KEGG   ENZYME: 1.14.19.76
Entry
EC 1.14.19.76               Enzyme                                 

Name
flavone synthase II;
CYP93B16 (gene name);
CYP93G1 (gene name);
FNS II
Class
Oxidoreductases;
Acting on paired donors, with incorporation or reduction of molecular oxygen;
With oxidation of a pair of donors resulting in the reduction of O2 to two molecules of water
Sysname
flavanone,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (flavone-forming)
Reaction(IUBMB)
a flavanone + [reduced NADPH---hemoprotein reductase] + O2 = a flavone + [oxidized NADPH---hemoprotein reductase] + 2 H2O [RN:R12276]
Reaction(KEGG)
Substrate
flavanone [CPD:C00766];
[reduced NADPH---hemoprotein reductase] [CPD:C03024];
O2 [CPD:C00007]
Product
flavone [CPD:C10043];
[oxidized NADPH---hemoprotein reductase] [CPD:C03161];
H2O [CPD:C00001]
Comment
A cytochrome P-450 (heme-thiolate) protein found in plants. The rice enzyme channels flavanones to the biosynthesis of tricin O-linked conjugates. cf. EC 1.14.20.5, flavone synthase I.
History
EC 1.14.19.76 created 2018
Pathway
ec00941  Flavonoid biosynthesis
ec00943  Isoflavonoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K23179  flavone synthase II
K23180  flavone synthase II
Genes
CIT: 102609972 102611200
CIC: CICLE_v10019810mg CICLE_v10019811mg
TCC: 18593008 18593084
GRA: 105781200
GHI: 107919519
GAB: 108462515 108463531
DZI: 111315053
EGR: 104432774 104432776
GMX: 100783503(FNSII-1) 100784036(FNSII-2)
GSJ: 114379343 114379736
VUN: 114169631
CAM: 101511254
ADU: 107477091
AIP: 107634112
PMUM: 103323926
PXB: 103949014
ZJU: 107404431
JCU: 105628352
PEU: 105124985
SIND: 105170377
OEU: 111402974
HAN: 110873193
LSV: 111905568
CCAV: 112518085
OSA: 4334886
DOSA: Os04t0101400-01(Os04g0101400)
BDI: 100841298
ATS: 109733276(LOC109733276)
SBI: 8056944
ZMA: 103641445
SITA: 101761949
 » show all
Reference
1  [PMID:10652133]
  Authors
Martens S, Forkmann G
  Title
Cloning and expression of flavone synthase II from Gerbera hybrids.
  Journal
Plant J 20:611-8 (1999)
DOI:10.1046/j.1365-313X.1999.00636.x
  Sequence
Reference
2  [PMID:20132953]
  Authors
Fliegmann J, Furtwangler K, Malterer G, Cantarello C, Schuler G, Ebel J, Mithofer A
  Title
Flavone synthase II (CYP93B16) from soybean (Glycine max L.).
  Journal
Phytochemistry 71:508-14 (2010)
DOI:10.1016/j.phytochem.2010.01.007
  Sequence
[gmx:100783503]
Reference
3  [PMID:24843076]
  Authors
Lam PY, Zhu FY, Chan WL, Liu H, Lo C
  Title
Cytochrome P450 93G1 Is a Flavone Synthase II That Channels Flavanones to the Biosynthesis of Tricin O-Linked Conjugates in Rice.
  Journal
Plant Physiol 165:1315-1327 (2014)
DOI:10.1104/pp.114.239723
  Sequence
[osa:4334886]
Other DBs
ExplorEnz - The Enzyme Database: 1.14.19.76
IUBMB Enzyme Nomenclature: 1.14.19.76
ExPASy - ENZYME nomenclature database: 1.14.19.76
BRENDA, the Enzyme Database: 1.14.19.76

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