KEGG ENZYME: 2.5.1.56

ENZYME: 2.5.1.56

Entry

EC 2.5.1.56                 Enzyme

Name

N-acetylneuraminate synthase;
(NANA)condensing enzyme;
N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating);
NeuAc synthase

Class

Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

Sysname

phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)

Reaction(IUBMB)

phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate [RN:R01804]

Reaction(KEGG)

R01804;
(other) R04435

Substrate

phosphoenolpyruvate [CPD:C00074];
N-acetyl-D-mannosamine [CPD:C00645];
H2O [CPD:C00001]

Product

phosphate [CPD:C00009];
N-acetylneuraminate [CPD:C00270]

History

EC 2.5.1.56 created 1972 as EC 4.1.3.19, transferred 2002 to EC 2.5.1.56

Pathway

ec00541

Biosynthesis of various nucleotide sugars

ec01100

Metabolic pathways

Orthology

K01654

N-acetylneuraminate synthase

K05304

sialic acid synthase

Genes

HSA:	54187(NANS)

PTR:	743934(NANS)

PPS:	100982112(NANS)

GGO:	101124502(NANS)

PON:	100446862(NANS)

PPYG:

129043970(NANS)

NLE:	100603154(NANS)

HMH:	116475313(NANS)

SSYN:

129479125(NANS)

MCC:	715459(NANS)

MCF:	102120030(NANS)

MTHB:

126938070

MNI:	105477199(NANS)

CSAB:

103219150(NANS)

CATY:

105593048(NANS)

PANU:

101020165(NANS)

TGE:	112607835(NANS)

MLEU:

105549289(NANS)

RRO:	104657773(NANS)

RBB:	108539113(NANS)

TFN:	117098940(NANS)

PTEH:

111536614(NANS)

CANG:

105509947(NANS)

CJC:	100411585(NANS)

SBQ:	101027621(NANS)

CIMI:

108303891(NANS)

ANAN:

105733368(NANS)

CSYR:

103273474(NANS)

MMUR:

105873791(NANS)

LCAT:

123645941(NANS)

PCOQ:

105805371(NANS)

OGA:	100951418(NANS)

MMU:	94181(Nans)

MCAL:

110292645(Nans)

MPAH:

110323062(Nans)

RNO:	298071(Nans)

MCOC:

116095967(Nans)

ANU:	117709646(Nans)

ASYL:

127680771(Nans)

MUN:	110551128(Nans)

CGE:	100767837(Nans)

MAUA:

101830178(Nans)

PROB:

127224641(Nans)

PLEU:

114702354(Nans)

MORG:

121458558(Nans)

MFOT:

126509881

AAMP:

119826497(Nans)

NGI:	103749137(Nans)

HGL:	101721582(Nans)

CPOC:

100716456(Nans)

CCAN:

109697287(Nans)

DORD:

105990839(Nans)

DSP:	122121805(Nans)

PLOP:

125345837(Nans)

NCAR:

124964919

MMMA:

107147766(Nans)

ITI:	101969015(Nans)

OCU:

100356934

OPI:	101522937(NANS)

TUP:	102496776(NANS)

GVR:	103590728(NANS)

CFA:	481624(NANS)

CLUD:

112649641(NANS)

VVP:	112930767(NANS)

VLG:	121494904(NANS)

NPO:	129495242(NANS)

AML:	100471912(NANS)

UMR:	103678504(NANS)

UAH:	113260417(NANS)

UAR:	123781029(NANS)

ELK:

111146174

LLV:

125083268

MPUF:

101687668(NANS)

MNP:	132024576(NANS)

MLK:	131812492(NANS)

NVS:	122917426(NANS)

ORO:	101377441(NANS)

EJU:	114213569(NANS)

ZCA:	113934273(NANS)

MLX:	118017911(NANS)

NSU:	110581438(NANS)

LWW:	102730978(NANS)

FCA:	101092303(NANS)

PYU:	121034713(NANS)

PCOO:

112872235(NANS)

PBG:	122474611(NANS)

PVIV:

125149821(NANS)

LRUF:

124502196

LGF:	123593273(NANS)

AJU:

106981299

PTG:	102952743(NANS)

PPAD:

109270098(NANS)

PUC:

125920084

PLEZ:

122204412(NANS)

HHV:	120233531(NANS)

BTA:	540602(NANS)

BOM:	102266035(NANS)

BIU:	109563072(NANS)

BBUB:

102402717(NANS)

BBIS:

104993691(NANS)

CHX:	102171423(NANS)

OAS:	101104048(NANS)

BTAX:

128052274(NANS)

CSUM:

138081240(NANS)

ODA:	120862645(NANS)

CCAD:

122452923(NANS)

MREE:

136148472(NANS)

OVR:	110145332(NANS)

MBEZ:

129556850(NANS)

SSC:	100155883(NANS)

CFR:	102511644(NANS)

CBAI:

105067382(NANS)

CDK:	105086903(NANS)

VPC:	102528094(NANS)

BACU:

103016138(NANS)

BMUS:

118897102(NANS)

LVE:	103074242(NANS)

OOR:	101286113(NANS)

LALB:

132523500(NANS)

DLE:	111187968(NANS)

PCAD:

102975186(NANS)

PSIU:

116755813(NANS)

NASI:

112392669(NANS)

ECB:	100064126(NANS)

EPZ:	103550229(NANS)

EAI:	106842931(NANS)

MYB:	102254698(NANS)

MYD:	102770256(NANS)

MMYO:

118667273(NANS)

MLF:	102435662(NANS)

MDT:	132212182(NANS)

MYUM:

139020982(NANS)

PKL:	118716275(NANS)

EFUS:

103286401(NANS)

MNA:	107544993(NANS)

DRO:	112304493(NANS)

SHON:

118979589(NANS)

AJM:	119045927(NANS)

PDIC:

114509777(NANS)

PHAS:

123819942(NANS)

MMF:	118629683(NANS)

PPAM:

129079673(NANS)

HAI:	109386412(NANS)

RFQ:	117032312(NANS)

PALE:

102882391(NANS)

PGIG:

120597479(NANS)

