KEGG   ENZYME: 2.3.1.210
Entry
EC 2.3.1.210                Enzyme                                 
Name
dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase;
TDP-fucosamine acetyltransferase;
WecD;
RffC
Class
Transferases;
Acyltransferases;
Transferring groups other than aminoacyl groups
Sysname
acetyl-CoA:dTDP-4-amino-4,6-dideoxy-alpha-D-galactose N-acetyltransferase
Reaction(IUBMB)
acetyl-CoA + dTDP-4-amino-4,6-dideoxy-alpha-D-galactose = CoA + dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose [RN:R10142]
Reaction(KEGG)
R10142
Substrate
acetyl-CoA [CPD:C00024];
dTDP-4-amino-4,6-dideoxy-alpha-D-galactose [CPD:C04346]
Product
CoA [CPD:C00010];
dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose [CPD:C20415]
Comment
The product, TDP-4-acetamido-4,6-dideoxy-D-galactose, is utilized in the biosynthesis of enterobacterial common antigen (ECA).
History
EC 2.3.1.210 created 2012
Pathway
ec00541  O-Antigen nucleotide sugar biosynthesis
ec01100  Metabolic pathways
Orthology
K16704  dTDP-4-amino-4,6-dideoxy-D-galactose acyltransferase
Genes
ECOb3790(rffC)
ECJJW5597(rffC)
ECDECDH10B_3979(rffC)
EBWBWG_3472(rffC)
ECOKECMDS42_3228(rffC)
ECEZ5301(wecD)
ECSECs_4723(wecD)
ECFECH74115_5223(wecD)
ETWECSP_4838(rffC)
ELXCDCO157_4460
EOIECO111_4616(rffC)
EOJECO26_4796(rffC)
EOHECO103_4374(rffC)
ECOOECRM13514_4850(rffC)
ECOHECRM13516_4635(rffC)
ESLO3K_24915
ESOO3O_00425
ESMO3M_24835
ECKEC55989_4262(rffC)
ECGE2348C_4091(rffC)
EOKG2583_4584(rffC)
ELRECO55CA74_21995
ELHETEC_4072
ECWEcE24377A_4301(wecD)
EUNUMNK88_4599(wecD)
ECPECP_3981
ENAECNA114_3928(rffC)
ECOSEC958_4252(rffC)
ECVAPECO1_2685(rffC)
ECOAAPECO78_22795
ECXEcHS_A4007(wecD)
ECMEcSMS35_4154(wecD)
ECYECSE_4073
ECRECIAI1_3977(rffC)
ECQECED1_4475(rffC)
EUMECUMN_4315(rffC)
ECTECIAI39_2997(rffC)
EOCCE10_4433(rffC)
EBRECB_03668(wecD)
EBLECD_03668(wecD)
EBEB21_03617(rffC)
EBDECBD_4249
ECIUTI89_C4346(rffC)
EIHECOK1_4236(wecD)
ECZECS88_4212(rffC)
ECCc4710(wecD)
ELOEC042_4167(rffC)
ELNNRG857_18825
ESEECSF_3630
ECLEcolC_4213
EKOEKO11_4566
EKFKO11_03960(rffC)
EABECABU_c42690(rffC)
EDHEcDH1_4186
EDJECDH1ME8569_3672(rffC)
ELUUM146_19090
ELWECW_m4088(rffC)
ELLWFL_19960(rffC)
ELCi14_4303(wecD)
ELDi02_4303(wecD)
ELPP12B_c3919(rffC)
ELFLF82_1857(rffC)
ECOLLY180_19625
ECOIECOPMV1_04123
ECOJP423_20975
EFEEFER_3714(rffC)
EALEAKF1_ch2147c(wecD)
EMAC1192_16615
ESZFEM44_09735(rffC)
STYSTY3631(rffC)
STTt3373(rffC)
SEXSTBHUCCB_35570
SENTTY21A_17070
STMSTM3924(wecD)
SEOSTM14_4722(wecD)
SEVSTMMW_38991
SEYSL1344_3883(rffC)
SEMSTMDT12_C40780
SEJSTMUK_3910(wecD)
SEBSTM474_4102(wecD)
