Entry
Name
[amino-group carrier protein]-L-glutamate 6-kinase;
lysZ (gene name)
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a carboxy group as acceptor
BRITE hierarchy
Sysname
[amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamine 5-O-kinase
Reaction(IUBMB)
ATP + an [amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate = ADP + an [amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate [RN:
R10930 ]
Reaction(KEGG)
Substrate
ATP [CPD:
C00002 ];
[amino-group carrier protein]-C-terminal-gamma-(L-glutamyl)-L-glutamate
Product
ADP [CPD:
C00008 ];
[amino-group carrier protein]-C-terminal-gamma-(5-phospho-L-glutamyl)-L-glutamate [CPD:
C20949 ]
Comment
The enzyme participates in an L-arginine biosynthetic pathway in certain species of archaea. In some organisms the enzyme also catalyses the activity of EC
2.7.2.17 , [amino-group carrier protein]-L-2-aminoadipate 6-kinase.
History
EC 2.7.2.19 created 2022
Pathway
Orthology
K05828 [amino group carrier protein]-L-2-aminoadipate/L-glutamate 6-kinase
Genes
SNK : CP967_01840 CP967_15195
SROC : RGF97_02775 RGF97_22060
HARC : HARCEL1_01515(argB)
STO : STK_01940(argB_lysZ)
» show all
Taxonomy
Reference
Authors
Ouchi T, Tomita T, Horie A, Yoshida A, Takahashi K, Nishida H, Lassak K, Taka H, Mineki R, Fujimura T, Kosono S, Nishiyama C, Masui R, Kuramitsu S, Albers SV, Kuzuyama T, Nishiyama M
Title
Lysine and arginine biosyntheses mediated by a common carrier protein in Sulfolobus.
Journal
Sequence
Reference
Authors
Yoshida A, Tomita T, Atomi H, Kuzuyama T, Nishiyama M
Title
Lysine Biosynthesis of Thermococcus kodakarensis with the Capacity to Function as an Ornithine Biosynthetic System.
Journal
Sequence
Other DBs
ExplorEnz - The Enzyme Database: 2.7.2.19
ExPASy - ENZYME nomenclature database: 2.7.2.19