PVP:	105296243(NANS)

RAY:	107511690(NANS)

MJV:	108386331(NANS)

TOD:	119231857(NANS)

SARA:

101558462(NANS)

SFUM:

130026316(NANS)

SETR:

126023700(NANS)

LAV:	100659127(NANS)

TMU:

101361417

ETF:	101653381(NANS)

DNM:	101415935(NANS)

MDO:	100014569(NANS)

GAS:	123231260(NANS)

SHR:	100915225(NANS)

AFZ:

127560750

PCW:	110220562(NANS)

TVP:	118834988(NANS)

PBRV:

138166878(NANS)

OAA:	100074951(NANS)

TACU:

119948107(NANS)

GGA:	427283(NANS)

PCOC:

116234839(NANS)

MGP:	100540972(NANS)

CJO:	107306381(NANS)

TPAI:

128089605 128089615

LMUT:

125687047 125687392

NMEL:

110389693(NANS)

APLA:

101793548(NANS)

ACYG:

106046483(NANS)

CATA:

118256861(NANS)

AFUL:

116500909(NANS)

TGU:	100227675(NANS)

LSR:	110472303(NANS)

SCAN:

103821217(NANS)

PMOA:

120509468(NANS)

OTC:	121334701(NANS)

PRUF:

121355663(NANS)

ATRC:

139588866(NANS)

GFR:	102036907(NANS)

FAB:	101817049(NANS)

OMA:	130264714(NANS)

PHI:	102108606(NANS)

PMAJ:

107198262(NANS)

CCAE:

111940921(NANS)

CCW:	104689769(NANS)

CBRC:

103616433(NANS)

ACOE:

138103000(NANS)

ETL:	114056942(NANS)

ZAB:	102065706(NANS)

ZLE:	135460015(NANS)

ACHL:

103804865(NANS)

SVG:	106859673(NANS)

MMEA:

130577596(NANS)

HRT:	120765301(NANS)

SATI:

136374431(NANS)

CCIC:

134056231(NANS)

FPG:	101910977(NANS)

FCH:	102058691(NANS)

CCRI:

104155775(NANS)

NNT:	104409114(NANS)

SHAB:

115601192(NANS)

ACUN:

113489989(NANS)

TALA:

104366421(NANS)

ACHC:

115336739(NANS)

HALD:

104312067(NANS)

HLE:	104830508(NANS)

AGEN:

126036494

HHAR:

128136549(NANS)

GCL:

127027665

CSTI:

104550675(NANS)

LDI:	104355132(NANS)

MNB:	103774718(NANS)

DPUB:

104304859(NANS)

PPUS:

135173207(NANS)

AVIT:

104274354(NANS)

BRHI:

104489142(NANS)

EGZ:	104135026(NANS)

NNI:	104014067(NANS)

PCRI:

104025538(NANS)

PCAO:

104046970(NANS)

PADL:

103923247(NANS)

AFOR:

103896158(NANS)

FGA:	104074239(NANS)

GSTE:

104263825(NANS)

CBOY:

140651032(NANS)

CLV:	102088004(NANS)

PGUU:

104469406(NANS)

PLET:

104620779(NANS)

EHS:	104517044(NANS)

CMAC:

104481639(NANS)

CUCA:

104059924(NANS)

TEO:	104375228(NANS)

OHA:	104331297(NANS)

ACAR:

104518859(NANS)

CPEA:

104394483(NANS)

CVF:	104285719(NANS)

RTD:	128902703(NANS)

CRID:

134508272(NANS)

AAM:	106487451(NANS)

AROW:

112968978(NANS)

NPD:	112946284(NANS)

TGT:	104577698(NANS)

DNE:	112982754(NANS)

SCAM:

104151902(NANS)

ASN:	102371122(NANS)

AMJ:	102562418(NANS)

CPOO:

109323518(NANS)

CMY:	102930222(NANS)

CCAY:

125636602(NANS)

DCC:	119855742(NANS)

CPIC:

101940249(NANS)

TST:	117878892(NANS)

CABI:

116832497(NANS)

MRV:	120408042(NANS)

ACS:	100558551(nans)

ASAO:

132768113(NANS)

PVT:	110077827(NANS)

SUND:

121924222(NANS)

PBI:	103051012(NANS)

PMUR:

107293127(NANS)

CTIG:

120308567(NANS)

TSR:	106556782(NANS)

PGUT:

117661676(NANS)

APRI:

131193653(NANS)

PTEX:

113444069(NANS)

NSS:	113415520(NANS)

VKO:	123030229(NANS)

PMUA:

114587657(NANS)

PRAF:

128405086(NANS)

ZVI:	118097903(NANS)

HCG:	128346307(NANS)

GJA:	107122992(NANS)

STOW:

125437185(NANS)

EMC:	129334514(NANS)

XLA:	432051(nans.S) 447417(nans.L)

XTR:	100492893(nans)

NPR:	108783786(NANS)

RTEM:

120946942(NANS)

BBUF:

120989333(NANS)

BGAR:

122920937(NANS)

PWL:	138299440 138299488 138299495

MUO:	115459142 115463653

GSH:	117347248 117347256

DRE:	322780(nansa) 492779(nansb)

SRX:	107723182 107754352 107754390 107758866

SANH:

107665955 107686966 107686967 107692601

SGH:	107557947 107566238 107566239

CCAR:

109080082 109090623 109090659 122142494

CAUA:

113044320 113066551 113066555 113066556 113066635 113085422 113105679

CGIB:

127946856 127946857 127948763 127975766

PTET:

122322880(nansa)

LROH:

127156361(nansb) 127172436(nansa)

OMC:	131524664 131534998(nansb) 131541588(nansa)

PPRM:

120475377(nansb) 120475384 120475385 120475386 120478311(nansa)

RKG:	130097610 130097653 130106509 130106510

MAMB:

125247499 125247713 125247908 125247921 125248041 125251616 125251645 125272478(nansa)

CIDE:

127507296 127519832

CERY:

137014595 137014597 137015002 137015052 137015105 137015157 137032172(nansa)

MASI:

127443667 127445253

TROS:

130553152(nansa)