SEFUMN798_4261(rffC)
SETUSTU288_19805
SETCCFSAN001921_20810
SENRSTMDT2_37951(rffC)
SENDDT104_39421(rffC)
SENICY43_20545
SEENSE451236_01280
SPTSPA3764(rffC)
SEKSSPA3508
SPQSPAB_04869
SEISPC_4038(wecD)
SECSCH_3829(wecD)
SEHSeHA_C4253(wecD)
SHBSU5_040
SENHCFSAN002069_12420
SEEHSEEH1578_05735
SEESNSL254_A4204(wecD)
SENNSN31241_47980
SEWSeSA_A4135(wecD)
SEASeAg_B4150(wecD)
SENSQ786_19230
SEDSeD_A4312(wecD)
SEGSG3519(wecD)
SELSPUL_3502(wecD)
SEGASPUCDC_3488(wecD)
SETSEN3729(wecD)
SENAAU38_19245
SENOAU37_19240
SENVAU39_19260
SENQAU40_21465
SENLIY59_19715
SENJCFSAN001992_14040
SEECCFSAN002050_02505
SEEBSEEB0189_022715
SEEPI137_16790
SENBBN855_40020(wecD)
SENEIA1_19075
SENCSEET0819_03475
SESSARI_03729
SBGSBG_3467(rffC)
SBZA464_3984
SBVN643_17330
SALZEOS98_22715
SFLSF3864(wecD)
SFXS3896(wecD)
SFVSFV_3714(wecD)
SFESFxv_4210(rffC)
SFNSFy_5517
SFSSFyv_5582
SFTNCTC1_04176(rffC)
SSNSSON_3962(wecD)
SBOSBO_3801(wecD)
SBCSbBS512_E4131(wecD)
SDYSDY_3958(wecD)
SDZAsd1617_05187
SHQA0259_00405
ENCECL_04997
ENLA3UG_22200
ECLGEC036_43030
ECLEECNIH2_01465
ECLNECNIH4_21960
ECLIECNIH5_01005
ECLXLI66_00845
ECLYLI62_01260
ECLZLI64_00920
EHMAB284_01255
EXFBFV63_00830
ECLAECNIH3_01010
ECLCECR091_01010
EAUDI57_19305
EKBBFV64_22700
ENOECENHK_21405
EECEcWSU1_04383(rffC)
ELGBH714_23050
ECANCWI88_21950
ERNBFV67_21340
ECLSLI67_023540
ECHGFY206_23660(rffC)
ESHC1N69_22215
ENTEnt638_3998
EASEntas_4281
ENRH650_16095
ENXNI40_021435
ENFAKI40_4801
LNICWR52_13425
EBGFAI37_07580(rffC)
ENDA4308_06335
ENZG0034_22315(rffC)
ENSHWQ15_09170(rffC)
ENKLOC22_11675(rffC)
EHUD5067_0000820(rffC)
EMORL6Y89_00665(rffC)
ESAESA_03770
CSKES15_3695
CSZCSSP291_17450
CSJCSK29544_00728
CCONAFK62_01300
CDMAFK67_01270
CSIP262_05492
CMJAFK66_018830
CUIAFK65_00940
CMWAFK63_17350
CTUCTU_02260(rffC)
KPNKPN_04290(wecD)
KPUKP1_0152(wecD)
KPMKPHS_01370
KPPA79E_4898
KPHKPNIH24_00735
KPZKPNIH27_00750
KPVKPNIH29_00705
KPWKPNIH30_00740
KPYKPNIH31_00740
KPGKPNIH32_00745
KPCKPNIH10_00730
KPQKPR0928_00735
KPTVK055_3185(wecD)
KPOKPN2242_24465
KPRKPR_0244(rffC)
KPJN559_4995
KPID364_21855
KPAKPNJ1_05303
KPSKPNJ2_05259
KPXPMK1_01777(wecD)
KPBFH42_17810
KPNEKU54_025900
KPNULI86_25830
KPNKBN49_4569(rffC)
KVAKvar_4938
KPEKPK_5389(wecD)
KPKA593_11555
KVDKR75_08980
KVQSP68_15575
KOXKOX_07575
KOEA225_0158
KOYJ415_02175
KOMHR38_06160
KMIVW41_17945
KOKKONIH1_01025
KOCAB185_06195
KQUAVR78_05290
EAEEAE_07815
EARCCG32436
KQVB8P98_26835
KLLBJF97_00875
KLWDA718_28400(rffC)
KARLGL98_24215(rffC)
KGRJJJ10_26720(rffC)
RORRORB6_17920
RONTE10_03050
RPLNB1209_26095
RAODSD31_24930
RTGNCTC13098_07037
REEelectrica_04899(wecD)
