KEGG   ENZYME: 2.4.1.325
Entry
EC 2.4.1.325                Enzyme                                 
Name
TDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase;
TDP-Fuc4NAc:lipid II Fuc4NAc-transferase;
TDP-Fuc4NAc:lipid II Fuc4NAc transferase;
wecF (gene name)
Class
Transferases;
Glycosyltransferases;
Hexosyltransferases
Sysname
dTDP-N-acetyl-alpha-D-fucose:N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol N-acetylfucosaminyltransferase
Reaction(IUBMB)
dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose + N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol = dTDP + 4-acetamido-4,6-dideoxy-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol [RN:R10303]
Reaction(KEGG)
R10303
Substrate
dTDP-4-acetamido-4,6-dideoxy-alpha-D-galactose [CPD:C20415];
N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Product
dTDP [CPD:C00363];
4-acetamido-4,6-dideoxy-alpha-D-galactosyl-(1->4)-N-acetyl-beta-D-mannosaminouronyl-(1->4)-N-acetyl-alpha-D-glucosaminyl-diphospho-ditrans,octacis-undecaprenol
Comment
Involved in the enterobacterial common antigen (ECA) biosynthesis in the bacterium Escherichia coli. The trisaccharide of the product (lipid III) is the repeat unit of ECA.
History
EC 2.4.1.325 created 2014
Orthology
K12582  dTDP-N-acetylfucosamine:lipid II N-acetylfucosaminyltransferase
Genes
ECOb4481(wecF)
ECJJW5596(rffT)
ECDECDH10B_3982(rffT)
EBWBWG_3475(rffT)
ECOKECMDS42_3231(rffT)
ECEZ5304
ECSECs_4726(wecF)
ECFECH74115_5226(wecF)
ETWECSP_4841(rffT)
ELXCDCO157_4463
EOIECO111_4619(rffT)
EOJECO26_4793(rffT)
EOHECO103_4371(rffT)
ECOOECRM13514_4853
ECOHECRM13516_4638
ESLO3K_24900
ESOO3O_00440
ESMO3M_24820
ECKEC55989_4265(rffT)
ECGE2348C_4094(rffT)
EOKG2583_4587(rffT)
ELRECO55CA74_22010
ELHETEC_4075
ECWEcE24377A_4305(wecF)
EUNUMNK88_4602
ECPECP_3984
ENAECNA114_3931(rffT)
ECOSEC958_4255
ECVAPECO1_2682(rffT)
ECOAAPECO78_22810
ECXEcHS_A4010(wecF)
ECMEcSMS35_4157(wecF)
ECYECSE_4076
ECRECIAI1_3980(rffT)
ECQECED1_4478(rffT)
EUMECUMN_4318(rffT)
ECTECIAI39_2994(rffT)
EOCCE10_4436(rffT)
EBRECB_03671(rffT)
EBLECD_03671(wecF)
EBEB21_03620(rffT)
EBDECBD_4246
ECIUTI89_C4350
EIHECOK1_4239(wecF)
ECZECS88_4215(rffT)
ECCc4714
ELOEC042_4170(rffT)
ELNNRG857_18840
ESEECSF_3633
ECLEcolC_4210
EKOEKO11_4563
EKFKO11_03975(rffT)
EABECABU_c42720(rffT)
EDHEcDH1_4183
