KEGG ENZYME: 2.5.1.56

ENZYME: 2.5.1.56

Entry

EC 2.5.1.56                 Enzyme

Name

N-acetylneuraminate synthase;
(NANA)condensing enzyme;
N-acetylneuraminate pyruvate-lyase (pyruvate-phosphorylating);
NeuAc synthase

Class

Transferases;
Transferring alkyl or aryl groups, other than methyl groups;
Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)

Sysname

phosphoenolpyruvate:N-acetyl-D-mannosamine C-(1-carboxyvinyl)transferase (phosphate-hydrolysing, 2-carboxy-2-oxoethyl-forming)

Reaction(IUBMB)

phosphoenolpyruvate + N-acetyl-D-mannosamine + H2O = phosphate + N-acetylneuraminate [RN:R01804]

Reaction(KEGG)

R01804;
(other) R04435

Substrate

phosphoenolpyruvate [CPD:C00074];
N-acetyl-D-mannosamine [CPD:C00645];
H2O [CPD:C00001]

Product

phosphate [CPD:C00009];
N-acetylneuraminate [CPD:C00270]

History

EC 2.5.1.56 created 1972 as EC 4.1.3.19, transferred 2002 to EC 2.5.1.56

Pathway

ec00520

Amino sugar and nucleotide sugar metabolism

ec00541

O-Antigen nucleotide sugar biosynthesis

ec01100

Metabolic pathways

Orthology

K01654

N-acetylneuraminate synthase

K05304

sialic acid synthase

Genes

HSA:	54187(NANS)

PTR:	743934(NANS)

PPS:	100982112(NANS)

GGO:	101124502(NANS)

PON:	100446862(NANS)

NLE:	100603154(NANS)

HMH:	116475313(NANS)

MCC:	715459(NANS)

MCF:	102120030(NANS)

MTHB:

126938070

MNI:	105477199(NANS)

CSAB:

103219150(NANS)

CATY:

105593048(NANS)

PANU:

101020165(NANS)

TGE:	112607835(NANS)

MLEU:

105549289(NANS)

RRO:	104657773(NANS)

RBB:	108539113(NANS)

TFN:	117098940(NANS)

PTEH:

111536614(NANS)

CANG:

105509947(NANS)

CJC:	100411585(NANS)

SBQ:	101027621(NANS)

CIMI:

108303891(NANS)

CSYR:

103273474(NANS)

MMUR:

105873791(NANS)

LCAT:

123645941(NANS)

PCOQ:

105805371(NANS)

OGA:	100951418(NANS)

MMU:	94181(Nans)

MCAL:

110292645(Nans)

MPAH:

110323062(Nans)

RNO:	298071(Nans)

MCOC:

116095967(Nans)

ANU:	117709646(Nans)

MUN:	110551128(Nans)

CGE:	100767837(Nans)

MAUA:

101830178(Nans)

PROB:

127224641(Nans)

PLEU:

114702354(Nans)

MORG:

121458558(Nans)

MFOT:

126509881

AAMP:

119826497(Nans)

NGI:	103749137(Nans)

HGL:	101721582(Nans)

CPOC:

100716456(Nans)

CCAN:

109697287(Nans)

DORD:

105990839(Nans)

DSP:	122121805(Nans)

NCAR:

124964919

OCU:

100356934

OPI:	101522937(NANS)

TUP:	102496776(NANS)

GVR:	103590728(NANS)

CFA:	481624(NANS)

CLUD:

112649641(NANS)

VVP:	112930767(NANS)

VLG:	121494904(NANS)

AML:	100471912(NANS)

UMR:	103678504(NANS)

UAH:	113260417(NANS)

UAR:	123781029(NANS)

ELK:

111146174

LLV:

125083268

MPUF:

101687668(NANS)

NVS:	122917426(NANS)

ORO:	101377441(NANS)

EJU:	114213569(NANS)

ZCA:	113934273(NANS)

MLX:	118017911(NANS)

NSU:	110581438(NANS)

LWW:	102730978(NANS)

FCA:	101092303(NANS)

PYU:	121034713(NANS)

PCOO:

112872235(NANS)

PBG:	122474611(NANS)

LRUF:

124502196

PTG:	102952743(NANS)

PPAD:

109270098(NANS)

PUC:

125920084

AJU:	106981299(NANS)

HHV:	120233531(NANS)

BTA:	540602(NANS)

BOM:	102266035(NANS)

BIU:	109563072(NANS)