CROROD_39571(rffC)
CKOCKO_00131
CFDCFNIH1_03895
CBRAA6J81_16835
CWECO701_21790
CYOCD187_23780
CPOTFOB25_11040(rffC)
CFQC2U38_25620
CSEDJY391_22100(rffC)
CAMAF384_20580
CAFAL524_03435
CIFAL515_01620
CFARCI104_24895
CIRC2U53_10160
CIEAN232_04060
CPARCUC49_19555
CTELGBC03_04800(rffC)
CITZE4Z61_16740(rffC)
CARSE1B03_01335(rffC)
EBTEBL_c37950(rffC)
CNTJT31_11680
CEMLH23_06030
CENLH86_05965
CLAPNCTC11466_04438
PGELG71_04935
ESCEntcl_4241
KLEAO703_00665
KSAC813_14575
KORAWR26_24235(rffC)
KRDA3780_25540
KCOBWI95_22870
KOTEH164_21535
KPSEIP581_00755(rffC)
KGOCEW81_23945
KIENCTC12125_03607
KASKATP_43510(rffC)
LAXAPT61_00870
LEIC2U54_03840
LEHC3F35_12655
LEEDVA44_22825
LERGNG29_22160(rffC)
LEAGNG26_21365(rffC)
LPNUKQ929_00170(rffC)
LAZA8A57_20815
LEFLJPFL01_4116
LEWDAI21_05240
BUFD8682_14690
BAGEBADSM9389_40070
BFTMNO13_23505(rffC)
SYMK6K13_22235(rffC)
METYMRY16398_54530(wecD)
AHNNCTC12129_04764
ASUBNLZ15_21315(rffC)
YREHEC60_18700(rffC)
SGOEA8O29_021775(rffC)
KINAB182_24235
PDZHHA33_01240(rffC)
IZHFEM41_06590(rffC)
PSHISAMEA2665130_3009
PSGCG163CM_34210(wecD)
EBFD782_4363
EBCC2U52_07195
EBUCUC76_14660
PSTSE05_20710 E05_20720
YPEYPO3860(b3790)
YPKy0368(wecD)
YPHYPC_0362(rffC)
YPAYPA_0158
YPNYPN_0103
YPMYP_3185(rffC)
YPPYPDSF_3478
YPGYpAngola_A0518(wecD)
YPZYPZ3_3414(wecD)
YPTA1122_06510
YPDYPD4_3406(wecD)
YPXYPD8_3406(wecD)
YPWCH59_1803(wecD)
YPJCH55_3150(wecD)
YPVBZ15_3848(wecD)
YPLCH46_1201(wecD)
YPSYPTB0174(rffC)
YPOBZ17_2415(wecD)
YPIYpsIP31758_0188(wecD)
YPYYPK_4027
YPBYPTS_0186
YPQDJ40_2250(wecD)
YPUBZ21_3525(wecD)
YPRBZ20_1951(wecD)
YPCBZ23_3797(wecD)
YPFBZ19_3632(wecD)
YENYE0175(rffC)
YEPYE105_C0178
YEYY11_33731
YELLC20_05067
YEWCH47_3310(wecD)
YETCH48_1868(wecD)
YEFFORC2_3923
YEEYE5303_41191(b3790)
YSIBF17_08865
YALAT01_2296(wecD)
YFRAW19_3032(wecD)
YINCH53_1978(wecD)
YKRCH54_2756(wecD)
YROCH64_2764(wecD)
YRUBD65_1772(wecD)
YRBUGYR_09385
YAKACZ76_10090
YMADA391_21975
YHID5F51_00930
YCAF0T03_00900(rffC)
YMOHRD69_04310(rffC)
SMARSM39_4333(rffC)
SMACSMDB11_4271(rffC)
SMWSMWW4_v1c01770(rffC)
SPESpro_0167
SRRSerAS9_0129
SRLSOD_c01230(rffC)
SRYM621_00615
SPLYQ5A_000710(wecD)
SRSSerAS12_0129
SRASerAS13_0128
SMAFD781_0135
SLQM495_00655
SERFL085_05255
SERSSERRSCBI_00735
SFWWN53_09235
SFGAV650_01750
SRZAXX16_0392
SERASer39006_003830
SERQCWC46_03830
SERMCLM71_00740
SQUE4343_15455(rffC)
SFJSAMEA4384070_0130
SOFNCTC11214_01913
SSURATE40_021560
SURIJ0X03_23200(rffC)
SRHZFO014_09275(rffC)
SENPKHA73_22505(rffC)
SFOZ042_12830
RAHRahaq_4258
RACEJHW33_15675(rffC)
RAQRahaq2_4371
RAAQ7S_21645
ROXBV494_17755
RVCJ9880_06800(rffC)
