KEGG   ENZYME: 2.7.4.32
Entry
EC 2.7.4.32                 Enzyme                                 

Name
farnesyl phosphate kinase
Class
Transferases;
Transferring phosphorus-containing groups;
Phosphotransferases with a phosphate group as acceptor
Sysname
CTP:(2E,6E)-farnesyl-phosphate phosphotransferase
Reaction(IUBMB)
CTP + (2E,6E)-farnesyl phosphate = CDP + (2E,6E)-farnesyl diphosphate [RN:R09850]
Reaction(KEGG)
R09850
Substrate
CTP [CPD:C00063];
(2E,6E)-farnesyl phosphate [CPD:C20121]
Product
CDP [CPD:C00112];
(2E,6E)-farnesyl diphosphate [CPD:C00448]
Comment
The enzyme, found in plants and animals, is specific for CTP as phosphate donor. It does not use farnesol as substrate (cf. EC 2.7.1.216, farnesol kinase).
History
EC 2.7.4.32 created 2017
Pathway
ec00900  Terpenoid backbone biosynthesis
ec01110  Biosynthesis of secondary metabolites
Reference
1  [PMID:9606952]
  Authors
Bentinger M, Grunler J, Peterson E, Swiezewska E, Dallner G
  Title
Phosphorylation of farnesol in rat liver microsomes: properties of farnesol kinase and farnesyl phosphate kinase.
  Journal
Arch Biochem Biophys 353:191-8 (1998)
DOI:10.1006/abbi.1998.0611
Reference
2  [PMID:21395888]
  Authors
Fitzpatrick AH, Bhandari J, Crowell DN.
  Title
Farnesol kinase is involved in farnesol metabolism, ABA signaling and flower development in Arabidopsis.
  Journal
Plant J 66:1078-88 (2011)
DOI:10.1111/j.1365-313X.2011.04572.x
Other DBs
ExplorEnz - The Enzyme Database: 2.7.4.32
IUBMB Enzyme Nomenclature: 2.7.4.32
ExPASy - ENZYME nomenclature database: 2.7.4.32
BRENDA, the Enzyme Database: 2.7.4.32

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