EDJECDH1ME8569_3675(rffT)
ELUUM146_19105
ELWECW_m4091(rffT)
ELLWFL_19975(rffT)
ELCi14_4307
ELDi02_4307
ELPP12B_c3923(wecF)
ELFLF82_1863(rffT)
ECOLLY180_19640
ECOIECOPMV1_04126(wecF)
ECOJP423_20990
EFEEFER_3711(rffT)
EALEAKF1_ch2144c(wecF)
EMAC1192_16600
ESZFEM44_09720(rffT)
STYSTY3628
STTt3370
SEXSTBHUCCB_35540
SENTTY21A_17055
STMSTM3927
SEOSTM14_4725
SEVSTMMW_39021
SEYSL1344_3886
SEMSTMDT12_C40810
SEJSTMUK_3913
SEBSTM474_4105
SEFUMN798_4264
SETUSTU288_19820
SETCCFSAN001921_20795
SENRSTMDT2_37981
SENDDT104_39451
SENICY43_20560
SEENSE451236_01265
SPTSPA3767
SEKSSPA3511
SPQSPAB_04872
SEISPC_4041
SECSCH_3832
SEHSeHA_C4256(wecF)
SHBSU5_043
SENHCFSAN002069_12405
SEEHSEEH1578_05750
SEESNSL254_A4207(wecF)
SENNSN31241_47950
SEWSeSA_A4138(wecF)
SEASeAg_B4153(wecF)
SENSQ786_19245
SEDSeD_A4315(wecF)
SEGSG3516
SELSPUL_3499
SEGASPUCDC_3485
SETSEN3732
SENAAU38_19260
SENOAU37_19255
SENVAU39_19275
SENQAU40_21480
SENLIY59_19730
SENJCFSAN001992_14025
SEECCFSAN002050_02520
SEEBSEEB0189_022700
SEEPI137_16775
SENBBN855_40050(wecF)
SENEIA1_19090
SENCSEET0819_03490
SESSARI_03726
SBGSBG_3470
SBZA464_3987
SBVN643_17345
SALZEOS98_22700
SFLSF3867(yifM)
SFXS3893(yifM)
SFVSFV_3711(yifM)
SFESFxv_4213(rffT)
SFNSFy_5521
SFSSFyv_5586
SFTNCTC1_04179(wecF)
SSNSSON_3965(yifM)
SBOSBO_3804(yifM)
SBCSbBS512_E4128(wecF)
SDYSDY_3955(yifM)
SDZAsd1617_05184
SHQA0259_00420
ENCECL_04994
ENLA3UG_22185
ECLGEC036_43000
ECLEECNIH2_01480
ECLNECNIH4_21945
ECLIECNIH5_01020
ECLXLI66_00860
ECLYLI62_01275
ECLZLI64_00935
ECLOENC_02110
EHMAB284_01240
EXFBFV63_00845
ECLAECNIH3_01025
ECLCECR091_01025
EAUDI57_19320
EKBBFV64_22685
ENOECENHK_21390
EECEcWSU1_04380(wecF)
ELGBH714_23065
ECANCWI88_21935
ERNBFV67_21325
ECLSLI67_023525
ECHGFY206_23645
ESHC1N69_22200
ENTEnt638_3995
EASEntas_4278
ENRH650_16110
ENXNI40_021420
ENFAKI40_4798
LNICWR52_13440
EBGFAI37_07595
ENDA4308_06320
ENZG0034_22300
ENSHWQ15_09185
ENKLOC22_11690
ESAESA_03767
CSKES15_3692(wecF)
CSZCSSP291_17435
CSJCSK29544_00725
CCONAFK62_01315
CDMAFK67_01285
CSIP262_05488
CMJAFK66_018815
CUIAFK65_00955
CMWAFK63_17335
CTUCTU_02290(wecF)
KPNKPN_04293(wecF)
KPUKP1_0155(wecF)
KPMKPHS_01400
KPPA79E_4895
KPHKPNIH24_00750
KPZKPNIH27_00765
KPVKPNIH29_00720
KPWKPNIH30_00755
KPYKPNIH31_00755
KPGKPNIH32_00760
KPCKPNIH10_00745
KPQKPR0928_00750
KPTVK055_3182(wecF)
