KEGG   ENZYME: 2.1.1.68Help
Entry
EC 2.1.1.68                 Enzyme                                 

Name
caffeate O-methyltransferase;
caffeate methyltransferase;
caffeate 3-O-methyltransferase;
S-adenosyl-L-methionine:caffeic acid-O-methyltransferase
Class
Transferases;
Transferring one-carbon groups;
Methyltransferases
BRITE hierarchy
Sysname
S-adenosyl-L-methionine:3,4-dihydroxy-trans-cinnamate 3-O-methyltransferase
Reaction(IUBMB)
S-adenosyl-L-methionine + 3,4-dihydroxy-trans-cinnamate = S-adenosyl-L-homocysteine + 3-methoxy-4-hydroxy-trans-cinnamate [RN:R03366]
Reaction(KEGG)
Substrate
S-adenosyl-L-methionine [CPD:C00019];
3,4-dihydroxy-trans-cinnamate [CPD:C01197]
Product
S-adenosyl-L-homocysteine [CPD:C00021];
3-methoxy-4-hydroxy-trans-cinnamate [CPD:C01494]
Comment
3,4-Dihydroxybenzaldehyde and catechol can act as acceptors, but more slowly.
History
EC 2.1.1.68 created 1984
Pathway
ec00940  Phenylpropanoid biosynthesis
ec01100  Metabolic pathways
ec01110  Biosynthesis of secondary metabolites
Orthology
K13066  caffeic acid 3-O-methyltransferase
Genes
RSS: 109441731 109441840
ATH: AT5G54160(OMT1)
ALY: ARALYDRAFT_313855 ARALYDRAFT_314426 ARALYDRAFT_353659 ARALYDRAFT_354029 ARALYDRAFT_475033 ARALYDRAFT_476917 ARALYDRAFT_476918 ARALYDRAFT_495497(ATOMT1) ARALYDRAFT_675184 ARALYDRAFT_684972 ARALYDRAFT_892191 ARALYDRAFT_893153 ARALYDRAFT_913747 ARALYDRAFT_913762 ARALYDRAFT_918528(ATOMT1)
CRB: 17876399 17876808 17880712 17887517 17892266 17894852 17895006 17895150 17896262 17896602 17896611 17900372
CSAT: 104700852 104702535 104702536 104703789 104703933 104703934 104713420 104713422 104714664 104714665 104714666 104714667 104717023 104717445 104719521 104721668 104721671 104722135 104724216 104725900 104725937 104728864 104729294 104730122 104730586 104730602 104741895 104741993 104751650 104752845 104752980 104752981 104753499 104757436 104757680 104761441 109129651 109130500
EUS: EUTSA_v10008040mg EUTSA_v10013896mg EUTSA_v10013897mg EUTSA_v10013908mg EUTSA_v10014001mg EUTSA_v10015575mg EUTSA_v10018703mg EUTSA_v10023537mg EUTSA_v10025490mg EUTSA_v10025520mg EUTSA_v10025522mg EUTSA_v10027501mg
BRP: 103827916 103830562 103830566 103832198 103833645 103833646 103834597 103838067 103844876(OMT1-BR-3) 103844878 103851608 103851985 103853080 103853081 103857055(OMT1-BR-1) 103861716 103868698 103870469
BNA: 106353479 106353480 106356003 106356577 106356601 106356929 106357154 106357352 106364265 106364267 106369877 106373040 106373206 106374490 106375404 106379181 106379182 106383908 106383909 106383910 106383914 106383915 106384547 106385406 106385989 106385991 106385992 106386608 106392944 106393599 106394726 106403425 106409029 106409594 106417606 106418605 106418764 106418880 106423995 106424169 106427507 106427553 106432400 106434499 106434512 106435293 106437132 106437143 106437536 106444684 106444972 106449042 106454902 111198198 111200910 111205367 111206996 111211952
BOE: 106296210 106296887 106298971 106299322 106299497 106301934 106301936 106304347 106309932 106311050 106314910 106314911 106315790 106317199 106318898 106318901 106320085 106321835 106321886 106322876 106324620 106324621 106326817 106331136 106332463 106333186 106333198 106336119 106340825
THJ: 104799941 104799942 104799943 104800201 104800202 104802099 104804741 104805817 104810205 104811887 104813066 104813660 104813661 104813662 104813663 104813820 104814017 104814749 104816236
CPAP: 110823164
LJA: Lj0g3v0034909.1(Lj0g3v0034909.1) Lj0g3v0105429.1(Lj0g3v0105429.1) Lj0g3v0124669.1(Lj0g3v0124669.1) Lj0g3v0273599.1(Lj0g3v0273599.1) Lj0g3v0306659.1(Lj0g3v0306659.1) Lj0g3v0346019.1(Lj0g3v0346019.1) Lj0g3v0354359.1(Lj0g3v0354359.1) Lj0g3v0364049.1(Lj0g3v0364049.1) Lj1g3v1079700.1(Lj1g3v1079700.1) Lj1g3v5060810.1(Lj1g3v5060810.1) Lj1g3v5060810.2(Lj1g3v5060810.2) Lj2g3v3339490.1(Lj2g3v3339490.1)
DOSA: Os04t0175600-01(Os04g0175600) Os12t0199500-00(Os12g0199500) Os12t0202700-00(Os12g0202700)
PDA: 103716997
EGU: 105042923
ATR: 18424568
 » show all
Taxonomy
Reference
1  [PMID:4472044]
  Authors
Ebel J, Schaller-Hekeler B, Knobloch KH, Wellman E, Grisebach H, Hahlbrock K.
  Title
Coordinated changes in enzyme activities of phenylpropanoid metabolism during the growth of soybean cell suspension cultures.
  Journal
Biochim Biophys Acta 362:417-24 (1974)
DOI:10.1016/0304-4165(74)90137-8
Reference
2  [PMID:241400]
  Authors
Poulton JE, Butt VS.
  Title
Purification and properties of S-adenosyl-L-methionine: caffeic acid O-methyltransferase from leaves of spinach beet (Beta vulgaris L).
  Journal
Biochim Biophys Acta 403:301-14 (1975)
DOI:10.1016/0005-2744(75)90060-1
Reference
3
  Authors
Shimada, M., Kuroda, H. and Higuchi, T.
  Title
Evidence for the formation of methoxyl groups of ferulic and sinapic acid in Bambusa by the same O-methyltransferase.
  Journal
Phytochemistry 12:2873-2875 (1973)
Other DBs
ExplorEnz - The Enzyme Database: 2.1.1.68
IUBMB Enzyme Nomenclature: 2.1.1.68
ExPASy - ENZYME nomenclature database: 2.1.1.68
BRENDA, the Enzyme Database: 2.1.1.68
CAS: 50936-45-3

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