KEGG   ENZYME: 1.1.3.48
Entry
EC 1.1.3.48                 Enzyme                                 

Name
3-deoxy-alpha-D-manno-octulosonate 8-oxidase;
kdnB (gene name)
Class
Oxidoreductases;
Acting on the CH-OH group of donors;
With oxygen as acceptor
Sysname
3-deoxy-alpha-D-manno-octulopyranosonate:oxygen 8-oxidoreductase
Reaction(IUBMB)
3-deoxy-alpha-D-manno-octulopyranosonate + O2 = 3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate + H2O2
Reaction(KEGG)
(other) R11394
Substrate
3-deoxy-alpha-D-manno-octulopyranosonate;
O2 [CPD:C00007]
Product
3,8-dideoxy-8-oxo-alpha-D-manno-octulosonate;
H2O2 [CPD:C00027]
Comment
The enzyme, characterized from the bacterium Shewanella oneidensis, is involved in the formation of 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate, an aminated form of Kdo found in lipopolysaccharides of members of the Shewanella genus. cf. EC 2.6.1.109, 8-amino-3,8-dideoxy-alpha-D-manno-octulosonate transaminase.
History
EC 1.1.3.48 created 2015
Orthology
K19714  3-deoxy-alpha-D-manno-octulosonate 8-oxidase
Genes
SON: SO_2477
SDN: Sden_2133
SFR: Sfri_1760
SAZ: Sama_1640
SBL: Sbal_2374
SBM: Shew185_2362
SBN: Sbal195_2477
SBP: Sbal223_1985
SBT: Sbal678_2479
SBS: Sbal117_2506
SLO: Shew_1857
SSE: Ssed_2423
SHL: Shal_2315
SWD: Swoo_2183
SWP: swp_2703
SVO: SVI_1928
SPSW: Sps_00648
SBK: SHEWBE_2917(kdnB)
SKH: STH12_01315(mdh_2)
SCAA: TUM17387_18770(kdnB)
TCX: Tcr_2140
HMAR: HVMH_2252(kdnB)
TZO: THMIRHAT_01670(kdnB)
CHYO: CHH_0022
DVU: DVU_0353
DVL: Dvul_2631
DVM: DvMF_1890
DDS: Ddes_2213
DTR: RSDT_0947
DPS: DP2466
DBK: DGMP_07680(kdnB)
DOL: Dole_3202
DAL: Dalk_0882
DTO: TOL2_C12560(adh)
DOV: DSCO28_27060(kdnB)
DWD: DSCW_63350(kdnB)
DALK: DSCA_59380(kdnB)
DLI: dnl_17460(adh2)
DMM: dnm_075570(Adh)
SAT: SYN_00021
MAGN: WV31_13170
LIL: LA_1616
LIE: LIF_A1303
LIC: LIC_12166
LBJ: LBJ_1112
LBL: LBL_1166
CPI: Cpin_0804
FLN: FLA_5817
SLI: Slin_2803
FLM: MY04_1601
MARM: YQ22_02485
CBAL: M667_11505
CBAT: M666_11560
MLT: VC82_293
AEV: EI546_04545(kdsB)
WIN: WPG_2941
AALG: AREALGSMS7_02862(kdnB)
AUE: C5O00_12215(kdsB)
SPON: HME9304_02711(yiaY)
KOS: KORDIASMS9_02639(kdnB)
KAN: IMCC3317_44420(kdnB)
MARF: CJ739_3530
AQB: D1818_00075(kdsB)
AQA: D1815_07205(kdsB)
AQD: D1816_06605(kdsB)
MGEL: G5B37_02710(kdsB)
MESQ: C7H62_2333
MARX: INR76_11225(kdsB)
FBU: UJ101_00783(yiaY)
 » show all
Reference
1  [PMID:23413030]
  Authors
Gattis SG, Chung HS, Trent MS, Raetz CR
  Title
The origin of 8-amino-3,8-dideoxy-D-manno-octulosonic acid (Kdo8N) in the lipopolysaccharide of Shewanella oneidensis.
  Journal
J Biol Chem 288:9216-25 (2013)
DOI:10.1074/jbc.M113.453324
  Sequence
[son:SO_2477]
Other DBs
ExplorEnz - The Enzyme Database: 1.1.3.48
IUBMB Enzyme Nomenclature: 1.1.3.48
ExPASy - ENZYME nomenclature database: 1.1.3.48
BRENDA, the Enzyme Database: 1.1.3.48

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