KEGG   ENZYME: 1.1.1.366
Entry
EC 1.1.1.366                Enzyme                                 
Name
L-idonate 5-dehydrogenase (NAD+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-idonate:NAD+ oxidoreductase
Reaction(IUBMB)
L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+ [RN:R05683]
Reaction(KEGG)
R05683
Substrate
L-idonate [CPD:C00770];
NAD+ [CPD:C00003]
Product
5-dehydro-D-gluconate [CPD:C01062];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the catabolism of ascorbate (vitamin C) to tartrate. No activity is observed with NADP+ (cf. EC 1.1.1.264, L-idonate 5-dehydrogenase).
History
EC 1.1.1.366 created 2013
Orthology
K19635  L-idonate 5-dehydrogenase
Genes
DGR: 6567995
PVUL: 126811374
VVI: 100232980 100257330
VRI: 117933500 117933501
Reference
1  [PMID:16567629]
  Authors
DeBolt S, Cook DR, Ford CM
  Title
L-tartaric acid synthesis from vitamin C in higher plants.
  Journal
Proc Natl Acad Sci U S A 103:5608-13 (2006)
DOI:10.1073/pnas.0510864103
  Sequence
[vvi:100232980 100257330]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.366
IUBMB Enzyme Nomenclature: 1.1.1.366
ExPASy - ENZYME nomenclature database: 1.1.1.366
BRENDA, the Enzyme Database: 1.1.1.366

  All links  
Chemical substance (5)   
   KEGG COMPOUND (5)   
Chemical reaction (2)   
   KEGG REACTION (1)   
   KEGG RCLASS (1)   
Gene (7)   
   KEGG ORTHOLOGY (1)   
   KEGG GENES (6)   
Protein sequence (4)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (1)   
DNA sequence (2)   
   RefSeq(nuc) (1)   
   EMBL (1)   
Protein domain (7)   
   InterPro (7)   
All databases (27)   

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