KEGG   ENZYME: 1.1.1.366
Entry
EC 1.1.1.366                Enzyme                                 
Name
L-idonate 5-dehydrogenase (NAD+)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With NAD+ or NADP+ as acceptor
Sysname
L-idonate:NAD+ oxidoreductase
Reaction(IUBMB)
L-idonate + NAD+ = 5-dehydro-D-gluconate + NADH + H+ [RN:R05683]
Reaction(KEGG)
R05683
Substrate
L-idonate [CPD:C00770];
NAD+ [CPD:C00003]
Product
5-dehydro-D-gluconate [CPD:C01062];
NADH [CPD:C00004];
H+ [CPD:C00080]
Comment
Involved in the catabolism of ascorbate (vitamin C) to tartrate. No activity is observed with NADP+ (cf. EC 1.1.1.264, L-idonate 5-dehydrogenase).
History
EC 1.1.1.366 created 2013
Orthology
K19635  L-idonate 5-dehydrogenase
Genes
DGR: 6567995
PVUL: 126811374
VVI: 100232980 100257330
VRI: 117933500 117933501
Reference
1  [PMID:16567629]
  Authors
DeBolt S, Cook DR, Ford CM
  Title
L-tartaric acid synthesis from vitamin C in higher plants.
  Journal
Proc Natl Acad Sci U S A 103:5608-13 (2006)
DOI:10.1073/pnas.0510864103
  Sequence
[vvi:100232980 100257330]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.1.366
IUBMB Enzyme Nomenclature: 1.1.1.366
ExPASy - ENZYME nomenclature database: 1.1.1.366
BRENDA, the Enzyme Database: 1.1.1.366

  All links  
Protein sequence (5)   
   UniProt (2)   
   SWISS-PROT (1)   
   RefSeq(pep) (2)   
DNA sequence (4)   
   RefSeq(nuc) (2)   
   GenBank (1)   
   EMBL (1)   
All databases (9)   

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