_2208
PSOPSYCG_01725
PURAOC03_07960
PALIA3K91_0344
PSPGAK823_01775
PSYGAK825_01740
PSYCDABAL43B_0350(pdxB)
PSYAAOT82_1462
PSYYDLE54_10600
PSYPE5677_11725
ACBA1S_2637
ABMABSDF0843(pdxB)
ABYABAYE0853(pdxB)
ABCACICU_02881
ABNAB57_3051
ABBABBFA_00832(pdxB)
ABXABK1_2937
ABZABZJ_03067
ABRABTJ_00833
ABDABTW07_3103
ABHM3Q_3114
ABADABD1_25910(pdxB)
ABJBJAB07104_02973
ABABBJAB0715_03013
ABAJBJAB0868_02853
ABAZP795_3935
ABKLX00_14145
ABAUIX87_09695
ABAAIX88_16215
ABWBL01_05800
ABALABLAC_08580
ACCBDGL_002073(pdxB)
ANORR32_04570
ALCOTEC02_04375
ACALBUM88_15185
ASEII8T81_04515
ACDAOLE_04110
ACIACIAD2667(pdxB)
ATTAMQ28_03440
AEIAOY20_13180
AJORZ95_11135
ACWA0J50_04200
ACVAMD27_10895
AHLAHTJS_11310
AJNBVL33_13180
ASOLBEN76_01225
ALABFG52_12275
ASJAsACE_CH02006(pdxB)
AIDCTZ23_04860
ADVDJ533_07815
ARJDOM24_09740
AWUBEN71_06085
ACUMC9E88_016305 C9E88_17515
AGUAS4_30910(pdxB)
AUGURS_0059
ALWFOB21_05325
ADSFPL17_00450
ABERBSR55_14925
ATNFM020_04460
ACHICDG60_12565
ALJG8D99_04680
AWGGFH30_09235
ASHAG8E00_05245
ATGJ4G44_10815
AVBRYU24_09130(pdxB)
ABOUACBO_21720(pdxB)
AGYLFPL18_11860
ACIUA3K93_08445
MCTMCR_0409
MCSDR90_1495
MCATMC25239_00426(pdxB)
MOIMOVS_08580
MOSAXE82_09445
MBLAAX09_08345
MBOIDQF64_11190
MCUNNCTC10297_00922(pdxB)
MNNI6G26_10395
MBAHHYN46_04105
SONSO_3071(pdxB)
SDNSden_1483
SFRSfri_1392
SAZSama_2153
SBLSbal_2745
SBMShew185_2762
SBNSbal195_2839
SBPSbal223_1614
SBTSbal678_2848
SBSSbal117_2881
SBBSbal175_1608
SLOShew_2309
SPCSputcn32_2444
SHPSput200_2467
SSESsed_1649
SPLSpea_1612
SHEShewmr4_1423
SHMShewmr7_1488
SHNShewana3_1476
SHWSputw3181_1564
SHLShal_2644
SWDSwoo_2987
SWPswp_3119
SVOSVI_2880(pdxB)
SHFCEQ32_01475
SJASJ2017_2758
SPSWSps_01759
SBJCF168_13380
SMAVCFF01_07780
SHEWCKQ84_16580
SALGBS332_16070
SLJEGC82_14350
SMAIEXU30_02640
SPOLFH971_12695
SBKSHEWBE_2235(pdxB)
SKHSTH12_01889(pdxB)
SAESHBH39_06315(pdxB)
SLITJQC75_11035
SCAATUM17387_16830(pdxB)
SPSHFM037_18430
SEURFM038_008360
SYKKDN34_07170(pdxB)
SCYPJYB88_11135
SAVIJYB87_07070
SSEMJYB85_11315
SGLAFJ709_06175
SINVK8B83_10155
SXMMKD32_07455
SVMKDH10_001474
ILOIL1020(pdxB)
ILIK734_05130
IPICEW91_08495
IDICWC33_01365
IDTC5610_03695
IABK5X84_04055
CPSCPS_3806(pdxB)
COMCMT41_13255
COZA3Q34_04615
COLWA3Q33_13045
COLADBO93_04460
COVEKO29_15690
CBERB5D82_13035
LSDEMK97_17535
THTE2K93_13305
THAPFNC98_11160
PHAPSHAa2079(pdxB)
PTNPTRA_a2549(pdxB)
PATPatl_3364
PSMPSM_A2144(pdxB)
PSEOOM33_13045
PIAPI2015_2095
PPHEPP2015_2084
PBWD172_012910
PRRAT705_07140
PLZS4054249_17105
PALNB0W48_13275
PPISB1L02_11365
PEAPESP_a2709(pdxB)
PSPOPSPO_a2167(pdxB)
PARTPARC_a1191(pdxB)
PTUPTUN_a1303(pdxB)