KPOKPN2242_24480
KPRKPR_0247(wecF)
KPJN559_4992
KPID364_21870
KPAKPNJ1_05300
KPSKPNJ2_05256
KPXPMK1_01780(wecF)
KPBFH42_17825
KPNEKU54_025915
KPNULI86_25815
KPNKBN49_4566(wecF)
KVAKvar_4935
KPEKPK_5386(wecF)
KPKA593_11570
KVDKR75_08995
KVQSP68_15590
KOXKOX_07590
KOEA225_0161
KOYJ415_02160
KOMHR38_06175
KMIVW41_17930
KOKKONIH1_01040
KOCAB185_06180
KQUAVR78_05305
EAEEAE_07830
EARCCG32433
KQVB8P98_26820
KLLBJF97_00890
KLWDA718_28385
KARLGL98_24200
KGRJJJ10_26705
RORRORB6_17905
RONTE10_03065
RPLNB1209_26080
RAODSD31_24915
RTGNCTC13098_07031(wecF)
REEelectrica_04896(wecF)
CROROD_39541(rffT)
CKOCKO_00134
CFDCFNIH1_03880
CBRAA6J81_16820
CWECO701_21775
CYOCD187_23765
CPOTFOB25_11025
CFQC2U38_25605
CSEDJY391_22085
CAMAF384_20595
CAFAL524_03450
CIFAL515_01635
CFARCI104_24880
CIRC2U53_10175
CIEAN232_04045
CPARCUC49_19570
CTELGBC03_04815
CITZE4Z61_16725
CARSE1B03_01350
EBTEBL_c37920(rffT)
CNTJT31_11665
CEMLH23_06045
CENLH86_05980
CLAPNCTC11466_04435(wecF)
PGELG71_04950
ESCEntcl_4238
KLEAO703_00680
KSAC813_14560
KORAWR26_24220
KRDA3780_25555
KCOBWI95_22855
KOTEH164_21520
KPSEIP581_00770
KGOCEW81_23930
KIENCTC12125_03604(wecF)
KASKATP_43480(wecF)
LAXAPT61_00885
LEIC2U54_03825
LEHC3F35_12670
LEEDVA44_22810
LERGNG29_22145
LEAGNG26_21350
LAZA8A57_20800
LEFLJPFL01_4113
LEWDAI21_05255
BUFD8682_14675
BAGEBADSM9389_40040
SYMK6K13_22220
METYMRY16398_54500(wecF)
AHNNCTC12129_04761(rffT)
YREHEC60_18715
SGOEA8O29_021760
KINAB182_24220
PDZHHA33_01225
IZHFEM41_06605
PSHISAMEA2665130_3006(wecF)
PSGCG163CM_34180(wecF)
EBFD782_4360
EBCC2U52_07180
EBUCUC76_14645
PSTSE05_20680
YPEYPO3857
YPKy0371(wecF)
YPHYPC_0365
YPAYPA_0161
YPNYPN_0106
YPMYP_3188(wecF1)
YPPYPDSF_3475
YPGYpAngola_A0521(wecF)
YPZYPZ3_3411
YPTA1122_06525
YPDYPD4_3403
YPXYPD8_3403
YPWCH59_1800
YPJCH55_3153
YPVBZ15_3851
YPLCH46_1204
YPSYPTB0177
YPOBZ17_2412
YPIYpsIP31758_0191(wecF)
YPYYPK_4024
YPBYPTS_0189
YPQDJ40_2247(wecF)
YPUBZ21_3528
YPRBZ20_1948
YPCBZ23_3800
YPFBZ19_3635
YENYE0178
YEPYE105_C0181
YEYY11_33761
YELLC20_05064
YEWCH47_3307(wecF)
YETCH48_1871
YEFFORC2_3920
YEEYE5303_41221
YSIBF17_08880
YALAT01_2293
YFRAW19_3029(wecF)
YINCH53_1981
YKRCH54_2759
YROCH64_2767
YRUBD65_1769
YRBUGYR_09370
YAKACZ76_10105
YMADA391_21960
YHID5F51_00945
YCAF0T03_00915
YMOHRD69_04295
SMARSM39_4330(rffT)
SMACSMDB11_4274(rffT) SMDB11_4639
