phzM (gene name)
Transferring one-carbon groups;
S-adenosyl-L-methionine + phenazine-1-carboxylate = S-adenosyl-L-homocysteine + 5-methylphenazine-1-carboxylate [RN:
The enzyme, characterized from the bacterium Pseudomonas aeruginosa, is involved in the biosynthesis of pyocyanin, a toxin produced and secreted by the organism. The enzyme is active in vitro only in the presence of EC
, 5-methylphenazine-1-carboxylate 1-monooxygenase.
EC 18.104.22.1687 created 2016
ec01110 Biosynthesis of secondary metabolites
K21103 phenazine-1-carboxylate N-methyltransferase
PAEB: NCGM1900_0750(phzM) » show all
Parsons JF, Greenhagen BT, Shi K, Calabrese K, Robinson H, Ladner JE
Structural and functional analysis of the pyocyanin biosynthetic protein PhzM from Pseudomonas aeruginosa.
ExPASy - ENZYME nomenclature database: 22.214.171.1247