GQUAWC35_10760
FSMCCS41_11830
EAMEGXP68_20365(rffC)
RBADH2866_08920(rffC)
ECAECA4205(rffC)
PATREV46_20975
PATOGZ59_42690(rffC)
PCTPC1_4005
PCCPCC21_039840
PCVBCS7_20030
PWAPecwa_4197
PPARA8F97_20495
PECW5S_4360
PWSA7983_06130
PPOABJK05_15015
PBRAB5S52_01180
PPUJE2566_20370(wecD)
PARII2D83_01240(wecD)
PAQUDMB82_0019225(wecD)
PVZOA04_42740(rffC)
PPAVLOZ86_02275(wecD)
PQUIG609_018955(wecD)
DDDDda3937_00272(rffC)
DZEDd1591_0162
DDCDd586_3895
DZCW909_18980
DSOA4U42_07615
CEDLH89_13870
DFNCVE23_21000
DDQDDI_4002
DAQDAQ1742_04241(rffC)
DICDpoa569_000259(rffC)
DDADd703_0207
BGJAWC36_20045
BRBEH207_16150
BNGEH206_01315
BIZHC231_01300(rffC)
LBQCKQ53_04175
LPOPI6N93_00930(rffC)
SGLSG2379
SODSant_0295(rffc)
PESSOPEG_0377(rffC)
SLIGGTU79_01530(rffC)
EAMEAMY_0177(wecD)
EAYEAM_0170(rffC)
ETAETA_02030(wecD)
EPYEpC_01910(wecD)
EPREPYR_00200(wecD)
EBIEbC_02000(wecD)
ERJEJP617_13890(wecD)
EGEEM595_3330(wecD)
EPECI789_17730
ERWIGN242_20175(rffC)
ETPLU633_24960(rffC)
PAMPANA_0153(rffC)
PLFPANA5342_4274(wecD)
PAJPAJ_3313(rffC)
PAQPAGR_g4125
PVAPvag_3388(wecD)
PAGGAL522_05075
PAOPat9b_0146
KLNLH22_01530
PANTPSNIH1_06300
PANPPSNIH2_16595
PAGCBEE12_07460
PSTWDSJ_22180
PALHB1H58_08545
PANSFCN45_00755(rffC)
PEYEE896_18370(rffC)
PDISD8B20_00610
PERLAC65_00405(rffC)
PGZC2E15_20340
PCDC2E16_19760
MINTC7M51_03212(wecD_2)
MTHIC7M52_03787(wecD_2)
TCIA7K98_18805
TPTYNCTC11468_03536
PLUplu4656(wecD)
PLUMA4R40_23095
PAYPAU_04136
PTTVY86_06570
PAKHB0X70_23535
PLUICE143_23575
PMRPMI3322(rffC)
PMIBBB2000_3354(rffC)
PVLAOB99_01030
PVGCRN77_03045
PHAUPH4a_08060
PROTBTA34_17835
PCOLF1325_00990(rffC)
PCIBF9282_00990(rffC)
PPEEI6G31_08385(rffC)
XBOXBJ1_4172(rffC)
XBVXBW1_4527(rffC)
XNEXNC1_0390(rffC)
XNMXNC2_0382(rffC)
XDOXDD1_0352(rffC)
XPOXPG1_3478(rffC)
XHOA9255_14200
XBUHGO23_18245(rffC)
PSIS70_11670
PSXDR96_846(wecD)
PSTABGK56_14600
PRGRB151_042140(wecD)
PALACO695_05745
PHEINCTC12003_03733
PRQCYG50_17665(rffC)
PRJNCTC6933_03747
PVCG3341_18335(rffC)
MMKMU9_249
ANSArsFIN_02190(wecD)
AEDE3U36_04175(rffC)
AETLDL57_00970(rffC)
MWIMNY66_14805(rffC)
EICNT01EI_0096
ETRETAE_0107(wecD)
ETDETAF_0080(rffC)
ETEETEE_1868(rffC)
ETCETAC_00395
EDWQY76_02320
EDLAAZ33_00405(rffC)
EHOA9798_16295
HAVAT03_01725
HPARAL518_03880
OPODSM2777_02275
LPVHYN51_09720
PFQQQ39_17705
PRAGEKN56_00950(rffC)
LRINCTC12151_03587
HDUHD_1841(wecD)
HAPHAPS_2163(wecD)
HPAZK756_07940
HPASJL26_06815
HPAKJT17_04345
GLECJD39_10765
MHTD648_23670
MHQD650_2510
MHXMHH_c03480
MHAEF382_09225
MHAMJ450_05995
MHAOJ451_07010
MHALN220_13000
MHAQWC39_01265
MHAYVK67_01270
MVRX781_2160
MVIX808_19410