TDW:	130407907(nansa) 130414328 130414329 130414351 130414352 130414355 130414375

MANU:

129433135 129433751 129444857(nansa) 129445965

PDAB:

135718171 135735826(nansa) 135745220 135781109 135781110 135787861 135787864

IPU:	100528493(nansa) 108260162

IFU:	128603812 128604222(nansa)

PHYP:

113531522(nans)

SMEO:

124378730 124381237(nansa)

TFD:	113635339(nansa)

TVC:	132842025(nansa)

CGAR:

128508667(nansa) 128511979

NGRA:

132875401 132875934 132882784 132883322

TRN:	134326114 134326424(nansa) 134327107

AMEX:

111195185(nansa) 125798999(nansb)

CMAO:

118811935 118811936 118816978(nansa)

EEE:	113568448(nans) 113589926

CHAR:

105903578(nansa)

SPIL:

134060036(nansa) 134094212

TRU:	778024(nans)

TFS:	130527938(nansa)

TNG:	GSTEN00033532G001

LCO:	104922341(nans)

TBEN:

117474709(nansa)

CGOB:

115010173 115010214

PGEO:

117439291(nansa) 117450755

GACU:

117555257 117561263(nansa) 117561638

EMAC:

134864542(nansa)

ELY:	117254746(nansa)

EFO:	125885917(nansa)

PLEP:

121942582(nansa)

SLUC:

116042899(nansa)

ECRA:

117956637(nansa)

ESP:	116698406(nans)

PFLV:

114570372(nans)

GAT:	120825501 120825503

PPUG:

119218410(nansa)

AFB:	129095925 129096028(nansa)

CLUM:

117737471(nansa)

PSWI:

130190092(nansa)

CANA:

137795113 137795188

CVE:	137885278 137885382(nansa)

MSAM:

119884880 119899378 119899379

SCHU:

122873785 122873786

CUD:	121507902 121508708 121508709

SPUL:

138594617(nansa)

LMIX:

132985410 132985440

ALAT:

119028006

ASTR:

137599651 137600245

MZE:	101481190 106674567

ONL:	100695579 100695847 100696106

OAU:	116310552 116310553 116310587

OLA:	101166198(nans)

OML:	112137589(nansa)

CSAI:

133444310(nansa)

XMA:	102234709(nans)

XCO:	114145362(nans)

XHE:	116720640(nans)

PRET:

103467988(nans) 103472627

PFOR:

103148741(nans)

PLAI:

106938624(nans)

PMEI:

106905478(nans)

GAF:	122829775(nansa)

PPRL:

129367361(nansa)

CVG:	107083396(nans) 107083415 107083416

CTUL:

119787144 119787154 119787177

GMU:	124868545 124868562

NFU:	107390917 107390934

KMR:	108241432 108241509

ALIM:

106528334(nans)

NWH:	119422378 119422379

AOCE:

111575007(nansa)

EJA:	138208666 138208668 138209314 138209396 138209520 138209521

BFRE:

138614487 138615127

MCEP:

125003896 125004087 125004788

CSEM:

103384124 103384125

POV:	109627210 109627438

SSEN:

122770577 122771631

SSOE:

131466991 131466992

HHIP:

117769790 117769798

HSP:	118122966 118126039

PPLT:

128436994 128436995

SMAU:

118312620 118312971

LCF:	108885367 108885368

SDU:	111229256 111229269

SLAL:

111659703

XGL:	120800959(nansa)

HCQ:	109519806 109519931

SSCV:

125969199 125969200

SBIA:

133506019 133506020

PEE:	133404376 133404378

PTAO:

133476244 133476245

BPEC:

110166192 110166235

ENY:	140376541 140377163 140377164 140377250

MALB:

109953770(nans)

BSPL:

114858266 114858277 114858282

SJO:	128374734(nansa)

SSCO:

133988251(nansa)

GMH:	115540714(nans)

SASA:

100195066(sias) 106594767 106609889

STRU:

115191851 115202178 115202179 115202180 115202181

OTW:	112231840 112261351

OMY:	110497423 110497424 110534455

OGO:	124001941 124001943 124012735

ONE:	115137363 115137722 115145762 115146546

OKI:	109894131 109901155

OKE:	118362993 118362994 118395463

OMM:	135506831 135507743 135507744

OCLA:

139374135 139374136 139418884

SALP:

111971593 112068285 112080022

SNH:	120034903 120051990 120052901

CCLU:

121534521 121535761 121535762

ELS:	105022900(nans)

OEP:	134034363(nansa)

SFM:

108920829

PKI:	111855408(nans)

AANG:

118227907(nansa)

AROT:

135255851(nansa)

CCOG:

133131112(nansa)

LOC:	102687418(nans)

PSPA:

121319344(nansa)

ARUT:

117420829(nansa)

PSEX:

120532357 120532358 120532359

CMK:	103177631(nansa) 103177633

RTP:	109938218(nansa)

CPLA:

122539555(nansa) 122547124

HOC:	132833232(nansa)

LERI:

129702205(nansa)

PMRN:

116951617(NANS)

LRJ:

133340871

BFO:	118412951 118412952

BBEL:

109471483 109471485

SCLV:

120347367

SPU:

577884

LPIC:

129272734

AJJ:

139967908

APLC:

110979925

ARUN:

117294985

AAMU:

139941046

AFIL:

140162881

AJC:

117102584

SKO:	100367009 100376912

PFLL:

139119946

DME:	Dmel_CG5232(NANS)

DER:

6553702

DSE:

6606666

DSI:	Dsimw501_GD18832(Dsim_GD18832)

DYA:	Dyak_GE26192

DSR:

110190443

DPO:

4800832

DPE:

6598731

DMN:

108156913

DWI:

6650267

DGR:

6568185

DMO:	Dmoj_GI24828

DAZ:

108621816

DNV:

108653385

DHE:

111601415

CCAT:

101459749

BOD:

106619099

BDR:

105230863

RZE:

108365099

AOQ:

129252978

ALUD:

128865303

TDA:

119676011

MDE:

101899077

SCAC:

106086863

LCQ:

111687367

LSQ:

119609198

CVJ:	135949017(NANS)