SMWSMWW4_v1c01800(rffT)
SPESpro_0170
SRRSerAS9_0132
SRLSOD_c01260(wecF)
SRYM621_00630
SPLYQ5A_000725(wecF)
SRSSerAS12_0132
SRASerAS13_0131
SMAFD781_0138
SLQM495_00670
SERFL085_05270
SERSSERRSCBI_00750
SFWWN53_09250
SFGAV650_01735
SRZAXX16_0389
SERASer39006_003845
SERQCWC46_03845
SERMCLM71_00755
SQUE4343_15440
SFJSAMEA4384070_0133(wecF)
SOFNCTC11214_01916(wecF)
SSURATE40_021575 ATE40_023260
SURIJ0X03_23185
SRHZFO014_09260
SFOZ042_12845
RAHRahaq_4255
RACEJHW33_15660
RAQRahaq2_4368
RAAQ7S_21630
ROXBV494_17770
RVCJ9880_06785
GQUAWC35_10745
FSMCCS41_11845
EAMEGXP68_20350
RBADH2866_08935
ECAECA4202(wecF)
PATREV46_20960
PATOGZ59_42660(wecF)
PCTPC1_4002
PCCPCC21_039810
PCVBCS7_20015
PWAPecwa_4194
PPARA8F97_20510
PECW5S_4357
PWSA7983_06115
PPOABJK05_15000
PBRAB5S52_01195
PPUJE2566_20355
PARII2D83_01255
PAQUDMB82_0019210
PVZOA04_42710(wecF)
PPAVLOZ86_02290
DDDDda3937_00275(rffT)
DZEDd1591_0165
DDCDd586_3892
DZCW909_18965
DSOA4U42_07600
CEDLH89_13885
DFNCVE23_20985
DDQDDI_3999
DAQDAQ1742_04238(rffT)
DICDpoa569_000262
DDADd703_0210
BGJAWC36_20060
BRBEH207_16135
BNGEH206_01330
BIZHC231_01315
LBQCKQ53_04160
LPOPI6N93_00945
SGLSG2376
SODSant_0298
EAMEAMY_0180(wecF)
EAYEAM_0173(rffT)
ETAETA_02060(wecF)
EPYEpC_01940(wecF)
EPREPYR_00203(wecF)
EBIEbC_02030(wecF)
ERJEJP617_13920(wecF)
EGEEM595_3327(wecF)
EPECI789_17715
ERWIGN242_20160
ETPLU633_24945
PAMPANA_0156(wecF)
PLFPANA5342_4271(wecF)
PAJPAJ_3316(wecF)
PAQPAGR_g4122
PVAPvag_3391(wecF)
PAGGAL522_05090
PAOPat9b_0149
KLNLH22_01515
PANTPSNIH1_06315
PANPPSNIH2_16580
PAGCBEE12_07475
PSTWDSJ_22165
PALHB1H58_08560
PANSFCN45_00770
PEYEE896_18355
PDISD8B20_00625
PERLAC65_00420
PGZC2E15_20325
PCDC2E16_19745
MINTC7M51_03209(wecF)
MTHIC7M52_03790(wecF)
TCIA7K98_18790
TPTYNCTC11468_03533(wecF)
PLUplu4653(wecF)
PLUMA4R40_23080
PAYPAU_04133(wecF)
PTTVY86_06555
PAKHB0X70_23520
PLUICE143_23560
PMRPMI3325(rffT)
PMIBBB2000_3357(rffT)
PVLAOB99_01045
PVGCRN77_03030
PHAUPH4a_08075
PROTBTA34_17850
PCOLF1325_01005
PCIBF9282_01005
PPEEI6G31_08370
XBOXBJ1_4169(rffT)
XBVXBW1_4524(wecF)
XNEXNC1_0393(rffT)
XNMXNC2_0385(rffT)
XDOXDD1_0355(wecF)
XPOXPG1_3475(wecF)
XHOA9255_14185
XBUHGO23_18230
PSIS70_11685
PSXDR96_843(wecF)
PSTABGK56_14615
PRGRB151_042110(wecF)
PALACO695_05760
PHEINCTC12003_03730(wecF)
PRQCYG50_17680