PNGPNIG_a2751(pdxB)
PTDPTET_a2448(pdxB)
PSENPNC201_05480(pdxB)
PDJD0907_10645
PAGAPAGA_a1221(pdxB)
PCARPC2016_2203
PMAACPA52_04855
PXIJ5O05_03690
PVBJ5X90_00220
PSAZPA25_09810(pdxB)
PDVFFU37_03640
PSYMJ1N51_14315
AMCMADE_1011920
AMHI633_13040
AMAAamad1_12675
AMALI607_11945
AMAEI876_12320
AMAOI634_12175
AMADI636_12290
AMAII635_12655
AMAGI533_11910
AMACMASE_11690
AMBAMBAS45_12255
AMGAMEC673_12005
AMKAMBLS11_11500
ALTambt_05045
AALEP13_11990
ASPAOR13_1030
ASQAVL57_13480
AAWAVL56_12590
ALRDS731_13605
ALEAV939_12425
ALZAV940_12185
APELCA267_016455
SALMD0Y50_12310
SALKFBQ74_06515
SMAAIT774_05900
GAGGlaag_0986
GNIGNIT_2201(pdxB)
GPSC427_1425
PMESFX988_03565
LALAT746_05140
CATEC2869_17325
SALHHMF8227_01955(pdxB)
HMIsoil367_06795
PAEWKIH87_12280
AGZM0C34_12055
PINPing_1994
PSYPCNPT3_05885
FBLFbal_2614
FESHER31_10020
MVSMVIS_3050(pdxB)
MYAMORIYA_0114(pdxB)
MMAAFR932_03330
CJACJA_2376(pdxB)
CEBB0D95_02590
CELLCBR65_00560
CEKD0B88_10830
CEGD0C16_01655
SDESde_1159
TTUTERTU_1127(pdxB)
SAGAM5M_04150
MARQMARGE09_P2186
GILNHM04_06145
SPOIIMCC21906_02192
SNANI6N98_08450
ZALAZF00_09700
OSGBST96_18400
MTHDA3224_09590
MICCAUP74_02127(pdxB)
MAGAMag101_06400
MIIBTJ40_07810
MICTFIU95_13890(pdxB)
MHYDGTQ55_12395
MCELLPW13_08975
MICZGL2_28340(pdxB)
HJABST95_11990
HALCEY643_10415
KIMG3T16_02080
AFUSEYZ66_07215
CBUCBU_1812
CBSCOXBURSA331_A2011(pdxB)
CBDCBUD_0041(pdxB)
CBGCbuG_0185(pdxB)
CBCCbuK_0108(pdxB)
CEYCleRT_01320(pdxB)
CEAZ664_00245(pdxB)
CENDEGQ50_00240
CENOCEAn_00714
ALGAQULUS_17480(pdxB)
ASIPAQUSIP_19870(pdxB)
CEQB1F76_00245
LPNlpg0918
LPHLPV_1054(pdxB)
LPOLPO_1002(pdxB)
LPULPE509_02293
LPMLP6_0906(pdxB)
LPFlpl0949(pdxB)
LPPlpp0979(pdxB)
LPCLPC_2373(pdxB)
LPAlpa_01387
LPElp12_0940
LLOLLO_0860(pdxB)
LFALFA_0990(pdxB)
LHALHA_2190(pdxB)
LOKLoa_02119
LCDclem_04410(pdxB)
LSHCAB17_08635
LLG44548918_00815(pdxB)
LIBE4T55_13770
LGTE4T54_02605
LJRNCTC11533_00950(pdxB)
LCJNCTC11976_01656(pdxB)
LWASAMEA4504053_1250(pdxB)
LSSNCTC12082_00964(pdxB)
LADLNCTC12735_01469(pdxB)
LANTTUM19329_22870(pdxB)
LLYJ2N86_05550
TMCLMI_1161(pdxB)
TCXTcr_0451
HTREPV75_02860
HMARHVMH_1934(pdxB)
TCYThicy_1405
TAOTHIAE_09005
THIOAYJ59_10945
TMHJX580_06505
PSALPSLF89_1812
THIGFE785_08850
TXAHQN79_02890
TSETHMIRHAS_20340(pdxB)
TZOTHMIRHAT_06200(pdxB)
TIGTHII_2803
BLEPAL038_16885(pdxB)
THISHZT40_11035
TUNJ9260_06310
TLOJ9253_20555
RHHE0Z06_04960
HCHHCH_02292
HAHEENC22_10415(pdxB)
CSACsal_1346
HELHELO_2011(pdxB)
HCSFF32_11515
HAKKO116_03087
HAMHALO3327
HHUAR456_06105
HCOLOKO_02657(pdxB)
HSIBOX17_12885
HALOBWR19_13850
HHHCLM76_11905
HBEBEI_2431(pdxB)
HAGBB497_08770