MVGX874_18190
MVEX875_1780
MGRAA4G16_10675
MBOSICJ55_01370(rffC)
APLAPL_1550(wecD)
APJAPJL_1578(rffC)
APAAPP7_1612(wecD)
ASIASU2_09880
ASSASU1_09925
AEUACEE_09215
AIOEXH44_07095(rffC)
ALIGNCTC10568_01905(rffC)
BTOWQG_19970
BTREF542_2620
BTRHF543_3280
BTRAF544_19780
OOIA6A10_01410
FCLA4G17_03535
LYTDWG18_00385
VVYVV0304
PPRCPFLCHA0_c21920
PPROPPC_2168
SALGBS332_14625
PEAPESP_a0464
PDJD0907_14795
RVIRVIR1_03450(waaE)
FPHFphi_0077
FPTBZ13_27
FPIBF30_249
FPMLA56_224
FPXKU46_1304
FPZLA55_1314
FPJLA02_1221
FMIF0R74_04505
THISHZT40_09525
BCIBIM45_429
SKUSulku_2390
GPLM1B72_08020
PSELGM415_12390
SPHKSKP52_10515
BDZDOM22_09310
BAYRBAM_035130
BAQBACAU_3537(spsD)
BYABANAU_3694(spsD)
BAMPB938_18000
BQYMUS_4173(spsD)
BAMLBAM5036_3438(spsD)
BAMARBAU_3647(spsD)
BAMNBASU_3423(spsD)
BAMBBAPNAU_3708(spsD)
BAMTAJ82_19825
BAMYV529_37850(spsD)
BMPNG74_03687
BAOBAMF_3623(spsD)
BAZBAMTA208_19180(spsD)
BQLLL3_03934(spsD)
BXHBAXH7_03926(spsD)
BAMIKSO_001520
BAMCU471_36590
BAMFU722_18735
BSIACWD84_01590
BVMB9C48_17970
BPUBPUM_3433
BPUMBW16_18225
BPUSUP12_17670
BXIBK049_09750
BALTCFN77_18130
BSAFBSL056_18775
BACWQR42_17225
BACPSB24_11155
BACBOY17_01225
BACSAUL54_12160
GRCGI584_20450
PPEOABE82_23090
PAIHASL14_14830
PRTAUC31_14920
ERLAOC36_08660
ABAIIMCC26256_112338
ATMANT_20150
PSUBPelsub_P1085
PBFCFX0092_A3415
VBHCMV30_12575
TTFTHTE_2347
VBCC5Q97_02340
COYHF329_17535
CMRCycma_3700
CAMUCA2015_3028 CA2015_3629
MDAIPZ59_15370
CHUCHU_2998
SPIBG8759_15415
RHOZGXP67_05045
RUNDR864_23610
EOLEmtol_1313
FLIFleli_1537
HSWHsw_3422
HYMN008_03995
HYDPK28_14720
HYEAM218_01705
HNVDDQ68_20360
HYJFHG12_12535
HQIH9L05_02480
HRSHER32_06915
HBNGUY19_08870
HTSHMJ29_03160 HMJ29_11590
HMTMTP16_11905 MTP16_12050
HTBMTX78_04870
RUFTH63_02680
RTIDC20_13155
NIBGU926_17025
ADDHUW48_01610
FKAKM029_03920
FGLEM308_00580
FPALHYN49_03755
FMGHYN48_03680
MAREEJ994_13090
PCEAJ3359_17240
FORFORMB_06520
SALTAO058_10620
AQBD1818_09110
MARXINR76_00320
FBEFF125_12050
CIHATE47_15540
ARGQT11_C0001G0505
 » show all
Reference
1  [PMID:16855251]
  Authors
Hung MN, Rangarajan E, Munger C, Nadeau G, Sulea T, Matte A
  Title
Crystal structure of TDP-fucosamine acetyltransferase (WecD) from Escherichia coli, an enzyme required for enterobacterial common antigen synthesis.
  Journal
J Bacteriol 188:5606-17 (2006)
DOI:10.1128/JB.00306-06
  Sequence
[ecc:c4710]
Other DBs
ExplorEnz - The Enzyme Database: 2.3.1.210
IUBMB Enzyme Nomenclature: 2.3.1.210
ExPASy - ENZYME nomenclature database: 2.3.1.210
BRENDA, the Enzyme Database: 2.3.1.210

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