GFS:

119638352

ECOE:

129939471

CLON:

129606515

HIS:

119658663

AGA:

133390932

ACOZ:

120950612

AARA:

120897604

AMER:

121589583

ASTE:

118508544

AMAP:

126558334

AFUN:

125763207

AMOU:

128309712

AMRS:

128707124

AALI:

118457210

ACOS:

131261000

AAG:

5563645

AALB:

109400878

ASUA:

134225434

CQU:	CpipJ_CPIJ013964

CPII:

120415920

CBRI:

134826934

CNS:

116345828

BCOO:

119073869

LLL:

129794412

PPAP:

129802692

TCA:

103312199

TMOL:

138134526(NANS)

DPA:

109539228

ESIM:

136414094(NANS)

EFOR:

136340738(NANS)

SOY:

115879752

AGRG:

126744310

ATD:

109597067

CSET:

123315673

HAXR:

123680853

AGB:

108917229

LDC:

111503205

DVV:

114325108

NVL:

108567369

APLN:

108741788 112904754

PPYR:

116164831

BMOR:

101744099

BMAN:

114246626

MSEX:

115444962

DPL:	KGM_201756

BANY:

112054184

MJU:

123873286

NIQ:

126781032

VCD:

124533422

MCIX:

123656177

PMAC:

106708951 106709065

PPOT:

106100777 106100789

PXU:	106124172 106124788

BPHI:

137926582 137926679

PRAP:

110994857

PBX:

123716686

PNAP:

125054681

ZCE:

119829783

CCRC:

123693416

LSIN:

126969391

AAGE:

121730324

HAW:

110380482

HZE:

124629863

TNL:	113496613 113506267

SLIU:

111353605

OFU:

114364386

ONU:

135088530

ATRA:

106138180

GMW:

113518207

PXY:

105391284

PGW:	126373167 126377162

LGLY:

125225310

CSTB:

134755939

CCRN:

123298907

API:	100166349 100570600

DNX:

107161705

AGS:	114120104 126550715

RMD:

113549718

ACOO:

126833023

DVT:

126896132

BTAB:

109035180

DCI:

103520284

CLEC:

106666066

HHAL:

106681070(NANS)

NLU:

111058090

HVI:

124352678

PHU:	Phum_PHUM018360

FOC:

113212662

TPAL:

117647422

ZNE:

110829049

CSEC:

111874253

PAME:

138692648(NANS)

SGRE:

126267101

BROR:

134530381

IEL:

124155457

HAMR:

139694341(NANS)

FCD:

110842189

DPX:	DAPPUDRAFT_300651

DMK:

116933060

DPZ:

124349840

AFRA:

136025080

PVM:	113802701(NANS)

PJA:

122265930

PCHN:

125046868

PMOO:

119575012

HAME:

121873235

PCLA:

123769285(NANS)

CQD:	128690230(NANS)

PTRU:

123507890

ESN:

126997930

MNZ:

135214269

MRJ:	136854945(NANS)

PORN:

139749074(NANS)

HAZT:

108677748

EAF:

111695997

PPOI:

119112814 119113236

VDE:

111250001

VJA:

111258697

TUT:

107368038

CSCU:

111619307

CVS:	136989545(NANS)

PTEP:

107452120

ABRU:

129958113 129958114 129958115

UDV:

129218419

SDM:

118205491

LPOL:

106468194

MMER:

123559815

AAF:	AURANDRAFT_30675

EHX:	EMIHUDRAFT_437804(NEUB)

ECOO:

ECRM13514_2762(nnaB)

ECOH:

ECRM13516_2630(nnaB)

ESL:

O3K_09230

ESO:

O3O_16390

ESM:

O3M_09195

ECK:	EC55989_2295

ECV:	APECO1_3471(neuB)

ECM:	EcSMS35_3232(neuB)

ECT:	ECIAI39_3443(neuB)

EOC:	CE10_3481(neuB)

ECI:	UTI89_C3372(neuB)

EIH:	ECOK1_3369(neuB)

ECZ:	ECS88_3330(neuB)

ECOI:

ECOPMV1_03252(spsE)

SBZ:

A464_2222

SBV:	N643_09315

PPAV:

LOZ86_01605

PMAK:

PMPD1_2835

PTT:	VY86_07610

EIC:	NT01EI_1316

ETD:

ETAF_1122

ETE:	ETEE_3151(neuB)

ETR:	ETAE_1207(neuB)

ETC:	ETAC_05745

EDW:	QY76_14240

EDL:	AAZ33_06215(neuB)

EHO:	A9798_10695

HPR:	PARA_02850(nnaB)

MHT:	D648_18140(neuB)

MHQ:	D650_8020(neuB)

MHAT:

B824_18220(neuB)

MHX:	MHH_c26670(nnaB)

MHAE:

F382_04090

MHAM:

J450_03120

MHAO:

J451_04330

MHAL:

N220_10190

MHAQ:

WC39_04015

MHAY:

VK67_04015

MVR:

X781_5990

MVI:	X808_15570

MVG:	X874_14510

MVE:

X875_5510

MGRA:

A4G16_01260

MBOS:

ICJ55_05335(neuB)

ASI:	ASU2_01185 ASU2_10545

ASS:	ASU1_01190

AEU:	ACEE_01045

ADP:	NCTC12871_01316(spsE)

AART:

NYR89_08600(neuB)

AGK:	NYR60_07115(neuB)

APAG:

EIA51_04610(neuB)

RPNE:

NCTC8284_01156(spsE)

RHEY:

FEE42_11160(neuB)

PBAN:

AC062_1737

VOW:	A9237_07155

VNL:	D3H41_01125

VCRA:

IS519_09525

VSA:	VSAL_I3011(neuB)

PGB:	H744_2c2918

MBOI:

DQF64_00690(neuB)

MNC:	LU297_05635(neuB)

SBK:	SHEWBE_0694(siaC)

ILO:	IL0519(siaC)

ILI:	K734_02600

IDP:	U0358_02705(neuB)

PAEW:

KIH87_04060

FES:	HER31_10795

MVS:	MVIS_3782(siaC)

