Entry
Name
flavone 3'-O-methyltransferase;
o-dihydric phenol methyltransferase;
luteolin methyltransferase;
luteolin 3'-O-methyltransferase;
o-diphenol m-O-methyltransferase;
o-dihydric phenol meta-O-methyltransferase;
S-adenosylmethionine:flavone/flavonol 3'-O-methyltransferase;
quercetin 3'-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3'-hydroxyflavone 3'-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3'-hydroxyflavone = S-adenosyl-L-homocysteine + 3'-methoxyflavone [RN:
R10824 ]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:
C00019 ];
3'-hydroxyflavone [CPD:
C20871 ]
Product
S-adenosyl-L-homocysteine [CPD:
C00021 ];
3'-methoxyflavone [CPD:
C20872 ]
Comment
The enzyme prefers flavones with vicinal 3',4'-dihydroxyl groups.
History
EC 2.1.1.42 created 1976, modified 2011
Pathway
ec00944 Flavone and flavonol biosynthesis
Reference
Authors
Ebel J, Hahlbrock K, Grisebach H.
Title
Purification and properties of an o-dihydricphenol meta-O-methyltransferase from cell suspension cultures of parsley and its relation to flavonoid biosynthesis.
Journal
Reference
Authors
Muzac I, Wang J, Anzellotti D, Zhang H, Ibrahim RK
Title
Functional expression of an Arabidopsis cDNA clone encoding a flavonol 3'-O-methyltransferase and characterization of the gene product.
Journal
Sequence
Reference
Authors
Poulton JE, Hahlbrock K, Grisebach H
Title
O-Methylation of flavonoid substrates by a partially purified enzyme from soybean cell suspension cultures.
Journal
Reference
Authors
Kim BG, Lee HJ, Park Y, Lim Y, Ahn JH
Title
Characterization of an O-methyltransferase from soybean.
Journal
Reference
Authors
Lee YJ, Kim BG, Chong Y, Lim Y, Ahn JH
Title
Cation dependent O-methyltransferases from rice.
Journal
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.42
ExPASy - ENZYME nomenclature database: 2.1.1.42