HAFC8233_14610
HALKCUU95_00645
HVNEI420_05845(pdxB)
HOLHORIV_19950
HSRHSBAA_17940
HMDCTT34_05750
HAXIHAALTHF_47090n(pdxB)
HTTHZS52_21635(pdxB)
HCAMI4484_07425(pdxB)
HPIZGYM47_05410(pdxB)
HSXHNO51_06875(pdxB)
HSVHNO53_07585(pdxB)
HTXEKK97_08010(pdxB)
CMAIBFX80_03245
CAMHLCW13_13965(pdxB)
KUSB9G99_00835
KMAB9H00_14430
KUYFY550_10905(pdxB)
PAURFGL86_10440(pdxB)
ABOABO_1177(pdxB)
ADIB5T_01956(pdxB)
APACS7S_07500
ALNAS19_12460
AXEP40_09320
KAKKalk_02710
MMWMmwyl1_2280
MMEMarme_2180
MPCMar181_1685
MPRIMP3633_2049
MARDIBG28_09705
MFOIJSY38_00965
MPRFJ8N69_15700
TOLTOL_1953
TORR615_07980
OAIOLEAN_C22760(pdxB)
MARSA8C75_07250
MGEOCFI10_12070
MSECLN244_09670(pdxB)
BSANCHH28_13215
NCUF0U83_10875
NJPNEJAP_1243(pdxB)
NIKF5I99_05975(pdxB)
BMARHF888_09430(pdxB)
AJPAMJAP_1886(pdxB)
VCWGJQ55_07360(pdxB)
BACZKFF03_08790(pdxB)
GSNYC6258_02906
RFOREIFOR_01058(pdxB)
OMEOLMES_2273
LLPGH975_08930
ENWMJO57_20115(pdxB)
AHAAHA_2683
AHYAHML_14220
AHDAI20_06040
AHRV428_14715
AHPV429_14735
AHJV469_08375
AHHRY45_14090
AHIVU14_08335
AAJBOQ57_13740
ASAASA_2534(pdxB)
AEOO23A_p0919
AVRB565_1558
AVOAMS64_11540
AMEDB224_2948
ASRWL1483_196(pdxB)
ADHCK627_12420
ACAVVI35_12805
AEMCK911_05015
AEAC2U39_13195
ARVC7N77_12115
AESC2U30_00760
AELNCTC12917_02512(pdxB)
ASIMFE240_07750
AALLI6G90_07310
AJDI6H43_01995
ARIVKYK33_08550
TAUTola_1572
OCEGU3_11855
OCMCBP12_04170
OPFCBP31_14540
ZDFAN401_10915
KKOKkor_0966
KGETQ33_0790
KSDKS2013_831
KPDCW740_07790
TSNW908_06050
THINCRN91_04285
THOSP60_06845
PSPIPS2015_1425
RMARmag_0684
REOHUE58_03385
VOKCOSY_0635(pdxB)
EBHBSEPE_0452(pdxB)
BTHGMS2017_0687
BCIBCI_0363(pdxB)
BCIBIM45_817
GPBHDN1F_30210(pdxB)
IFOCVFO_1003(pdxB)
APHFCVPH_0817(pdxB)
PLGNCTC10937_03640(pdxB)
RTEAHK414_11515
SECHB18_18640
MAESGa0123461_1971
MFNGa0123462_0455
PARHI5S86_09080(pdxB)
VBSEGM51_10945
PBUL21SP3_01718(pdxB)
PBPSTSP1_01816(pdxB)
PBASSMSP2_00486(pdxB)
ALUSSTSP2_02328(pdxB)
VBLL21SP4_00557(pdxB)
TAERGT409_07245
VBCC5Q97_12350
TPXTurpa_4018
BTHBT_3361
BTHOBtheta7330_04939(pdxB)
BFRBF0222
BFSBF9343_0179(pdxB)
BFGBF638R_0171(pdxB)
BFBVU15_00450
BHLBache_0551
BOABovatus_03493(pdxB)
BCELBcellWH2_02474(pdxB)
BCACCGC64_04360
BCAEA4V03_19195
BZGC4H11_09540
BHFC3V43_10070
BISDXK01_003610(pdxB)
BUNBun01g_09740(pdxB)
BEGINE88_01682(pdxB)
BSTEK6V31_11285(pdxB)
BFEK6V30_05430(pdxB)
BNOK8P02_19300(pdxB)
BHUMJXR92_005015(pdxB)
BVUBVU_1060
BDOEL88_24500
BDHGV66_06460
PCOPI6J50_15360(pdxB)
PGIPG_1220
PGNPGN_1359
PGTPGTDC60_1193
PAHPoras_1717
PCRENCTC12858_00048(pdxB)
PCAGNCTC12856_01905(pdxB)
PENDLA319_04300
PSOECE91St14_15450(pdxB)
PBTING2E5B_1084(pdxB)