CEG:	D0C16_04765

GJP:	R50076_16880

MMAI:

sS8_2961

MISZ:

MishRS11D_42600

FSR:	KQR59_06225

COBB:

H2O77_12280

IFO:	CVFO_1265(neuB)

NME:	NMB0068(siaC)

NMP:	NMBB_0073(siaC)

NMH:	NMBH4476_0068

NMD:	NMBG2136_0075

NMM:	NMBM01240149_0067

NMS:	NMBM01240355_0070

NMQ:	NMBM04240196_0082(siaC)

NMZ:	NMBNZ0533_0074(siaC)

NMC:	NMC0052(siaC)

NMN:	NMCC_0076(siaC)

NMT:	NMV_0069(siaC)

NWE:	SAMEA3174300_1366(siaC)

NBL:	GJV52_06945(siaC)

SMUR:

BWP33_01885

RPJ:	N234_26965

PIU:	AOC20_01690

BPSI:

IX83_06875

NCO:	AAW31_00110

NMU:	Nmul_A0408

NLC:	EBAPG3_000870

SLAC:

SKTS_36140

DDEN:

KI615_14890

AHV:	AADV58_14530

EAK:	EKH55_4784

EAH:	FA04_24335

REL:	REMIM1_CH00773

RLG:

Rleg_0440

RHV:	BA939_07200

RRG:	J3P73_04755

BSEI:

KMZ68_19010

RPE:

RPE_4236

MMYR:

MXMO3_03623

BVR:

BVIR_1970

BLAG:

BLTE_00400(neuB)

CMET:

K6K41_27370

HDI:	HDIA_0896(pseI)

LAP:	ACP90_17630

LABR:

CHH27_23610

LABT:

FIU93_24290(neuB)

LAGG:

B0E33_01050 B0E33_04290

SIW:	GH266_06020

CAK:

Caul_2713

ASTI:

Q1W73_06370

MALG:

MALG_05073

PSEB:

EOK75_20575

PGV:	SL003B_2768

CBOT:

ATE48_13380

SPAN:

AWL63_07225

SPZR:

G5C33_06875

PALG:

HFP57_17520

CMAN:

A9D14_11725

AZZ:	DEW08_29995

RCE:	RC1_3771(nans)

DEX:	HWD60_03420

HFL:	PUV54_04660

ECOG:

FIV45_02370

TMK:	QGN29_13535

HMS:

HMU06150

HBL:	XJ32_01820

HET:	BBW65_04560

HCL:	NCTC13205_00838(spsE_2)

SULG:

FJR48_00820

CJE:	Cj1141(neuB1)

CJB:	BN148_1141(neuB1)

CJJ:	CJJ81176_1158

CJU:

C8J_1339

CJN:	ICDCCJ07001_1099

CJI:	CJSA_1083(neuB1)

CJP:	A911_05530

CJEJ:

N564_01107

CJEU:

N565_01150

CJEN:

N755_01145

CJEI:

N135_01178

CJY:	QZ67_01219(neuB)

CJL:	PJ17_05840

CJW:	PJ18_05655

CJZ:	M635_01405

CCOL:

BN865_09890c

CCY:	YSS_06165 YSS_07645

CIS:	CINS_1205(neuB)

CSM:	CSUB8521_1427(neuB)

CAVI:

CAV_0275(neuB)

CHW:	A2J15_001225

CUX:	CUP3940_0880(neuB)

CBLA:

CBLAS_1486(neuB)

CMUC:

CMCT_1128(neuB)

CNV:	CNZW441b_1143(neuB)

CVU:	CVULP_0717(neuB)

CMOL:

CMOL_0853(neuB)

SBA:	Sulba_1896

ABL:	A7H1H_1748

ARC:

ABLL_2687

ALK:

ALEK_0978

AHS:	AHALO_2546

AMYT:

AMYT_2597

HEBR:

AEBR_0577 AEBR_2874

PCA:	Pcar_1277(neuB)

DEF:	CNY67_09315

DFL:

DFE_1272

DMA:

DMR_13530

DCB:	C3Y92_14295

DGG:

DGI_4066

DMS:	E8L03_20250

DAF:	Desaf_0142

DAS:

Daes_2970

DPI:

BN4_12645

DEJ:	AWY79_17810

PPRF:

DPRO_1430

PSEL:

GM415_02085 GM415_02270

DDN:	DND132_2824

PSEF:

PSDVSF_27550

PPOR:

JCM14722_23280

PNW:

SYK_28560

PTHE:

LF599_15630

PMEN:

V8V93_05465

DSX:	GD604_00905

DSD:	GD606_11120

DVM:

DvMF_1832

DSF:

UWK_03120

DALK:

DSCA_06450

DVR:	Dvar_38620 Dvar_38830

TAV:	G4V39_08720

MRM:	A7982_08421

HOH:

Hoch_0346

OBG:	Verru16b_02050(legI)

LPRO:

PQO03_09635

TBE:	Trebr_1643

SSM:	Spirs_4263

BHP:	BHAMNSH16_00325

ABA:	Acid345_2841

GMA:	AciX8_3329

GRB:	GOB94_15720

ABAS:

ACPOL_2207

SUS:

Acid_2246

BHL:	Bache_2153

BFE:	K6V30_22135

BFIN:

BFINE_35920

BSA:	Bacsa_3466

MICA:

P0L94_06000

PCLR:

PC1C4_16490 PC1C4_23910

AIT:	AI2BBH_P070(neuB)

ANF:

AQPE_0360

ASX:	CDL62_03680

ALKQ:

M9189_10535

PGIN:

FRZ67_17740

FEI:	K9M53_13105

MUP:	A0256_06345

MUC:

MuYL_3260

MGK:	FSB76_19830

MRUB:

DEO27_006375

MMAB:

HQ865_03405

MJJ:	PQO05_17985

MSAB:

SNE25_10070

MUY:	SNE26_05430

ALM:	AO498_13975

SPIB:

G8759_19535

SENF:

GJR95_02495

RHOZ:

GXP67_24460

RSI:	Runsl_2328

RUN:	DR864_20420

RUP:	DTQ70_21560

HYG:	AUC43_17190

HYP:	A0257_12515 A0257_22870

HYZ:	AXW84_01635

HNV:	DDQ68_17445

HMT:	MTP16_14775

MSAA:

QYS49_35875

FYA:	KMW28_01745

CHRW:

KA713_16020

FPS:	FP1256(neuB)

FPC:	FPSM_02167

FPY:	FPG101_10860

FPO:	FPG3_03200

FPQ:	IB65_05915

FPV:	IA03_06020

FPW:	IA04_05925

FPK:	IA06_05960

FJO:

Fjoh_0305

FJG:	BB050_02206(legI)

FCO:	FCOL_12635

FGL:	EM308_00620

FCM:	BIW12_03115

FFA:	FFWV33_07925

FKI:	FK004_09130

FCR:	HYN56_01615

FSN:	GS03_01394(legI)

FNK:	E1750_14005

FFL:	HYN86_01540(neuB)

FEN:	J0383_14490

FCV:	AWN65_10295

FOE:	JJC03_00440(neuB)

FSD:	LXD69_00570(neuB)

FCB:	LOS89_02800(neuB)

FPB:	NLJ00_01825(neuB)

FBI:	L0669_01565

FCS:	TRV642_0311

FHU:	M0M44_01540(neuB)

FCU:	NOX80_07525(neuB)

FPEC:

Q1W71_13450

FAV:	LNP19_01380

FCG:	LNP23_01515(neuB)

FFV:	LNP22_01850

FLZ:	GIY83_23250(neuB)

FLR:	ABFU83_01395(neuB)

FLF:	FLGSB24_02890

FSF:	AABD74_01575(neuB)

CAT:	CA2559_07305

KDI:	Krodi_2064

DOK:	MED134_13631(neuB)

DDO:	I597_1525(legI)

DOD:	DCS32_01450

LAN:	Lacal_0114

LACI:

CW733_08000

LNU:	N7U66_19210

AEQU:

QCQ61_00775

NDO:

DDD_2293

NOM:	AAT17_10860

NSD:	BST91_07935

NOB:	CW736_00515

NUL:	R1T42_01410

NMF:

NMS_1735

PRN:	BW723_03025 BW723_09690

POLA:

BXQ17_03870

POA:	CW731_03490(neuB)

PPEC:

H9W90_03840(neuB)

PUN:	NQP51_04925

PHG:	KCTC32516_01882(legI)

WIN:

WPG_0171

WIJ:	BWZ20_04190

AHZ:	APS56_05280

TEN:	LPB136_04690

LUT:	Lupro_02285

SMIS:

LDL76_01760

OLL:	CW732_09090

OAQ:	DZC78_14805

FEK:	C1H87_05360(neuB)

FAY:	Q4Q34_01095

TAY:	JJL45_08245

TAJ:	C1A40_00900

AUE:	C5O00_09755

MARF:

CJ739_165

MLIL:

QLS71_013090

AQA:	D1815_16910

EMAR:

D1013_15690

PSYN:

E9099_01280

MESQ:

C7H62_1954

LPAL:

LDL79_03610(neuB)

SABU:

MBM09_06180

ALUT:

O5O44_12210

LUY:	QZH61_06910

HWS:	RNZ46_01605

FBQ:	D1817_12910

BBAU:

AEM51_01345

CTE:

CT0825

CPC:

Cpar_0852

CLZ:	BIU88_06970

CCH:

Cag_1072

CPH:	Cpha266_1187

CLI:

Clim_0797

PVI:

Cvib_1025

PLT:

Plut_1274

PPH:

Ppha_1574

PAA:

Paes_0910

PROC:

Ptc2401_00368(spsE)

PRS:	B9H02_06625

CTS:

Ctha_2574

IAL:	IALB_1518(neuB)

MRO:

MROS_1489

BCAO:

LC087_11900

OCN:	CUC15_16530(neuB)

LPAK:

GDS87_03420

HLI:

HLI_08585

VSS:	PD280_11965

GRC:	GI584_08485

BVJ:	I5776_04795

BOU:	I5818_06175

ACHP:

QR721_03740

LGZ:	NCTC10812_01041(spsE)

PYG:	AWM70_17110

PSPN:

L1F29_31635

SAG:	SAG1161(neuB)

SAN:

neuB

SAK:	SAK_1250(neuB)

SGC:	A964_1134(neuB)

SAGS:

SaSA20_0983(neuB)

SAGL:

GBS222_0993(neuB)

SAGM:

BSA_12390

SAGI:

MSA_12810

SAGR:

SAIL_12810

SAGP:

V193_05425

SAGC:

DN94_05425

SAGT:

GBSCOH1_1067

SAGE:

EN72_06455

SAGG:

EN73_05990

SAGN:

W903_1244(neuB)

SAGJ:

ID870_03555(neuB)

SSB:	SSUBM407_1280(neuB)

SSU:	SSU05_0578

SSV:	SSU98_0582

SSI:	SSU0535(neuB)

SSS:	SSUSC84_0517(neuB)

SSF:	SSUA7_0538

SSW:	SSGZ1_0571

SUP:

YYK_02535

SSUS:

NJAUSS_0543

SUI:	SSUJS14_0542

SUO:	SSU12_0539

SRP:	SSUST1_1227

SSUT:

TL13_1188(neuB)

SSUI:

T15_1401(neuB)

SRQ:	SR187_6425

AUH:	AWM75_07800

CBK:

CLL_A2336

CRW:	CROST_020640(legI)

CFB:	CLFE_020550(legI)

CAUN:

CLAUR_009290(legI)

HHW:	NCTC503_01053(spsE_1)

PROM:

QO263_18405

ACEL:

acsn021_05140

RGN:	RGna_11985(neuB)

SINT:

K5I26_06365(neuB)

LBX:

lbkm_3704

LBP:	V1224_13115

PSOR:

RSJ16_13965

TTO:	Thethe_00855

TIZ:	RBU61_14895

SDIA:

QU667_10085

STIM:

H1B31_05905

TUR:	AT726_03460

COB:	COB47_0921

CLC:	Calla_1077

MAUU:

NCTC10437_01405(spsE)