BBUB:

102402717(NANS)

BBIS:

104993691(NANS)

CHX:	102171423(NANS)

OAS:	101104048(NANS)

ODA:	120862645(NANS)

CCAD:

122452923(NANS)

SSC:	100155883(NANS)

CFR:	102511644(NANS)

CBAI:

105067382(NANS)

CDK:	105086903(NANS)

VPC:	102528094(NANS)

BACU:

103016138(NANS)

LVE:	103074242(NANS)

OOR:	101286113(NANS)

DLE:	111187968(NANS)

PCAD:

102975186(NANS)

PSIU:

116755813(NANS)

NASI:

112392669(NANS)

ECB:	100064126(NANS)

EPZ:	103550229(NANS)

EAI:	106842931(NANS)

MYB:	102254698(NANS)

MYD:	102770256(NANS)

MMYO:

118667273(NANS)

MLF:	102435662(NANS)

MNA:	107544993(NANS)

PKL:	118716275(NANS)

HAI:	109386412(NANS)

DRO:	112304493(NANS)

SHON:

118979589(NANS)

AJM:	119045927(NANS)

PDIC:

114509777(NANS)

PHAS:

123819942(NANS)

MMF:	118629683(NANS)

RFQ:	117032312(NANS)

PALE:

102882391(NANS)

PGIG:

120597479(NANS)

PVP:	105296243(NANS)

RAY:	107511690(NANS)

MJV:	108386331(NANS)

TOD:	119231857(NANS)

SARA:

101558462(NANS)

LAV:	100659127(NANS)

TMU:

101361417

ETF:	101653381(NANS)

DNM:	101415935(NANS)

MDO:	100014569(NANS)

GAS:	123231260(NANS)

SHR:	100915225(NANS)

AFZ:

127560750

PCW:	110220562(NANS)

OAA:	100074951(NANS)

GGA:	427283(NANS)

PCOC:

116234839(NANS)

MGP:	100540972(NANS)

CJO:	107306381(NANS)

NMEL:

110389693(NANS)

APLA:

101793548(NANS)

ACYG:

106046483(NANS)

AFUL:

116500909(NANS)

TGU:	100227675(NANS)

LSR:	110472303(NANS)

SCAN:

103821217(NANS)

PMOA:

120509468(NANS)

OTC:	121334701(NANS)

PRUF:

121355663(NANS)

GFR:	102036907(NANS)

FAB:	101817049(NANS)

PHI:	102108606(NANS)

PMAJ:

107198262(NANS)

CCAE:

111940921(NANS)

CCW:	104689769(NANS)

CBRC:

103616433(NANS)

ETL:	114056942(NANS)

ZAB:	102065706(NANS)

ACHL:

103804865(NANS)

SVG:	106859673(NANS)

FPG:	101910977(NANS)

FCH:	102058691(NANS)

CLV:	102088004(NANS)

EGZ:	104135026(NANS)

NNI:	104014067(NANS)

PLET:

104620779(NANS)

PCRI:

104025538(NANS)

PCAO:

104046970(NANS)

ACUN:

113489989(NANS)

TALA:

104366421(NANS)

PADL:

103923247(NANS)

AFOR:

103896158(NANS)

ACHC:

115336739(NANS)

HALD:

104312067(NANS)

HLE:	104830508(NANS)

AGEN:

126036494

GCL:

127027665

CCRI:

104155775(NANS)

CSTI:

104550675(NANS)

EHS:	104517044(NANS)

CMAC:

104481639(NANS)

FGA:	104074239(NANS)

GSTE:

104263825(NANS)

LDI:	104355132(NANS)

MNB:	103774718(NANS)

OHA:	104331297(NANS)

NNT:	104409114(NANS)

SHAB:

115601192(NANS)

DPUB:

104304859(NANS)

PGUU:

104469406(NANS)

ACAR:

104518859(NANS)

CPEA:

104394483(NANS)

AVIT:

104274354(NANS)

CVF:	104285719(NANS)

CUCA:

104059924(NANS)

TEO:	104375228(NANS)

BRHI:

104489142(NANS)

AAM:	106487451(NANS)

AROW:

112968978(NANS)

NPD:	112946284(NANS)

TGT:	104577698(NANS)

DNE:	112982754(NANS)

SCAM:

104151902(NANS)

ASN:	102371122(NANS)

AMJ:	102562418(NANS)

CPOO:

109323518(NANS)

CMY:	102930222(NANS)

CPIC:

101940249(NANS)

TST:	117878892(NANS)

CABI:

116832497(NANS)

MRV:	120408042(NANS)

ACS:	100558551(nans)

PVT:	110077827(NANS)

SUND:

121924222(NANS)

PBI:	103051012(NANS)

PMUR:

107293127(NANS)

CTIG:

120308567(NANS)

TSR:	106556782(NANS)

PGUT:

117661676(NANS)

VKO:	123030229(NANS)

PMUA:

114587657(NANS)

ZVI:	118097903(NANS)

HCG:	128346307(NANS)

GJA:	107122992(NANS)

STOW:

125437185(NANS)

XLA:	432051(nans.S) 447417(nans.L)

XTR:	100492893(nans)

NPR:	108783786(NANS)

RTEM:

120946942(NANS)

BBUF:

120989333(NANS)

BGAR:

122920937(NANS)

DRE:	322780(nansa) 492779(nansb)

SRX:	107723182 107754352 107754390 107758866

SANH:

107665955 107686966 107686967 107692601

SGH:	107557947 107566238 107566239

CCAR:

109076464 109090623 109090659

CAUA:

113044320 113066551 113066555 113066556 113066635 113085422 113105679

CGIB:

127946856 127946857 127948763 127975766

PPRM:

120475377(nansb) 120475384 120475385 120475386 120478311(nansa)

MAMB:

125247499 125247713 125247908 125247921 125248041 125251616 125251645 125272478(nansa)

CIDE:

127507296 127519832

MASI:

127443667 127445253

IPU:	100528493(nansa) 108260162

PHYP:

113531522(nans)

SMEO:

124378730 124381237(nansa)

TFD:	113635339(nansa)

AMEX:

111195185(nans)

EEE:	113568448(nans) 113589926

TRU:	778024(nans)

TNG:	GSTEN00033532G001

LCO:	104922341(nans)

CGOB:

115010173 115010214

ELY:	117254746(nansa)

EFO:	125885917(nansa)

PLEP:

121942582(nansa)

SLUC:

116042899(nansa)

ECRA:

117956637(nansa)

ESP:	116698406(nans)

PFLV:

114570372(nans)

GAT:	120825501 120825503

PPUG:

119218410(nansa)

MSAM:

119884880 119899378 119899379

CUD:	121507902 121508708 121508709

ALAT:

119028006

MZE:	101481190 106674567

ONL:	100695579 100695847 100696106

OAU:	116310552 116310553 116310587

OLA:	101166198(nans)

OML:	112137589(nansa)

XMA:	102234709(nans)

XCO:	114145362(nans)

XHE:	116720640(nans)

PRET:

103467988(nans) 103472627

PFOR:

103148741(nans)

PLAI:

106938624(nans)

PMEI:

106905478(nans)

GAF:	122829775(nansa)

CVG:	107083396(nans) 107083415 107083416

CTUL:

119787144 119787154 119787177

GMU:	124868545 124868562

NFU:	107390917 107390934

KMR:	108241432 108241509

ALIM:

106528334(nans)

NWH:	119422378 119422379

AOCE:

111575007(nans)

MCEP:

125003896 125004087 125004788

CSEM:

103384124 103384125

POV:	109627210 109627438

SSEN:

122770577 122771631

HHIP:

117769790 117769798

HSP:	118122966 118126039

LCF:	108885367 108885368

SDU:	111229256 111229269

SLAL:

111656109 111659703

XGL:	120800959(nansa)

HCQ:	109519806 109519931

SSCV:

125969199 125969200

BPEC:

110166192 110166235

MALB:

109953770(nans)

BSPL:

114858266 114858277 114858282

SASA:

100195066(sias) 106594767 106609889

STRU:

115191851 115202178 115202179 115202180 115202181

OTW:	112231840 112261351

OMY:	110497423 110497424 110534455

OGO:	124001941 124001943 124012735

ONE:	115137363 115137722 115145762 115146546

SALP:

111971593 112068285 112080022

SNH:	120034903 120051990 120052901

CCLU:

121534521 121535761 121535762

ELS:	105022900(nans)

SFM:

108920829

PKI:	111855408(nans)

AANG:

118227907(nansa)

LOC:	102687418(nans)

PSPA:

121319344(nansa)

ARUT:

117420829(nansa)

PSEX:

120532357 120532358 120532359

CMK:	103177631(nansa) 103177633

RTP:	109938218(nans)

CPLA:

122539555(nansa) 122547124

BFO:	118412951 118412952

BBEL:

109471483 109471485

SCLV:

120347367

SPU:

577884

APLC:

110979925

AJC:

117102584

SKO:	100367009 100376912

DME:	Dmel_CG5232(NANS)

DER:

6553702

DSE:

6606666

DSI:	Dsimw501_GD18832(Dsim_GD18832)

DYA:	Dyak_GE26192

DSR:

110190443

DPO:

4800832

DPE:

6598731

DMN:

108156913

DWI:

6650267

DGR:

6568185

DMO:	Dmoj_GI24828

DAZ:

108621816

DNV:

108653385

DHE:

111601415

CCAT:

101459749

BOD:

106619099

RZE:

108365099

MDE:

101899077

SCAC:

106086863

LCQ:

111687367

LSQ:

119609198

HIS:

119658663

AGA:	AgaP_AGAP004460

ACOZ:

120950612

AARA:

120897604

AMER:

121589583

ASTE:

118508544

AAG:

5563645

AALB:

109400878

CQU:	CpipJ_CPIJ013964

CPII:

120415920

CNS:

116345828

BCOO:

119073869

TCA:

103312199

DPA:

109539228

SOY:

115879752

ATD:

109597067

CSET:

123315673

AGB:

108917229

LDC:

111503205

NVL:

108567369

APLN:

108741788 112904754

PPYR:

116164831

BMOR:

101744099

BMAN:

114246626

MSEX:

115444962

DPL:	KGM_201756

BANY:

112054184

NIQ:

126781032

PMAC:

106708951 106709065

PPOT:

106100777 106100789

PXU:	106124172 106124788

PRAP:

110994857

PBX:

123716686

PNAP:

125054681

ZCE:

119829783

CCRC:

123693416

HAW:

110380482

HZE:

124629863

TNL:	113496613 113506267

SLIU:

111353605

OFU:

114364386

PXY:

105391284

API:	100166349 100570600

DNX:

107161705

AGS:

114120104

RMD:

113549718

BTAB:

109035180

DCI:

103520284

CLEC:

106666066

HHAL:

106681070

NLU:

111058090

PHU:	Phum_PHUM018360

FOC:

113212662

TPAL:

117647422

ZNE:

110829049

CSEC:

111874253

SGRE:

126267101

FCD:

110842189

DPX:	DAPPUDRAFT_300651

DMK:

116933060

DPZ:

124349840

PVM:

113802701

PJA:

122265930

PCHN:

125046868

PMOO:

119575012

HAME:

121873235

PCLA:

123769285

PTRU:

123507890

ESN:

126997930

HAZT:

108677748

EAF:

111695997

PPOI:

119112814 119113236

VDE:

111250001

VJA:

111258697

TUT:

107368038

CSCU:

111619307

PTEP:

107452120

SDM:

118205491

MMER:

123559815

AAF:	AURANDRAFT_30675

EHX:	EMIHUDRAFT_437804(NEUB)

ECOO:

ECRM13514_2762(nnaB)

ECOH:

ECRM13516_2630(nnaB)

ESL:

O3K_09230

ESO:

O3O_16390

ESM:

O3M_09195

ECK:	EC55989_2295

ECV:	APECO1_3471(neuB)

ECM:	EcSMS35_3232(neuB)

ECT:	ECIAI39_3443(neuB)

EOC:	CE10_3481(neuB)

ECI:	UTI89_C3372(neuB)

EIH:	ECOK1_3369(neuB)

ECZ:	ECS88_3330(neuB)

ECOI:

ECOPMV1_03252(spsE)

SBZ:

A464_2222

SBV:	N643_09315

PPAV:

LOZ86_01605

PTT:	VY86_07610

EIC:	NT01EI_1316

ETR:	ETAE_1207(neuB)

ETD:

ETAF_1122

ETE:	ETEE_3151(neuB)

ETC:	ETAC_05745

EDW:	QY76_14240

EDL:	AAZ33_06215(neuB)

EHO:	A9798_10695

HPR:	PARA_02850(nnaB)

MHT:	D648_18140(neuB)

MHQ:	D650_8020(neuB)

MHAT:

B824_18220(neuB)

MHX:	MHH_c26670(nnaB)

MHAE:

F382_04090

MHAM:

J450_03120

MHAO:

J451_04330

MHAL:

N220_10190

MHAQ:

WC39_04015

MHAY:

VK67_04015

MVR:

X781_5990

MVI:	X808_15570

MVG:	X874_14510

MVE:

X875_5510

MGRA:

A4G16_01260

MBOS:

ICJ55_05335(neuB)

ASI:	ASU2_01185 ASU2_10545

ASS:	ASU1_01190

AEU:	ACEE_01045

ADP:	NCTC12871_01316(spsE)

APAG:

EIA51_04610(neuB)

RPNE:

NCTC8284_01156(spsE)

RHEY:

FEE42_11160(neuB)

VSA:	VSAL_I3011(neuB)

PGB:	H744_2c2918

PAEW:

KIH87_04060

MMAI:

sS8_2961

MISZ:

MishRS11D_42600

FSR:	KQR59_06225

IFO:	CVFO_1265(neuB)

NME:	NMB0068(siaC)

NMP:	NMBB_0073(siaC)

NMH:	NMBH4476_0068

NMD:	NMBG2136_0075

NMM:	NMBM01240149_0067

NMS:	NMBM01240355_0070

NMQ:	NMBM04240196_0082(siaC)

NMZ:	NMBNZ0533_0074(siaC)

NMC:	NMC0052(siaC)

NMN:	NMCC_0076(siaC)

NMT:	NMV_0069(siaC)

NWE:	SAMEA3174300_1366(siaC)

NBL:	GJV52_06945(siaC)

SMUR:

BWP33_01885

RPJ:	N234_26965

BPSI:

IX83_06875

NCO:	AAW31_00110

NMU:	Nmul_A0408

NLC:	EBAPG3_000870

SLAC:

SKTS_36140

DDEN:

KI615_14890

EAH:	FA04_24335

EAK:	EKH55_4784

REL:	REMIM1_CH00773

RLG:

Rleg_0440

RHV:	BA939_07200

RRG:	J3P73_04755

RPE:

RPE_4236

MMYR:

MXMO3_03623

BVR:

BVIR_1970

BLAG:

BLTE_00400(neuB)

CMET:

K6K41_27370

HDI:	HDIA_0896(pseI)

LAP:	ACP90_17630

LABR:

CHH27_23610

LABT:

FIU93_24290(neuB)

LAGG:

B0E33_01050 B0E33_04290

SIW:	GH266_06020

CAK:

Caul_2713

MALG:

MALG_05073

PSEB:

EOK75_20575

PGV:	SL003B_2768

CBOT:

ATE48_13380

SPAN:

AWL63_07225

SPZR:

G5C33_06875

PALG:

HFP57_17520

CMAN:

A9D14_11725

AZZ:	DEW08_29995

RCE:	RC1_3771(nans)

DEX:	HWD60_03420

HFL:	PUV54_04660

HBL:	XJ32_01820

CJE:	Cj1141(neuB1)

CJB:	BN148_1141(neuB1)

CJJ:	CJJ81176_1158

CJU:

C8J_1339

CJN:	ICDCCJ07001_1099

CJI:	CJSA_1083(neuB1)

CJP:	A911_05530

CJEJ:

N564_01107

CJEU:

N565_01150

CJEN:

N755_01145

CJEI:

N135_01178

CJY:	QZ67_01219(legI_1)

CJL:	PJ17_05840

CJW:	PJ18_05655

CJZ:	M635_01405

CCOL:

BN865_09890c

CCY:	YSS_06165 YSS_07645

CIS:	CINS_1205(neuB)

CSM:	CSUB8521_1427(neuB)

CAVI:

CAV_0275(neuB)

CHW:	A2J15_001225

CUX:	CUP3940_0880(neuB)

CMUC:

CMCT_1128(neuB)

CNV:	CNZW441b_1143(neuB)

CVU:	CVULP_0717(neuB)

ARC:

ABLL_2687

AHS:	AHALO_2546

AMYT:

AMYT_2597

HEBR:

AEBR_0577 AEBR_2874

PCA:	Pcar_1277(neuB)

DVM:

DvMF_1832

DEF:	CNY67_09315

DFL:

DFE_1272

DSD:	GD606_11120

DMA:

DMR_13530

DCB:	C3Y92_14295

DGG:

DGI_4066

DMS:	E8L03_20250

DAF:	Desaf_0142

DAS:

Daes_2970

DPI:

BN4_12645

DEJ:	AWY79_17810

PPRF:

DPRO_1430

PSEL:

GM415_02085 GM415_02270

DDN:	DND132_2824

PSEF:

PSDVSF_27550

PPOR:

JCM14722_23280

DSX:	GD604_00905

DALK:

DSCA_06450

TAV:	G4V39_08720

MRM:	A7982_08421

HOH:

Hoch_0346

HLI:

HLI_08585

GRC:	GI584_08485

BOU:	I5818_06175

LGZ:	NCTC10812_01041(spsE)

PYG:	AWM70_17110

SAG:	SAG1161(neuB)

SAN:

neuB

SAK:	SAK_1250(neuB)

SGC:	A964_1134(neuB)

SAGS:

SaSA20_0983(neuB)

SAGL:

GBS222_0993(neuB)

SAGM:

BSA_12390

SAGI:

MSA_12810

SAGR:

SAIL_12810

SAGP:

V193_05425

SAGC:

DN94_05425

SAGT:

GBSCOH1_1067

SAGE:

EN72_06455

SAGG:

EN73_05990

SAGN:

W903_1244(neuB)

SAGJ:

ID870_03555(neuB)

SSB:	SSUBM407_1280(neuB)

SSU:	SSU05_0578

SSV:	SSU98_0582

SSI:	SSU0535(neuB)

SSS:	SSUSC84_0517(neuB)

SSF:	SSUA7_0538

SSW:	SSGZ1_0571

SUP:

YYK_02535

SSUS:

NJAUSS_0543

SUI:	SSUJS14_0542

SUO:	SSU12_0539

SRP:	SSUST1_1227

SSUT:

TL13_1188(neuB)

SSUI:

T15_1401(neuB)

SRQ:	SR187_6425

AUH:	AWM75_07800

CBK:

CLL_A2336

CRW:	CROST_020640(legI)

CFB:	CLFE_020550(legI)

CAUN:

CLAUR_009290(legI)

ACEL:

acsn021_05140

RGN:	RGna_11985(neuB)

SINT:

K5I26_06365(neuB)

CLC:	Calla_1077

TTO:	Thethe_00855

MAUU:

NCTC10437_01405(spsE)

SCO:	SCO4881(2SCK8.07)

SALB:

XNR_3962

SMA:	SAVERM_3373(neuB)

SGR:

SGR_2659

SGB:

WQO_22260

SCB:	SCAB_35021

SSX:	SACTE_4137

SVL:	Strvi_8579

SHY:

SHJG_5999

SHO:	SHJGH_5761

SRC:	M271_28825

SMAL:

SMALA_3271

SSOI:

I1A49_20150

SFA:

Sfla_2375

SBH:

SBI_04660

SVE:

SVEN_4550

SDV:	BN159_3517

SALS:

SLNWT_4806

STRP:

F750_4425

SFI:

SFUL_4686

SCI:	B446_22900

SLV:	SLIV_13970

SGU:	SGLAU_21015

SVT:	SVTN_23655

STRE:

GZL_03800

SCW:	TU94_20415

SLD:

T261_3148

SLC:	SL103_31275

SXI:	SXIM_34600

STRM:

M444_21440

STRC:

AA958_21930

SAMB:

SAM23877_4702

SPRI:

SPRI_2992

SCZ:	ABE83_12980

SCX:	AS200_19310

SRW:	TUE45_05421(legI)

STRF:

ASR50_22385

SLE:	sle_27930(sle_27930)

SRN:	A4G23_03558(legI)

SPAV:

Spa2297_20655

STRT:

A8713_19580

SCLF:

BB341_09760

SGS:	AVL59_05150

STSI:

A4E84_25245

SKY:	D0C37_21440

SALW:

CP975_21860

SGM:	GCM10017557_30090

SCAD:

DN051_15990

SPHW:

NFX46_04655

SLS:	SLINC_5269

SNR:	SNOUR_16850

SALU:

DC74_5067

SALL:

SAZ_27045

SPLU:

LK06_020555

STRD:

NI25_14545

SNW:	BBN63_12045

SAUO:

BV401_19850

SSIA:

A7J05_14200

SVU:	B1H20_22760

SPUN:

BFF78_16590

SGV:	B1H19_25585

SLAU:

SLA_4740 SLA_6887

SALF:

SMD44_05468

SALJ:

SMD11_2618

SLX:	SLAV_09960(legI1) SLAV_15140(legI2)

STRO:

STRMOE7_24205

SFK:

KY5_4998

SNZ:	DC008_21770

SGE:	DWG14_03226(legI)

SRJ:

SRO_2876

SLK:	SLUN_24770

SDX:	C4B68_15075

SGD:	ELQ87_14885

SCYA:

EJ357_28925

SAST:

CD934_06470 CD934_12310

SNQ:	CP978_20885

STIR:

DDW44_18845

SKA:	CP970_16280

SVN:	CP980_13090

SNK:	CP967_05875 CP967_12450

SHAW:

CEB94_25645

SRK:	FGW37_20385

SFIC:

EIZ62_12135

SGAL:

CP966_22765

SSPO:

DDQ41_21630

SPAD:

DVK44_22020

SFY:	GFH48_16540

SAQU:

EJC51_30275

SGF:	HEP81_03086

SCAV:

CVT27_21580

SSEO:

D0Z67_18105

SBY:	H7H31_21570

SRIM:

CP984_14855

SSUB:

CP968_13205

SPHV:

F9278_31615

SCIN:

CP977_21415

SFUG:

CNQ36_22015

SPAC:

B1H29_14045

SCHA:

CP983_16290

SGX:	H4W23_25065

SCOE:

CP976_27090

SBAT:

G4Z16_11340

SSPB:

CP982_26255

SNF:	JYK04_05256(legI)

SPLA:

CP981_24345

SBRO:

GQF42_26950

STUI:

GCM10017668_44270

SATA:

C5746_25680

SCHF:

IPT68_22475

SHUN:

DWB77_03039(legI)

SHAR:

HUT13_17550

SCYG:

S1361_24370(legI)

SFEU:

IM697_39420

SLIA:

HA039_12440

SDW:	K7C20_23210

SVD:	CP969_24060

SCAL:

I6J39_22415

SAUH:

SU9_021505

SFB:	CP974_19285

SMOB:

J7W19_20110

SPRA:

CP972_22240

SPEU:

CGZ69_22020

SROI:

IAG44_14945

SXN:	IAG42_13295

SGJ:	IAG43_19675

SHK:	J2N69_22950

SANU:

K7396_13775

STRY:

EQG64_22470

SDD:	D9753_13435

SACT:

DMT42_24315

SMAO:

CAG99_08790

SGOB:

test1122_17165

SINE:

KI385_28310

SLF:	JEQ17_18230

SDEC:

L3078_29100

SAOV:

G3H79_13490

SDUR:

M4V62_17340

SYAN:

NRK68_20945

SRUG:

F0345_09840

SAKB:

K1J60_16260

STAA:

LDH80_15810

SNIG:

HEK616_61380

SVIO:

HWN34_20045

SCT:

SCAT_3775

SCY:	SCATT_37620

KAB:	B7C62_23005

STRI:

C7M71_012340

ABRY:

NYE86_30650

MIM:	AKG07_08990

MIX:	AB663_000207

MCW:	A8L33_09345

MICR:

BMW26_13440

MFOL:

DXT68_13545

MOO:	BWL13_02917(legI)

MPRT:

ET475_05105

MSED:

E3O41_07295

MOY:	CVS54_03075(legI)

MRN:	K8F61_13810

MLIQ:

NMQ05_14905

MTEC:

OAU46_11045

RTX:	TI83_02490

RTC:	APU90_03985

RRY:	C1O28_12555

CUB:	BJK06_02800

CUG:	C1N91_04585

AGY:	ATC03_06050

AGM:	DCE93_10975

AGF:	ET445_07850

AMAU:

DSM26151_22300(legI)

ASOI:

MTP13_09910

PSAI:

C3B54_111626

HUW:	FPZ11_09370

GRY:	D7I44_05085

LYK:	FLP23_10985

PLAP:

EAO79_15945

GLN:	F1C58_04720

HOM:	OF852_09430

ARL:	AFL94_17655

ARY:	ATC04_00745

ACRY:

AC20117_06350

ASUF:

MNQ99_01110

APN:	Asphe3_30650

AAI:	AARI_34160

GAR:	AOZ07_17865

GCR:	GcLGCM259_2956

GLU:	F0M17_16915

GPR:	JQN66_17680

GMI:	NMP99_17285

GMY:

XH9_08625

PAEY:

KUF55_18490

JDE:

Jden_0843

SANW:

G7063_04465

CGA:	Celgi_1077

CEZ:	CBP52_08110

CPAL:

F1D97_14765

BLY:	A2T55_13610

BLIN:

BLSMQ_3040

BRI:	FDF13_06745

BLUT:

EW640_07300

BCAU:

I6G59_00015

MPH:

MLP_28480

MIK:	FOE78_14365

AER:	AERYTH_11775

MGG:	MPLG2_3453

TFU:

Tfu_0010

THAO:

NI17_020055

TALX:

FOF52_17095

NOA:	BKM31_26205

AACD:

LWP59_00970

ATHM:

L1857_03680

PMI:	PMT9312_1346

MPRO:

BJP34_26850

ATM:

ANT_06470

ABAT:

CFX1CAM_2129

PSUB:

Pelsub_P2657

LEK:	hrd7_00630

ABAO:

BEQ56_12835

PBF:	CFX0092_A3353

LPRO:

PQO03_09635

TBE:	Trebr_1643

SSM:	Spirs_4263

BHP:	BHAMNSH16_00325

ABA:	Acid345_2841

GMA:	AciX8_3329

GRB:	GOB94_15720

ABAS:

ACPOL_2207

SUS:

Acid_2246

FNT:	HMPREF0405_00111

FVA:	FV113G1_31660

BHL:	Bache_2153

BFE:	K6V30_22135

BSA:	Bacsa_3466

PCLR:

PC1C4_16490 PC1C4_23910

ALKQ:

M9189_10535

PGIN:

FRZ67_17740

FEI:	K9M53_13105

MUP:	A0256_06345

MUC:

MuYL_3260

MGK:	FSB76_19830

MRUB:

DEO27_006375

MMAB:

HQ865_03405

MJJ:	PQO05_17985

SPIB:

G8759_19535

CHRW:

KA713_16020

RHOZ:

GXP67_24460

RSI:	Runsl_2328

RUN:	DR864_20420

RUP:	DTQ70_21560

HYG:	AUC43_17190

HYP:	A0257_12515 A0257_22870

HYZ:	AXW84_01635

HNV:	DDQ68_17445

HMT:	MTP16_14775

FYA:	KMW28_01745

FJG:	BB050_02206(legI)

FCO:	FCOL_12635

FGL:	EM308_00620

FCM:	BIW12_03115

FFA:	FFWV33_07925

FCR:	HYN56_01615

FEN:	J0383_14490

FCV:	AWN65_10295

FCS:	TRV642_0311

CAT:	CA2559_07305

KDI:	Krodi_2064

DOK:	MED134_13631(neuB)

DDO:	I597_1525(legI)

DOD:	DCS32_01450

NDO:

DDD_2293

NOM:	AAT17_10860

NSD:	BST91_07935

NOB:	CW736_00515

PRN:	BW723_03025 BW723_09690

LUT:	Lupro_02285

OLL:	CW732_09090

TAJ:	C1A40_00900

AUE:	C5O00_09755

AQA:	D1815_16910

EMAR:

D1013_15690

MESQ:

C7H62_1954

SABU:

MBM09_06180

BBAU:

AEM51_01345

CTE:

CT0825

CPC:

Cpar_0852

CLZ:	BIU88_06970

CCH:

Cag_1072

CPH:	Cpha266_1187

CLI:

Clim_0797

PVI:

Cvib_1025

PLT:

Plut_1274

PPH:

Ppha_1574

PAA:

Paes_0910

PRS:	B9H02_06625

CTS:

Ctha_2574

IAL:	IALB_1518(neuB)

MRO:

MROS_1489

BGW:	VE98_C0001G0439

CGW:	UR58_C0001G0064

MAC:

MA_3767

MVC:	MSVAZ_0733

MEK:	MSKOL_0716

MHAZ:

BHR79_03025

MEND:

L6E24_09880

MAX:	MMALV_05370

NUE:	C5F50_00920

NIU:	DSQ19_09615

» show all

Reference

1 [PMID:13971393]

Authors

BLACKLOW RS, WARREN L.

Title

Biosynthesis of sialic acids by Neisseria meningitidis.

Journal

J Biol Chem 237:3520-6 (1962)

Reference

2 [PMID:9438985]

Authors

Komaki E, Ohta Y, Tsukada Y.

Title

Purification and characterization of N-acetylneuraminate synthase from Escherichia coli K1-M12.

Journal

Biosci Biotechnol Biochem 61:2046-50 (1997)
DOI:10.1271/bbb.61.2046

Other DBs

ExplorEnz - The Enzyme Database:

2.5.1.56

IUBMB Enzyme Nomenclature:

2.5.1.56

ExPASy - ENZYME nomenclature database:

2.5.1.56

BRENDA, the Enzyme Database:

2.5.1.56

CAS:	37290-66-7

DBGET integrated database retrieval system