PRJNCTC6933_03744(wecF)
PVCG3341_18320
MMKMU9_246
ANSArsFIN_02220(wecF)
AEDE3U36_04190
AETLDL57_00985
MWIMNY66_14790
EICNT01EI_0099
ETRETAE_0110(wecF)
ETDETAF_0083
ETEETEE_1871
ETCETAC_00410
EDWQY76_02305
EDLAAZ33_00420
EHOA9798_16280
HAVAT03_01740
HPARAL518_03865
OPODSM2777_02260
LPVHYN51_09705
PFQQQ39_17690
PRAGEKN56_00965
LRINCTC12151_03584(wecF)
HDUHD_1836(wecF)
HAPHAPS_1061(wecF)
HPAZK756_01465
HPAKJT17_09625
GLECJD39_10775
MHTD648_23630
MHQD650_2550
MHATB824_3610
MHXMHH_c03440
MHAEF382_09235
MHAOJ451_07000
MHALN220_12980
MHAQWC39_01280
MHAYVK67_01285
MVRX781_2190
MVIX808_19380
MVGX874_18160
MVEX875_1810
MGRAA4G16_10690
MBOSICJ55_03500
APLAPL_1545(wecF)
APJAPJL_1573(wecF)
APAAPP7_1607(wecF)
ASIASU2_09905
ASSASU1_09950
AEUACEE_09190
AIOEXH44_07105
ALIGNCTC10568_01899(wecF_1)
BTOWQG_3530
BTREF542_18430
BTRHF543_20310
BTRAF544_3940
OOIA6A10_01425
FCLA4G17_03550
TBVH9L17_00515
VSHBSZ05_05040
MARAD0851_05405
IDICWC33_02970
IDTC5610_02505
COMCMT41_10680
PPISB1L02_14680
PEAPESP_a0467
PDJD0907_14785
APELCA267_014315
PMESFX988_03854
LALAT746_12840
FPZLA55_1370
FPJLA02_1154
TUNJ9260_17555
THIMKFB96_06595
HBEBEI_1674(wecF)
ALNAS19_09760
MGEOCFI10_15815
AEAC2U39_14455
BCIBIM45_423
NBACUN60_12215
HWIA0Z60_07555 A0Z60_07580
ACREACRYA_0144
ALANALANTH_2109
AVPAVENP_2919
NAPC3L23_08595
DAXFDQ92_00595
CEUA7L45_18675
TMEDDWB79_01375
FHWRN87_00930
PJECRM71_04845
PNIJ5A59_08545
BLQL21SP5_01967
COYHF329_17530
OLIFKG96_06990
CAMUCA2015_3030
CHKD4L85_22095 D4L85_31200
GRLLPB144_02075
MAREEJ994_13080
LVNBWR22_10565
AQBD1818_14355
MESQC7H62_1946
MARXINR76_00310
CTAK4412677_01816(wecF)
CCASEIB73_09145
EBVF0358_02375
PRSB9H02_08730
FIANA23_00710 NA23_09220
DTNDTL3_1010
MEFMSWH1_3005
MSZMSSIH_2387
 » show all
Reference
1  [PMID:11673418]
  Authors
Rahman A, Barr K, Rick PD
  Title
Identification of the structural gene for the TDP-Fuc4NAc:lipid II Fuc4NAc transferase involved in synthesis of enterobacterial common antigen in Escherichia coli K-12.
  Journal
J Bacteriol 183:6509-16 (2001)
DOI:10.1128/JB.183.22.6509-6516.2001
  Sequence
[eco:b4481]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.1.325
IUBMB Enzyme Nomenclature: 2.4.1.325
ExPASy - ENZYME nomenclature database: 2.4.1.325
BRENDA, the Enzyme Database: 2.4.1.325

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