SCO:	SCO4881(2SCK8.07)

SALB:

XNR_3962

SMA:	SAVERM_3373(neuB)

SGR:

SGR_2659

SGB:

WQO_22260

SFI:

SFUL_4686

SANL:

KZO11_23545

SGRF:

SGFS_047150

SCYE:

R2B67_12580

SCB:	SCAB_35021

SSX:	SACTE_4137

SVL:	Strvi_8579

SHY:

SHJG_5999

SHO:	SHJGH_5761

SRC:	M271_28825

SMAL:

SMALA_3271

SSOI:

I1A49_20150

SFA:

Sfla_2375

SBH:

SBI_04660

SVE:

SVEN_4550

SDV:	BN159_3517

SALS:

SLNWT_4806

STRP:

F750_4425

SCI:	B446_22900

SLV:	SLIV_13970

SGU:	SGLAU_21015

SVT:	SVTN_23655

STRE:

GZL_03800

SCW:	TU94_20415

SLD:

T261_3148

SLC:	SL103_31275

SXI:	SXIM_34600

STRM:

M444_21440

STRC:

AA958_21930

SAMB:

SAM23877_4702

SPRI:

SPRI_2992

SCZ:	ABE83_12980

SCX:	AS200_19310

SRW:	TUE45_05421(legI)

STRF:

ASR50_22385

SLE:	sle_27930(sle_27930)

SRN:	A4G23_03558(legI)

SPAV:

Spa2297_20655

STRT:

A8713_19580

SCLF:

BB341_09760

SGS:	AVL59_05150

STSI:

A4E84_25245

SKY:	D0C37_21440

SALW:

CP975_21860

SGM:	GCM10017557_30090

SCAD:

DN051_15990

SPHW:

NFX46_04655

SGRS:

V9K83_12310

SLS:	SLINC_5269

SNR:	SNOUR_16850

SALU:

DC74_5067

SALL:

SAZ_27045

SPLU:

LK06_020555

STRD:

NI25_14545

SNW:	BBN63_12045

SAUO:

BV401_19850

SSIA:

A7J05_14200

SVU:	B1H20_22760

SPUN:

BFF78_16590

SGV:	B1H19_25585

SLAU:

SLA_4740 SLA_6887

SALF:

SMD44_05468

SALJ:

SMD11_2618

SLX:	SLAV_09960(legI1) SLAV_15140(legI2)

STRO:

STRMOE7_24205

SFK:

KY5_4998

SNZ:	DC008_21770

SGE:	DWG14_03226(legI)

SRJ:

SRO_2876

SLK:	SLUN_24770

SDX:	C4B68_15075

SGD:	ELQ87_14885

SCYA:

EJ357_28925

SAST:

CD934_06470 CD934_12310

SNQ:	CP978_20885

STIR:

DDW44_18845

SKA:	CP970_16280

SVN:	CP980_13090

SNK:	CP967_05875 CP967_12450

SHAW:

CEB94_25645

SRK:	FGW37_20385

SFIC:

EIZ62_12135

SGAL:

CP966_22765

SSPO:

DDQ41_21630

SPAD:

DVK44_22020

SFY:	GFH48_16540

SAQU:

EJC51_30275

SGF:	HEP81_03086

SCAV:

CVT27_21580

SSEO:

D0Z67_18105

SBY:	H7H31_21570

SRIM:

CP984_14855

SSUB:

CP968_13205

SPHV:

F9278_31615

SCIN:

CP977_21415

SFUG:

CNQ36_22015

SPAC:

B1H29_14045

SCHA:

CP983_16290

SGX:	H4W23_25065

SCOE:

CP976_27090

SBAT:

G4Z16_11340

SSPB:

CP982_26255

SNF:	JYK04_05256(legI)

SPLA:

CP981_24345

SBRO:

GQF42_26950

STUI:

GCM10017668_44270

SATA:

C5746_25680

SCHF:

IPT68_22475

SHUN:

DWB77_03039(legI)

SHAR:

HUT13_17550

SCYG:

S1361_24370(legI)

SFEU:

IM697_39420

SLIA:

HA039_12440

SDW:	K7C20_23210

SVD:	CP969_24060

SCAL:

I6J39_22415

SAUH:

SU9_021505

SFB:	CP974_19285

SMOB:

J7W19_20110

SPRA:

CP972_22240

SPEU:

CGZ69_22020

SROI:

IAG44_14945

SXN:	IAG42_13295

SGJ:	IAG43_19675

SHK:	J2N69_22950

SANU:

K7396_13775

STRY:

EQG64_22470

SDD:	D9753_13435

SACT:

DMT42_24315

SMAO:

CAG99_08790

SGOB:

test1122_17165

SINE:

KI385_28310

SLF:	JEQ17_18230

SDEC:

L3078_29100

SAOV:

G3H79_13490

SDUR:

M4V62_17340

SYAN:

NRK68_20945

SRUG:

F0345_09840

SAKB:

K1J60_16260

STAA:

LDH80_15810

SNIG:

HEK616_61380

SVIO:

HWN34_20045

SCAE:

IHE65_16520

STUB:

MMF93_20660

SSPN:

LXH13_16385

SCIR:

STRCI_005054

SXT:	KPP03845_104650(legI)

SLON:

LGI35_27380

SDRZ:

NEH16_11885

STUD:

STRTU_002595

STEE:

F3L20_04255

SGK:	PET44_20175

SANT:

QR300_25150

SYUN:

MOV08_16870

SARG:

HKX69_13055

SJN:	RI060_15285

SCYN:

N8I84_24810

SOV:	QZH56_12100

SFIY:

F0344_13015

SHAU:

K9S39_17715

SKG:	KJK29_12960

SCOA:

QU709_15335

SLAI:

P8A22_14570

SFP:	QUY26_14330

SINN:

ABB07_14525

STRZ:

OYE22_20720

SCAY:

PYS65_14025

KBU:	Q4V64_32670

SARM:

DVA86_26905

SPRF:

K4G22_10140

SLUO:

PS467_18060

STPB:

QR97_14440

SRPA:

HEP86_25415

SMIB:

SMIR_13490

SCAJ:

O1G22_16115

STRW:

QHG49_13840

STRL:

HEP84_31660

STSD:

HEP87_32790

SRPZ:

HEP85_24915

SCHE:

QRN89_21585

SGLY:

P8A20_13585

SCAT:

P8A18_21610

STII:

DRB96_20260

SABD:

N8I86_23655

STRV:

EZV63_22715

SPAZ:

ABXI76_13195

SPIH:

ABXR15_09090

SMOD:

POD33_17680

SPOF:

P8A21_24875

SCT:

SCAT_3775

SCY:	SCATT_37620

KAB:	B7C62_23005

STRI:

C7M71_012340

ABRY:

NYE86_30650

AGLA:

OIE69_16930

AREV:

RVR_6402

MIM:	AKG07_08990

MIX:	AB663_000207

MCW:	A8L33_09345

MICR:

BMW26_13440

MFOL:

DXT68_13545

MOO:	BWL13_02917(legI)

MPRT:

ET475_05105

MSED:

E3O41_07295

MOY:	CVS54_03075(legI)

MRN:	K8F61_13810

MLIQ:

NMQ05_14905

MTEC:

OAU46_11045

MNF:	JSY13_12270

MINV:

T9R20_10570

MEST:

PTQ19_15140

MOJ:	D7D94_04785

MSUF:

KV394_01405

MHOT:

PU630_15275

MGAB:

KV396_03035

MBET:

N8K70_01210

MICI:

AB2L57_08685

MALP:

QSU92_16075

RTX:	TI83_02490

RTC:	APU90_03985

RRY:	C1O28_12555

CUB:	BJK06_02800

CUG:	C1N91_04585

CQF:	GBG65_12140

CCIT:

QPK07_04970

CUF:	KM842_08475

CUY:	I8920_04655

CPOI:

OE229_07770

CURT:

LCG91_04725

CURZ:

LQK89_04925

AGY:	ATC03_06050

AGM:	DCE93_10975

AGF:	ET445_07850

AMAU:

DSM26151_22300(legI)

ASOI:

MTP13_09910

AMAV:

GCM10025877_06840

ALAV:

MTO99_09885

AIL:	FLP10_13185

PSAI:

C3B54_111626

MHUM:

NNL39_02705

MDB:	OVN18_02425

HUW:	FPZ11_09370

GRY:	D7I44_05085

LYK:	FLP23_10985

PLAP:

EAO79_15945

PFLU:

BWO91_12285

GLN:	F1C58_04720

HOM:	OF852_09430

ARL:	AFL94_17655

ARY:	ATC04_00745

ACRY:

AC20117_06350

ASUF:

MNQ99_01110

ARTQ:

CGQ24_00545

APN:	Asphe3_30650

AAI:	AARI_34160

GAR:	AOZ07_17865

GCR:	GcLGCM259_2956

GLU:	F0M17_16915

GPR:	JQN66_17680

GMI:	NMP99_17285

GMY:

XH9_08625

GNC:	QQS42_17255

GLM:	N6V40_02830

GEY:	QMQ05_16820

PAEY:

KUF55_18490

PALU:

CJ193_005445

JDE:

Jden_0843

PROU:

AB1046_12435

SANW:

G7063_04465

CGA:	Celgi_1077

CEZ:	CBP52_08110

CPAL:

F1D97_14765

BLY:	A2T55_13610

BLIN:

BLSMQ_3040

BRI:	FDF13_06745

BLUT:

EW640_07300

BCAU:

I6G59_00015

BSPO:

L1F31_13975

BREB:

PGC08_15095

BREJ:

LJ362_12835

SEVR:

LWF01_03420

MPH:

MLP_28480

MIK:	FOE78_14365

AER:	AERYTH_11775

MGG:	MPLG2_3453

TFU:

Tfu_0010

THAO:

NI17_020055

TALX:

FOF52_17095

NCG:	KGD84_27950

NOA:	BKM31_26205

AACD:

LWP59_00970

ATHM:

L1857_03680

ABAR:

AMYBAR_000198

PMI:	PMT9312_1346

MPRO:

BJP34_26850

LMAJ:

GKN94_04015

ATM:

ANT_06470

ABAT:

CFX1CAM_2129

PSUB:

Pelsub_P2657

LEK:	hrd7_00630

ABAO:

BEQ56_12835

PBF:	CFX0092_A3353

FNT:	HMPREF0405_00111

FVA:	FV113G1_31660

FPOL:

ERS445057_00375(spsE)

BGW:	VE98_C0001G0439

CGW:	UR58_C0001G0064

MAC:

MA_3767

MVC:	MSVAZ_0733

MEK:	MSKOL_0716

MHAZ:

BHR79_03025

MPOT:

BKM01_05440

MEND:

L6E24_09880

MAX:	MMALV_05370

NUE:	C5F50_00920

NIU:	DSQ19_09615

» show all

Reference

1 [PMID:13971393]

Authors

BLACKLOW RS, WARREN L.

Title

Biosynthesis of sialic acids by Neisseria meningitidis.

Journal

J Biol Chem 237:3520-6 (1962)

Reference

2 [PMID:9438985]

Authors

Komaki E, Ohta Y, Tsukada Y.

Title

Purification and characterization of N-acetylneuraminate synthase from Escherichia coli K1-M12.

Journal

Biosci Biotechnol Biochem 61:2046-50 (1997)
DOI:10.1271/bbb.61.2046

Other DBs

ExplorEnz - The Enzyme Database:

2.5.1.56

IUBMB Enzyme Nomenclature:

2.5.1.56

ExPASy - ENZYME nomenclature database:

2.5.1.56

BRENDA, the Enzyme Database:

2.5.1.56

CAS:	37290-66-7

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Gene (25080)   
   MGENES (23504)   
   RefGene (1576)   
Protein sequence (8127)   
   UniProt (1945)   
   RefSeq(pep) (6175)   
   PDBSTR (7)   
DNA sequence (30856)   
   RefSeq(nuc) (25528)   
   GenBank (2711)   
   EMBL (2617)   
3D Structure (7)   
   PDB (7)   
All databases (64070)   

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