PMUCING2E5A_1462(pdxB)
PETPEIBARAKI_5426
PSACPSM36_1902(pdxB)
DYSG7050_06360(pdxB)
PPNPalpr_0565
PDIBDI_2825
PARCCI960_20370
PMERINE87_02476(pdxB)
PGOLK6V26_21380(pdxB)
PJOLK449_17315(pdxB)
TFOBFO_0444(pdxB)
TOHBCB71_07115
PARYA4V02_11055
DUNFDZ78_04825
BVSBARVI_06965
COPRCop2CBH44_24100(pdxB)
ALQC7Y71_005225(pdxB)
AFDAlfi_2026
ASHAL1_21410
ALDGFH31_04015
AOKA3BBH6_07070(pdxB)
ACOUA5CBH24_07680(pdxB)
ADAA5CPEGH6_08170(pdxB)
AITAI2BBH_02610(pdxB)
RBCBN938_2257
TTZFHG85_08450
BACCBRDCF_p1202(pdxB)
DORIFH5T_18275
DRCG0Q07_10480(pdxB)
MCOSGM418_31305(pdxB)
ASXCDL62_07220
ALKQM9189_00900
SRUSRU_2082(pdxB)
SRMSRM_02299(pdxB)
RMRRmar_0250
RMGRhom172_0233
RBARAWN76_010270
IALIALB_2961(pdxB)
MROMROS_1561
CPRVCYPRO_1662
 » show all
Reference
1  [PMID:2121717]
  Authors
Lam HM, Winkler ME.
  Title
Metabolic relationships between pyridoxine (vitamin B6) and serine biosynthesis in Escherichia coli K-12.
  Journal
J Bacteriol 172:6518-28 (1990)
DOI:10.1128/JB.172.11.6518-6528.1990
Reference
2  [PMID:11844765]
  Authors
Pease AJ, Roa BR, Luo W, Winkler ME
  Title
Positive growth rate-dependent regulation of the pdxA, ksgA, and pdxB genes of Escherichia coli K-12.
  Journal
J Bacteriol 184:1359-69 (2002)
DOI:10.1128/JB.184.5.1359-1369.2002
  Sequence
[eco:b2320]
Reference
3  [PMID:8550422]
  Authors
Zhao G, Winkler ME
  Title
A novel alpha-ketoglutarate reductase activity of the serA-encoded 3-phosphoglycerate dehydrogenase of Escherichia coli K-12 and its possible implications for human 2-hydroxyglutaric aciduria.
  Journal
J Bacteriol 178:232-9 (1996)
DOI:10.1128/JB.178.1.232-239.1996
Reference
4  [PMID:2692566]
  Authors
Grant GA.
  Title
A new family of 2-hydroxyacid dehydrogenases.
  Journal
Biochem Biophys Res Commun 165:1371-4 (1989)
DOI:10.1016/0006-291X(89)92755-1
Reference
5  [PMID:2681152]
  Authors
Schoenlein PV, Roa BB, Winkler ME
  Title
Divergent transcription of pdxB and homology between the pdxB and serA gene products in Escherichia coli K-12.
  Journal
J Bacteriol 171:6084-92 (1989)
DOI:10.1128/JB.171.11.6084-6092.1989
  Sequence
[eco:b2320]
Reference
6  [PMID:20831184]
  Authors
Rudolph J, Kim J, Copley SD
  Title
Multiple turnovers of the nicotino-enzyme PdxB require alpha-keto acids as cosubstrates.
  Journal
Biochemistry 49:9249-55 (2010)
DOI:10.1021/bi101291d
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.290
IUBMB Enzyme Nomenclature: 1.1.1.290
ExPASy - ENZYME nomenclature database: 1.1.1.290
BRENDA, the Enzyme Database: 1.1.1.290
CAS: 125858-75-5

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